Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1824, Issue 2, 2012, Pages 274-285

  Andreasen, Maria ^a   Nielsen, Søren B ^a   Mittag, Tina ^a   Bjerring, Morten ^a   Nielsen, Jakob T ^a   Zhang, Shuai ^b   Nielsen, Erik H ^a   Jeppesen, Martin ^a   Christiansen, Gunna ^b   Besenbacher, Flemming ^b   Dong, Mingdong ^b   Nielsen, Niels Chr ^a   Skrydstrup, Troels ^a   Otzen, Daniel E ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Amylin; Amyloid formation; Critical aggregation concentration; Peptide analog; Seeding

Indexed keywords

AMYLIN; HYDROGEN; NITROGEN; PEPTOID;

ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; FIBER; FIBRILLATION; HORMONE ACTION; HYDROGEN BOND; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; PEPTIDE BACKBONE; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMYLOID; DIABETES MELLITUS, TYPE 2; DIPEPTIDES; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; METHYLATION; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, TRANSMISSION; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEPTOIDS; PROTEIN STRUCTURE, SECONDARY; SPECTRUM ANALYSIS; X-RAY DIFFRACTION;

EID: 83055192097     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2011.10.014     Document Type: Article

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