Running loose or getting lost: How HIV-1 counters and capitalizes on APOBEC3-induced mutagenesis through Its Vif protein

Viruses

Volumn 4, Issue 11, 2012, Pages 3132-3161

  Münk, Carsten ^a   Jensen, Björn Erik O ^a   Zielonka, Jörg ^a,b   Häussinger, Dieter ^a   Kamp, Christel ^c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Roche Glycart AG   (Switzerland)

^c PAUL EHRLICH INSTITUT   (Germany)

Author keywords

APOBEC3; Coevolution; Drug resistance; Escape mutant; HIV 1; Modeling; Population genetics; Quasispecies; Vif

Indexed keywords

ANTIRETROVIRUS AGENT; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 2; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3A; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3B; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3D; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3F; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 4; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE LIKE 3; DOUBLE STRANDED DNA; POLYPEPTIDE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; VIF PROTEIN; VIRUS DNA; VIRUS RNA;

ADAPTIVE IMMUNITY; DISEASE COURSE; DNA DAMAGE; DNA REPLICATION; ENVIRONMENTAL FACTOR; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IN VIVO STUDY; MICROBIAL ACTIVITY; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REGULATORY MECHANISM; REVIEW; VIRAL GENETICS; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS INFECTIVITY; VIRUS INHIBITION; VIRUS MUTATION; VIRUS PARTICLE; VIRUS RECOMBINANT; VIRUS RECOMBINATION; VIRUS REPLICATION; VIRUS RESISTANCE;

BIOLOGICAL EVOLUTION; CYTOSINE DEAMINASE; DRUG RESISTANCE, VIRAL; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MUTAGENESIS; VIF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84870608030     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v4113132     Document Type: Review

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