Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation

Structure

Volumn 20, Issue 12, 2012, Pages 2048-2061

  Ferrage, Fabien ^a,b   Dutta, Kaushik ^c   Nistal Villán, Estanislao ^b,d   Patel, Jenish R ^b   Sánchez Aparicio, María T ^b   De Ioannes, Pablo ^b   Buku, Angeliki ^b   Aseguinolaza, Gloria González ^d   García Sastre, Adolfo ^b   Aggarwal, Aneel K ^b  

^a ECOLE NORMALE SUPÉRIEURE   (France)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

^d UNIVERSITY OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; CASPASE RECRUITMENT DOMAIN PROTEIN 1; CASPASE RECRUITMENT DOMAIN PROTEIN 2; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

ARTICLE; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STRUCTURE ANALYSIS; UBIQUITINATION;

AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; DEAD-BOX RNA HELICASES; HEK293 CELLS; HUMANS; INTERFERON-BETA; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHOPROTEINS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; SURFACE PROPERTIES; TRANSCRIPTIONAL ACTIVATION; UBIQUITINATION;

EID: 84870502910     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.09.003     Document Type: Article

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