Reduced TCR signaling potential impairs negative selection but does not result in autoimmune disease

Journal of Experimental Medicine

Volumn 209, Issue 10, 2012, Pages 1781-1795

  Hwang, Su Jin ^a   Song, Ki Duk ^a,b   Lesourne, Renaud ^a,c   Lee, Jan ^a   Pinkhasov, Julia ^a,d   Li, LiQi ^a   El Khoury, Dalal ^a   Love, Paul E ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b Seoul National University   (South Korea)

^c France   (France)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL SELECTION; EMBRYONIC STEM CELL; GENE SILENCING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE RECEPTOR GENE; THYMOCYTE; THYMUS;

ALLELES; ANIMALS; AUTOIMMUNE DISEASES; BONE MARROW TRANSPLANTATION; CLONAL SELECTION, ANTIGEN-MEDIATED; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; GENE ORDER; HOMEODOMAIN PROTEINS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, TRANSGENIC; MUTATION; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; THYMOCYTES;

EID: 84870284512     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20120058     Document Type: Article

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