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Volumn 184, Issue 5, 2010, Pages 2476-2486

The role of the LAT-PLC-γ1 interaction in T regulatory cell function

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; LAT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PLC GAMMA 1 PROTEIN; PROTEIN; T LYMPHOCYTE RECEPTOR; TAMOXIFEN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; LAT PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 77951902637     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0902876     Document Type: Article
Times cited : (51)

References (46)
  • 1
    • 0032498231 scopus 로고    scopus 로고
    • LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
    • DOI 10.1016/S0092-8674(00)80901-0
    • Zhang, W., J. Sloan-Lancaster, J. Kitchen, R. P. Trible, and L. E. Samelson. 1998. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92: 83-92. (Pubitemid 28053300)
    • (1998) Cell , vol.92 , Issue.1 , pp. 83-92
    • Zhang, W.1    Sloan-Lancaster, J.2    Kitchen, J.3    Trible, R.P.4    Samelson, L.E.5
  • 2
    • 0032489913 scopus 로고    scopus 로고
    • Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells
    • Weber, J. R., S. Orstavik, K. M. Torgersen, N. C. Danbolt, S. F. Berg, J. C. Ryan, K. Taskén, J. B. Imboden, and J. T. Vaage. 1998. Molecular cloning of the cDNA encoding pp36, a tyrosine-phosphorylated adaptor protein selectively expressed by T cells and natural killer cells. J. Exp. Med. 187: 1157-1161.
    • (1998) J. Exp. Med. , vol.187 , pp. 1157-1161
    • Weber, J.R.1    Orstavik, S.2    Torgersen, K.M.3    Danbolt, N.C.4    Berg, S.F.5    Ryan, J.C.6    Taskén, K.7    Imboden, J.B.8    Vaage, J.T.9
  • 3
    • 0032992072 scopus 로고    scopus 로고
    • Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line
    • Zhang, W., B. J. Irvin, R. P. Trible, R. T. Abraham, and L. E. Samelson. 1999. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. Int. Immunol. 11: 943-950.
    • (1999) Int. Immunol. , vol.11 , pp. 943-950
    • Zhang, W.1    Irvin, B.J.2    Trible, R.P.3    Abraham, R.T.4    Samelson, L.E.5
  • 4
    • 0034725625 scopus 로고    scopus 로고
    • Association of Grb2, Gads, and phospholipase C-γ1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
    • Zhang, W., R. P. Trible, M. Zhu, S. K. Liu, C. J. McGlade, and L. E. Samelson. 2000. Association of Grb2, Gads, and phospholipase C-γ1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J. Biol. Chem. 275: 23355-23361.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23355-23361
    • Zhang, W.1    Trible, R.P.2    Zhu, M.3    Liu, S.K.4    McGlade, C.J.5    Samelson, L.E.6
  • 5
    • 0032212728 scopus 로고    scopus 로고
    • LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway
    • Finco, T. S., T. Kadlecek, W. Zhang, L. E. Samelson, and A. Weiss. 1998. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity 9: 617-626.
    • (1998) Immunity , vol.9 , pp. 617-626
    • Finco, T.S.1    Kadlecek, T.2    Zhang, W.3    Samelson, L.E.4    Weiss, A.5
  • 6
    • 0037221580 scopus 로고    scopus 로고
    • Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development
    • Zhu, M., E. Janssen, and W. Zhang. 2003. Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development. J. Immunol. 170: 325-333. (Pubitemid 36026156)
    • (2003) Journal of Immunology , vol.170 , Issue.1 , pp. 325-333
    • Zhu, M.1    Janssen, E.2    Zhang, W.3
  • 7
    • 0035898379 scopus 로고    scopus 로고
    • Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development
    • Sommers, C. L., R. K. Menon, A. Grinberg, W. Zhang, L. E. Samelson, and P. E. Love. 2001. Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. J. Exp. Med. 194: 135-142.
    • (2001) J. Exp. Med. , vol.194 , pp. 135-142
    • Sommers, C.L.1    Menon, R.K.2    Grinberg, A.3    Zhang, W.4    Samelson, L.E.5    Love, P.E.6
  • 8
    • 0035800805 scopus 로고    scopus 로고
    • Identification of the minimal tyrosine residues required for linker for activation of T cell function
    • Lin, J., and A. Weiss. 2001. Identification of the minimal tyrosine residues required for linker for activation of T cell function. J. Biol. Chem. 276: 29588-29595.
    • (2001) J. Biol. Chem. , vol.276 , pp. 29588-29595
    • Lin, J.1    Weiss, A.2
  • 9
    • 0028245832 scopus 로고
    • A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells
    • Buday, L., S. E. Egan, P. Rodriguez Viciana, D. A. Cantrell, and J. Downward. 1994. A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells. J. Biol. Chem. 269: 9019-9023.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9019-9023
    • Buday, L.1    Egan, S.E.2    Rodriguez Viciana, P.3    Cantrell, D.A.4    Downward, J.5
  • 10
    • 34147203741 scopus 로고    scopus 로고
    • Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes
    • Roose, J. P., M. Mollenauer, M. Ho, T. Kurosaki, and A. Weiss. 2007. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Mol. Cell. Biol. 27: 2732-2745.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2732-2745
    • Roose, J.P.1    Mollenauer, M.2    Ho, M.3    Kurosaki, T.4    Weiss, A.5
  • 11
    • 0029975479 scopus 로고    scopus 로고
    • Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation
    • Jayaraman, T., K. Ondrias, E. Ondriasova, and A. R. Marks. 1996. Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation. Science 272: 1492-1494. (Pubitemid 26200002)
    • (1996) Science , vol.272 , Issue.5267 , pp. 1492-1494
    • Jayaraman, T.1    Ondrias, K.2    Ondriasova, E.3    Marks, A.R.4
  • 12
    • 0027422088 scopus 로고
    • The signal for capacitative calcium entry
    • Putney, J. W., Jr., and G. S. Bird. 1993. The signal for capacitative calcium entry. Cell 75: 199-201.
    • (1993) Cell , vol.75 , pp. 199-201
    • Putney Jr., J.W.1    Bird, G.S.2
  • 13
    • 57849148942 scopus 로고    scopus 로고
    • Calcium signaling in immune cells
    • Vig, M., and J. P. Kinet. 2009. Calcium signaling in immune cells. Nat. Immunol. 10: 21-27.
    • (2009) Nat. Immunol. , vol.10 , pp. 21-27
    • Vig, M.1    Kinet, J.P.2
  • 15
    • 0029556011 scopus 로고
    • Control of T-cell development by the pre-T and αβ T-cell receptor
    • Von Boehmer, H. 1995. Control of T-cell development by the pre-T and αβ T-cell receptor. Ann. N. Y. Acad. Sci. 766: 52-61.
    • (1995) Ann. N. Y. Acad. Sci. , vol.766 , pp. 52-61
    • Von Boehmer, H.1
  • 17
    • 64849091388 scopus 로고    scopus 로고
    • STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells
    • Archambaud, C., A. Sansoni, M. Mingueneau, E. Devilard, G. Delsol, B. Malissen, and M. Malissen. 2009. STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells. J. Immunol. 182: 2680-2689.
    • (2009) J. Immunol. , vol.182 , pp. 2680-2689
    • Archambaud, C.1    Sansoni, A.2    Mingueneau, M.3    Devilard, E.4    Delsol, G.5    Malissen, B.6    Malissen, M.7
  • 19
    • 31344480633 scopus 로고    scopus 로고
    • LAT-mediated signaling in CD4+CD25+ regulatory T cell development
    • Koonpaew, S., S. Shen, L. Flowers, and W. Zhang. 2006. LAT-mediated signaling in CD4+CD25+ regulatory T cell development. J. Exp. Med. 203: 119-129.
    • (2006) J. Exp. Med. , vol.203 , pp. 119-129
    • Koonpaew, S.1    Shen, S.2    Flowers, L.3    Zhang, W.4
  • 20
    • 40749113582 scopus 로고    scopus 로고
    • Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells
    • Wang, Y., A. Kissenpfennig, M. Mingueneau, S. Richelme, P. Perrin, S. Chevrier, C. Genton, B. Lucas, J. P. DiSanto, H. Acha-Orbea, et al. 2008. Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells. J. Immunol. 180: 1565-1575.
    • (2008) J. Immunol. , vol.180 , pp. 1565-1575
    • Wang, Y.1    Kissenpfennig, A.2    Mingueneau, M.3    Richelme, S.4    Perrin, P.5    Chevrier, S.6    Genton, C.7    Lucas, B.8    DiSanto, J.P.9    Acha-Orbea, H.10
  • 21
    • 66949162691 scopus 로고    scopus 로고
    • The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage
    • Shen, S., M. Zhu, J. Lau, M. Chuck, and W. Zhang. 2009. The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage. J. Immunol. 182: 5596-5604.
    • (2009) J. Immunol. , vol.182 , pp. 5596-5604
    • Shen, S.1    Zhu, M.2    Lau, J.3    Chuck, M.4    Zhang, W.5
  • 22
    • 28544444025 scopus 로고    scopus 로고
    • Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow
    • Shapiro-Shelef, M., K. I. Lin, D. Savitsky, J. Liao, and K. Calame. 2005. Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow. J. Exp. Med. 202: 1471-1476.
    • (2005) J. Exp. Med. , vol.202 , pp. 1471-1476
    • Shapiro-Shelef, M.1    Lin, K.I.2    Savitsky, D.3    Liao, J.4    Calame, K.5
  • 25
    • 18944383647 scopus 로고    scopus 로고
    • A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells
    • Roose, J. P., M. Mollenauer, V. A. Gupta, J. Stone, and A. Weiss. 2005. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol. Cell. Biol. 25: 4426-4441.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 4426-4441
    • Roose, J.P.1    Mollenauer, M.2    Gupta, V.A.3    Stone, J.4    Weiss, A.5
  • 26
    • 0030156250 scopus 로고    scopus 로고
    • Intracellular signalling: Putting JAKs on the kinase MAP
    • Winston, L. A., and T. Hunter. 1996. Intracellular signalling: putting JAKs on the kinase MAP. Curr. Biol. 6: 668-671.
    • (1996) Curr. Biol. , vol.6 , pp. 668-671
    • Winston, L.A.1    Hunter, T.2
  • 27
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri, R., T. Cox, S. A. Yasayko, and F. Ramsdell. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4: 337-342.
    • (2003) Nat. Immunol. , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 28
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi, T., Y. Kuniyasu, M. Toda, N. Sakaguchi, M. Itoh, M. Iwata, J. Shimizu, and S. Sakaguchi. 1998. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10: 1969-1980.
    • (1998) Int. Immunol. , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6    Shimizu, J.7    Sakaguchi, S.8
  • 29
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton, A. M., and E. M. Shevach. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188: 287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 30
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid, Y., C. A. Piccirillo, S. Mendez, E. M. Shevach, and D. L. Sacks. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420: 502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 31
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., S. Mauze, M. W. Leach, R. L. Coffman, and F. Powrie. 1999. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190: 995-1004.
    • (1999) J. Exp. Med. , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 32
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy, K. J., L. Salaun, R. Cahill, G. Dougan, N. J. Saunders, and F. Powrie. 2003. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197: 111-119.
    • (2003) J. Exp. Med. , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6
  • 34
    • 34248592104 scopus 로고    scopus 로고
    • T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- And Th17-cell differentiation
    • Li, M. O., Y. Y. Wan, and R. A. Flavell. 2007. T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 26: 579-591.
    • (2007) Immunity , vol.26 , pp. 579-591
    • Li, M.O.1    Wan, Y.Y.2    Flavell, R.A.3
  • 35
    • 0141796312 scopus 로고    scopus 로고
    • TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • Belghith, M., J. A. Bluestone, S. Barriot, J. Mégret, J. F. Bach, and L. Chatenoud. 2003. TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat. Med. 9: 1202-1208.
    • (2003) Nat. Med. , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Mégret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 36
    • 27144486144 scopus 로고    scopus 로고
    • Suppression of allergic airway inflammation by helminth-induced regulatory T cells
    • Wilson, M. S., M. D. Taylor, A. Balic, C. A. Finney, J. R. Lamb, and R. M. Maizels. 2005. Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J. Exp. Med. 202: 1199-1212.
    • (2005) J. Exp. Med. , vol.202 , pp. 1199-1212
    • Wilson, M.S.1    Taylor, M.D.2    Balic, A.3    Finney, C.A.4    Lamb, J.R.5    Maizels, R.M.6
  • 38
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • Piccirillo, C. A., J. J. Letterio, A. M. Thornton, R. S. McHugh, M. Mamura, H. Mizuhara, and E. M. Shevach. 2002. CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J. Exp. Med. 196: 237-246.
    • (2002) J. Exp. Med. , vol.196 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5    Mizuhara, H.6    Shevach, E.M.7
  • 39
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: A jack of all trades, master of regulation
    • Tang, Q., and J. A. Bluestone. 2008. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 9: 239-244.
    • (2008) Nat. Immunol. , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 41
    • 36248976097 scopus 로고    scopus 로고
    • CD4 +CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • Pandiyan, P., L. Zheng, S. Ishihara, J. Reed, and M. J. Lenardo. 2007. CD4 +CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat. Immunol. 8: 1353-1362.
    • (2007) Nat. Immunol. , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 42
    • 0034077559 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
    • Cederbom, L., H. Hall, and F. Ivars. 2000. CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur. J. Immunol. 30: 1538-1543.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 43
    • 33646578505 scopus 로고    scopus 로고
    • + regulatory T-cell-mediated suppression
    • DOI 10.1111/j.1365-2567.2006.02362.x
    • Oderup, C., L. Cederbom, A. Makowska, C. M. Cilio, and F. Ivars. 2006. Cytotoxic T lymphocyte antigen-4-dependent down-modulation of costimulatory molecules on dendritic cells in CD4+ CD25+ regulatory T-cell-mediated suppression. Immunology 118: 240-249. (Pubitemid 43727429)
    • (2006) Immunology , vol.118 , Issue.2 , pp. 240-249
    • Oderup, C.1    Cederbom, L.2    Makowska, A.3    Cilio, C.M.4    Ivars, F.5


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