The androgen metabolite, 5α-androstane-3β,17β-diol, decreases cytokine-induced cyclooxygenase-2, vascular cell adhesion molecule-1 expression, and P-glycoprotein expression in male human brain microvascular endothelial cells

Endocrinology

Volumn 153, Issue 12, 2012, Pages 5949-5960

  Zuloaga, Kristen L ^a   Swift, Sibyl N ^b   Gonzales, Rayna J ^a   Wu, T John ^b   Handa, Robert J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA ANDROSTANEDIOL; ANDROSTANOLONE; CYCLOOXYGENASE 2; FULVESTRANT; INTERLEUKIN 1BETA; MULTIDRUG RESISTANCE PROTEIN; STEROID RECEPTOR; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CONTROLLED STUDY; HORMONE ACTION; HUMAN; HUMAN CELL; MICROVASCULAR ENDOTHELIAL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROID METABOLISM; UPREGULATION;

ANDROSTANE-3,17-DIOL; BLOOD-BRAIN BARRIER; BRAIN; CELLS, CULTURED; CYCLOOXYGENASE 2; DIHYDROTESTOSTERONE; ESTROGEN RECEPTOR BETA; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MALE; P-GLYCOPROTEIN; RNA, MESSENGER; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84870175938     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2012-1316     Document Type: Article

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