Inhibition of NFκM activity through maintenance of IκBα levels contributes to dihydrotestosterone-mediated repression of the interleukin-6 promoter

Journal of Biological Chemistry

Volumn 271, Issue 42, 1996, Pages 26267-26275

  Keller, Evan T ^a   Chang, Chawnshang ^b   Ershler, William B ^b  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANKYRIN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; NUCLEAR FACTOR I; DNA BINDING PROTEIN; I KAPPA B; MESSENGER RNA; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ARTICLE; BONE METABOLISM; CANCER CELL CULTURE; CONTROLLED STUDY; DNA FOOTPRINTING; ELECTROPHORETIC MOBILITY; GENE REPRESSION; HORMONE RESPONSIVE ELEMENT; HUMAN; HUMAN CELL; ORCHIECTOMY; OSTEOCLAST; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CARCINOMA; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HELA CELL; MALE; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROSTATE TUMOR;

CELL LINE; DIHYDROTESTOSTERONE; DNA FOOTPRINTING; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-6; MALE; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0029662224     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.42.26267     Document Type: Article

References (87)

1. Keller, E. T., Ershler, W. B., and Chang, C. (1996) Front. Biosci. 1, 59-69
2. Lindzey, J., Kumar, M. V., Grossman, M., Young, C., and Tindall, D. J. (1994) Vitam. Harm. 49, 383-432
3. Leppa, S., Härkönen, P., and Jaikanen, M. (1991) Cell Regul. 2, 1-11
4. Bodine, P. V., Riggs, B. L., and Speisberg, T. C. (1995) J. Steroid Kochern. Mol. Biol. 52, 149-158
5. Bingaman, E. W., Magnuson, D. J., Gray, T. S , and Handa, R. J. (1994) Neuroendocrinology 59, 228-234
6. Clay, C. M., Keri, R. A., Finicle, A. B., Heckert, L. L., Hamernik, D. L., Marschke, K. M., Wilson, E. M., French, F. S., and Nilson, J. H. (1993) J. Biol. Chem. 268, 13556-13564
7. Mizokami, A., Saiga, H., Matsui, T., Mita, T., and Sugita, A. (1992) Endocrinol. Jpn. 39, 235-243
8. Mancini, M. A., Chatterjee, B., and Roy, A. K. (1991) J. Histochem. Cytochem. 39, 401-405
9. Persson, H., Lievre, C.-L., Söder, O., Villar, M. J., Metsis, M., Olson, L., Ritzen, M., and Hökfelt, T. (1990) Science 247, 704-707
10. Metsis, M., Timmusk, T., Alikmets, R., Saarma, M., and Persson, H. (1992) Gene (Amst.) 121, 247-254
11. Kallio, P. J., Poukka, H., Moilanen, A., Jänne, O. A., and Palvimo, J. J. (1995) Mol. Endocrinol. 9, 1017-1028
12. Montpetit, M. L., Lawless, K. R., and Tenniswood, M. (1986) Prostate 8, 25-36
13. Buttyan, R., Zakeri, Z., Lockshin, R., and Wolgemuth, D. (1988) Mol. Endocrinol. 2, 650-657
14. Day, M. L., Wu, S., and Basler, J. W. (1993) Cancer Res. 53, 5597-5599
15. Wolf, D. A., Kohlhuber, F., Schulz, P., Fittler, F., and Eick, D. (1992) Br. J. Cancer. 66, 376-382
16. Wong, P., Pineault, J., Lakins, J., Taillefer, D., Léger, J., Wang, C., and Tenniswood, M. (1993) J. Biol. Chem. 268, 5021-5031
17. Lindzey, J., Grossmann, M., Kumar, M. V., and Tindall, D. J. (1993) Mol. Endocrinol. 7, 1530-1540
18. Quarmby, V. E., Beckman, W. C., Jr., Wilson, E. M., and French, F. S. (1987) Mol. Endocrinol. 1, 865-874
19. Chang, C., Kokontis, J., and Liao, S. (1988) Science 240, 324-326
20. Chang, C., Wang, C., DeLuca, H. F., Ross, T. K., and Shih, C. C.-Y. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5946-5950
21. Chang, C., Saltzman, A., Yeh, S., Young, W., Keller, E., Lee, H., Wang, C., and Mizokami, A. (1995) Crit. Rev. Eukaryotic Gene Trans. 5, 97-125
22. Roche, P. J., Hoare, S. A., and Parker, M. G. (1992) Mol. Endocrinol. 6, 2229-2235
23. Adler, A. J., Scheller, A., and Robins, D. M. (1993) Mol. Cell. Biol. 13, 6326-6335
24. Adler, A. J., Scheller, A., Hoffman. Y., and Robins, D. M. (1991) Mol. Endocrinol. 5, 1587-1596
25. Murtha, P., Tindall, D. J., and Young, C. Y. F. (1993) Biochemistry 32, 6459-6464
26. Rennie, P. S., Bruchovsky, N., Leco, K. J., Sheppard, P. C., McQueen, S. A., Cheng, H., Snoek, R., Hamel, A., Bock, M. E., MacDonald, B. S., Nickel, B. E., Chang, C. Liao, S., Cattini, P. A., and Matusik, R. J. (1993) Mol. Endocrinol. 7, 23-36
27. Cowell, I. G. (1994) Trends Biochem. Sci. 19, 38-42
28. Burcin, M., Kohne, A. C., Runge, D., Steiner, C., and Renkawitz, R. (1994) Semin. Cancer Biol. 5, 337-346
29. Renkawitz, R. (1993) Ann. N. Y. Acad. Sci. 684, 1-10
30. Saatcioglu, F., Ciaret, F. X., and Karin, M. (1994) Semin. Cancer Biol. 5, 347-359
31. Clark, A. R., and Docherty, K. (1993) Biochem. J. 296, 521-541
32. Jackson, M. E. (1991) J. Cell Sci. 100, 1-7
33. Morimoto, R. I. (1992) Curr. Opin. Cell Biol. 4, 480-487
34. Nahoul, K., and Roger, M. (1990) J. Steroid Biochem. 35, 293-299
35. Dabbs, J., Jr. (1990) Chronobiol. Int. 7, 245-249
36. Wishart, J. M.. Need, A. G., Horowitz, M., Morris, H. A., and Nordin, B. E. (1995) Clin. Endocrinol. 42, 141-146
37. Wei, J., Xu, H., Davies, J. L., and Hemmings, G. P. (1992) Life Sci. 51, 1953-1956
38. Bellido, T., Jilka, R. L., Boyce, B. F., Girasole, G., Broxmeyer, H., Dalrymple, S. A., Murray, R., and Manolagas, S. C. (1995) J. Clin. Invest. 95, 2886-2895
39. Zhang, J., Keller, E. T., Pugh, T. D., Stehler, B., and Ershler, W. B. (1996) American Geriatrics Society Annual Meeting, Chicago, p. 128.
40. Ray, A., Sassone-Corsi, P., and Sehgal, P. B. (1989) Mol. Cell. Biol. 9, 5537-5547
41. Santhanam, U., Ray, A., and Sehgal, P. B. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7605-7609
42. Ray, A., Prefontaine, K. E., and Ray, P. (1994) J. Biol. Chem. 269, 12940-12946
43. Pottratz, S. T., Bellido, T., Mocharla, H., Crabb, D., and Manolagas, S. C. (1994) J. Clin. Invest. 93, 944-950
44. Ray, A., LaForge, K. S., and Sehgal, P. B. (1990) Mol. Cell. Biol. 10, 5736-5746
45. Yasukawa, K., Hirano, T., Watanabe, Y., Muratani, K., Matsuda, T., Nakai, S., and Kishimoto, T. (1987) EMBO J. 6, 2939-2945
46. Haskill, S., Beg, A. A., Tompkins, S. M., Morris, J. S., Yurochko, A, D., Sampson-Johanes, A., Mondal, K., Ralph, P., and Baldwin, A. S., Jr. (1991) Cell 65, 1281-1289
47. Keller, E. T, and Ershler, W. B. (1995) J. Immunol. 154, 4091-4098
48. Sambrook. J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
49. Dent, C. L., and Latchman, D. S. (1993) in Transcription Factors: A Practical Approach (Latchman, D. S., ed) 1st Ed., pp. 1-26, Oxford University Press, New York
50. Ray, A., Tatter, S. B., May, L. T., and Sehgal, P. B. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 6701-6705
51. Strahle, U., Klock, G., and Schutz, G. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 7871-7875
52. Pottratz, S. T., Bellido, T., Mocharla, H., Crabb, D., and Manolagas, S. C. (1994) J. Clin. Invest. 93, 944-950
53. Culig, Z., Hobisch, A., Cronauer, M. V., Cato, A. C., Hittmair, A., Radmayr, C., Eberle, J., Bartsch, G., and Klocker, H. (1993) Mol. Endocrinol. 7, 1541-1550
54. Harris, S. E., Hong, Z., Harris, M. A., and Lubahn, D. D. (1990) Endocrinology 126, (suppl.) 93-97
55. Wilding, G., Chen, M., and Gelmann, E. P. (1989) Prostate 14, 103-115
56. Zhang, Y., Broser, M., and Rom, W. N. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2225-2229
57. Galien, R., Evans, H. F., and Garcia, T. (1996) Mol. Endocrinol. 10, 713-722
58. Descheemaeker, K. A., Wyns, S., Nellea, L., Auwerx, J., Ny, T., and Collen, D. (1992) J. Biol. Chem. 267, 15086-15091
59. Auphan, N., SiSonato, A., Rosette, C., Helmberg, A., and Karin, M. (1995) Science 270, 2286-2290
60. Scheinman, R. I., Cogswell, P. C., Lofquist, A. K., and Baldwin, A. S., Jr. (1995) Science 270, 283-286
61. Jilka, R. L., Hangoc, G., Girasole, G., Paaseri, G., Williams, D. C., Abrams, J. S., Boyce, B., Broxmeyer, H., and Manolagas, S. C. (1992) Science 257, 88-91
62. Tabibzadeh, S. S., Santhanam, U., Sehgal, P. B., and May, L. T. (1989) J. Immunol. 142, 3134-3139
63. Ray, A., and Prefontaine, K. E. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 752-756
64. Stein, B., and Yang, M. X. (1995) Mol. Cell. Biol. 15, 4971-4979
65. Levine, M., and Manley, J. L. (1989) Cell 59, 405-408
66. Yen, P. M., and Chin, W. W. (1994) Mol. Endocrinol. 8, 1450-1454
67. Briehl, M. M., and Miesfeld, R. L. (1991) Mol. Endocrinol. 5, 1381-1388
68. Ito, C. Y., Kazantaev, A. G., and Baldwin, A., Jr. ( 1994) Nucleic Acids Res. 22, 3787-3792
69. Le Bail, O., Schmidt-Ullrich, R., and Israel, A. (1993) EMBO J. 12, 5043-5049
70. Verma, I. M., Stevenson, J. K., Schwarz, E. M., Van Antwerp, D., and Miyamoto, S. (1995) Genes Dev. 9, 2723-2735
71. Beg, A. A., and Baldwin, A. S. (1993) Genes Dev. 7, 2064-2070
72. Miyamoto, S., and Verma, I. M. (1995) Adv. Cancer Res 66, 255-292
73. Bauerle, P. A., and Baltimore, D. (1989) Genes Dev. 3, 1689-1698
74. Davis, N., Ghosh, S., Simmons, D. L., Tempst, P., Liou, H.-C., Baltimore, D., and Bose, H. R., Jr. (1991) Science 253, 1268-1271
75. Nolan, G. P., Ghosh, S.. Liou, H. C., Tempst, P., and Baltimore, D. (1991) Cell 64, 961-969
76. Urban, M. B., and Baeuerle, P. A. (1991) New Biol. 3, 279-288
77. Matsusaka, T., Fujikawa, K., Nishio, Y., Mukaida, N., Matsushima, K., Kishimoto, T., and Akira, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10193-10197
78. De Vos, P., Ciaessens, F., Winderickx, J., Van Dijck, F., Celis, L., Peeters, B., Rombauts, W., Heyns, W., and Verhoeven, G. (1991) J. Biol. Chem. 266, 3439-3443
79. Claessens, F., Celis, L., De Vos, P., Peeters, B., Heyns, W., Verhoeven, G., and Rombauts, W. (1993) Biochem. Biophys. Res. Commun. 191, 688-694
80. Ershler, W. B., Sun, W. H., and Binkley, N. (1994) Drugs & Aging 5, 358-365
81. Gumerlock, P. H., Tang, Y. J., Fishman, J. R., Navarro, L., Meyers, F. J., and deVere White, R. W. (1992) Proc. Annu. Meet. Am. Assoc. Cancer Res. 33, A2170
82. Serve, J., Steinhauser, G., Oberberg, D., Fiegel, W. A., Northoff, J., and Berdel, W. E. (1991) Cancer Res. 51, 3862-3866
83. Siegall, C. B., Schwab, G., Nordan, R. P., FitzGerald, D. J., and Pastan, I. (1990) Cancer Res. 50, 7786-7788
84. Gumerlock, P. H., and Li, J. H. (1993) Proc. Anna. Meet. Am. Assoc. Cancer Res. 34, A2950
85. Siegsmund, M. J., Yamazki, H., and Pastan, I. (1994) J. Urol. 151, 1396-1399
86. Twillie, D. A., Eisenberger, M. A., Carducci, M. A., Hseih, W. S., Kim, W. Y., and Simons, J. W. (1995) Urology 45, 542-549
87. Eriksson, S., Eriksson, A., Stege, R., and Carlström, K. (1995) Calcif. Tissue Int. 57, 97-99