-
1
-
-
77949271600
-
Management of breast cancer with targeted agents: Importance of heterogeneity. [corrected]
-
Di Cosimo S, Baselga J. Management of breast cancer with targeted agents: importance of heterogeneity. [corrected]. Nat Rev Clin Oncol 2010; 7(3): 139-147.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, Issue.3
, pp. 139-147
-
-
Di Cosimo, S.1
Baselga, J.2
-
2
-
-
45149094267
-
Basal-like breast cancer: A critical review
-
Rakha EA, Reis-Filho JS, Ellis IO. Basal-like breast cancer: a critical review. J Clin Oncol 2008; 26(15): 2568-2581.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15
, pp. 2568-2581
-
-
Rakha, E.A.1
Reis-Filho, J.S.2
Ellis, I.O.3
-
3
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000; 406(6797): 747-752.
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
4
-
-
70849122251
-
Triple-negative breast cancer--current status and future directions
-
Gluz O, Liedtke C, Gottschalk N, Pusztai L, Nitz U, Harbeck N. Triple-negative breast cancer--current status and future directions. Ann Oncol 2009; 20(12): 1913-1927.
-
(2009)
Ann Oncol
, vol.20
, Issue.12
, pp. 1913-1927
-
-
Gluz, O.1
Liedtke, C.2
Gottschalk, N.3
Pusztai, L.4
Nitz, U.5
Harbeck, N.6
-
5
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001; 98(19): 10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
6
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003; 100(14): 8418-8423.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
-
7
-
-
77954216525
-
Triple negative breast cancer: Outcome correlation with immunohistochemical detection of basal markers
-
Thike AA, Iqbal J, Cheok PY, et al. Triple negative breast cancer: outcome correlation with immunohistochemical detection of basal markers. Am J Surg Pathol 2010; 34(7): 956-964.
-
(2010)
Am J Surg Pathol
, vol.34
, Issue.7
, pp. 956-964
-
-
Thike, A.A.1
Iqbal, J.2
Cheok, P.Y.3
-
8
-
-
55749113703
-
Triple-negative breast cancer
-
Stockmans G, Deraedt K, Wildiers H, Moerman P, Paridaens R. Triple-negative breast cancer. Curr Opin Oncol 2008; 20(6): 614-620.
-
(2008)
Curr Opin Oncol
, vol.20
, Issue.6
, pp. 614-620
-
-
Stockmans, G.1
Deraedt, K.2
Wildiers, H.3
Moerman, P.4
Paridaens, R.5
-
9
-
-
77952978785
-
Through a glass darkly: Advances in understanding breast cancer biology, 2000-2010
-
Carey LA. Through a glass darkly: advances in understanding breast cancer biology, 2000-2010. Clin Breast Cancer 2010; 10(3): 188-195.
-
(2010)
Clin Breast Cancer
, vol.10
, Issue.3
, pp. 188-195
-
-
Carey, L.A.1
-
10
-
-
40949121882
-
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
-
Cheang MC, Voduc D, Bajdik C, et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res 2008; 14(5): 1368-1376.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.5
, pp. 1368-1376
-
-
Cheang, M.C.1
Voduc, D.2
Bajdik, C.3
-
11
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004; 10(16): 5367-5374.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
-
12
-
-
77950357625
-
Identification of basal-like carcinomas in clinical practice: Triple zero/BRCA1-like carcinomas]
-
Vincent-Salomon A, Macgrogan G, Charaffe-Jauffret E, Jacquemier J, Arnould L. Identification of basal-like carcinomas in clinical practice: triple zero/BRCA1-like carcinomas]. Bull Cancer 2010; 97(3): 357-363.
-
(2010)
Bull Cancer
, vol.97
, Issue.3
, pp. 357-363
-
-
Vincent-Salomon, A.1
Macgrogan, G.2
Charaffe-Jauffret, E.3
Jacquemier, J.4
Arnould, L.5
-
13
-
-
77951206427
-
Triple-negative breast cancer: Molecular features, pathogenesis, treatment and current lines of research
-
Bosch A, Eroles P, Zaragoza R, Vina JR, Lluch A. Triple-negative breast cancer: molecular features, pathogenesis, treatment and current lines of research. Cancer Treat Rev 2010; 36(3): 206-215.
-
(2010)
Cancer Treat Rev
, vol.36
, Issue.3
, pp. 206-215
-
-
Bosch, A.1
Eroles, P.2
Zaragoza, R.3
Vina, J.R.4
Lluch, A.5
-
14
-
-
77953028390
-
Health disparities in breast cancer: Biology meets socioeconomic status
-
Dunn BK, Agurs-Collins T, Browne D, Lubet R, Johnson KA. Health disparities in breast cancer: biology meets socioeconomic status. Breast Cancer Res Treat 2010; 121(2): 281-292.
-
(2010)
Breast Cancer Res Treat
, vol.121
, Issue.2
, pp. 281-292
-
-
Dunn, B.K.1
Agurs-Collins, T.2
Browne, D.3
Lubet, R.4
Johnson, K.A.5
-
15
-
-
65249104546
-
Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes
-
Rakha EA, Elsheikh SE, Aleskandarany MA, et al. Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res 2009; 15(7): 2302-2310.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.7
, pp. 2302-2310
-
-
Rakha, E.A.1
Elsheikh, S.E.2
Aleskandarany, M.A.3
-
16
-
-
77149171459
-
Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer
-
Comen EA, Robson M. Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer. Cancer J 2010; 16(1): 48-52.
-
(2010)
Cancer J
, vol.16
, Issue.1
, pp. 48-52
-
-
Comen, E.A.1
Robson, M.2
-
17
-
-
58149359842
-
Triple-negative breast cancer: Risk factors to potential targets
-
Schneider BP, Winer EP, Foulkes WD, et al. Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res 2008; 14(24): 8010-8018.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.24
, pp. 8010-8018
-
-
Schneider, B.P.1
Winer, E.P.2
Foulkes, W.D.3
-
18
-
-
36549004041
-
Gene expression profiling and histopathological characterization of triplenegative/basal-like breast carcinomas
-
Kreike B, van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triplenegative/basal-like breast carcinomas. Breast Cancer Res 2007; 9(5): R65.
-
(2007)
Breast Cancer Res
, vol.9
, Issue.5
-
-
Kreike, B.1
van Kouwenhove, M.2
Horlings, H.3
-
19
-
-
77950308839
-
Breast cancer molecular profiling with single sample predictors: A retrospective analysis
-
Weigelt B, Mackay A, A'Hern R, et al. Breast cancer molecular profiling with single sample predictors: a retrospective analysis. Lancet Oncol 2010; 11(4): 339-349.
-
(2010)
Lancet Oncol
, vol.11
, Issue.4
, pp. 339-349
-
-
Weigelt, B.1
Mackay, A.2
A'Hern, R.3
-
20
-
-
79551624262
-
Beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation
-
Geyer FC, Lacroix-Triki M, Savage K, et al. Beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation. Mod Pathol 2011; 24(2): 209-231.
-
(2011)
Mod Pathol
, vol.24
, Issue.2
, pp. 209-231
-
-
Geyer, F.C.1
Lacroix-Triki, M.2
Savage, K.3
-
21
-
-
71049148231
-
Population differences in breast cancer: Survey in indigenous African women reveals overrepresentation of triple-negative breast cancer
-
Huo D, Ikpatt F, Khramtsov A, et al. Population differences in breast cancer: survey in indigenous African women reveals overrepresentation of triple-negative breast cancer. J Clin Oncol 2009;27(27): 4515-4521.
-
(2009)
J Clin Oncol
, vol.27
, Issue.27
, pp. 4515-4521
-
-
Huo, D.1
Ikpatt, F.2
Khramtsov, A.3
-
22
-
-
34247569300
-
Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: A populationbased study from the California cancer Registry
-
Bauer KR, Brown M, Cress RD, Parise CA, Caggiano V. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a populationbased study from the California cancer Registry. Cancer 2007; 109(9): 1721-1728.
-
(2007)
Cancer
, vol.109
, Issue.9
, pp. 1721-1728
-
-
Bauer, K.R.1
Brown, M.2
Cress, R.D.3
Parise, C.A.4
Caggiano, V.5
-
23
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006; 295(21): 2492-2502.
-
(2006)
JAMA
, vol.295
, Issue.21
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
-
24
-
-
70449645182
-
T1N0 triple negative breast cancer: Risk of recurrence and adjuvant chemotherapy
-
Kaplan HG, Malmgren JA, Atwood M. T1N0 triple negative breast cancer: risk of recurrence and adjuvant chemotherapy. Breast J 2009; 15(5): 454-460.
-
(2009)
Breast J
, vol.15
, Issue.5
, pp. 454-460
-
-
Kaplan, H.G.1
Malmgren, J.A.2
Atwood, M.3
-
26
-
-
33745660509
-
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
-
Fulford LG, Easton DF, Reis-Filho JS, et al. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology 2006; 49(1): 22-34.
-
(2006)
Histopathology
, vol.49
, Issue.1
, pp. 22-34
-
-
Fulford, L.G.1
Easton, D.F.2
Reis-Filho, J.S.3
-
27
-
-
30944450821
-
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
-
Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol 2006; 19(2): 264-271.
-
(2006)
Mod Pathol
, vol.19
, Issue.2
, pp. 264-271
-
-
Livasy, C.A.1
Karaca, G.2
Nanda, R.3
-
28
-
-
76749131688
-
Triple-negative/basal-like breast cancer: Clinical, pathologic and molecular features
-
Venkitaraman R. Triple-negative/basal-like breast cancer: clinical, pathologic and molecular features. Expert Rev Anticancer Ther 2010; 10(2): 199-207.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, Issue.2
, pp. 199-207
-
-
Venkitaraman, R.1
-
29
-
-
34547661993
-
Triple-negative breast cancer: Clinical features and patterns of recurrence
-
Dent R, Trudeau M, Pritchard KI, et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 2007; 13(15 Pt 1): 4429-4434.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.15 Pt 1
, pp. 4429-4434
-
-
Dent, R.1
Trudeau, M.2
Pritchard, K.I.3
-
30
-
-
77951118432
-
Cancer: Genomics of metastasis
-
Gray J. Cancer: Genomics of metastasis. Nature 2010; 464(7291): 989-990.
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 989-990
-
-
Gray, J.1
-
31
-
-
70350008453
-
Triple-negative and HER2- overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases
-
Heitz F, Harter P, Lueck HJ, et al. Triple-negative and HER2- overexpressing breast cancers exhibit an elevated risk and an earlier occurrence of cerebral metastases. Eur J Cancer 2009; 45(16): 2792-2798.
-
(2009)
Eur J Cancer
, vol.45
, Issue.16
, pp. 2792-2798
-
-
Heitz, F.1
Harter, P.2
Lueck, H.J.3
-
32
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 2008; 26(8): 1275-1281.
-
(2008)
J Clin Oncol
, vol.26
, Issue.8
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
-
33
-
-
44849114353
-
Subtypes of breast cancer show preferential site of relapse
-
Smid M, Wang Y, Zhang Y, et al. Subtypes of breast cancer show preferential site of relapse. Cancer Res 2008; 68(9): 3108-3114.
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3108-3114
-
-
Smid, M.1
Wang, Y.2
Zhang, Y.3
-
34
-
-
77955709404
-
Management of triple negative breast cancer
-
Oakman C, Viale G, Di Leo A. Management of triple negative breast cancer. Breast 2010; 19(5): 312-321.
-
(2010)
Breast
, vol.19
, Issue.5
, pp. 312-321
-
-
Oakman, C.1
Viale, G.2
Di Leo, A.3
-
35
-
-
21044455192
-
Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer
-
Gusterson BA, Ross DT, Heath VJ, Stein T. Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer. Breast Cancer Res 2005; 7(4): 143-148.
-
(2005)
Breast Cancer Res
, vol.7
, Issue.4
, pp. 143-148
-
-
Gusterson, B.A.1
Ross, D.T.2
Heath, V.J.3
Stein, T.4
-
36
-
-
37349018961
-
Triple negative breast carcinoma and the basal phenotype: From expression profiling to clinical practice
-
Diaz LK, Cryns VL, Symmans WF, Sneige N. Triple negative breast carcinoma and the basal phenotype: from expression profiling to clinical practice. Adv Anat Pathol 2007; 14(6): 419-430.
-
(2007)
Adv Anat Pathol
, vol.14
, Issue.6
, pp. 419-430
-
-
Diaz, L.K.1
Cryns, V.L.2
Symmans, W.F.3
Sneige, N.4
-
37
-
-
77955443486
-
Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers
-
Witkiewicz AK, Dasgupta A, Sammons S, et al. Loss of stromal caveolin-1 expression predicts poor clinical outcome in triple negative and basal-like breast cancers. Cancer Biol Ther 2010; 10(2): 135-143.
-
(2010)
Cancer Biol Ther
, vol.10
, Issue.2
, pp. 135-143
-
-
Witkiewicz, A.K.1
Dasgupta, A.2
Sammons, S.3
-
38
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010; 464(7291): 999-1005.
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
-
39
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J, King MC. Genetic heterogeneity in human disease. Cell 2010; 141(2): 210-217.
-
(2010)
Cell
, vol.141
, Issue.2
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
40
-
-
0037685164
-
Breast and ovarian cancer
-
Wooster R, Weber BL. Breast and ovarian cancer. N Engl J Med 2003; 348(23): 2339-2347.
-
(2003)
N Engl J Med
, vol.348
, Issue.23
, pp. 2339-2347
-
-
Wooster, R.1
Weber, B.L.2
-
41
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
Turner NC, Reis-Filho JS, Russell AM, et al. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2007; 26(14): 2126-2132.
-
(2007)
Oncogene
, vol.26
, Issue.14
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
-
42
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner N, Tutt A, Ashworth A. Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 2004; 4(10): 814-819.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.10
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
43
-
-
79952716583
-
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
-
Sproul D, Nestor C, Culley J, et al. Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proc Natl Acad Sci USA 2011; 108(11): 4364-4369.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.11
, pp. 4364-4369
-
-
Sproul, D.1
Nestor, C.2
Culley, J.3
-
44
-
-
70449534798
-
Methylation not a frequent second hit in tumors with germline BRCA mutations
-
Dworkin AM, Spearman AD, Tseng SY, Sweet K, Toland AE. Methylation not a frequent second hit in tumors with germline BRCA mutations. Fam Cancer 2009; 8(4): 339-346.
-
(2009)
Fam Cancer
, vol.8
, Issue.4
, pp. 339-346
-
-
Dworkin, A.M.1
Spearman, A.D.2
Tseng, S.Y.3
Sweet, K.4
Toland, A.E.5
-
45
-
-
0034307160
-
BRCA1 promoter region hypermethylation in ovarian carcinoma: A population-based study
-
Baldwin RL, Nemeth E, Tran H, et al. BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study. Cancer Res 2000; 60(19): 5329-5333.
-
(2000)
Cancer Res
, vol.60
, Issue.19
, pp. 5329-5333
-
-
Baldwin, R.L.1
Nemeth, E.2
Tran, H.3
-
46
-
-
0033580432
-
Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: Correlation with disease characteristics
-
Catteau A, Harris WH, Xu CF, Solomon E. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics. Oncogene 1999; 18(11): 1957-1965.
-
(1999)
Oncogene
, vol.18
, Issue.11
, pp. 1957-1965
-
-
Catteau, A.1
Harris, W.H.2
Xu, C.F.3
Solomon, E.4
-
47
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000; 92(7): 564-569.
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.7
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
48
-
-
0033857349
-
Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens
-
Rice JC, Ozcelik H, Maxeiner P, Andrulis I, Futscher BW. Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens. Carcinogenesis 2000; 21(9): 1761-1765.
-
(2000)
Carcinogenesis
, vol.21
, Issue.9
, pp. 1761-1765
-
-
Rice, J.C.1
Ozcelik, H.2
Maxeiner, P.3
Andrulis, I.4
Futscher, B.W.5
-
49
-
-
0029894211
-
Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer
-
Beckmann MW, Picard F, An HX, et al. Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer. Br J Cancer 1996; 73(10): 1220-1226.
-
(1996)
Br J Cancer
, vol.73
, Issue.10
, pp. 1220-1226
-
-
Beckmann, M.W.1
Picard, F.2
An, H.X.3
-
50
-
-
0142059657
-
Pooled analysis of loss of heterozygosity in breast cancer: A genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions
-
Miller BJ, Wang D, Krahe R, Wright FA. Pooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions. Am J Hum Genet 2003; 73(4): 748-767.
-
(2003)
Am J Hum Genet
, vol.73
, Issue.4
, pp. 748-767
-
-
Miller, B.J.1
Wang, D.2
Krahe, R.3
Wright, F.A.4
-
51
-
-
0042941431
-
Haplo-insufficiency of BRCA1 in sporadic breast cancer
-
Staff S, Isola J, Tanner M. Haplo-insufficiency of BRCA1 in sporadic breast cancer. Cancer Res 2003; 63(16): 4978-4983.
-
(2003)
Cancer Res
, vol.63
, Issue.16
, pp. 4978-4983
-
-
Staff, S.1
Isola, J.2
Tanner, M.3
-
52
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
Meindl A, Hellebrand H, Wiek C, Erven V, Wappenschmidt B, Niederacher D, et al. Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet 2010; 42(5): 410-414.
-
(2010)
Nat Genet
, vol.42
, Issue.5
, pp. 410-414
-
-
Meindl, A.1
Hellebrand, H.2
Wiek, C.3
Erven, V.4
Wappenschmidt, B.5
Niederacher, D.6
-
53
-
-
0038415852
-
A growing network of cancer-susceptibility genes
-
Venkitaraman AR. A growing network of cancer-susceptibility genes. N Engl J Med 2003; 348(19): 1917-1919.
-
(2003)
N Engl J Med
, vol.348
, Issue.19
, pp. 1917-1919
-
-
Venkitaraman, A.R.1
-
54
-
-
1342301467
-
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: Implications for treatment and survival
-
Marsit CJ, Liu M, Nelson HH, Posner M, Suzuki M, Kelsey KT. Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene 2004; 23(4): 1000-1004.
-
(2004)
Oncogene
, vol.23
, Issue.4
, pp. 1000-1004
-
-
Marsit, C.J.1
Liu, M.2
Nelson, H.H.3
Posner, M.4
Suzuki, M.5
Kelsey, K.T.6
-
55
-
-
2342633174
-
Promoter hypermethylation of FANCF: Disruption of Fanconi Anemia-BRCA pathway in cervical cancer
-
Narayan G, Arias-Pulido H, Nandula SV, et al. Promoter hypermethylation of FANCF: disruption of Fanconi Anemia-BRCA pathway in cervical cancer. Cancer Res 2004; 64(9): 2994-2997.
-
(2004)
Cancer Res
, vol.64
, Issue.9
, pp. 2994-2997
-
-
Narayan, G.1
Arias-Pulido, H.2
Nandula, S.V.3
-
56
-
-
1542509662
-
FANCF methylation contributes to chemoselectivity in ovarian cancer
-
Olopade OI, Wei M. FANCF methylation contributes to chemoselectivity in ovarian cancer. Cancer Cell 2003; 3(5): 417-420.
-
(2003)
Cancer Cell
, vol.3
, Issue.5
, pp. 417-420
-
-
Olopade, O.I.1
Wei, M.2
-
57
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003; 9(5): 568-574.
-
(2003)
Nat Med
, vol.9
, Issue.5
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
-
58
-
-
0141429017
-
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer
-
Foulkes WD, Stefansson IM, Chappuis PO, et al. Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst 2003; 95(19): 1482-1485.
-
(2003)
J Natl Cancer Inst
, vol.95
, Issue.19
, pp. 1482-1485
-
-
Foulkes, W.D.1
Stefansson, I.M.2
Chappuis, P.O.3
-
59
-
-
0030818584
-
Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers
-
Collins N, Wooster R, Stratton MR. Absence of methylation of CpG dinucleotides within the promoter of the breast cancer susceptibility gene BRCA2 in normal tissues and in breast and ovarian cancers. Br J Cancer 1997; 76(9): 1150-1156.
-
(1997)
Br J Cancer
, vol.76
, Issue.9
, pp. 1150-1156
-
-
Collins, N.1
Wooster, R.2
Stratton, M.R.3
-
60
-
-
10744233204
-
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Hughes-Davies L, Huntsman D, Ruas M, et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115(5): 523-535.
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
-
61
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
Edwards SL, Brough R, Lord CJ, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature 2008; 451(7182): 1111-1115.
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
-
62
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
Sakai W, Swisher EM, Karlan BY, et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 2008; 451(7182): 1116-1120.
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
-
63
-
-
40749114724
-
The Yin and Yang of treating BRCA-deficient tumors
-
Martin RW, Connell PP, Bishop DK. The Yin and Yang of treating BRCA-deficient tumors. Cell 2008; 132(6): 919-920.
-
(2008)
Cell
, vol.132
, Issue.6
, pp. 919-920
-
-
Martin, R.W.1
Connell, P.P.2
Bishop, D.K.3
-
64
-
-
84870184028
-
Molecular prognostic factors: Clinical implications in patients with breast cancer
-
Giuseppe T, Maria EF, Gaia S. Molecular prognostic factors: clinical implications in patients with breast cancer. Cancer Therapy 2008; 6: 773-782.
-
(2008)
Cancer Therapy
, vol.6
, pp. 773-782
-
-
Giuseppe, T.1
Maria, E.F.2
Gaia, S.3
-
65
-
-
40349100163
-
BRCA1 regulates human mammary stem/progenitor cell fate
-
Liu S, Ginestier C, Charafe-Jauffret E, et al. BRCA1 regulates human mammary stem/progenitor cell fate. Proc Natl Acad Sci USA 2008; 105(5): 1680-1685.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.5
, pp. 1680-1685
-
-
Liu, S.1
Ginestier, C.2
Charafe-Jauffret, E.3
-
66
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008; 8(3): 193-204.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.3
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
67
-
-
33745867638
-
Poly(ADP-ribose): Novel functions for an old molecule
-
Schreiber V, Dantzer F, Ame JC, de Murcia G. Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol 2006; 7(7): 517-528.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.7
, pp. 517-528
-
-
Schreiber, V.1
Dantzer, F.2
Ame, J.C.3
de Murcia, G.4
-
68
-
-
77954274504
-
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
-
Krishnakumar R, Kraus WL. The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets. Mol Cell 2010; 39(1): 8-24.
-
(2010)
Mol Cell
, vol.39
, Issue.1
, pp. 8-24
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
69
-
-
61449162102
-
Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer
-
Arnes JB, Begin LR, Stefansson I, et al. Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer. J Clin Pathol 2009; 62(2): 139-146.
-
(2009)
J Clin Pathol
, vol.62
, Issue.2
, pp. 139-146
-
-
Arnes, J.B.1
Begin, L.R.2
Stefansson, I.3
-
70
-
-
85010791733
-
A combined analysis of outcome following breast cancer: Differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment
-
Robson ME, Chappuis PO, Satagopan J, et al. A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment. Breast Cancer Res 2004; 6(1): R8-R17.
-
(2004)
Breast Cancer Res
, vol.6
, Issue.1
-
-
Robson, M.E.1
Chappuis, P.O.2
Satagopan, J.3
-
71
-
-
0034671417
-
Familial invasive breast cancers: Worse outcome related to BRCA1 mutations
-
Stoppa-Lyonnet D, Ansquer Y, Dreyfus H, et al. Familial invasive breast cancers: worse outcome related to BRCA1 mutations. J Clin Oncol 2000; 18(24): 4053-4059.
-
(2000)
J Clin Oncol
, vol.18
, Issue.24
, pp. 4053-4059
-
-
Stoppa-Lyonnet, D.1
Ansquer, Y.2
Dreyfus, H.3
-
72
-
-
0035931947
-
Gene-expression profiles in hereditary breast cancer
-
Hedenfalk I, Duggan D, Chen Y, et al. Gene-expression profiles in hereditary breast cancer. N Engl J Med 2001; 344(8): 539-548.
-
(2001)
N Engl J Med
, vol.344
, Issue.8
, pp. 539-548
-
-
Hedenfalk, I.1
Duggan, D.2
Chen, Y.3
-
73
-
-
77949908546
-
Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer
-
Silver DP, Richardson AL, Eklund AC, et al. Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer. J Clin Oncol 2010; 28(7): 1145-1153.
-
(2010)
J Clin Oncol
, vol.28
, Issue.7
, pp. 1145-1153
-
-
Silver, D.P.1
Richardson, A.L.2
Eklund, A.C.3
-
74
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, et al. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 2005; 434(7035): 913-917.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
-
75
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434(7035): 917-921.
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
-
76
-
-
52449111109
-
Selective inhibition of BRCA2- deficient mammary tumor cell growth by AZD2281 and cisplatin
-
Evers B, Drost R, Schut E, et al. Selective inhibition of BRCA2- deficient mammary tumor cell growth by AZD2281 and cisplatin. Clin Cancer Res 2008; 14(12): 3916-3925.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.12
, pp. 3916-3925
-
-
Evers, B.1
Drost, R.2
Schut, E.3
-
77
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009; 361(2): 123-134.
-
(2009)
N Engl J Med
, vol.361
, Issue.2
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
-
78
-
-
65949095892
-
Poly(ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous Brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin
-
Hay T, Matthews JR, Pietzka L, et al. Poly(ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous Brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin. Cancer Res 2009; 69(9): 3850-3855.
-
(2009)
Cancer Res
, vol.69
, Issue.9
, pp. 3850-3855
-
-
Hay, T.1
Matthews, J.R.2
Pietzka, L.3
-
79
-
-
42749092016
-
Modeling therapy resistance in genetically engineered mouse cancer models
-
Rottenberg S, Jonkers J. Modeling therapy resistance in genetically engineered mouse cancer models. Drug Resist Updat 2008; 11(1/2): 51-60.
-
(2008)
Drug Resist Updat
, vol.11
, Issue.1-2
, pp. 51-60
-
-
Rottenberg, S.1
Jonkers, J.2
-
80
-
-
49249119415
-
A synthetic lethal therapeutic approach: Poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair
-
Ashworth A. A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol 2008; 26(22): 3785-3790.
-
(2008)
J Clin Oncol
, vol.26
, Issue.22
, pp. 3785-3790
-
-
Ashworth, A.1
-
81
-
-
77449113489
-
Development of 'synthetic lethal' strategies to target BRCA1-deficient breast cancer
-
Wicha MS. Development of 'synthetic lethal' strategies to target BRCA1-deficient breast cancer. Breast Cancer Res 2009; 11(5): 108.
-
(2009)
Breast Cancer Res
, vol.11
, Issue.5
, pp. 108
-
-
Wicha, M.S.1
-
82
-
-
77957599220
-
Poly(ADP-Ribose) polymerase inhibition: Targeted therapy for triple-negative breast cancer
-
Anders CK, Winer EP, Ford JM, et al. Poly(ADP-Ribose) polymerase inhibition: targeted therapy for triple-negative breast cancer. Clin Cancer Res 2010; 16(19): 4702-4710.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.19
, pp. 4702-4710
-
-
Anders, C.K.1
Winer, E.P.2
Ford, J.M.3
-
83
-
-
77956169136
-
Targeting DNA repair in breast cancer: A clinical and translational update
-
Amir E, Seruga B, Serrano R, Ocana A. Targeting DNA repair in breast cancer: A clinical and translational update. Cancer Treat Rev 2010.
-
(2010)
Cancer Treat Rev
-
-
Amir, E.1
Seruga, B.2
Serrano, R.3
Ocana, A.4
-
85
-
-
79955731161
-
Iniparib in metastatic triplenegative breast cancer
-
author reply 1
-
Domagala P, Lubinski J, Domagala W. Iniparib in metastatic triplenegative breast cancer. N Engl J Med 2011; 364(18): 1780; author reply 1.
-
(2011)
N Engl J Med
, vol.364
, Issue.18
, pp. 1780
-
-
Domagala, P.1
Lubinski, J.2
Domagala, W.3
-
86
-
-
77954438677
-
Novel treatment approaches for triple-negative breast cancer
-
Telli ML, Ford JM. Novel treatment approaches for triple-negative breast cancer. Clin Breast Cancer 2010; 10: E16-E22.
-
(2010)
Clin Breast Cancer
, vol.10
-
-
Telli, M.L.1
Ford, J.M.2
-
87
-
-
79952109500
-
PARP-1 inhibitors: A novel genetically specific agents for cancer therapy
-
Cipak L, Jantova S. PARP-1 inhibitors: a novel genetically specific agents for cancer therapy. Neoplasma 2010; 57(5): 401-405.
-
(2010)
Neoplasma
, vol.57
, Issue.5
, pp. 401-405
-
-
Cipak, L.1
Jantova, S.2
-
88
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 2010; 376(9737): 235-244.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
-
89
-
-
68149161777
-
Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer
-
Tutt A, Robson M, Garber J, et al. Phase II trial of the oral PARP inhibitor olaparib in BRCA-deficient advanced breast cancer. J Clin Oncol (Meet Abstr) 2009; 27: CRA501.
-
(2009)
J Clin Oncol (Meet Abstr)
, vol.27
-
-
Tutt, A.1
Robson, M.2
Garber, J.3
-
90
-
-
84871327853
-
-
ASCO Meet Abstr
-
O'Shaughnessy J, Osborne C, Pippen J, et al. Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): results of a randomized phase II trial. ASCO Meet Abstr 2009; 273.
-
(2009)
Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial
, pp. 273
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.3
-
91
-
-
37248999372
-
Triple negative tumours: A critical review
-
Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathology 2008; 52(1): 108-118.
-
(2008)
Histopathology
, vol.52
, Issue.1
, pp. 108-118
-
-
Reis-Filho, J.S.1
Tutt, A.N.2
-
92
-
-
44649095619
-
Expression of BRCA1 protein in breast cancer and its prognostic significance
-
Rakha EA, El-Sheikh SE, Kandil MA, El-Sayed ME, Green AR, Ellis IO. Expression of BRCA1 protein in breast cancer and its prognostic significance. Hum Pathol 2008; 39(6): 857-865.
-
(2008)
Hum Pathol
, vol.39
, Issue.6
, pp. 857-865
-
-
Rakha, E.A.1
El-Sheikh, S.E.2
Kandil, M.A.3
El-Sayed, M.E.4
Green, A.R.5
Ellis, I.O.6
-
93
-
-
0032953384
-
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas
-
Wilson CA, Ramos L, Villasenor MR, et al. Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas Nat Genet 1999; 21(2): 236-240.
-
(1999)
Nat Genet
, vol.21
, Issue.2
, pp. 236-240
-
-
Wilson, C.A.1
Ramos, L.2
Villasenor, M.R.3
-
94
-
-
69449090092
-
Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies
-
Willers H, Taghian AG, Luo CM, Treszezamsky A, Sgroi DC, Powell SN. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol Cancer Res 2009; 7(8): 1304-1309.
-
(2009)
Mol Cancer Res
, vol.7
, Issue.8
, pp. 1304-1309
-
-
Willers, H.1
Taghian, A.G.2
Luo, C.M.3
Treszezamsky, A.4
Sgroi, D.C.5
Powell, S.N.6
-
95
-
-
0040984333
-
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
-
de Murcia JM, Niedergang C, Trucco C, et al. Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci USA 1997; 94(14): 7303-7307.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.14
, pp. 7303-7307
-
-
de Murcia, J.M.1
Niedergang, C.2
Trucco, C.3
-
96
-
-
77954374334
-
Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination-Defective Cells
-
Gottipati P, Vischioni B, Schultz N, et al. Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination-Defective Cells. Cancer Res 2010; 70(13): 5389-5398.
-
(2010)
Cancer Res
, vol.70
, Issue.13
, pp. 5389-5398
-
-
Gottipati, P.1
Vischioni, B.2
Schultz, N.3
-
97
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
Siddik ZH. Cisplatin: mode of cytotoxic action and molecular basis of resistance. Oncogene 2003; 22(47): 7265-7279.
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
98
-
-
77954215461
-
Fine tuning chemotherapy to match BRCA1 status
-
Price M, Monteiro AN. Fine tuning chemotherapy to match BRCA1 status. Biochem Pharmacol 2010; 80(5): 647-653.
-
(2010)
Biochem Pharmacol
, vol.80
, Issue.5
, pp. 647-653
-
-
Price, M.1
Monteiro, A.N.2
-
99
-
-
55949092708
-
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
-
Rottenberg S, Jaspers JE, Kersbergen A, et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci USA 2008; 105(44): 17079-17084.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.44
, pp. 17079-17084
-
-
Rottenberg, S.1
Jaspers, J.E.2
Kersbergen, A.3
-
100
-
-
84954358647
-
A highthroughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity
-
Lord CJ, McDonald S, Swift S, Turner NC, Ashworth A. A highthroughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity. DNA Repair (Amst) 2008; 7(12): 2010-2019.
-
(2008)
DNA Repair (Amst)
, vol.7
, Issue.12
, pp. 2010-2019
-
-
Lord, C.J.1
McDonald, S.2
Swift, S.3
Turner, N.C.4
Ashworth, A.5
-
101
-
-
43249085571
-
A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor
-
Turner NC, Lord CJ, Iorns E, et al. A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. EMBO J 2008; 27(9): 1368-1377.
-
(2008)
EMBO J
, vol.27
, Issue.9
, pp. 1368-1377
-
-
Turner, N.C.1
Lord, C.J.2
Iorns, E.3
-
102
-
-
77149157867
-
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
-
Mendes-Pereira AM, Martin SA, Brough R, et al. Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO Mol Med 2009; 1(6/7): 315-322.
-
(2009)
EMBO Mol Med
, vol.1
, Issue.6-7
, pp. 315-322
-
-
Mendes-Pereira, A.M.1
Martin, S.A.2
Brough, R.3
-
103
-
-
77953653251
-
Converting cancer mutations into therapeutic opportunities
-
O'Brien T, Stokoe D. Converting cancer mutations into therapeutic opportunities. EMBO Mol Med 2009; 1(6/7): 297-299.
-
(2009)
EMBO Mol Med
, vol.1
, Issue.6-7
, pp. 297-299
-
-
O'Brien, T.1
Stokoe, D.2
-
104
-
-
77954358148
-
PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors
-
McEllin B, Camacho CV, Mukherjee B, et al. PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or Poly(ADP-Ribose) Polymerase Inhibitors. Cancer Res 2010; 70(13): 5457-5464.
-
(2010)
Cancer Res
, vol.70
, Issue.13
, pp. 5457-5464
-
-
McEllin, B.1
Camacho, C.V.2
Mukherjee, B.3
-
105
-
-
37249078187
-
Predictive markers in breast cancer-the future
-
Faratian D, Bartlett J. Predictive markers in breast cancer-the future. Histopathology 2008; 52(1): 91-98.
-
(2008)
Histopathology
, vol.52
, Issue.1
, pp. 91-98
-
-
Faratian, D.1
Bartlett, J.2
-
106
-
-
33847136743
-
Triple-negative breast cancer: Therapeutic options
-
Cleator S, Heller W, Coombes RC. Triple-negative breast cancer: therapeutic options. Lancet Oncol 2007; 8(3): 235-244.
-
(2007)
Lancet Oncol
, vol.8
, Issue.3
, pp. 235-244
-
-
Cleator, S.1
Heller, W.2
Coombes, R.C.3
-
107
-
-
41549153733
-
MAPK overexpression is associated with anthracycline resistance and increased risk for recurrence in patients with triple-negative breast cancer
-
Eralp Y, Derin D, Ozluk Y, et al. MAPK overexpression is associated with anthracycline resistance and increased risk for recurrence in patients with triple-negative breast cancer. Ann Oncol 2008; 19(4): 669-674.
-
(2008)
Ann Oncol
, vol.19
, Issue.4
, pp. 669-674
-
-
Eralp, Y.1
Derin, D.2
Ozluk, Y.3
-
108
-
-
63849329936
-
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
-
Marty B, Maire V, Gravier E, et al. Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells. Breast Cancer Res 2008; 10(6): R101.
-
(2008)
Breast Cancer Res
, vol.10
, Issue.6
-
-
Marty, B.1
Maire, V.2
Gravier, E.3
-
111
-
-
35348981836
-
Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas)
-
Lerma E, Peiro G, Ramon T, et al. Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). Mod Pathol 2007; 20(11): 1200-1207.
-
(2007)
Mod Pathol
, vol.20
, Issue.11
, pp. 1200-1207
-
-
Lerma, E.1
Peiro, G.2
Ramon, T.3
-
112
-
-
37549020704
-
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
-
Saal LH, Gruvberger-Saal SK, Persson C, et al. Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair. Nat Genet 2008; 40(1): 102-107.
-
(2008)
Nat Genet
, vol.40
, Issue.1
, pp. 102-107
-
-
Saal, L.H.1
Gruvberger-Saal, S.K.2
Persson, C.3
-
113
-
-
34250687198
-
Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
-
Saal LH, Johansson P, Holm K, et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proc Natl Acad Sci USA 2007; 104(18): 7564-7569.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.18
, pp. 7564-7569
-
-
Saal, L.H.1
Johansson, P.2
Holm, K.3
-
114
-
-
74049107249
-
PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality
-
Lopez-Knowles E, O'Toole SA, McNeil CM, et al. PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality. Int J Cancer 2010; 126(5): 1121-1231.
-
(2010)
Int J Cancer
, vol.126
, Issue.5
, pp. 1121-1231
-
-
Lopez-Knowles, E.1
O'Toole, S.A.2
McNeil, C.M.3
-
115
-
-
70350244859
-
Estrogen receptor-negative breast cancer: New insights into subclassification and targeting
-
Zhao JJ, Silver DP. Estrogen receptor-negative breast cancer: new insights into subclassification and targeting. Clin Cancer Res 2009; 15(20): 6309-6310.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.20
, pp. 6309-6310
-
-
Zhao, J.J.1
Silver, D.P.2
-
116
-
-
70349680576
-
Possible treatment strategies for triple-negative breast cancer on the basis of molecular characteristics
-
Kurebayashi J. Possible treatment strategies for triple-negative breast cancer on the basis of molecular characteristics. Breast Cancer 2009; 16(4): 275-280.
-
(2009)
Breast Cancer
, vol.16
, Issue.4
, pp. 275-280
-
-
Kurebayashi, J.1
-
117
-
-
21844456072
-
Metaplastic breast carcinomas are negative forHer-2 but frequently express EGFR (Her-1): Potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors?
-
Leibl S, Moinfar F. Metaplastic breast carcinomas are negative forHer-2 but frequently express EGFR (Her-1): potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors? J Clin Pathol 2005; 58(7): 700-704.
-
(2005)
J Clin Pathol
, vol.58
, Issue.7
, pp. 700-704
-
-
Leibl, S.1
Moinfar, F.2
-
118
-
-
58349091262
-
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition
-
Mirzoeva OK, Das D, Heiser LM, et al. Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res 2009; 69(2): 565-572.
-
(2009)
Cancer Res
, vol.69
, Issue.2
, pp. 565-572
-
-
Mirzoeva, O.K.1
Das, D.2
Heiser, L.M.3
-
119
-
-
70349119837
-
Triple negative breast cancers: Clinical and prognostic implications
-
Dawson SJ, Provenzano E, Caldas C. Triple negative breast cancers: clinical and prognostic implications. Eur J Cancer 2009; 45 Suppl 1: 27-40.
-
(2009)
Eur J Cancer
, vol.45
, Issue.SUPPL. 1
, pp. 27-40
-
-
Dawson, S.J.1
Provenzano, E.2
Caldas, C.3
-
120
-
-
33846587923
-
The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies
-
Siziopikou KP, Cobleigh M. The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies. Breast 2007; 16(1): 104-107.
-
(2007)
Breast
, vol.16
, Issue.1
, pp. 104-107
-
-
Siziopikou, K.P.1
Cobleigh, M.2
-
121
-
-
43549102063
-
EGFR inhibition with cetuximab in metastatic triple negative (basallike)breast cancer
-
Carey L, Mayer E, Marcom PK, et al. EGFR inhibition with cetuximab in metastatic triple negative (basallike)breast cancer Breast Cancer Res Treat 2007; 106(Suppl 1): S32.
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.SUPPL. 1
-
-
Carey, L.1
Mayer, E.2
Marcom, P.K.3
-
122
-
-
33747819585
-
Clinicopathologic significance of the basal-like subtype of breast cancer: A comparison with hormone receptor and Her2/neuoverexpressing phenotypes
-
Kim MJ, Ro JY, Ahn SH, Kim HH, Kim SB, Gong G. Clinicopathologic significance of the basal-like subtype of breast cancer: a comparison with hormone receptor and Her2/neuoverexpressing phenotypes. Hum Pathol 2006; 37(9): 1217-1226.
-
(2006)
Hum Pathol
, vol.37
, Issue.9
, pp. 1217-1226
-
-
Kim, M.J.1
Ro, J.Y.2
Ahn, S.H.3
Kim, H.H.4
Kim, S.B.5
Gong, G.6
-
123
-
-
1642494767
-
KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations
-
Simon R, Panussis S, Maurer R, et al. KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations. Clin Cancer Res 2004; 10(1 Pt 1): 178-183.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.1 Pt 1
, pp. 178-183
-
-
Simon, R.1
Panussis, S.2
Maurer, R.3
-
124
-
-
21044450946
-
A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer
-
Modi S, Seidman AD, Dickler M, et al. A phase II trial of imatinib mesylate monotherapy in patients with metastatic breast cancer. Breast Cancer Res Treat 2005; 90(2): 157-163.
-
(2005)
Breast Cancer Res Treat
, vol.90
, Issue.2
, pp. 157-163
-
-
Modi, S.1
Seidman, A.D.2
Dickler, M.3
-
125
-
-
3242727861
-
STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells
-
Roussidis AE, Mitropoulou TN, Theocharis AD, et al. STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells. Anticancer Res 2004; 24(3a): 1445-1447.
-
(2004)
Anticancer Res
, vol.24
, Issue.3 a
, pp. 1445-1447
-
-
Roussidis, A.E.1
Mitropoulou, T.N.2
Theocharis, A.D.3
-
126
-
-
0028233617
-
The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients
-
Railo MJ, von Smitten K, Pekonen F. The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients. Eur J Cancer 1994; 30A(3): 307-311.
-
(1994)
Eur J Cancer
, vol.30 A
, Issue.3
, pp. 307-311
-
-
Railo, M.J.1
von Smitten, K.2
Pekonen, F.3
-
127
-
-
34548018304
-
The insulin-like growth factor 1 receptor in cancer: Old focus, new future
-
Hartog H, Wesseling J, Boezen HM, van der Graaf WT. The insulin-like growth factor 1 receptor in cancer: old focus, new future. Eur J Cancer 2007; 43(13): 1895-1904.
-
(2007)
Eur J Cancer
, vol.43
, Issue.13
, pp. 1895-1904
-
-
Hartog, H.1
Wesseling, J.2
Boezen, H.M.3
van der Graaf, W.T.4
-
128
-
-
0033838566
-
Function of the IGF-I receptor in breast cancer
-
Surmacz E. Function of the IGF-I receptor in breast cancer. J Mammary Gland Biol Neoplasia 2000; 5(1): 95-105.
-
(2000)
J Mammary Gland Biol Neoplasia
, vol.5
, Issue.1
, pp. 95-105
-
-
Surmacz, E.1
-
129
-
-
0033845656
-
Insulin-like growth factor-1 and breast cancer risk in postmenopausal African-American women
-
Agurs-Collins T, Adams-Campbell LL, Kim KS, Cullen KJ. Insulin-like growth factor-1 and breast cancer risk in postmenopausal African-American women. Cancer Detect Prev 2000; 24(3): 199-206.
-
(2000)
Cancer Detect Prev
, vol.24
, Issue.3
, pp. 199-206
-
-
Agurs-Collins, T.1
Adams-Campbell, L.L.2
Kim, K.S.3
Cullen, K.J.4
-
130
-
-
0026641496
-
Can the insulin-like growth factors regulate breast cancer growth?
-
Yee D. Can the insulin-like growth factors regulate breast cancer growth? Breast Cancer Res Treat 1992; 22(1): 3-5.
-
(1992)
Breast Cancer Res Treat
, vol.22
, Issue.1
, pp. 3-5
-
-
Yee, D.1
-
131
-
-
60549108365
-
Igf1r as a therapeutic target in a mouse model of basal-like breast cancer
-
Klinakis A, Szabolcs M, Chen G, Xuan S, Hibshoosh H, Efstratiadis A. Igf1r as a therapeutic target in a mouse model of basal-like breast cancer. Proc Natl Acad Sci USA 2009; 106(7): 2359-2364.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.7
, pp. 2359-2364
-
-
Klinakis, A.1
Szabolcs, M.2
Chen, G.3
Xuan, S.4
Hibshoosh, H.5
Efstratiadis, A.6
-
132
-
-
84871279808
-
-
in This Subtype of Human Breast Cancer, Thirty-Second Annual CTRC-AACR San Antonio Breast Cancer Symposium; San Antonio, TX. Dec 10-13
-
Litzenburger B, Tsimelzon A, Hilsenbeck S, et al. In: High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines Correlates with Sensitivity to IGF-IR Inhibitor BMS-754807 in This Subtype of Human Breast Cancer, Thirty-Second Annual CTRC-AACR San Antonio Breast Cancer Symposium; San Antonio, TX. Dec 10-13, 2009.
-
(2009)
N: High IGF-IR Activity In Triple-Negative Breast Cancer Cell Lines Correlates With Sensitivity to IGF-IR Inhibitor BMS-754807
-
-
Litzenburger, B.1
Tsimelzon, A.2
Hilsenbeck, S.3
-
133
-
-
24744444176
-
Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination
-
Yang S, Chintapalli J, Sodagum L, et al. Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination. Am J Physiol Renal Physiol 2005; 289(5): F1144-F1152.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
, Issue.5
-
-
Yang, S.1
Chintapalli, J.2
Sodagum, L.3
-
134
-
-
84871319713
-
-
The Barnes Report, Nov, 5
-
Barnes J. IGF-1R, after a slow start this new oncology target is picking up momentum. 2007; 1(11), The Barnes Report, Nov, 5. Available from: http://www.imakenews.com/barnesreport/e_article000944565.cfm?x=b11,0,w
-
(2007)
IGF-1R, After a Slow Start This New Oncology Target is Picking Up Momentum
, vol.1
, Issue.11
-
-
Barnes, J.1
-
135
-
-
77953183234
-
Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome
-
Khramtsov AI, Khramtsova GF, Tretiakova M, Huo D, Olopade OI, Goss KH. Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome. Am J Pathol 2010; 176(6): 2911-2920.
-
(2010)
Am J Pathol
, vol.176
, Issue.6
, pp. 2911-2920
-
-
Khramtsov, A.I.1
Khramtsova, G.F.2
Tretiakova, M.3
Huo, D.4
Olopade, O.I.5
Goss, K.H.6
-
137
-
-
84871347458
-
-
AACR Annual meeting; Denver, CO. April 18-22
-
Abramovitz M, Catzavelos C, Li Z, et al., In: Identification of Matrix Metalloproteinase 7 (MMP7) as a Selective Biomarker of the Triple-Negative Breast Cancer Subtype. AACR Annual meeting; Denver, CO. April 18-22, 2009.
-
(2009)
In: Identification of Matrix Metalloproteinase 7 (MMP7) As a Selective Biomarker of the Triple-Negative Breast Cancer Subtype
-
-
Abramovitz, M.1
Catzavelos, C.2
Li, Z.3
-
139
-
-
84870234607
-
-
AACR Annual Meeting, Washington, DC
-
Dey N, Barwick B, Bouzyk M, De P, Leyland-Jones B, In: Role of Wnt-beta-catenin pathway in the control of tumor cell invasion in the triple negative subset of breast cancer, AACR Annual Meeting; Washington, DC 2010.
-
(2010)
In: Role of Wnt-beta-catenin Pathway In the Control of Tumor Cell Invasion In the Triple Negative Subset of Breast Cancer
-
-
Dey, N.1
Barwick, B.2
Bouzyk, M.3
De, P.4
Leyland-Jones, B.5
-
140
-
-
77949743786
-
Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin
-
Li H, Sekine M, Tung N, Avraham HK. Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-catenin. Mol Cancer Res 2010; 8(3): 407-420.
-
(2010)
Mol Cancer Res
, vol.8
, Issue.3
, pp. 407-420
-
-
Li, H.1
Sekine, M.2
Tung, N.3
Avraham, H.K.4
-
141
-
-
48749118203
-
Targeting Src in breast cancer
-
Finn RS. Targeting Src in breast cancer. Ann Oncol 2008; 19(8): 1379-1386.
-
(2008)
Ann Oncol
, vol.19
, Issue.8
, pp. 1379-1386
-
-
Finn, R.S.1
-
142
-
-
34548701082
-
Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/triple-negative breast cancer cell lines growing in vitro
-
Finn RS, Dering J, Ginther C, et al. Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/triple-negative breast cancer cell lines growing in vitro. Breast Cancer Res Treat 2007; 105(3): 319-326.
-
(2007)
Breast Cancer Res Treat
, vol.105
, Issue.3
, pp. 319-326
-
-
Finn, R.S.1
Dering, J.2
Ginther, C.3
-
143
-
-
77950284093
-
LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer
-
Choi YL, Bocanegra M, Kwon MJ, et al. LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. Cancer Res 2010; 70(6): 2296-2306.
-
(2010)
Cancer Res
, vol.70
, Issue.6
, pp. 2296-2306
-
-
Choi, Y.L.1
Bocanegra, M.2
Kwon, M.J.3
-
144
-
-
84871312137
-
-
ClinicalTrials.gov
-
ClinicalTrials.gov. Available at http://www.clinicaltrials.gov.
-
-
-
-
145
-
-
77149173177
-
Triple-negative breast cancer: Role of antiangiogenic agents
-
Greenberg S, Rugo HS. Triple-negative breast cancer: role of antiangiogenic agents. Cancer J 2010; 16(1): 33-38.
-
(2010)
Cancer J
, vol.16
, Issue.1
, pp. 33-38
-
-
Greenberg, S.1
Rugo, H.S.2
-
146
-
-
0141921881
-
Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer
-
Goffin JR, Straume O, Chappuis PO, et al. Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer. Br J Cancer 2003; 89(6): 1031-1034.
-
(2003)
Br J Cancer
, vol.89
, Issue.6
, pp. 1031-1034
-
-
Goffin, J.R.1
Straume, O.2
Chappuis, P.O.3
-
147
-
-
10744223743
-
The prognostic implication of the basal-like (cyclin E high/p27low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer
-
Foulkes WD, Brunet JS, Stefansson IM, et al. The prognostic implication of the basal-like (cyclin E high/p27low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer. Cancer Res 2004; 64(3): 830-835.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 830-835
-
-
Foulkes, W.D.1
Brunet, J.S.2
Stefansson, I.M.3
-
148
-
-
0033588842
-
New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
-
Holash J, Wiegand SJ, Yancopoulos GD. New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 1999; 18(38): 5356-5362.
-
(1999)
Oncogene
, vol.18
, Issue.38
, pp. 5356-5362
-
-
Holash, J.1
Wiegand, S.J.2
Yancopoulos, G.D.3
-
149
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, plateletderived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M, LeJeune S, Scott PA, et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, plateletderived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997; 57(5): 963-969.
-
(1997)
Cancer Res
, vol.57
, Issue.5
, pp. 963-969
-
-
Relf, M.1
Lejeune, S.2
Scott, P.A.3
-
150
-
-
33645551935
-
Vascular endothelial growth factor expression in the basal subtype of breast carcinoma
-
Ribeiro-Silva A, Ribeiro do Vale F, Zucoloto S. Vascular endothelial growth factor expression in the basal subtype of breast carcinoma. Am J Clin Pathol 2006; 125(4): 512-518.
-
(2006)
Am J Clin Pathol
, vol.125
, Issue.4
, pp. 512-518
-
-
Ribeiro-Silva, A.1
do Ribeiro, V.F.2
Zucoloto, S.3
-
151
-
-
51549089009
-
Development of therapeutic approaches to 'triple negative' phenotype breast cancer
-
Shiu KK, Tan DS, Reis-Filho JS. Development of therapeutic approaches to 'triple negative' phenotype breast cancer. Expert Opin Ther Targets 2008; 12(9): 1123-1237.
-
(2008)
Expert Opin Ther Targets
, vol.12
, Issue.9
, pp. 1123-1237
-
-
Shiu, K.K.1
Tan, D.S.2
Reis-Filho, J.S.3
-
152
-
-
77950690403
-
Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term followup
-
Ryden L, Jirstrom K, Haglund M, Stal O, Ferno M. Epidermal growth factor receptor and vascular endothelial growth factor receptor 2 are specific biomarkers in triple-negative breast cancer. Results from a controlled randomized trial with long-term followup. Breast Cancer Res Treat 2010; 120(2): 491-498.
-
(2010)
Breast Cancer Res Treat
, vol.120
, Issue.2
, pp. 491-498
-
-
Ryden, L.1
Jirstrom, K.2
Haglund, M.3
Stal, O.4
Ferno, M.5
-
153
-
-
42949148257
-
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
Burstein HJ, Elias AD, Rugo HS, et al. Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol 2008; 26(11): 1810-1816.
-
(2008)
J Clin Oncol
, vol.26
, Issue.11
, pp. 1810-1816
-
-
Burstein, H.J.1
Elias, A.D.2
Rugo, H.S.3
-
154
-
-
35648973650
-
Angiogenesis as targeted breast cancer therapy
-
Hayes DF, Miller K, Sledge G. Angiogenesis as targeted breast cancer therapy. Breast 2007; 16 Suppl 2: S17-S19.
-
(2007)
Breast
, vol.16
, Issue.SUPPL. 2
-
-
Hayes, D.F.1
Miller, K.2
Sledge, G.3
-
155
-
-
33846880876
-
Biomarkers for monitoring antiangiogenic therapy
-
Bhatt RS, Seth P, Sukhatme VP. Biomarkers for monitoring antiangiogenic therapy. Clin Cancer Res 2007; 13(2 Pt 2): 777s-780s.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.2 Pt 2
-
-
Bhatt, R.S.1
Seth, P.2
Sukhatme, V.P.3
-
156
-
-
0032887340
-
Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry
-
Maniotis AJ, Folberg R, Hess A, et al. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol 1999; 155(3): 739-752.
-
(1999)
Am J Pathol
, vol.155
, Issue.3
, pp. 739-752
-
-
Maniotis, A.J.1
Folberg, R.2
Hess, A.3
-
157
-
-
0032886829
-
Tumor plasticity allows vasculogenic mimicry, a novel form of angiogenic switch. A rose by any other name?
-
Bissell MJ. Tumor plasticity allows vasculogenic mimicry, a novel form of angiogenic switch. A rose by any other name? Am J Pathol 1999; 155(3): 675-679.
-
(1999)
Am J Pathol
, vol.155
, Issue.3
, pp. 675-679
-
-
Bissell, M.J.1
-
158
-
-
0030722076
-
Non-small-cell lung carcinoma tumor growth without morphological evidence of neoangiogenesis
-
Pezzella F, Pastorino U, Tagliabue E, et al. Non-small-cell lung carcinoma tumor growth without morphological evidence of neoangiogenesis. Am J Pathol 1997; 151(5): 1417-1423.
-
(1997)
Am J Pathol
, vol.151
, Issue.5
, pp. 1417-1423
-
-
Pezzella, F.1
Pastorino, U.2
Tagliabue, E.3
-
159
-
-
0033520162
-
New type of blood vessel found in tumors
-
Barinaga M. New type of blood vessel found in tumors. Science 1999; 285(5433): 1475.
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1475
-
-
Barinaga, M.1
-
160
-
-
0035863521
-
Absence of endothelial cells, central necrosis, and fibrosis are associated with aggressive inflammatory breast cancer
-
Shirakawa K, Tsuda H, Heike Y, et al. Absence of endothelial cells, central necrosis, and fibrosis are associated with aggressive inflammatory breast cancer. Cancer Res 2001; 61(2): 445-451.
-
(2001)
Cancer Res
, vol.61
, Issue.2
, pp. 445-451
-
-
Shirakawa, K.1
Tsuda, H.2
Heike, Y.3
-
161
-
-
0037081174
-
Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft
-
Shirakawa K, Kobayashi H, Heike Y, et al. Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res 2002; 62(2): 560-566.
-
(2002)
Cancer Res
, vol.62
, Issue.2
, pp. 560-566
-
-
Shirakawa, K.1
Kobayashi, H.2
Heike, Y.3
-
162
-
-
0037142187
-
Vasculogenic mimicry and pseudo-comedo formation in breast cancer
-
Shirakawa K, Wakasugi H, Heike Y, et al. Vasculogenic mimicry and pseudo-comedo formation in breast cancer. Int J Cancer 2002; 99(6): 821-828.
-
(2002)
Int J Cancer
, vol.99
, Issue.6
, pp. 821-828
-
-
Shirakawa, K.1
Wakasugi, H.2
Heike, Y.3
-
163
-
-
79959503213
-
Triple-negative breast cancer: An unmet medical need
-
Hudis CA, Gianni L. Triple-negative breast cancer: an unmet medical need. Oncologist 2011; 16 Suppl 1: 1-11.
-
(2011)
Oncologist
, vol.16
, Issue.SUPPL. 1
, pp. 1-11
-
-
Hudis, C.A.1
Gianni, L.2
-
164
-
-
79151476662
-
Triple negative breast cancer: Unmet medical needs
-
Pal SK, Childs BH, Pegram M. Triple negative breast cancer: unmet medical needs. Breast Cancer Res Treat 2011; 125(3): 627-636.
-
(2011)
Breast Cancer Res Treat
, vol.125
, Issue.3
, pp. 627-636
-
-
Pal, S.K.1
Childs, B.H.2
Pegram, M.3
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