-
1
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406(6797):747-52
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
2
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001;98(19):10869-74
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
3
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003;100(14):8418-23
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
-
4
-
-
33846266252
-
Prognostic markers in triple-negative breast cancer
-
Rakha EA, El-Sayed ME, Green AR, et al. Prognostic markers in triple-negative breast cancer. Cancer 2007;109(1):25-32
-
(2007)
Cancer
, vol.109
, Issue.1
, pp. 25-32
-
-
Rakha, E.A.1
El-Sayed, M.E.2
Green, A.R.3
-
5
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
-
Carey LA, Dees EC, Sawyer L, et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res 2007;13(8):2329-34
-
(2007)
Clin Cancer Res
, vol.13
, Issue.8
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
-
6
-
-
34547661993
-
Triple-negative breast cancer: Clinical features and patterns of recurrence
-
Dent R, Trudeau M, Pritchard KI, et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 2007;13(15 Pt 1):4429-34
-
(2007)
Clin Cancer Res
, vol.13
, Issue.15 PART 1
, pp. 4429-4434
-
-
Dent, R.1
Trudeau, M.2
Pritchard, K.I.3
-
7
-
-
33745660509
-
Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast
-
Fulford LG, Easton DF, Reis-Filho JS, et al. Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology 2006;49(1):22-34
-
(2006)
Histopathology
, vol.49
, Issue.1
, pp. 22-34
-
-
Fulford, L.G.1
Easton, D.F.2
Reis-Filho, J.S.3
-
8
-
-
30944450821
-
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
-
Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol 2006;19(2):264-71
-
(2006)
Mod Pathol
, vol.19
, Issue.2
, pp. 264-271
-
-
Livasy, C.A.1
Karaca, G.2
Nanda, R.3
-
9
-
-
36549004041
-
-
Kreike B, van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas. Breast Cancer Res 2007;9(5):R65. Published online 2 October 2007, doi:10.1186/bcr1771
-
Kreike B, van Kouwenhove M, Horlings H, et al. Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas. Breast Cancer Res 2007;9(5):R65. Published online 2 October 2007, doi:10.1186/bcr1771
-
-
-
-
10
-
-
33745653114
-
Metaplastic breast carcinomas are basal-like tumours
-
Reis-Filho JS, Milanezi F, Steele D, et al. Metaplastic breast carcinomas are basal-like tumours. Histopathology 2006;49(1):10-21
-
(2006)
Histopathology
, vol.49
, Issue.1
, pp. 10-21
-
-
Reis-Filho, J.S.1
Milanezi, F.2
Steele, D.3
-
11
-
-
22344443194
-
Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype
-
Lakhani SR, Reis-Filho JS, Fulford L, et al. Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin Cancer Res 2005;11(14):5175-80
-
(2005)
Clin Cancer Res
, vol.11
, Issue.14
, pp. 5175-5180
-
-
Lakhani, S.R.1
Reis-Filho, J.S.2
Fulford, L.3
-
12
-
-
0024604022
-
Adenoid cystic carcinoma of the breast: A histologic, cytologic, and immunohistochemical study
-
Lamovec J, Us-Krasovec M, Zidar A, Kljun A. Adenoid cystic carcinoma of the breast: a histologic, cytologic, and immunohistochemical study. Semin Diagn Pathol 1989;6(2):153-64
-
(1989)
Semin Diagn Pathol
, vol.6
, Issue.2
, pp. 153-164
-
-
Lamovec, J.1
Us-Krasovec, M.2
Zidar, A.3
Kljun, A.4
-
13
-
-
0032896905
-
Estrogen receptor status by immunchistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
-
Harvey JM, Clark GM, Osborne CK, Allred DC. Estrogen receptor status by immunchistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J Clin Oncol 1999;17(5):1474-81
-
(1999)
J Clin Oncol
, vol.17
, Issue.5
, pp. 1474-1481
-
-
Harvey, J.M.1
Clark, G.M.2
Osborne, C.K.3
Allred, D.C.4
-
14
-
-
43949095489
-
How basal are triple-negative breast cancers?
-
Bertucci I, Finetti P, Cervera N, et al. How basal are triple-negative breast cancers? Int J Cancer 2008;123(1):236-40
-
(2008)
Int J Cancer
, vol.123
, Issue.1
, pp. 236-240
-
-
Bertucci, I.1
Finetti, P.2
Cervera, N.3
-
15
-
-
33744960226
-
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
-
Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006;2492-502
-
(2006)
JAMA
, pp. 2492-2502
-
-
Carey, L.A.1
Perou, C.M.2
Livasy, C.A.3
-
16
-
-
0029928658
-
The impact of stage and histology on the long-term clinical course of 163,808 patients with breast carcinoma
-
Gamel JW, Meyer JS, Feuer E, Miller BA. The impact of stage and histology on the long-term clinical course of 163,808 patients with breast carcinoma. Cancer 1996;77(8):1459-64
-
(1996)
Cancer
, vol.77
, Issue.8
, pp. 1459-1464
-
-
Gamel, J.W.1
Meyer, J.S.2
Feuer, E.3
Miller, B.A.4
-
17
-
-
0033281725
-
The pathology of familial breast cancer: The pre-BRCA1/ BRCA2 era: historical perspectives
-
van de Vijver MJ. The pathology of familial breast cancer: the pre-BRCA1/ BRCA2 era: historical perspectives. Breast Cancer Res 1999;1(1):27-30
-
(1999)
Breast Cancer Res
, vol.1
, Issue.1
, pp. 27-30
-
-
van de Vijver, M.J.1
-
18
-
-
34248145042
-
-
Harris LN, Broadwater G, Lin NU, et al. Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342. Breast Cancer Res 2006;8(6):R66. Published online 27 November 2006, doi:10.11861bcr1622
-
Harris LN, Broadwater G, Lin NU, et al. Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342. Breast Cancer Res 2006;8(6):R66. Published online 27 November 2006, doi:10.11861bcr1622
-
-
-
-
19
-
-
34247381115
-
Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer
-
Haffty BG, Yang Q, Reiss M, et al. Locoregional relapse and distant metastasis in conservatively managed triple negative early-stage breast cancer. J Clin Oncol 2006;24(36):5652-7
-
(2006)
J Clin Oncol
, vol.24
, Issue.36
, pp. 5652-5657
-
-
Haffty, B.G.1
Yang, Q.2
Reiss, M.3
-
20
-
-
34248218713
-
-
Fulford LG, Reis-Filho JS, Ryder K, et al. Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Res 2007;9(1):R4. Published online 11 January 2007, doi:10.1186/bcr1636
-
Fulford LG, Reis-Filho JS, Ryder K, et al. Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. Breast Cancer Res 2007;9(1):R4. Published online 11 January 2007, doi:10.1186/bcr1636
-
-
-
-
21
-
-
33645072444
-
Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas
-
Rodriguez-Pinilta SM, Sarrio D, et al. Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas. Clin Cancer Res 2006;12(5):1533-9
-
(2006)
Clin Cancer Res
, vol.12
, Issue.5
, pp. 1533-1539
-
-
Rodriguez-Pinilta, S.M.1
Sarrio, D.2
-
22
-
-
33748040055
-
Breast cancers with brain metastases are more likely to be estrogen receptor negative, express the basal cytokeratin CK5/6, and overexpress HER2 or EGFR
-
Hicks DG, Short SM, Prescott NL, et al. Breast cancers with brain metastases are more likely to be estrogen receptor negative, express the basal cytokeratin CK5/6, and overexpress HER2 or EGFR. Am J Surg Pathol 2006;30(9):1097-104
-
(2006)
Am J Surg Pathol
, vol.30
, Issue.9
, pp. 1097-1104
-
-
Hicks, D.G.1
Short, S.M.2
Prescott, N.L.3
-
23
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 2008;26(8):1275-81
-
(2008)
J Clin Oncol
, vol.26
, Issue.8
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
-
24
-
-
39149137567
-
Advances in adjuvant endocrine therapy for postmenopausal women
-
Lin NU, Winer EP. Advances in adjuvant endocrine therapy for postmenopausal women. J Clin Oncol 2008;26(5):798-805
-
(2008)
J Clin Oncol
, vol.26
, Issue.5
, pp. 798-805
-
-
Lin, N.U.1
Winer, E.P.2
-
25
-
-
39149088369
-
Controversies in the management of patients with breast cancer: Adjuvant endocrine therapy in premenopausal women
-
Parton M, Smith IE. Controversies in the management of patients with breast cancer: adjuvant endocrine therapy in premenopausal women. J Clin Oncol 2008;26(5):745-52
-
(2008)
J Clin Oncol
, vol.26
, Issue.5
, pp. 745-752
-
-
Parton, M.1
Smith, I.E.2
-
26
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J, et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005;353(16):1673-84
-
(2005)
N Engl J Med
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
27
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005;353(16):1659-72
-
(2005)
N Engl J Med
, vol.353
, Issue.16
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
28
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C, Neo SY, McShane LM, et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 2003;100(18):10393-8
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.18
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
-
29
-
-
23844549918
-
Breast cancer molecular subtypes respond differently to preoperative chemotherapy
-
Rouzier R, Perou CM, Symmans WF, et al. Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin Cancer Res 2005;11(16):5678-85
-
(2005)
Clin Cancer Res
, vol.11
, Issue.16
, pp. 5678-5685
-
-
Rouzier, R.1
Perou, C.M.2
Symmans, W.F.3
-
30
-
-
38949161181
-
-
Rakha E, Ellis I, Reis-Filho J. Are triple-negative and basal-like breast cancer synonymous? Clin Cancer Res 2008;14(2):618; author reply 618-9
-
Rakha E, Ellis I, Reis-Filho J. Are triple-negative and basal-like breast cancer synonymous? Clin Cancer Res 2008;14(2):618; author reply 618-9
-
-
-
-
31
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004;10(16):5367-74
-
(2004)
Clin Cancer Res
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
-
32
-
-
40949121882
-
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
-
Cheang MC, Voduc D, Bajdik C, et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin Cancer Res 2008;14(5):1368-76
-
(2008)
Clin Cancer Res
, vol.14
, Issue.5
, pp. 1368-1376
-
-
Cheang, M.C.1
Voduc, D.2
Bajdik, C.3
-
33
-
-
37248999372
-
Triple negative tumours: A critical review
-
Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathology 2008;52(1):108-18
-
(2008)
Histopathology
, vol.52
, Issue.1
, pp. 108-118
-
-
Reis-Filho, J.S.1
Tutt, A.N.2
-
34
-
-
45149094267
-
Basal-like breast cancer: A critical review
-
Rakha EA, Reis-Filho JS, Ellis IO. Basal-like breast cancer: a critical review. J Clin Oncol 2008;26(15):2568-81
-
(2008)
J Clin Oncol
, vol.26
, Issue.15
, pp. 2568-2581
-
-
Rakha, E.A.1
Reis-Filho, J.S.2
Ellis, I.O.3
-
35
-
-
33746547467
-
-
Perreard L, Fan C, Quackenbush JF, et al. Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay. Breast Cancer Res 2006;8(2):R23. Published online 20 April 2006, doi:10.1186/bcr1399
-
Perreard L, Fan C, Quackenbush JF, et al. Classification and risk stratification of invasive breast carcinomas using a real-time quantitative RT-PCR assay. Breast Cancer Res 2006;8(2):R23. Published online 20 April 2006, doi:10.1186/bcr1399
-
-
-
-
36
-
-
34547852260
-
Does triple-negative phenotype accurately identify basal-like tumour? An immunohistochemical analysis based on 143 'triple-negative' breast cancers
-
Bidard FC, Conforti R, Boulet T, et al. Does triple-negative phenotype accurately identify basal-like tumour? An immunohistochemical analysis based on 143 'triple-negative' breast cancers. Ann Oncol 2007;18(7):1285-6
-
(2007)
Ann Oncol
, vol.18
, Issue.7
, pp. 1285-1286
-
-
Bidard, F.C.1
Conforti, R.2
Boulet, T.3
-
37
-
-
10744223743
-
The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/ glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer
-
Foulkes WD, Brunet JS, Stefansson IM, et al. The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/ glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer. Cancer Res 2004;64(3):830-5
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 830-835
-
-
Foulkes, W.D.1
Brunet, J.S.2
Stefansson, I.M.3
-
38
-
-
33646874546
-
-
Hu Z, Fan C, Oh DS, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006;7:96. Published online 27 April 2006, doi:10.1186/1471-2164-7-96
-
Hu Z, Fan C, Oh DS, et al. The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics 2006;7:96. Published online 27 April 2006, doi:10.1186/1471-2164-7-96
-
-
-
-
39
-
-
30944468766
-
Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue
-
Reis-Filho JS, Steele D, Di Palma S, et al. Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue. Mod Pathol 2006;19(2):307-19
-
(2006)
Mod Pathol
, vol.19
, Issue.2
, pp. 307-319
-
-
Reis-Filho, J.S.1
Steele, D.2
Di Palma, S.3
-
40
-
-
33846288318
-
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis
-
Savage K, Lambros MB, Robertson D, et al. Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res 2007;13(1):90-101
-
(2007)
Clin Cancer Res
, vol.13
, Issue.1
, pp. 90-101
-
-
Savage, K.1
Lambros, M.B.2
Robertson, D.3
-
41
-
-
34548680053
-
Moesin expression is a marker of basal breast carcinomas
-
Charafe-Jauffret E, Monville F, Bertucci F, et al. Moesin expression is a marker of basal breast carcinomas. Int J Cancer 2007;121(8):1779-85
-
(2007)
Int J Cancer
, vol.121
, Issue.8
, pp. 1779-1785
-
-
Charafe-Jauffret, E.1
Monville, F.2
Bertucci, F.3
-
42
-
-
37449017051
-
αB-crystallin: A novel marker of invasive basal-like and metaplastic breast carcinomas
-
Sitterding SM, Wiseman WR, Schiller CL, et al. αB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas. Ann Diagn Pathol 2008;12(1):33-40
-
(2008)
Ann Diagn Pathol
, vol.12
, Issue.1
, pp. 33-40
-
-
Sitterding, S.M.1
Wiseman, W.R.2
Schiller, C.L.3
-
43
-
-
31044433169
-
αB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer
-
Moyano JV, Evans JR, Chen F, et al. αB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer. J Clin Invest 2006;116(1):261-70
-
(2006)
J Clin Invest
, vol.116
, Issue.1
, pp. 261-270
-
-
Moyano, J.V.1
Evans, J.R.2
Chen, F.3
-
44
-
-
33947246109
-
Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer
-
Harris LN, You F, Schnitt SJ, et al. Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer. Clin Cancer Res 2007;13(4):1198-207
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1198-1207
-
-
Harris, L.N.1
You, F.2
Schnitt, S.J.3
-
45
-
-
33744760541
-
BRCA1 and BRCA2: Chemosensitivity, treatment outcomes and prognosis
-
Foulkes WD. BRCA1 and BRCA2: chemosensitivity, treatment outcomes and prognosis. Fam Cancer 2006;5(2):135-42
-
(2006)
Fam Cancer
, vol.5
, Issue.2
, pp. 135-142
-
-
Foulkes, W.D.1
-
46
-
-
34250377983
-
Therapeutic potential of drugs to modulate DNA repair in cancer
-
Curtin N. Therapeutic potential of drugs to modulate DNA repair in cancer. Expert Opin Ther Targets 2007;11(6):783-99
-
(2007)
Expert Opin Ther Targets
, vol.11
, Issue.6
, pp. 783-799
-
-
Curtin, N.1
-
47
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005;434(7035):917-21
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
-
48
-
-
33746100822
-
Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer
-
Tutt AN, Lord CJ, McCabe N, et al. Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer. Cold Spring Harb Symp Quant Biol 2005;70:139-48
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 139-148
-
-
Tutt, A.N.1
Lord, C.J.2
McCabe, N.3
-
49
-
-
38449117440
-
Molecular basis for estrogen receptor a deficiency in BRCA1-linked breast cancer
-
Hosey AM, Gorski JJ, Murray MM, et al. Molecular basis for estrogen receptor a deficiency in BRCA1-linked breast cancer. J Natl Cancer Inst 2007;99(22):1683-94
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.22
, pp. 1683-1694
-
-
Hosey, A.M.1
Gorski, J.J.2
Murray, M.M.3
-
50
-
-
33749022506
-
Basal-like breast cancer and the BRCA1 phenotype
-
Turner NC, Reis-Filho JS. Basal-like breast cancer and the BRCA1 phenotype. Oncogene 2006;25(43):5846-53
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5846-5853
-
-
Turner, N.C.1
Reis-Filho, J.S.2
-
51
-
-
33749025026
-
Pathology and gene expression of hereditary breast tumors associated with BRCA1, BRCA2 and CHEK2 gene mutations
-
Honrado E, Osorio A, Palacios J, Benitez J. Pathology and gene expression of hereditary breast tumors associated with BRCA1, BRCA2 and CHEK2 gene mutations. Oncogene 2006;25(43):5837-45
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5837-5845
-
-
Honrado, E.1
Osorio, A.2
Palacios, J.3
Benitez, J.4
-
52
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
Turner NC, Reis-Filho JS, Russell AM, et al. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2007;26(14):2126-32
-
(2007)
Oncogene
, vol.26
, Issue.14
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
-
53
-
-
0038207152
-
Prognostic significance of BRCA1 expression in sporadic breast carcinomas
-
Lambie H, Miremadi A, Pinder SE, et al. Prognostic significance of BRCA1 expression in sporadic breast carcinomas. J Pathol 2003;200(2):207-13
-
(2003)
J Pathol
, vol.200
, Issue.2
, pp. 207-213
-
-
Lambie, H.1
Miremadi, A.2
Pinder, S.E.3
-
54
-
-
44649095619
-
Expression of BRCA1 protein in breast cancer and its prognostic significance
-
Rakha EA, El-Sheikh SE, Kandil MA, et al. Expression of BRCA1 protein in breast cancer and its prognostic significance. Hum Pathol 2008;39(6):857-65
-
(2008)
Hum Pathol
, vol.39
, Issue.6
, pp. 857-865
-
-
Rakha, E.A.1
El-Sheikh, S.E.2
Kandil, M.A.3
-
55
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000;92(7):564-9
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.7
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
56
-
-
0043246688
-
Distinct genetic and epigenetic changes in medullary breast cancer
-
Osin P, Lu YJ, Stone J, et al. Distinct genetic and epigenetic changes in medullary breast cancer. Int J Surg Pathol 2003;11(3):153-8
-
(2003)
Int J Surg Pathol
, vol.11
, Issue.3
, pp. 153-158
-
-
Osin, P.1
Lu, Y.J.2
Stone, J.3
-
57
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner N, Tutt A, Ashworth A. Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev 2004;4(10):814-9
-
(2004)
Nat Rev
, vol.4
, Issue.10
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
58
-
-
33748073782
-
Targeting the double-strand DNA break repair pathway as a therapeutic strategy
-
Lord CJ, Garrett MD, Ashworth A. Targeting the double-strand DNA break repair pathway as a therapeutic strategy. Clin Cancer Res 2006;12(15):4463-8
-
(2006)
Clin Cancer Res
, vol.12
, Issue.15
, pp. 4463-4468
-
-
Lord, C.J.1
Garrett, M.D.2
Ashworth, A.3
-
59
-
-
33847339743
-
A mouse model of basal-like breast carcinoma with metaplastic elements
-
McCarthy A, Savage K, Gabriel A, et al. A mouse model of basal-like breast carcinoma with metaplastic elements. J Pathol 2007;211(4):389-98
-
(2007)
J Pathol
, vol.211
, Issue.4
, pp. 389-398
-
-
McCarthy, A.1
Savage, K.2
Gabriel, A.3
-
60
-
-
34547496282
-
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer
-
Liu X, Holstege H, van der Gulden H, et al. Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer. Proc Natl Acad Sci USA 2007; 104(29):12111-6
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.29
, pp. 12111-12116
-
-
Liu, X.1
Holstege, H.2
van der Gulden, H.3
-
61
-
-
47549107072
-
Triple negative breast cancer: Molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
-
6 October, doi:10.1007/s10549-007-9756-8
-
Tan DS, Marchio C, Jones RL, et al. Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. Breast Cancer Res Treat 2007: published online 6 October 2007, doi:10.1007/s10549-007-9756-8
-
(2007)
Breast Cancer Res Treat 2007: Published online
-
-
Tan, D.S.1
Marchio, C.2
Jones, R.L.3
-
62
-
-
34547836352
-
Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: A biomarker study from two randomized trials
-
Conforti R, Boulet T, Tomasic G, et al. Breast cancer molecular subclassification and estrogen receptor expression to predict efficacy of adjuvant anthracyclines-based chemotherapy: a biomarker study from two randomized trials. Ann Oncol 2007;18(9):1477-83
-
(2007)
Ann Oncol
, vol.18
, Issue.9
, pp. 1477-1483
-
-
Conforti, R.1
Boulet, T.2
Tomasic, G.3
-
63
-
-
0025063119
-
Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, mediotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: Results from the National Surgical Adjuvant Breast and Bowel Project B-15
-
Fisher B, Brown AM, Dimitrov NV, et al. Two months of doxorubicin-cyclophosphamide with and without interval reinduction therapy compared with 6 months of cyclophosphamide, mediotrexate, and fluorouracil in positive-node breast cancer patients with tamoxifen-nonresponsive tumors: results from the National Surgical Adjuvant Breast and Bowel Project B-15. J Clin Oncol 1990;8(9):1483-96
-
(1990)
J Clin Oncol
, vol.8
, Issue.9
, pp. 1483-1496
-
-
Fisher, B.1
Brown, A.M.2
Dimitrov, N.V.3
-
64
-
-
0037445132
-
Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer
-
Henderson IC, Berry DA, Demetri GD, et al. Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol 2003;21(6):976-83
-
(2003)
J Clin Oncol
, vol.21
, Issue.6
, pp. 976-983
-
-
Henderson, I.C.1
Berry, D.A.2
Demetri, G.D.3
-
65
-
-
35248895346
-
HER2 and response to paclitaxel in node-positive breast cancer
-
Hayes DF, Thor AD, Dressler LG, et al. HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med 2007;357(15):1496-506
-
(2007)
N Engl J Med
, vol.357
, Issue.15
, pp. 1496-1506
-
-
Hayes, D.F.1
Thor, A.D.2
Dressler, L.G.3
-
66
-
-
34247329446
-
Sequential adjuvant epirubicin-based and docetaxel chemotherapy for node-positive breast cancer patients: The FNCLCC PACS 01 Trial
-
Roche H, Fumoleau P, Spielmann M, et al. Sequential adjuvant epirubicin-based and docetaxel chemotherapy for node-positive breast cancer patients: the FNCLCC PACS 01 Trial. J Clin Oncol 2006;24(36):5664-71
-
(2006)
J Clin Oncol
, vol.24
, Issue.36
, pp. 5664-5671
-
-
Roche, H.1
Fumoleau, P.2
Spielmann, M.3
-
67
-
-
21144435932
-
Adjuvant docetaxel for node-positive breast cancer
-
Martin M, Pienkowski T, Mackey J, et al. Adjuvant docetaxel for node-positive breast cancer. N Engl J Med 2005;352(22):2302-13
-
(2005)
N Engl J Med
, vol.352
, Issue.22
, pp. 2302-2313
-
-
Martin, M.1
Pienkowski, T.2
Mackey, J.3
-
68
-
-
58849160766
-
Preliminary results of the UK Taxotere as Adjuvant Chemotherapy (TACT) trial [abstract 78]
-
Ellis PA, Barrett-Lee PJ, Bloomfield D, et al. Preliminary results of the UK Taxotere as Adjuvant Chemotherapy (TACT) trial [abstract 78]. Breast Cancer Res Treat 2007;106(Suppl 1):S21
-
(2007)
Breast Cancer Res Treat
, vol.106
, Issue.SUPPL. 1
-
-
Ellis, P.A.1
Barrett-Lee, P.J.2
Bloomfield, D.3
-
69
-
-
37549025804
-
BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy
-
Quinn JE, James CR, Stewart GE, et al. BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy. Clin Cancer Res 2007;13(24):7413-20
-
(2007)
Clin Cancer Res
, vol.13
, Issue.24
, pp. 7413-7420
-
-
Quinn, J.E.1
James, C.R.2
Stewart, G.E.3
-
70
-
-
39749119151
-
Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancers
-
Byrski T, Gronwald J, Huzarski T, et al. Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancers. Breast Cancer Res Treat 2008;108(2):289-96
-
(2008)
Breast Cancer Res Treat
, vol.108
, Issue.2
, pp. 289-296
-
-
Byrski, T.1
Gronwald, J.2
Huzarski, T.3
-
71
-
-
0033527717
-
-
Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science (New York), NY 1999;286(5442):1162-6
-
Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science (New York), NY 1999;286(5442):1162-6
-
-
-
-
72
-
-
0033637170
-
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
-
Tibbetts RS, Cortez D, Brumbaugh KM, et al. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev 2000;14(23):2989-3002
-
(2000)
Genes Dev
, vol.14
, Issue.23
, pp. 2989-3002
-
-
Tibbetts, R.S.1
Cortez, D.2
Brumbaugh, K.M.3
-
73
-
-
0034624718
-
hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
-
Lee JS, Collins KM, Brown AL, et al. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 2000;404(6774):201-4
-
(2000)
Nature
, vol.404
, Issue.6774
, pp. 201-204
-
-
Lee, J.S.1
Collins, K.M.2
Brown, A.L.3
-
74
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, et al. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000;14(8):927-39
-
(2000)
Genes Dev
, vol.14
, Issue.8
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
-
75
-
-
9744263911
-
The role of BRCA1 in the cellular response to chemotherapy
-
Kennedy RD, Quinn JE, Mullan PB, et al. The role of BRCA1 in the cellular response to chemotherapy. J Natl Cancer Inst 2004;96(22):1659-68
-
(2004)
J Natl Cancer Inst
, vol.96
, Issue.22
, pp. 1659-1668
-
-
Kennedy, R.D.1
Quinn, J.E.2
Mullan, P.B.3
-
76
-
-
33749023326
-
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
-
Gudmundsdottir K, Ashworth A. The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene 2006;25(43):5864-74
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5864-5874
-
-
Gudmundsdottir, K.1
Ashworth, A.2
-
77
-
-
0038147067
-
BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells
-
Tassone P, Tagliaferri P, Perricelli A, et al. BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cells. Br J Cancer 2003;88(8):1285-91
-
(2003)
Br J Cancer
, vol.88
, Issue.8
, pp. 1285-1291
-
-
Tassone, P.1
Tagliaferri, P.2
Perricelli, A.3
-
78
-
-
0141954010
-
BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
-
Quinn JE, Kennedy RD, Mullan PB, et al. BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis. Cancer Res 2003;63(19):6221-8
-
(2003)
Cancer Res
, vol.63
, Issue.19
, pp. 6221-6228
-
-
Quinn, J.E.1
Kennedy, R.D.2
Mullan, P.B.3
-
79
-
-
0034604716
-
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
-
Bhattacharyya A, Ear US, Koller BH, et al. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 2000;275(31):23899-903
-
(2000)
J Biol Chem
, vol.275
, Issue.31
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
-
80
-
-
34547504504
-
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
-
Rottenberg S, Nygren AO, Pajic M, et al. Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer. Proc Natl Acad Sci USA 2007;104(29):12117-22
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.29
, pp. 12117-12122
-
-
Rottenberg, S.1
Nygren, A.O.2
Pajic, M.3
-
81
-
-
51549104997
-
First in human phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU-0059436 (Ku), a small molecule inhibitor of poly ADP-ribose polymerase (PARP) in cancer patients (p), including BRCA1/2 mutation carriers
-
abstract 3529
-
Yap T, Boss D, Fong P, et al. First in human phase I pharmacokinetic (PK) and pharmacodynamic (PD) study of KU-0059436 (Ku), a small molecule inhibitor of poly ADP-ribose polymerase (PARP) in cancer patients (p), including BRCA1/2 mutation carriers [abstract 3529]. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007;25(18S Suppl)
-
ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007;25(18S Suppl)
-
-
Yap, T.1
Boss, D.2
Fong, P.3
-
82
-
-
33746961739
-
Mechanisms of disease: Oncogene addiction - a rationale for molecular targeting in cancer therapy
-
Weinstein IB, Joe AK. Mechanisms of disease: Oncogene addiction - a rationale for molecular targeting in cancer therapy. Nat Clin Pract 2006;3(8):448-57
-
(2006)
Nat Clin Pract
, vol.3
, Issue.8
, pp. 448-457
-
-
Weinstein, I.B.1
Joe, A.K.2
-
83
-
-
1642494767
-
KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations
-
Simon R, Panussis S, Maurer R, et al. KIT (CD117)-positive breast cancers are infrequent and lack KIT gene mutations. Clin Cancer Res 2004; 10(1 Pt 1): 178-83
-
(2004)
Clin Cancer Res
, vol.10
, Issue.1 PART 1
, pp. 178-183
-
-
Simon, R.1
Panussis, S.2
Maurer, R.3
-
84
-
-
0041802378
-
Phase II and tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer
-
Baselga J, Albanell J, Ruiz A, et al. Phase II and tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer. Proc Am Soc Clin Oncol 2003;22(24)
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, Issue.24
-
-
Baselga, J.1
Albanell, J.2
Ruiz, A.3
-
85
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd F, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353(2):123-32
-
(2005)
N Engl J Med
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
86
-
-
33746911642
-
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
-
Reis-Filho JS, Pinheiro C, Lambros MB, et al. EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J Pathol 2006;209(4):445-53
-
(2006)
J Pathol
, vol.209
, Issue.4
, pp. 445-453
-
-
Reis-Filho, J.S.1
Pinheiro, C.2
Lambros, M.B.3
-
87
-
-
84925550146
-
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis
-
Reis-Filho JS, Milanezi F, Carvalho S, et al. Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Res 2005;7(6):R1028-35
-
(2005)
Breast Cancer Res
, vol.7
, Issue.6
-
-
Reis-Filho, J.S.1
Milanezi, F.2
Carvalho, S.3
-
88
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Bonner JA, Harari PM, Giralt J, et al. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006;354(6):567-78
-
(2006)
N Engl J Med
, vol.354
, Issue.6
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
-
89
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humbler Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004;351(4):337-45
-
(2004)
N Engl J Med
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humbler, Y.2
Siena, S.3
-
90
-
-
35248889408
-
-
Hoadley KA, Weigman VJ, Fan C, et al. EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 2007;8:258. Published online 31 July 2007, doi:10.1186/1471-2164-8-258
-
Hoadley KA, Weigman VJ, Fan C, et al. EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 2007;8:258. Published online 31 July 2007, doi:10.1186/1471-2164-8-258
-
-
-
-
91
-
-
35748966462
-
-
Grimaldi AM, Guida T, D'Arrino R, et al. Sunitinib: bridging present and future cancer treatment. Ann Oncol 2007;18(Supp] 6):vi31-4
-
Grimaldi AM, Guida T, D'Arrino R, et al. Sunitinib: bridging present and future cancer treatment. Ann Oncol 2007;18(Supp] 6):vi31-4
-
-
-
-
92
-
-
2442669093
-
Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer
-
Abrams TJ, Murray LJ, Pesenti E, et al. Preclinical evaluation of the tyrosine kinase inhibitor SU11248 as a single agent and in combination with "standard of care" therapeutic agents for the treatment of breast cancer. Mol Cancer Ther 2003;2(10):1011-21
-
(2003)
Mol Cancer Ther
, vol.2
, Issue.10
, pp. 1011-1021
-
-
Abrams, T.J.1
Murray, L.J.2
Pesenti, E.3
-
93
-
-
42949148257
-
Phase II study of Sunitinib Malate, an oral mullitargeted cyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
Burstein HJ, Elias AD, Rugo HS, et al. Phase II study of Sunitinib Malate, an oral mullitargeted cyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol 2008;26(11):1810-6
-
(2008)
J Clin Oncol
, vol.26
, Issue.11
, pp. 1810-1816
-
-
Burstein, H.J.1
Elias, A.D.2
Rugo, H.S.3
-
94
-
-
34548701082
-
Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro
-
Finn RS, Dering J, Ginther C, et al. Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro. Breast Cancer Res Treat 2007;105(3):319-26
-
(2007)
Breast Cancer Res Treat
, vol.105
, Issue.3
, pp. 319-326
-
-
Finn, R.S.1
Dering, J.2
Ginther, C.3
-
95
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354(24):2531-41
-
(2006)
N Engl J Med
, vol.354
, Issue.24
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
96
-
-
45149087139
-
Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
-
Hochhaus A, Baccarani M, Deininger M, et al. Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib. Leukemia 2008;22(6):1200-6
-
(2008)
Leukemia
, vol.22
, Issue.6
, pp. 1200-1206
-
-
Hochhaus, A.1
Baccarani, M.2
Deininger, M.3
-
97
-
-
0030474489
-
c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis
-
Verbeek BS, Vroom TM, Adriaansen-Slot SS, et al. c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis. J Pathol 1996;180(4):383-8
-
(1996)
J Pathol
, vol.180
, Issue.4
, pp. 383-388
-
-
Verbeek, B.S.1
Vroom, T.M.2
Adriaansen-Slot, S.S.3
-
98
-
-
0041513490
-
C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis
-
Myoui A, Nishimura R, Williams PJ, et al. C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis. Cancer Res 2003;63(16):5028-33
-
(2003)
Cancer Res
, vol.63
, Issue.16
, pp. 5028-5033
-
-
Myoui, A.1
Nishimura, R.2
Williams, P.J.3
-
99
-
-
33947225176
-
Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: Rationale for patient selection
-
Huang F, Reeves K, Han X, et al. Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection. Cancer Res 2007;67(5):2226-38
-
(2007)
Cancer Res
, vol.67
, Issue.5
, pp. 2226-2238
-
-
Huang, F.1
Reeves, K.2
Han, X.3
-
100
-
-
44849132293
-
Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: An immunofluorescence and immunohistochemical analysis
-
Savage K, Leung S, Todd SK, et al. Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis. Breast Cancer Res Treat 2008;110(2):245-56
-
(2008)
Breast Cancer Res Treat
, vol.110
, Issue.2
, pp. 245-256
-
-
Savage, K.1
Leung, S.2
Todd, S.K.3
-
101
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82(1):4-6
-
(1990)
J Natl Cancer Inst
, vol.82
, Issue.1
, pp. 4-6
-
-
Folkman, J.1
-
102
-
-
33645551935
-
Vascular endothelial growth factor expression in the basal subtype of breast carcinoma
-
Ribeiro-Silva A, Ribeiro do Vale F, Zucoloto S. Vascular endothelial growth factor expression in the basal subtype of breast carcinoma. Am J Clin Pathol 2006;125(4):512-8
-
(2006)
Am J Clin Pathol
, vol.125
, Issue.4
, pp. 512-518
-
-
Ribeiro-Silva, A.1
Ribeiro do Vale, F.2
Zucoloto, S.3
-
103
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, rumor growth factor β-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M, LeJeune S, Scott PA, et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, rumor growth factor β-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997;57(5):963-9
-
(1997)
Cancer Res
, vol.57
, Issue.5
, pp. 963-969
-
-
Relf, M.1
LeJeune, S.2
Scott, P.A.3
-
104
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006;355(24):2542-50
-
(2006)
N Engl J Med
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
105
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350(23):2335-42
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
106
-
-
0242468884
-
A phase I/II dose-escalation trial of bevacizumab in previously created metastatic breast cancer
-
Cobleigh MA, Langmuir VK, Sledge GW, et al. A phase I/II dose-escalation trial of bevacizumab in previously created metastatic breast cancer. Semin Oncol 2003;30(5 Suppl 16):117-24
-
(2003)
Semin Oncol
, vol.30
, Issue.5 SUPPL. 16
, pp. 117-124
-
-
Cobleigh, M.A.1
Langmuir, V.K.2
Sledge, G.W.3
-
107
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357(26):2666-76
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
108
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Holmes FA, et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005;23(4):792-9
-
(2005)
J Clin Oncol
, vol.23
, Issue.4
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
110
-
-
58149237789
-
TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype
-
1 February, doi:10.1007/ s10549-008-9924-5
-
Rahman M, Davis SR, Pumphrey JG, et al. TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype. Breast Cancer Res Treat 2008; published online 1 February 2008, doi:10.1007/ s10549-008-9924-5
-
(2008)
Breast Cancer Res Treat 2008; published online
-
-
Rahman, M.1
Davis, S.R.2
Pumphrey, J.G.3
-
111
-
-
34248187996
-
Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand recepror-1
-
Tolcher AW, Mica M, Meropol NJ, et al. Phase I pharmacokinetic and biologic correlative study of mapatumumab, a fully human monoclonal antibody with agonist activity to tumor necrosis factor-related apoptosis-inducing ligand recepror-1. J Clin Oncol 2007;25(11):1390-5
-
(2007)
J Clin Oncol
, vol.25
, Issue.11
, pp. 1390-1395
-
-
Tolcher, A.W.1
Mica, M.2
Meropol, N.J.3
-
112
-
-
34548132882
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers
-
Kendrick JE, Estes JM, Straughn JM Jr, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers. Gynecol Oncol 2007;106(3):614-21
-
(2007)
Gynecol Oncol
, vol.106
, Issue.3
, pp. 614-621
-
-
Kendrick, J.E.1
Estes, J.M.2
Straughn Jr, J.M.3
-
113
-
-
0033083990
-
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines
-
Keane MM, Ettenberg SA, Nau MM, et al. Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. Cancer Res 1999;59(3):734-41
-
(1999)
Cancer Res
, vol.59
, Issue.3
, pp. 734-741
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nau, M.M.3
-
114
-
-
33749030177
-
Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer
-
Hess KR, Anderson K, Symmans WF, et al. Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer. J Clin Oncol 2006;24(26):4236-44
-
(2006)
J Clin Oncol
, vol.24
, Issue.26
, pp. 4236-4244
-
-
Hess, K.R.1
Anderson, K.2
Symmans, W.F.3
-
115
-
-
33750976943
-
Deconstructing the molecular portrait of basal-like breast cancer
-
Yehiely F, Moyano JV, Evans JR, et al. Deconstructing the molecular portrait of basal-like breast cancer. Trends Mol Med 2006;12(11):537-44
-
(2006)
Trends Mol Med
, vol.12
, Issue.11
, pp. 537-544
-
-
Yehiely, F.1
Moyano, J.V.2
Evans, J.R.3
-
116
-
-
34447552512
-
Getting it right: Designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research
-
Tan DS, Lambros MB, Natrajan R, Reis-Filho JS. Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research. Lab Invest J Tech Methods Pathol 2007;87(8):737-54
-
(2007)
Lab Invest J Tech Methods Pathol
, vol.87
, Issue.8
, pp. 737-754
-
-
Tan, D.S.1
Lambros, M.B.2
Natrajan, R.3
Reis-Filho, J.S.4
-
117
-
-
34447498286
-
-
Bost WJ. Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery. BMC Syst Biol 2007;1:13. Published online 15 February 2007, doi:10.1186/1752-0509-1-13
-
Bost WJ. Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery. BMC Syst Biol 2007;1:13. Published online 15 February 2007, doi:10.1186/1752-0509-1-13
-
-
-
-
118
-
-
32044451325
-
Cancer: A systems biology disease
-
Hornberg JJ, Bruggeman FJ, Westerhoff HV, Lankelma J. Cancer: a systems biology disease. Bio Syst 2006;83(2-3):81-90
-
(2006)
Bio Syst
, vol.83
, Issue.2-3
, pp. 81-90
-
-
Hornberg, J.J.1
Bruggeman, F.J.2
Westerhoff, H.V.3
Lankelma, J.4
-
119
-
-
33845331706
-
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas
-
Reis-Filho JS, Simpson PT, Turner NC, et al. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res 2006;12(22):6652-62
-
(2006)
Clin Cancer Res
, vol.12
, Issue.22
, pp. 6652-6662
-
-
Reis-Filho, J.S.1
Simpson, P.T.2
Turner, N.C.3
-
120
-
-
9144271680
-
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
-
Cheng KW, Lahad JP, Kuo WL, et al. The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nat Med 2004;10(11):1251-6
-
(2004)
Nat Med
, vol.10
, Issue.11
, pp. 1251-1256
-
-
Cheng, K.W.1
Lahad, J.P.2
Kuo, W.L.3
-
121
-
-
34347391035
-
Utilizing RNA interference to enhance cancer drug discovery
-
Iorns E, Lord CJ, Turner N, Ashworth A. Utilizing RNA interference to enhance cancer drug discovery. Nat Rev Drug Discov 2007;6(7):556-68
-
(2007)
Nat Rev Drug Discov
, vol.6
, Issue.7
, pp. 556-568
-
-
Iorns, E.1
Lord, C.J.2
Turner, N.3
Ashworth, A.4
-
122
-
-
44949149181
-
Comparative genomic hybridisation arrays: High-throughput tools to determine targeted therapy in breast Cancer
-
Tan D, Reis-Filho J. Comparative genomic hybridisation arrays: high-throughput tools to determine targeted therapy in breast Cancer. Pathobiology 2008;75(2):63-74
-
(2008)
Pathobiology
, vol.75
, Issue.2
, pp. 63-74
-
-
Tan, D.1
Reis-Filho, J.2
-
123
-
-
51549116578
-
-
Available from:, Accessed on 8 April 2008
-
Available from: http://clinicaltrials.gov [Accessed on 8 April 2008]
-
-
-
|