Gene-expression profiles in hereditary breast cancer

New England Journal of Medicine

Volumn 344, Issue 8, 2001, Pages 539-548

  Hedenfalk, Ingrid ^a,c   Duggan, David ^a   Chen, Yidong ^a   Radmacher, Michael ^f   Bittner, Michael ^a   Simon, Richard ^b   Meltzer, Paul ^a   Gusterson, Barry ^d   Esteller, Manel ^e   Raffeld, Mark ^b   Yakhini, Zohar ^f   Ben Dor, Amir ^f   Dougherty, Edward ^f   Kononen, Juha ^f   Bubendorf, Lukas ^f   Fehrle, Wilfrid ^f   Pittaluga, Stefania ^f   Gruvberger, Sofia ^f   Loman, Niklas ^f   Johannsson, Oskar ^f   Olsson, Håkan ^f   Wilfond, Benjamin ^a   Sauter, Guido ^f   Kallioniemi, Olli P ^a   Borg, Ake ^c   Trent, Jeffrey ^a   more..

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f Bldg 49 ^*

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; RNA;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

ALGORITHMS; BRCA2 PROTEIN; BREAST NEOPLASMS; DNA METHYLATION; DNA, COMPLEMENTARY; DNA, NEOPLASM; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; GENOTYPE; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; RNA, NEOPLASM; TRANSCRIPTION FACTORS;

EID: 0035931947     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200102223440801     Document Type: Article

References (40)

1. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
2. Identification of the breast cancer susceptibility gene BRCA2
3. Risk of cancer in BRCA1-mutation carriers
4. Breast and ovarian cancer incidence in BRCA1-mutation carriers
5. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
6. Population-based study of risk of breast cancer in carriers of BRCA2 mutation
7. Population genetics of BRCA1 and BRCA2
8. Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus
9. Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: Linkage analysis in German breast cancer families
10. Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations
11. Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes
12. Tumour biological features of BRCA1-induced breast and ovarian cancer
13. Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women
14. Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1
15. Insights into the functions of BRCA1 and BRCA2
16. Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation
17. Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
18. Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer
19. Molecular classification of cutaneous malignant melanoma by gene expression profiling
20. Gene expression profiling of alveolar rhabdomyosarcoma with CDNA microarrays
21. Use of a cDNA microarray to analyse gene expression patterns in human cancer
22. Ratio-based decisions and the quantitative analysis of CDNA microarray images
23. Tissue microarrays for high-throughput molecular profiling of tumor specimens
24. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
25. Tightening the clinical trial
26. Pathology of familial breast cancer: Differences between breast cancers in carders of BRCA1 or BRCA2 mutations and sporadic cases
27. The pathology of familial breast cancer: Histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2
28. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
29. Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage
30. BRCA2 hereditary breast cancer pathophenotype
31. Inherited BRCA2 mutation associated with high grade breast cancer
32. Tissue classification with gene expression profiles
33. Biochemistry and genetics of eukaryotic mismatch repair
34. TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor ceils induced by growth factor withdrawal
35. Connective tissue growth factor induces apoptosis in human breast cancer cell line MCF-7
36. Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates
37. Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: Correlation with disease characteristics
38. Molecular portraits of human breast tumours
39. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2
40. Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations