CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in drosophila

Genes and Development

Volumn 26, Issue 22, 2012, Pages 2536-2549

  Luo, Weifei ^a   Li, Yue ^a   Tang, Chih Hang Anthony ^a   Abruzzi, Katharine C ^a   Rodriguez, Joseph ^a   Pescatore, Stefan ^a   Rosbash, Michael ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

Circadian rhythm; CLOCK; Deubiquitylation; Drosophila; Transcription; USP8

Indexed keywords

DROSOPHILA PROTEIN; MESSENGER RNA; PROTEINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CLOCK; TRANSCRIPTION FACTOR CYCLE; UBIQUITIN SPECIFIC PROTEASE 8; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CIRCADIAN RHYTHM; DOWN REGULATION; DROSOPHILA; FEEDBACK SYSTEM; INHIBITION KINETICS; LOCOMOTION; LOSS OF FUNCTION MUTATION; NERVE CELL; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA INTERFERENCE; TRANSCRIPTION REGULATION; UBIQUITINATION; WILD TYPE;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CLOCK PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; MOTOR ACTIVITY; PERIOD CIRCADIAN PROTEINS; PROTEIN ISOFORMS; RNA INTERFERENCE; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

ANIMALIA;

EID: 84869191713     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.200584.112     Document Type: Article

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