Rosmarinic acid ameliorates acute liver damage and fibrogenesis in carbon tetrachloride-intoxicated mice

Food and Chemical Toxicology

Volumn 51, Issue 1, 2013, Pages 370-378

  Domitrović, Robert ^a   Škoda, Marko ^a   Vasiljev Marchesi, Vanja ^a   Cvijanović, Olga ^a   Pernjak Pugel, Ester ^a   Štefan, Maja Bival ^b  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Apoptosis; Hepatotoxicity; Inflammation; Liver fibrosis; Oxidative nitrosative stress; Rosmarinic acid

Indexed keywords

3 NITROTYROSINE; ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOOXYGENASE 2; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ROSMARINIC ACID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIAPOPTOTIC ACTIVITY; ANTIFIBROTIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME DEGRADATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTOXICATION; LIVER FIBROSIS; LIVER NECROSIS; LIVER PARENCHYMA; LIVER PROTECTION; MALE; MOUSE; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INDUCTION; TOXIC HEPATITIS; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARBON TETRACHLORIDE; CARBON TETRACHLORIDE POISONING; CINNAMATES; CYCLOOXYGENASE 2; DEPSIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER; LIVER FAILURE, ACUTE; MALE; MICE; MICE, INBRED BALB C; NF-KAPPA B; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1;

MUS;

EID: 84868687096     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.10.021     Document Type: Article

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