Hepatoprotective activity of berberine is mediated by inhibition of TNF-α, COX-2, and iNOS expression in CCl4-intoxicated mice

Toxicology

Volumn 280, Issue 1-2, 2011, Pages 33-43

  Domitrović, Robert ^a   Jakovac, Hrvoje ^a   Blagojević, Gordana ^a  

^a UNIVERSITY OF RIJEKA   (Croatia)

Author keywords

Berberine; COX 2; Hepatotoxicity; INOS; Oxidative stress; TNF

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BERBERINE; CARBON TETRACHLORIDE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; SILYMARIN; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; HISTOPATHOLOGY; INHIBITION KINETICS; INTOXICATION; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; BERBERINE; CARBON TETRACHLORIDE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DRUG-INDUCED LIVER INJURY; LIVER; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE SYNTHASE TYPE II; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 78650522908     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.11.005     Document Type: Article

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