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Volumn 24, Issue 5, 2010, Pages 886-897

FXR regulates liver repair after CCl4-induced toxic injury

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CARBON TETRACHLORIDE; DNA; FARNESOID X RECEPTOR; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 77954837070     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0286     Document Type: Article
Times cited : (101)

References (45)
  • 4
    • 0033026760 scopus 로고    scopus 로고
    • Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
    • Wang H, Chen J, Hollister K, Sowers LC, Forman BM 1999 Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol Cell 3:543-553
    • (1999) Mol Cell , vol.3 , pp. 543-553
    • Wang, H.1    Chen, J.2    Hollister, K.3    Sowers, L.C.4    Forman, B.M.5
  • 8
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • DOI 10.1146/annurev.biochem.72.121801.161712
    • Russell DW 2003 The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem 72:137-174 (Pubitemid 36930444)
    • (2003) Annual Review of Biochemistry , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 16
    • 67649208211 scopus 로고    scopus 로고
    • Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice
    • Cui YJ, Aleksunes LM, Tanaka Y, Goedken MJ, Klaassen CD 2009 Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice. Toxicol Sci 110:47-60
    • (2009) Toxicol Sci , vol.110 , pp. 47-60
    • Cui, Y.J.1    Aleksunes, L.M.2    Tanaka, Y.3    Goedken, M.J.4    Klaassen, C.D.5
  • 18
    • 0019943763 scopus 로고
    • Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: Mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine
    • Trudell JR, Bösterling B, Trevor AJ 1982 Reductive metabolism of carbon tetrachloride by human cytochromes P-450 reconstituted in phospholipid vesicles: mass spectral identification of trichloromethyl radical bound to dioleoyl phosphatidylcholine. Proc Natl Acad Sci USA 79:2678-2682
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 2678-2682
    • Trudell, J.R.1    Bösterling, B.2    Trevor, A.J.3
  • 19
    • 0036898019 scopus 로고    scopus 로고
    • Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice
    • Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL 2002 Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. Am J Pathol 161:2003-2010
    • (2002) Am J Pathol , vol.161 , pp. 2003-2010
    • Yu, C.1    Wang, F.2    Jin, C.3    Wu, X.4    Chan, W.K.5    McKeehan, W.L.6
  • 20
    • 0036828271 scopus 로고    scopus 로고
    • Functional expression of the canalicular bile salt export pump of human liver
    • Noé J, Stieger B, Meier PJ 2002 Functional expression of the canalicular bile salt export pump of human liver. Gastroenterology 123:1659-1666 (Pubitemid 35231665)
    • (2002) Gastroenterology , vol.123 , Issue.5 , pp. 1659-1666
    • Noe, J.1    Stieger, B.2    Meier, P.J.3
  • 21
    • 55549144718 scopus 로고    scopus 로고
    • FXR: A metabolic regulator and cell protector
    • Wang YD, Chen WD, Moore DD, Huang W 2008 FXR: a metabolic regulator and cell protector. Cell Res 18:1087-1095
    • (2008) Cell Res , vol.18 , pp. 1087-1095
    • Wang, Y.D.1    Chen, W.D.2    Moore, D.D.3    Huang, W.4
  • 22
    • 56149085041 scopus 로고    scopus 로고
    • Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response
    • Wang YD, Chen WD, Wang M, Yu D, Forman BM, Huang W 2008 Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response. Hepatology 48:1632-1643
    • (2008) Hepatology , vol.48 , pp. 1632-1643
    • Wang, Y.D.1    Chen, W.D.2    Wang, M.3    Yu, D.4    Forman, B.M.5    Huang, W.6
  • 24
    • 53049092599 scopus 로고    scopus 로고
    • E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/ mTOR and COX-2 in a mouse model of human liver cancer
    • Ladu S, Calvisi DF, Conner EA, Farina M, Factor VM, Thorgeirsson SS 2008 E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/ mTOR and COX-2 in a mouse model of human liver cancer. Gastroenterology 135:1322-1332
    • (2008) Gastroenterology , vol.135 , pp. 1322-1332
    • Ladu, S.1    Calvisi, D.F.2    Conner, E.A.3    Farina, M.4    Factor, V.M.5    Thorgeirsson, S.S.6
  • 28
    • 46349098249 scopus 로고    scopus 로고
    • Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo
    • Wang YD, Yang F, Chen WD, Huang X, Lai L, Forman BM, Huang W 2008 Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo. Mol Endocrinol 22:1622-1632
    • (2008) Mol Endocrinol , vol.22 , pp. 1622-1632
    • Wang, Y.D.1    Yang, F.2    Chen, W.D.3    Huang, X.4    Lai, L.5    Forman, B.M.6    Huang, W.7
  • 29
    • 70349559580 scopus 로고    scopus 로고
    • Cholestasis downregulate hepcidin expression through inhibiting IL-6-induced phosphorylation of signal transducer and activator of transcription 3 signaling
    • Huang YH, Chuang JH, Yang YL, Huang CC, Wu CL, Chen CL 2009 Cholestasis downregulate hepcidin expression through inhibiting IL-6-induced phosphorylation of signal transducer and activator of transcription 3 signaling. Lab Invest 89:1128-1139
    • (2009) Lab Invest , vol.89 , pp. 1128-1139
    • Huang, Y.H.1    Chuang, J.H.2    Yang, Y.L.3    Huang, C.C.4    Wu, C.L.5    Chen, C.L.6
  • 30
    • 33750970321 scopus 로고    scopus 로고
    • Bile acids inhibit interleukin-6 signaling via gp130 receptor-dependent and -independent pathways in rat liver
    • Graf D, Kohlmann C, Haselow K, Gehrmann T, Bode JG, Häussinger D 2006 Bile acids inhibit interleukin-6 signaling via gp130 receptor-dependent and -independent pathways in rat liver. Hepatology 44:1206-1217
    • (2006) Hepatology , vol.44 , pp. 1206-1217
    • Graf, D.1    Kohlmann, C.2    Haselow, K.3    Gehrmann, T.4    Bode, J.G.5    Häussinger, D.6
  • 31
    • 1042302005 scopus 로고    scopus 로고
    • The stats of cancer - New molecular targets come of age
    • Yu H, Jove R 2004 The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 4:97-105 (Pubitemid 38198738)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 32
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu F, Song Y, Liu D 1999 Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6:1258-1266
    • (1999) Gene Ther , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 33
    • 0037646504 scopus 로고    scopus 로고
    • Repression of farnesoid X receptor during the acute phase response
    • Kim MS, Shigenaga J, Moser A, Feingold K, Grunfeld C 2003 Repression of farnesoid X receptor during the acute phase response. J Biol Chem 278:8988-8995
    • (2003) J Biol Chem , vol.278 , pp. 8988-8995
    • Kim, M.S.1    Shigenaga, J.2    Moser, A.3    Feingold, K.4    Grunfeld, C.5
  • 36
    • 0024387211 scopus 로고
    • Bile acids inhibit endotoxin- Induced release of tumor necrosis factor by monocytes: An in vitro study
    • Greve JW, Gouma DJ, Buurman WA 1989 Bile acids inhibit endotoxin- induced release of tumor necrosis factor by monocytes: an in vitro study. Hepatology 10:454-458
    • (1989) Hepatology , vol.10 , pp. 454-458
    • Greve, J.W.1    Gouma, D.J.2    Buurman, W.A.3
  • 38
    • 42249088859 scopus 로고    scopus 로고
    • Pregnane X receptor is essential for normal progression of liver regeneration
    • DOI 10.1002/hep.22129
    • Dai G, He L, Bu P, Wan YJ 2008 Pregnane X receptor is essential for normal progression of liver regeneration. Hepatology 47:1277-1287 (Pubitemid 351547914)
    • (2008) Hepatology , vol.47 , Issue.4 , pp. 1277-1287
    • Dai, G.1    He, L.2    Bu, P.3    Wan, Y.-J.Y.4
  • 39
    • 33947667810 scopus 로고    scopus 로고
    • Mechanism of impaired hepatic regeneration in cholestatic liver
    • Yokoyama Y, Nagino M, Nimura Y 2007 Mechanism of impaired hepatic regeneration in cholestatic liver. J Hepatobiliary Pancreat Surg 14:159-166
    • (2007) J Hepatobiliary Pancreat Surg , vol.14 , pp. 159-166
    • Yokoyama, Y.1    Nagino, M.2    Nimura, Y.3
  • 40
    • 32944463507 scopus 로고    scopus 로고
    • Cytokines, STATs and liver disease
    • Gao B 2005 Cytokines, STATs and liver disease. Cell Mol Immunol 2:92-100
    • (2005) Cell Mol Immunol , vol.2 , pp. 92-100
    • Gao, B.1
  • 41
    • 1542724878 scopus 로고    scopus 로고
    • Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice
    • Nakamura K, Nonaka H, Saito H, Tanaka M, Miyajima A 2004 Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice. Hepatology 39:635-644
    • (2004) Hepatology , vol.39 , pp. 635-644
    • Nakamura, K.1    Nonaka, H.2    Saito, H.3    Tanaka, M.4    Miyajima, A.5
  • 42
    • 0029890897 scopus 로고    scopus 로고
    • Expression of leukemia inhibitory factor and its receptor during liver regeneration in the adult rat
    • Omori N, Evarts RP, Omori M, Hu Z, Marsden ER, Thorgeirsson SS 1996 Expression of leukemia inhibitory factor and its receptor during liver regeneration in the adult rat. Lab Invest 75: 15-24 (Pubitemid 26250269)
    • (1996) Laboratory Investigation , vol.75 , Issue.1 , pp. 15-24
    • Omori, N.1    Evarts, R.P.2    Omori, M.3    Hu, Z.4    Marsden, E.R.5    Thorgeirsson, S.S.6
  • 43
    • 58849138857 scopus 로고    scopus 로고
    • Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration
    • Zhang L, Huang X, Meng Z, Dong B, Shiah S, Moore DD, Huang W 2009 Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration. Mol Endocrinol 23: 137-145
    • (2009) Mol Endocrinol , vol.23 , pp. 137-145
    • Zhang, L.1    Huang, X.2    Meng, Z.3    Dong, B.4    Shiah, S.5    Moore, D.D.6    Huang, W.7
  • 44
    • 77950616155 scopus 로고    scopus 로고
    • Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription
    • 22 October, 10.1002/hep23390
    • Chen WD, Wang YD, Zhang L, Shiah S, Wang M, Yang F, Yu D, Forman BM, Huang W 22 October, 2009 Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription. Hepatology 10.1002/hep23390
    • (2009) Hepatology
    • Chen, W.D.1    Wang, Y.D.2    Zhang, L.3    Shiah, S.4    Wang, M.5    Yang, F.6    Yu, D.7    Forman, B.M.8    Huang, W.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.