Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts

Molecular and Cellular Biology

Volumn 32, Issue 19, 2012, Pages 3963-3977

  Nguyen, Christine L ^a,b   Possemato, Richard ^a   Bauerlein, Erica L ^a   Xie, Anyong ^a   Scully, Ralph ^a   Hahn, William C ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE IEPSILON; CELL DIVISION CYCLE 2 PROTEIN; CHECKPOINT KINASE 2; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; DOUBLE STRANDED DNA; HISTONE H2AX; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 11; MESSENGER RNA; NIMA RELATED KINASE 4; PROTEIN; PROTEIN KINASE; PROTEIN P21; PROTEIN P53; RAS PROTEIN; SHORT HAIRPIN RNA; TELOMERASE; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL AGING; CELL CYCLE CHECKPOINTS; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA; DNA DAMAGE; DNA-ACTIVATED PROTEIN KINASE; DOWN-REGULATION; FIBROBLASTS; HUMANS; PROTEIN INTERACTION MAPS; PROTEIN-SERINE-THREONINE KINASES; TELOMERASE; TELOMERE; TRANSCRIPTION, GENETIC;

EID: 84868677342     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00436-12     Document Type: Article

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