Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells

Nucleic Acids Research

Volumn 29, Issue 6, 2001, Pages 1341-1351

  Balajee, A S ^a   Geard, C R ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BLEOMYCIN; BROXURIDINE; CYCLINE; DEOXYRIBONUCLEASE I; DNA; DOUBLE STRANDED DNA; GENE PRODUCT; KU ANTIGEN; SINGLE STRANDED DNA;

ARTICLE; ATAXIA TELANGIECTASIA; CELL NUCLEUS; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; FIBROBLAST CULTURE; GAMMA RADIATION; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RADIATION EXPOSURE; RADIOSENSITIVITY; SALINITY; WESTERN BLOTTING;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0035869118     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.6.1341     Document Type: Article

References (55)

1. Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ
2. Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases δ and ε
3. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
4. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
5. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
6. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase δ holoenzyme
7. Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21
8. Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21
9. Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen
10. Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA
11. Purification of PCNA as a nucleotide excision repair protein
12. Nucleotide excision repair DNA synthesis by DNA polymerase epsilon in the presence of PCNA, RFC and RPA
13. Mammalian DNA nucleotide excision repair reconstituted with purified protein components
14. Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: An alternative pathway of base excision DNA repair
15. Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins
16. Different DNA polymerases are involved in the short-and long-patch base excision repair in mammalian cells
17. The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21
18. Proliferating cell nuclear antigen facilitates excision in long-patch base excision repair
19. Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis
20. PCNA binding proteins
21. Induction of proliferating cell nuclear antigen (PCNA) complex formation in quiescent fibroblasts from a xeroderma pigmentosum patient
22. Detection of nucleotide excision repair incisions in human fibroblasts by immunostaining for PCNA
23. Fine structural analysis of DNA repair in mammalian cells
24. Characterization of X-ray-induced immunostaining of proliferating cell nuclear antigen in human diploid fibroblasts
25. Involvement of the proliferating cell nuclear antigen (PCNA) in DNA repair induced by alkylating agents and oxidative damage in human fibroblasts
26. Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells
27. Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts
28. Proliferating cell nuclear antigen (po130) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins
29. A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair
30. Mutant PCNA alleles are associated with cdc phenotypes and sensitivity to DNA damage in fission yeast
31. Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase δ and DNA polymerase ε
32. Proliferating cell nuclear antigen complex formation induced by ultraviolet irradiation in human quiescent fibroblasts as detected by immunostaining and flow cytometry
33. Biochemical characterization of mouse brain necdin
34. Single cell gel electrophoresis: Detection of DNA damage at different levels of sensitivity
35. Repair of radiation-induced DNA double-strand breaks in human fibroblasts is consistent with a continuous spectrum of repair probability
36. Underestimation of the small residual damage when measuring DNA double-strand breaks (DSB): Is the repair of radiation-induced DSB complete?
37. In vitro rejoining of double strand breaks induced in cellular DNA by bleomycin and restriction endonucleases
38. p53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiation
39. Efficient PCNA complex formation is dependent upon both transcription coupled repair and genome overall repair
40. Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesis
41. Mammalian base excision repair by DNA polymerases δ and ε
42. Nucleotide excision repair of DNA with recombinant human proteins: Definition of the minimal set of factors, active forms of TFIIH and modulation by CAK
43. A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage
44. Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen
45. Induced repair of DNA double-strand breaks at the G1/S-phase border
46. The roles of the eukaryotic DNA polymerases in DNA repair synthesis
47. DNA repair synthesis during base excision repair in vitro is catalyzed by DNA polymerase ε and is influenced by DNA polymerases α and δ in Saccharomyces cerevisiae
48. DNA polymerase δ is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae
49. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
50. A single ataxia telangiectasia gene with a product similar to PI-3 kinase
51. Enhanced phosphorylation of p53 by ATM in response to DNA damage
52. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
53. Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
54. Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
55. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks