Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

Nature

Volumn 432, Issue 7018, 2004, Pages 775-779

  Mao, Jian Hua ^a   Perez Iosada, Jesus ^a   Wu, Di ^a   DelRosario, Reyno ^a   Tsunematsu, Ryosuke ^b   Nakayama, Kelichi I ^b   Brown, Ken ^c   Bryson, Sheila ^c   Balmain, Allan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; DISEASES; RADIATION EFFECTS; SPECTRUM ANALYSIS; TUMORS;

CHROMOSOME STABILITY; FIBROBLASTS; GENE ENCODING; TUMORIGENESIS;

GENES;

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN E; NOTCH RECEPTOR; NOTCH4 RECEPTOR; PROTEIN C JUN; PROTEIN P53; SMALL INTERFERING RNA;

MEDICINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHROMOSOME; CONTROLLED STUDY; DISEASE PREDISPOSITION; EPITHELIUM; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC SCREENING; GENETIC STABILITY; GENETIC STRAIN; GENETIC SUSCEPTIBILITY; HUMAN; LYMPHOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; F-BOX PROTEINS; FEMALE; FIBROBLASTS; GENE DELETION; GENES, TUMOR SUPPRESSOR; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, KNOCKOUT; MUTATION; NEOPLASMS; RNA, MESSENGER; RNA, SMALL INTERFERING; SURVIVAL RATE; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MAMMALIA;

EID: 10644269326     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature03155     Document Type: Article

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