Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells

DNA Repair

Volumn 11, Issue 11, 2012, Pages 864-873

  Korwek, Z ^a   Sewastianik, T ^a   Bielak Zmijewska, A ^a   Mosieniak, G ^a   Alster, O ^a   Moreno Villaneuva, M ^b   Burkle, A ^b   Sikora, E ^a  

^a NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

H2AX; Caspases; DSBs; FADU; KU 55933

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ATM PROTEIN; CASPASE 2; DOUBLE STRANDED DNA; ETOPOSIDE; HISTONE H2AX; PROTEIN P53; PUMA PROTEIN;

APOPTOSIS; ARTICLE; BLOOD SAMPLING; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; ENZYME SUBSTRATE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; CELL CYCLE PROTEINS; CELL PROLIFERATION; DNA; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; ETOPOSIDE; HISTONES; HUMANS; JURKAT CELLS; MORPHOLINES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PYRONES; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84868193873     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.08.006     Document Type: Article

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