-
1
-
-
0036287867
-
DNA topoisomerase II as a target for cancer chemotherapy
-
DOI 10.1081/CNV-120002156
-
JV Walker JL Nitiss 2002 DNA topoisomerase II as a target for cancer chemotherapy Cancer Invest 20 570 589 10.1081/CNV-120002156 12094551 (Pubitemid 34686351)
-
(2002)
Cancer Investigation
, vol.20
, Issue.4
, pp. 570-589
-
-
Walker, J.V.1
Nitiss, J.L.2
-
2
-
-
0032697584
-
Molecular effects of topoisomerase II inhibitors in AML cell lines: Correlation of apoptosis with topoisomerase II activity but not with DNA damage
-
10.1038/sj/leu/2401570 10557063
-
F Gieseler E Bauer V Nuessler M Clark S Valsamas 1999 Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage Leukemia 13 1859 1863 10.1038/sj/leu/2401570 10557063
-
(1999)
Leukemia
, vol.13
, pp. 1859-1863
-
-
Gieseler, F.1
Bauer, E.2
Nuessler, V.3
Clark, M.4
Valsamas, S.5
-
3
-
-
0035130687
-
In vitro topo II-DNA complex accumulation and cytotoxicity of etoposide in leukaemic cells from patients with acute myelogenous and chronic lymphocytic leukaemia
-
DOI 10.1016/S0145-2126(00)00103-X, PII S014521260000103X
-
Y Wang R Zhou J Liliemark A Gruber S Lindemalm F Albertioni E Liliemark 2001 In vitro topo II-DNA complex accumulation and cytotoxicity of etoposide in leukaemic cells from patients with acute myelogenous and chronic lymphocytic leukaemia Leuk Res 25 133 140 10.1016/S0145-2126(00)00103-X 10.1016/S0145- 2126(00)00103-X 11166828 (Pubitemid 32141116)
-
(2001)
Leukemia Research
, vol.25
, Issue.2
, pp. 133-140
-
-
Wang, Y.1
Zhou, R.2
Liliemark, J.3
Gruber, A.4
Lindemalm, S.5
Albertioni, F.6
Liliemark, E.7
-
5
-
-
0035056832
-
Leukemias related to treatment with DNA topoisomerase II inhibitors
-
DOI 10.1002/mpo.1125
-
CA Felix 2001 Leukemias related to treatment with DNA topoisomerase II inhibitors Med Pediatr Oncol 36 525 535 10.1002/mpo.1125 11340607 (Pubitemid 32336557)
-
(2001)
Medical and Pediatric Oncology
, vol.36
, Issue.5
, pp. 525-535
-
-
Felix, C.A.1
-
6
-
-
33747892853
-
Topoisomerase II and the etiology of chromosomal translocations
-
DOI 10.1016/j.dnarep.2006.05.031, PII S1568786406001716, Mechanisms of Chromosomal Translocations
-
CA Felix CP Kolaris N Osheroff 2006 Topoisomerase II and the etiology of chromosomal translocations DNA Repair (Amst) 5 1093 1108 10.1016/j.dnarep.2006. 05.031 10.1016/j.dnarep.2006.05.031 (Pubitemid 44291622)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1093-1108
-
-
Felix, C.A.1
Kolaris, C.P.2
Osheroff, N.3
-
7
-
-
20144388623
-
DNA topoisomerase II in therapy-related acute promyelocytic leukemia
-
DOI 10.1056/NEJMoa042715
-
AR Mistry CA Felix RJ Whitmarsh A Mason A Reiter B Cassinat A Parry C Walz JL Wiemels MR Segal L Ades IA Blair N Osheroff AJ Peniket M Lafage-Pochitaloff NC Cross C Chomienne E Solomon P Fenaux D Grimwade 2005 DNA topoisomerase II in therapy-related acute promyelocytic leukemia N Engl J Med 352 1529 1538 10.1056/NEJMoa042715 15829534 (Pubitemid 40517093)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.15
, pp. 1529-1538
-
-
Mistry, A.R.1
Felix, C.A.2
Whitmarsh, R.J.3
Mason, A.4
Reiter, A.5
Cassinat, B.6
Parry, A.7
Walz, C.8
Wiemels, J.L.9
Segal, M.R.10
Ades, L.11
Blair, I.A.12
Osheroff, N.13
Peniket, A.J.14
Lafage-Pochitaloff, M.15
Cross, N.C.P.16
Chomienne, C.17
Solomon, E.18
Fenaux, P.19
Grimwade, D.20
more..
-
8
-
-
10544232618
-
11q23 aberration is an additional chromosomal change in de novo acute leukemia after treatment with etoposide and mitoxantrone
-
DOI 10.1002/(SICI)1096-8652(199612)53:4<264::AID-AJH12>3.0.CO;2-C
-
A Ohshima I Miura A Chubachi K Hashimoto T Nimura S Utsumi N Takahashi Y Hayashi M Seto R Ueda AB Miura 1996 11q23 aberration is an additional chromosomal change in de novo acute leukemia after treatment with etoposide and mitoxantrone Am J Hematol 53 264 266 10.1002/(SICI)1096-8652(199612)53:4<264: :AID-AJH12>3.0.CO;2-C 8948668 (Pubitemid 26419717)
-
(1996)
American Journal of Hematology
, vol.53
, Issue.4
, pp. 264-266
-
-
Ohshima, A.1
Miura, I.2
Chubachi, A.3
Hashimoto, K.4
Nimura, T.5
Utsumi, S.6
Takahashi, N.7
Hayashi, Y.8
Seto, M.9
Ueda, R.10
Miura, A.B.11
-
9
-
-
0027154575
-
Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation
-
8388919
-
C Sandoval CH Pui LC Bowman D Heaton CA Hurwitz SC Raimondi FG Behm DR Head 1993 Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation J Clin Oncol 11 1039 1045 8388919
-
(1993)
J Clin Oncol
, vol.11
, pp. 1039-1045
-
-
Sandoval, C.1
Pui, C.H.2
Bowman, L.C.3
Heaton, D.4
Hurwitz, C.A.5
Raimondi, S.C.6
Behm, F.G.7
Head, D.R.8
-
10
-
-
0034899185
-
Brief report: Two secondary leukemias among 15 children given oral etoposide
-
DOI 10.1002/mpo.1187
-
A Schiavetti G Varrasso P Maurizi MA Castello 2001 Two secondary leukemias among 15 children given oral etoposide Med Pediatr Oncol 37 148 149 10.1002/mpo.1187 11496357 (Pubitemid 32738080)
-
(2001)
Medical and Pediatric Oncology
, vol.37
, Issue.2
, pp. 148-149
-
-
Schiavetti, A.1
Varrasso, G.2
Maurizi, P.3
Castello, M.A.4
-
11
-
-
33747873409
-
Chromatin structural elements and chromosomal translocations in leukemia
-
DOI 10.1016/j.dnarep.2006.05.020, PII S1568786406001613, Mechanisms of Chromosomal Translocations
-
Y Zhang JD Rowley 2006 Chromatin structural elements and chromosomal translocations in leukemia DNA Repair (Amst) 5 1282 1297 10.1016/j.dnarep.2006. 05.020 10.1016/j.dnarep.2006.05.020 (Pubitemid 44291613)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1282-1297
-
-
Zhang, Y.1
Rowley, J.D.2
-
13
-
-
33847028014
-
Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: Relation to cell cycle phase
-
17297310
-
T Tanaka HD Halicka F Traganos K Seiter Z Darzynkiewicz 2007 Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase Cell Cycle 6 371 376 17297310
-
(2007)
Cell Cycle
, vol.6
, pp. 371-376
-
-
Tanaka, T.1
Halicka, H.D.2
Traganos, F.3
Seiter, K.4
Darzynkiewicz, Z.5
-
14
-
-
35349028340
-
Repair of idarubicin-induced DNA damage: A cause of resistance?
-
DOI 10.1016/j.dnarep.2007.05.007, PII S1568786407002030
-
DC Dartsch F Gieseler 2007 Repair of idarubicin-induced DNA damage: a cause of resistance? DNA Repair (Amst) 6 1618 1628 10.1016/j.dnarep.2007.05.007 10.1016/j.dnarep.2007.05.007 (Pubitemid 47600106)
-
(2007)
DNA Repair
, vol.6
, Issue.11
, pp. 1618-1628
-
-
Dartsch, D.C.1
Gieseler, F.2
-
15
-
-
39149099957
-
Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses
-
10.1016/j.dnarep.2007.12.002 10.1016/j.dnarep.2007.12.002
-
JR Fan AL Peng HC Chen SC Lo TH Huang TK Li 2008 Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses DNA Repair (Amst) 7 452 463 10.1016/j.dnarep.2007.12.002 10.1016/j.dnarep.2007. 12.002
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 452-463
-
-
Fan, J.R.1
Peng, A.L.2
Chen, H.C.3
Lo, S.C.4
Huang, T.H.5
Li, T.K.6
-
16
-
-
9244231805
-
Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway
-
DOI 10.1016/j.yexcr.2004.08.035, PII S0014482704005178
-
J Agner J Falck J Lukas J Bartek 2005 Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway Exp Cell Res 302 162 169 10.1016/j.yexcr.2004.08.035 10.1016/j.yexcr.2004.08.035 15561098 (Pubitemid 39550459)
-
(2005)
Experimental Cell Research
, vol.302
, Issue.2
, pp. 162-169
-
-
Agner, J.1
Falck, J.2
Lukas, J.3
Bartek, J.4
-
17
-
-
70350088548
-
Mechanisms of double-strand break repair in somatic mammalian cells
-
10.1042/BJ20090942 19772495
-
AJ Hartlerode R Scully 2009 Mechanisms of double-strand break repair in somatic mammalian cells Biochem J 423 157 168 10.1042/BJ20090942 19772495
-
(2009)
Biochem J
, vol.423
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
18
-
-
62349103878
-
DNA repair in mammalian cells: DNA double-strand break repair: How to fix a broken relationship
-
10.1007/s00018-009-8740-3 10.1007/s00018-009-8740-3 19153654
-
B Pardo B Gomez-Gonzalez A Aguilera 2009 DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship Cell Mol Life Sci 66 1039 1056 10.1007/s00018-009-8740-3 10.1007/s00018-009-8740-3 19153654
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 1039-1056
-
-
Pardo, B.1
Gomez-Gonzalez, B.2
Aguilera, A.3
-
19
-
-
38049155945
-
Regulation of DNA double-strand break repair pathway choice
-
10.1038/cr.2007.111 10.1038/cr.2007.111 18157161
-
M Shrivastav LP De Haro JA Nickoloff 2008 Regulation of DNA double-strand break repair pathway choice Cell Res 18 134 147 10.1038/cr.2007.111 10.1038/cr.2007.111 18157161
-
(2008)
Cell Res
, vol.18
, pp. 134-147
-
-
Shrivastav, M.1
De Haro, L.P.2
Nickoloff, J.A.3
-
20
-
-
33747889217
-
Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
-
DOI 10.1016/j.dnarep.2006.05.022, PII S1568786406001662, Mechanisms of Chromosomal Translocations
-
E Sonoda H Hochegger A Saberi Y Taniguchi S Takeda 2006 Differential usage of non-homologous end-joining and homologous recombination in double strand break repair DNA Repair (Amst) 5 1021 1029 10.1016/j.dnarep.2006.05.022 10.1016/j.dnarep.2006.05.022 (Pubitemid 44291617)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1021-1029
-
-
Sonoda, E.1
Hochegger, H.2
Saberi, A.3
Taniguchi, Y.4
Takeda, S.5
-
21
-
-
0001501341
-
Expression of the human RAD51 gene during the cell cycle in primary human peripheral blood lymphocytes
-
DOI 10.1016/0167-4889(96)00040-7
-
J Flygare F Benson D Hellgren 1996 Expression of the human RAD51 gene during the cell cycle in primary human peripheral blood lymphocytes Biochim Biophys Acta 1312 231 236 10.1016/0167-4889(96)00040-7 8703992 (Pubitemid 26246521)
-
(1996)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1312
, Issue.3
, pp. 231-236
-
-
Flygare, J.1
Benson, F.2
Hellgren, D.3
-
22
-
-
51849121635
-
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
-
18769152
-
Z Mao M Bozzella A Seluanov V Gorbunova 2008 DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells Cell Cycle 7 2902 2906 18769152
-
(2008)
Cell Cycle
, vol.7
, pp. 2902-2906
-
-
Mao, Z.1
Bozzella, M.2
Seluanov, A.3
Gorbunova, V.4
-
23
-
-
12844278880
-
Rejoining of DNA double-strand breaks as a function of overhang length
-
DOI 10.1128/MCB.25.3.896-906.2005
-
JM Daley TE Wilson 2005 Rejoining of DNA double-strand breaks as a function of overhang length Mol Cell Biol 25 896 906 10.1128/MCB.25.3.896-906. 2005 10.1128/MCB.25.3.896-906.2005 15657419 (Pubitemid 40165799)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.3
, pp. 896-906
-
-
Daley, J.M.1
Wilson, T.E.2
-
25
-
-
2642570858
-
Mechanisms of DNA double strand break repair and chromosome aberration formation
-
DOI 10.1159/000077461
-
G Iliakis H Wang AR Perrault W Boecker B Rosidi F Windhofer W Wu J Guan G Terzoudi G Pantelias 2004 Mechanisms of DNA double strand break repair and chromosome aberration formation Cytogenet Genome Res 104 14 20 10.1159/000077461 10.1159/000077461 15162010 (Pubitemid 38721048)
-
(2004)
Cytogenetic and Genome Research
, vol.104
, Issue.1-4
, pp. 14-20
-
-
Iliakis, G.1
Wang, H.2
Perrault, A.R.3
Boecker, W.4
Rosidi, B.5
Windhofer, F.6
Wu, W.7
Guan, J.8
Terzoudi, G.9
Panteliasc, G.10
-
26
-
-
0035953402
-
Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group
-
DOI 10.1038/sj.onc.1204350
-
H Wang Z-C Zeng T Bui E Sonoda M Takata S Takeda G Iliakis 2001 Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group Oncogene 20 2212 2224 10.1038/sj.onc.1204350 11402316 (Pubitemid 32531279)
-
(2001)
Oncogene
, vol.20
, Issue.18
, pp. 2212-2224
-
-
Wang, H.1
Zeng, Z.-C.2
Bui, T.-A.3
Sonoda, E.4
Takata, M.5
Takeda, S.6
Iliakis, G.7
-
27
-
-
0035339193
-
Growing dictyate oocytes, but not early preimplantation embryos, of the mouse display high levels of DNA homologous recombination by single-strand annealing and lack DNA nonhomologous end joining
-
DOI 10.1006/dbio.2001.0199
-
MT Fiorenza A Bevilacqua S Bevilacqua F Mangia 2001 Growing dictyate oocytes, but not early preimplantation embryos, of the mouse display high levels of DNA homologous recombination by single-strand annealing and lack DNA nonhomologous end joining Dev Biol 233 214 224 10.1006/dbio.2001.0199 11319870 (Pubitemid 32411306)
-
(2001)
Developmental Biology
, vol.233
, Issue.1
, pp. 214-224
-
-
Fiorenza, M.T.1
Bevilacqua, A.2
Bevilacqua, S.3
Mangia, F.4
-
28
-
-
0032859119
-
Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis
-
DOI 10.1038/13821
-
W Goedecke M Eijpe HH Offenberg M van Aalderen C Heyting 1999 Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis Nat Genet 23 194 198 10.1038/13821 10.1038/13821 10508516 (Pubitemid 29455392)
-
(1999)
Nature Genetics
, vol.23
, Issue.2
, pp. 194-198
-
-
Goedecke, W.1
Eijpe, M.2
Offenberg, H.H.3
Van Aalderen, M.4
Heyting, C.5
-
29
-
-
0037371106
-
Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86
-
DOI 10.1095/biolreprod.102.008920
-
G Hamer HL Roepers-Gajadien A van Duyn-Goedhart IS Gademan HB Kal PP van Buul T Ashley DG de Rooij 2003 Function of DNA-protein kinase catalytic subunit during the early meiotic prophase without Ku70 and Ku86 Biol Reprod 68 717 721 10.1095/biolreprod.102.008920 12604618 (Pubitemid 36245813)
-
(2003)
Biology of Reproduction
, vol.68
, Issue.3
, pp. 717-721
-
-
Hamer, G.1
Roepers-Gajadien, H.L.2
Van Duyn-Goedhart, A.3
Gademan, I.S.4
Kal, H.B.5
Van Buul, P.P.W.6
Ashley, T.7
De Rooij, D.G.8
-
30
-
-
0036469066
-
DNA double-strand break repair from head to tail
-
DOI 10.1016/S0959-440X(02)00297-X
-
K Hopfner C Putnam J Tainer 2002 DNA double-strand break repair from head to tail Curr Opin Struct Biol 12 115 122 10.1016/S0959-440X(02)00297-X 10.1016/S0959-440X(02)00297-X 11839498 (Pubitemid 34142729)
-
(2002)
Current Opinion in Structural Biology
, vol.12
, Issue.1
, pp. 115-122
-
-
Hopfner, K.-P.1
Putnam, C.D.2
Tainer, J.A.3
-
31
-
-
0035093737
-
DNA double-strand breaks: Signaling, repair and the cancer connection
-
DOI 10.1038/85798
-
K Khanna S Jackson 2001 DNA double-strand breaks: signaling, repair and the cancer connection Nat Genet 27 247 254 10.1038/85798 10.1038/85798 11242102 (Pubitemid 32201842)
-
(2001)
Nature Genetics
, vol.27
, Issue.3
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
32
-
-
0033594407
-
Binding of double-strand breaks in DNA by human Rad52 protein
-
DOI 10.1038/19560
-
E Van Dyck A Stasiak A Stasiak S West 1999 Binding of double strand breaks in DNA by human Rad52 protein Nature 398 728 731 10.1038/19560 10.1038/19560 10227297 (Pubitemid 29197653)
-
(1999)
Nature
, vol.398
, Issue.6729
, pp. 728-731
-
-
Van Dyck, E.1
Stasiak, A.Z.2
Staslak, A.3
West, S.C.4
-
33
-
-
33748713412
-
Rad54: The Swiss Army knife of homologous recombination?
-
DOI 10.1093/nar/gkl481
-
W-D Heyer X Li M Rolfsmeier X-P Zhang 2006 Rad54: the Swiss army knife of homologous recombination? Nucl Acid Res 34 4115 4125 10.1093/nar/gkl481 10.1093/nar/gkl481 (Pubitemid 44542190)
-
(2006)
Nucleic Acids Research
, vol.34
, Issue.15
, pp. 4115-4125
-
-
Heyer, W.-D.1
Li, X.2
Rolfsmeier, M.3
Zhang, X.-P.4
-
35
-
-
0034502227
-
Crossover clinical study comparing the pharmacokinetics of etoposide (75 mg) administered as 25-mg capsules three times a day versus once a day
-
A Aydiner H Koyuncu F Tas E Topuz R Disci 2000 Crossover clinical study comparing the pharmacokinetics of etoposide (75 mg) administered as 25-mg capsules three times a day versus once a day Int J Clin Pharm Res 20 21 30
-
(2000)
Int J Clin Pharm Res
, vol.20
, pp. 21-30
-
-
Aydiner, A.1
Koyuncu, H.2
Tas, F.3
Topuz, E.4
Disci, R.5
-
37
-
-
0020532855
-
Plasma pharmacokinetics of adriamycin and adriamycinol: Implications for the design of in vitro experiments and treatment protocols
-
6850648
-
R Greene J Collins J Jenkins J Speyer C Myers 1983 Plasma pharmacokinetics of adriamycin and adriamycinol: implications for the design of in vitro experiments and treatment protocols Cancer Res 43 3417 3421 6850648
-
(1983)
Cancer Res
, vol.43
, pp. 3417-3421
-
-
Greene, R.1
Collins, J.2
Jenkins, J.3
Speyer, J.4
Myers, C.5
-
39
-
-
0025200392
-
Pharmacokinetics and metabolism of iodo-doxorubicin and doxorubicin in humans
-
10.1007/BF00280945 2076745
-
K Mross U Mayer K Hamm K Burk D Hossfeld 1990 Pharmacokinetics and metabolism of iodo-doxorubicin and doxorubicin in humans Eur J Clin Pharmacol 39 507 513 10.1007/BF00280945 2076745
-
(1990)
Eur J Clin Pharmacol
, vol.39
, pp. 507-513
-
-
Mross, K.1
Mayer, U.2
Hamm, K.3
Burk, K.4
Hossfeld, D.5
-
40
-
-
0027103045
-
What is the optimal dose and duration of treatment with etoposide ? II. Comparative pharmacokinetic study of three schedules: 1 × 100 mg, 2 × 50 mg, and 4 × 25 mg of oral etoposide daily for 21 days
-
1488657
-
A van der Gaast M Vlastuin T Kok T Splinter 1992 What is the optimal dose and duration of treatment with etoposide ? II. Comparative pharmacokinetic study of three schedules: 1 × 100 mg, 2 × 50 mg, and 4 × 25 mg of oral etoposide daily for 21 days Semin Oncol 19 8 12 1488657
-
(1992)
Semin Oncol
, vol.19
, pp. 8-12
-
-
Van Der Gaast, A.1
Vlastuin, M.2
Kok, T.3
Splinter, T.4
-
41
-
-
1542510121
-
Reduction of TSG101 protein has a negative impact on tumor cell growth
-
DOI 10.1002/ijc.20014
-
G Zhu R Gilchrist N Borley H Chng M Morgan J Marshall R Camplejohn G Muir I Hart 2004 Reduction of TSG101 protein has a negative impact on tumor cell growth Int J Cancer 109 541 547 10.1002/ijc.20014 10.1002/ijc.20014 14991575 (Pubitemid 38339644)
-
(2004)
International Journal of Cancer
, vol.109
, Issue.4
, pp. 541-547
-
-
Zhui, G.1
Gilchrist, R.2
Borley, N.3
Chng, H.W.4
Morgan, M.5
Marshall, J.F.6
Camplejohn, R.S.7
Muir, G.H.8
Hart, I.R.9
-
42
-
-
0036889436
-
Comparison of anthracycline-induced death of human leukemia cells: Programmed cell death versus necrosis
-
DOI 10.1023/A:1020647211557
-
D Dartsch A Schaefer S Boldt W Kolch H Marquardt 2002 Comparison of anthracycline-induced death of human leukemia cells: programmed cell death versus necrosis Apoptosis 7 537 548 10.1023/A:1020647211557 10.1023/A: 1020647211557 12370496 (Pubitemid 35334448)
-
(2002)
Apoptosis
, vol.7
, Issue.6
, pp. 537-548
-
-
Dartsch, D.C.1
Schaefer, A.2
Boldt, S.3
Kolch, W.4
Marquardt, H.5
-
43
-
-
0023919963
-
A simple technique for quantitation of low levels of DNA damage in individual cells
-
10.1016/0014-4827(88)90265-0 10.1016/0014-4827(88)90265-0 3345800
-
N Singh M McCoy R Tice E Schneider 1988 A simple technique for quantitation of low levels of DNA damage in individual cells Exp Cell Res 175 184 191 10.1016/0014-4827(88)90265-0 10.1016/0014-4827(88)90265-0 3345800
-
(1988)
Exp Cell Res
, vol.175
, pp. 184-191
-
-
Singh, N.1
McCoy, M.2
Tice, R.3
Schneider, E.4
-
44
-
-
44649090121
-
The comet assay: Topical issues
-
10.1093/mutage/gem051 18283046
-
AR Collins AA Oscoz G Brunborg I Gaivao L Giovannelli M Kruszewski CC Smith R Stetina 2008 The comet assay: topical issues Mutagenesis 23 143 151 10.1093/mutage/gem051 18283046
-
(2008)
Mutagenesis
, vol.23
, pp. 143-151
-
-
Collins, A.R.1
Oscoz, A.A.2
Brunborg, G.3
Gaivao, I.4
Giovannelli, L.5
Kruszewski, M.6
Smith, C.C.7
Stetina, R.8
-
46
-
-
0021749639
-
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II
-
G Chen L Yang T Rowe B Halligan K Tewey L Liu 1984 Nonintercalative antitumor drugs interfere with the breakage reunion reaction of mammalian DNA topoisomerase II J Biol Chem 259 21 13560 13566 6092381 (Pubitemid 15221834)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.21
, pp. 13560-13566
-
-
Chen, G.L.1
Yang, L.2
Rowe, T.C.3
-
47
-
-
0032168167
-
Etoposide: Four decades of development of a topoisomerase II inhibitor
-
DOI 10.1016/S0959-8049(98)00228-7, PII S0959804998002287
-
K Hande 1998 Etoposide: four decades of development of a topoisomerase II inhibitor Eur J Cancer 34 1514 1521 10.1016/S0959-8049(98)00228-7 10.1016/S0959-8049(98)00228-7 9893622 (Pubitemid 28446331)
-
(1998)
European Journal of Cancer
, vol.34
, Issue.10
, pp. 1514-1521
-
-
Hande, K.R.1
-
48
-
-
1542472979
-
Apoptosis genes and resistance to cancer therapy: What does the experimental and clinical data tell us?
-
14614312
-
JM Brown G Wilson 2003 Apoptosis genes and resistance to cancer therapy: what does the experimental and clinical data tell us? Cancer Biol Ther 2 477 490 14614312
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 477-490
-
-
Brown, J.M.1
Wilson, G.2
-
49
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
10197600
-
JM Brown BG Wouters 1999 Apoptosis, p53, and tumor cell sensitivity to anticancer agents Cancer Res 59 1391 1399 10197600
-
(1999)
Cancer Res
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
50
-
-
34548357031
-
The cisplatin-irradiation combination suggests that apoptosis is not a major determinant of clonogenic death
-
DOI 10.1097/CAD.0b013e328087388f, PII 0000181320070700000005
-
C Lo Nigro E Arnolfo E Taricco A Fruttero EG Russi F Lucio S Ribero A Comino M Merlano S Ungari 2007 The cisplatin-irradiation combination suggests that apoptosis is not a major determinant of clonogenic death Anticancer Drugs 18 659 667 10.1097/CAD.0b013e328087388f 17762394 (Pubitemid 47343658)
-
(2007)
Anti-Cancer Drugs
, vol.18
, Issue.6
, pp. 659-667
-
-
Nigro, C.L.1
Arnolfo, E.2
Taricco, E.3
Fruttero, A.4
Russi, E.G.5
Lucio, F.6
Ribero, S.7
Comino, A.8
Merlano, M.9
Ungari, S.10
-
51
-
-
0142123300
-
Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells
-
DOI 10.1016/S0959-8049(03)00488-X
-
J Russell CC Ling 2003 Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells Eur J Cancer 39 2234 2238 10.1016/S0959-8049(03)00488-X 14522384 (Pubitemid 37297751)
-
(2003)
European Journal of Cancer
, vol.39
, Issue.15
, pp. 2234-2238
-
-
Russell, J.1
Ling, C.C.2
-
52
-
-
0026332184
-
Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression
-
1933888
-
R Bertrand M Sarang J Jenkin D Kerrigan Y Pommier 1991 Differential induction of secondary DNA fragmentation by topoisomerase II inhibitors in human tumor cell lines with amplified c-myc expression Cancer Res 51 6280 6285 1933888
-
(1991)
Cancer Res
, vol.51
, pp. 6280-6285
-
-
Bertrand, R.1
Sarang, M.2
Jenkin, J.3
Kerrigan, D.4
Pommier, Y.5
-
53
-
-
2642643778
-
Intracellular pharmacokinetics of anthracyclines in human leukemia cells: Correlation of DNA-binding with apoptotic cell death
-
9476145
-
F Gieseler V Nussler T Brieden J Kunze S Valsamas 1998 Intracellular pharmacokinetics of anthracyclines in human leukemia cells: correlation of DNA-binding with apoptotic cell death Int J Clin Pharmacol Ther 36 25 28 9476145
-
(1998)
Int J Clin Pharmacol Ther
, vol.36
, pp. 25-28
-
-
Gieseler, F.1
Nussler, V.2
Brieden, T.3
Kunze, J.4
Valsamas, S.5
-
54
-
-
0035029153
-
Tumor cell death induced by topoisomerase-targeting drugs
-
DOI 10.1146/annurev.pharmtox.41.1.53
-
TK Li LF Liu 2001 Tumor cell death induced by topoisomerase-targeting drugs Annu Rev Pharmacol Toxicol 41 53 77 10.1146/annurev.pharmtox.41.1.53 10.1146/annurev.pharmtox.41.1.53 11264450 (Pubitemid 32385882)
-
(2001)
Annual Review of Pharmacology and Toxicology
, vol.41
, pp. 53-77
-
-
Li, T.-K.1
Liu, L.F.2
-
55
-
-
0021864097
-
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide
-
3839166
-
BH Long ST Musial MG Brattain 1985 Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide Cancer Res 45 3106 3112 3839166
-
(1985)
Cancer Res
, vol.45
, pp. 3106-3112
-
-
Long, B.H.1
Musial, S.T.2
Brattain, M.G.3
-
56
-
-
0025317440
-
Mechanism of epipodophyllotoxin-induced cell death in poly(adenosine diphosphate-ribose) synthesis-deficient V79 Chinese hamster cell lines
-
2328496
-
S Chatterjee D Trivedi S Petzold N Berger 1990 Mechanism of epipodophyllotoxin-induced cell death in poly(adenosine diphosphate-ribose) synthesis-deficient V79 Chinese hamster cell lines Cancer Res 50 2713 2718 2328496
-
(1990)
Cancer Res
, vol.50
, pp. 2713-2718
-
-
Chatterjee, S.1
Trivedi, D.2
Petzold, S.3
Berger, N.4
-
57
-
-
33747882412
-
Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: New insights and new questions
-
DOI 10.1016/j.dnarep.2006.05.018, PII S1568786406001595, Mechanisms of Chromosomal Translocations
-
PA Sung J Libura C Richardson 2006 Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions DNA Repair (Amst) 5 1109 1118 10.1016/j.dnarep.2006.05.018 (Pubitemid 44291612)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1109-1118
-
-
Sung, P.A.1
Libura, J.2
Richardson, C.3
-
58
-
-
46749085843
-
Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells
-
10.1016/j.taap.2008.03.001 10.1016/j.taap.2008.03.001 18430445
-
SM Chuang LH Wang JH Hong YW Lin 2008 Induction of Rad51 protein levels by p38 MAPK decreases cytotoxicity and mutagenicity in benzo[a]pyrene-exposed human lung cancer cells Toxicol Appl Pharmacol 230 290 297 10.1016/j.taap.2008. 03.001 10.1016/j.taap.2008.03.001 18430445
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 290-297
-
-
Chuang, S.M.1
Wang, L.H.2
Hong, J.H.3
Lin, Y.W.4
-
59
-
-
0032161902
-
DNA photodamage, repair, gene induction and genotoxicity following exposures to 254 nm UV and 8-methoxypsoralen plus UVA in a eukaryotic cell system
-
10.1111/j.1751-1097.1998.tb09683.x 10.1111/j.1751-1097.1998.tb09683.x 9747584
-
D Averbeck S Averbeck 1998 DNA photodamage, repair, gene induction and genotoxicity following exposures to 254 nm UV and 8-methoxypsoralen plus UVA in a eukaryotic cell system Photochem Photobiol 68 289 295 10.1111/j.1751-1097. 1998.tb09683.x 10.1111/j.1751-1097.1998.tb09683.x 9747584
-
(1998)
Photochem Photobiol
, vol.68
, pp. 289-295
-
-
Averbeck, D.1
Averbeck, S.2
-
60
-
-
0036493227
-
Homologous recombination is essential for RAD51 up-regulation in Saccharomyces cerevisiae following DNA crosslinking damage
-
10.1093/nar/30.5.1224 11861915
-
Y Cohen M Dardalhon D Averbeck 2002 Homologous recombination is essential for RAD51 up-regulation in Saccharomyces cerevisiae following DNA crosslinking damage Nucleic Acids Res 30 1224 1232 10.1093/nar/30.5.1224 11861915
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1224-1232
-
-
Cohen, Y.1
Dardalhon, M.2
Averbeck, D.3
-
61
-
-
42249115685
-
The consequences of Rad51 overexpression for normal and tumor cells
-
10.1016/j.dnarep.2007.12.008 10.1016/j.dnarep.2007.12.008
-
HL Klein 2008 The consequences of Rad51 overexpression for normal and tumor cells DNA Repair (Amst) 7 686 693 10.1016/j.dnarep.2007.12.008 10.1016/j.dnarep.2007.12.008
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 686-693
-
-
Klein, H.L.1
-
62
-
-
0034031137
-
DNA double strand break repair in mammalian cells
-
DOI 10.1016/S0959-437X(00)00069-1
-
P Karran 2000 DNA double strand break repair in mammalian cells Curr Opin Genet Dev 10 144 150 10.1016/S0959-437X(00)00069-1 10.1016/S0959-437X(00)00069- 1 10753787 (Pubitemid 30182246)
-
(2000)
Current Opinion in Genetics and Development
, vol.10
, Issue.2
, pp. 144-150
-
-
Karran, P.1
-
63
-
-
0029763211
-
DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease
-
DOI 10.1074/jbc.271.40.25035
-
Z Han N Malik T Carter WH Reeves JH Wyche EA Hendrickson 1996 DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease J Biol Chem 271 25035 25040 10.1074/jbc.271.40.25035 10.1074/jbc.271.40.25035 8798786 (Pubitemid 26333263)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.40
, pp. 25035-25040
-
-
Han, Z.1
Malik, N.2
Carter, T.3
Reeves, W.H.4
Wyche, J.H.5
Hendrickson, E.A.6
-
65
-
-
0033560796
-
The DNA-dependent protein kinase
-
10.1101/gad.13.8.916 10215620
-
G Smith S Jackson 1999 The DNA-dependent protein kinase Genes Dev 13 916 934 10.1101/gad.13.8.916 10215620
-
(1999)
Genes Dev
, vol.13
, pp. 916-934
-
-
Smith, G.1
Jackson, S.2
-
66
-
-
8944241298
-
DNA-dependent protein kinase catalytic subunit: A target for an ICE-like protease in apoptosis
-
8670824
-
Q Song SP Lees-Miller S Kumar Z Zhang DW Chan GC Smith SP Jackson ES Alnemri G Litwack KK Khanna MF Lavin 1996 DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis EMBO J 15 3238 3246 8670824
-
(1996)
EMBO J
, vol.15
, pp. 3238-3246
-
-
Song, Q.1
Lees-Miller, S.P.2
Kumar, S.3
Zhang, Z.4
Chan, D.W.5
Smith, G.C.6
Jackson, S.P.7
Alnemri, E.S.8
Litwack, G.9
Khanna, K.K.10
Lavin, M.F.11
-
67
-
-
33645524585
-
Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70
-
10.1038/sj.embor.7400622 16440001
-
P Zhu D Zhang D Chowdhury D Martinvalet D Keefe L Shi J Lieberman 2006 Granzyme A, which causes single-stranded DNA damage, targets the double-strand break repair protein Ku70 EMBO Rep 7 431 437 10.1038/sj.embor.7400622 16440001
-
(2006)
EMBO Rep
, vol.7
, pp. 431-437
-
-
Zhu, P.1
Zhang, D.2
Chowdhury, D.3
Martinvalet, D.4
Keefe, D.5
Shi, L.6
Lieberman, J.7
-
68
-
-
29144533365
-
Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis
-
DOI 10.1016/j.yexcr.2005.11.016, PII S001448270500546X
-
V Gama T Yoshida JA Gomez DP Basile LD Mayo AL Haas S Matsuyama 2006 Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis Exp Cell Res 312 488 499 10.1016/j.yexcr.2005.11.016 16368436 (Pubitemid 41804113)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.4
, pp. 488-499
-
-
Gama, V.1
Yoshida, T.2
Gomez, J.A.3
Basile, D.P.4
Mayo, L.D.5
Haas, A.L.6
Matsuyama, S.7
-
69
-
-
0032493889
-
Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage
-
DOI 10.1016/S0092-8674(00)81482-8
-
SE Lee JK Moore A Holmes K Umezu RD Kolodner JE Haber 1998 Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage Cell 94 399 409 10.1016/S0092-8674(00)81482-8 9708741 (Pubitemid 28376083)
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 399-409
-
-
Lee, S.E.1
Moore, J.K.2
Holmes, A.3
Umezu, K.4
Kolodner, R.D.5
Haber, J.E.6
-
70
-
-
34447129653
-
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
-
DOI 10.1038/nsmb1261, PII NSMB1261
-
Y Zhang ML Hefferin L Chen EY Shim HM Tseng Y Kwon P Sung SE Lee AE Tomkinson 2007 Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination Nat Struct Mol Biol 14 639 646 10.1038/nsmb1261 10.1038/nsmb1261 17589524 (Pubitemid 47037068)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.7
, pp. 639-646
-
-
Zhang, Y.1
Hefferin, M.L.2
Chen, L.3
Shim, E.Y.4
Tseng, H.-M.5
Kwon, Y.6
Sung, P.7
Lee, S.E.8
Tomkinson, A.E.9
-
71
-
-
0036864626
-
Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination
-
DOI 10.1016/S1097-2765(02)00705-0
-
M Frank-Vaillant S Marcand 2002 Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination Mol Cell 10 1189 1199 10.1016/S1097-2765(02)00705-0 10.1016/S1097-2765(02)00705-0 12453425 (Pubitemid 35453835)
-
(2002)
Molecular Cell
, vol.10
, Issue.5
, pp. 1189-1199
-
-
Frank-Vaillant, M.1
Marcand, S.2
-
72
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
DOI 10.1038/nature02964
-
G Ira A Pellicioli A Balijja X Wang S Fiorani W Carotenuto G Liberi D Bressan L Wan NM Hollingsworth JE Haber M Foiani 2004 DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1 Nature 431 1011 1017 10.1038/nature02964 10.1038/nature02964 15496928 (Pubitemid 39434425)
-
(2004)
Nature
, vol.431
, Issue.7011
, pp. 1011-1017
-
-
Ira, G.1
Pellicioll, A.2
Balijja, A.3
Wang, X.4
Florani, S.5
Carotenuto, W.6
Liberi, G.7
Bressan, D.8
Wan, L.9
Hollingsworth, N.M.10
Haber, J.E.11
Folani, M.12
|