-
1
-
-
27744496662
-
Animal testing: More than a cosmetic change
-
Abbott, A. (2005). Animal testing: more than a cosmetic change. Nature 438, 144-146.
-
(2005)
Nature
, vol.438
, pp. 144-146
-
-
Abbott, A.1
-
2
-
-
33744782326
-
4-Nitroquinoline 1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species
-
DOI 10.1093/toxsci/kfj161
-
Arima, Y., Nishigori, C., Takeuchi, T., et al. (2006). 4-Nitroquinoline 1-Oxide forms 8-Hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species. Toxicol. Sci. 91, 382-392. (Pubitemid 43827291)
-
(2006)
Toxicological Sciences
, vol.91
, Issue.2
, pp. 382-392
-
-
Arima, Y.1
Nishigori, C.2
Takeuchi, T.3
Oka, S.4
Morimoto, K.5
Utani, A.6
Miyachi, Y.7
-
3
-
-
0344306328
-
Miniaturizing the Comet Assay with 3D Vertical Comets
-
Baert, P. and Van Oostveldt, P. (2003). Miniaturizing the comet assay with 3D vertical comets. Cytrometry A 51, 26-34. (Pubitemid 37517308)
-
(2003)
Cytometry Part A
, vol.51
, Issue.1
, pp. 26-34
-
-
Baert, P.1
Van Oostveldt, P.2
-
4
-
-
25844484034
-
Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro
-
DOI 10.1016/j.mrfmmm.2005.05.001, PII S0027510705002022
-
Baohong, W., Jiliang, H., and Lifen, J. (2005). Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro. Mutat. Res. 578, 149-157. (Pubitemid 41395320)
-
(2005)
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
, vol.578
, Issue.1-2
, pp. 149-157
-
-
Baohong, W.1
Jiliang, H.2
Lifen, J.3
Deqiang, L.4
Wei, Z.5
Jianlin, L.6
Hongping, D.7
-
5
-
-
24044551627
-
The in vivo comet assay: Use and status in genotoxicity testing
-
DOI 10.1093/mutage/gei033
-
Brendler-Schwaab, S., Hartmann, A., Pfuhler, S., and Speit, G. (2005). The in vivo Comet assay: use and status in genotoxicity testing. Mutagenesis 20, 245-254. (Pubitemid 41399464)
-
(2005)
Mutagenesis
, vol.20
, Issue.4
, pp. 245-254
-
-
Brendler-Schwaab, S.1
Hartmann, A.2
Pfuhler, S.3
Speit, G.4
-
6
-
-
25144525484
-
Flow cytometry applications in the evaluation of sperm quality: Semen analysis, sperm function and DNA integrity
-
DOI 10.1016/j.contraception.2005.03.004, PII S0010782405000909
-
Cordelli, E., Eleuteri, P., Leter, G., et al. (2005). Flow cytometry applications in the evaluation of sperm quality: Semen analysis, sperm function and DNA integrity. Contraception 72, 273-279. (Pubitemid 41338109)
-
(2005)
Contraception
, vol.72
, Issue.4
, pp. 273-279
-
-
Cordelli, E.1
Eleuteri, P.2
Leter, G.3
Rescia, M.4
Spano, M.5
-
7
-
-
38449086588
-
ReProComet: A new in vitro method to assess DNA damage in Mammalian sperm
-
DOI 10.1093/toxsci/kfm191
-
Cordelli, E., Fresegna, A. M., D'Alessio, A., et al. (2007). ReProComet: A new in vitro method to assess DNA damage in mammalian sperm. Toxicol. Sci. 99, 545-552. (Pubitemid 351760737)
-
(2007)
Toxicological Sciences
, vol.99
, Issue.2
, pp. 545-552
-
-
Cordelli, E.1
Fresegna, A.M.2
D'alessio, A.3
Eleuteri, P.4
Spano, M.5
Pacchierotti, F.6
Villani, P.7
-
8
-
-
65449153593
-
Nanosized zinc oxide particles induce neural stem cell apoptosis
-
Deng, X., Luan, Q., Chen, W., et al. (2009). Nanosized zinc oxide particles induce neural stem cell apoptosis. Nanotechnology 20, 115101.
-
(2009)
Nanotechnology
, vol.20
, pp. 115101
-
-
Deng, X.1
Luan, Q.2
Chen, W.3
-
9
-
-
77749330769
-
Variation in the measurement of DNA damage by comet assay measured by the ECVAG inter-laboratory validation trial
-
Forchhammer, L., Johansson, C., Loft, S., et al. (2010). Variation in the measurement of DNA damage by comet assay measured by the ECVAG inter-laboratory validation trial. Mutagenesis 25, 113-123.
-
(2010)
Mutagenesis
, vol.25
, pp. 113-123
-
-
Forchhammer, L.1
Johansson, C.2
Loft, S.3
-
10
-
-
0035122936
-
Automatic analysis of slides processed in the Comet assay
-
Frieauff, W., Hartmann, A., and Suter, W. (2001). Automatic analysis of slides processed in the comet assay. Mutagenesis 16, 133-137. (Pubitemid 32184476)
-
(2001)
Mutagenesis
, vol.16
, Issue.2
, pp. 133-137
-
-
Frieauff, W.1
Hartmann, A.2
Suter, W.3
-
11
-
-
34147158989
-
Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: Effect of particle composition
-
DOI 10.1289/ehp.8497
-
Gojova, A., Guo, B., Kota, R. S., et al. (2007). Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: effect of particle composition. Environ. Health Perspect. 115, 403-409. (Pubitemid 46554439)
-
(2007)
Environmental Health Perspectives
, vol.115
, Issue.3
, pp. 403-409
-
-
Gojova, A.1
Guo, B.2
Kota, R.S.3
Rutledge, J.C.4
Kennedy, I.M.5
Barakat, A.I.6
-
12
-
-
20544448220
-
Supplement to the Carcinogenic Potency Database (CPDB): Results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998
-
DOI 10.1093/toxsci/kfi161
-
Gold, L. S., Manley, N. B., Slone, T. H., et al. (2005). Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998. Toxicol. Sci. 85, 747-808. (Pubitemid 40846856)
-
(2005)
Toxicological Sciences
, vol.85
, Issue.2
, pp. 747-808
-
-
Gold, L.S.1
Manley, N.B.2
Slone, T.H.3
Rohrbach, L.4
Garfinkel, G.B.5
-
13
-
-
44749089097
-
Species-specific toxicity of aristolochic acid (AA) in vitro
-
Huljic, S., Bruske, E. I., Pfitzenmaier, N., and Dietrich, D. R. (2008). Species-specific toxicity of aristolochic acid (AA) in vitro. Toxicol. In Vitro 22, 1213-1221.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 1213-1221
-
-
Huljic, S.1
Bruske, E.I.2
Pfitzenmaier, N.3
Dietrich, D.R.4
-
14
-
-
67649233786
-
Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints
-
Jones, K. M., Niaz, M. S., Brooks, C. M., et al. (2009). adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints. Int. J. Environ. Res. Public Health 6, 1124-1144.
-
(2009)
Int. J. Environ. Res. Public Health
, vol.6
, pp. 1124-1144
-
-
Jones, K.M.1
Niaz, M.S.2
Brooks, C.M.3
-
15
-
-
43249103496
-
DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress
-
DOI 10.1128/MCB.01921-07
-
Kappes, F., Fahrer, J., Khodadoust, M. S., et al. (2008). DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress. Mol. Cell Biol. 28, 3245-3257. (Pubitemid 351657089)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.10
, pp. 3245-3257
-
-
Kappes, F.1
Fahrer, J.2
Khodadoust, M.S.3
Tabbert, A.4
Strasser, C.5
Mor-Vaknin, N.6
Moreno-Villanueva, M.7
Burkle, A.8
Markovitz, D.M.9
Ferrando-May, E.10
-
16
-
-
53549086404
-
Copper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubes
-
Karlsson, H. L., Cronholm, P., Gustafsson, J., and Møller, L. (2008). Copper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubes. Chem. Res. Toxicol. 21, 1726-1732.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 1726-1732
-
-
Karlsson, H.L.1
Cronholm, P.2
Gustafsson, J.3
Møller, L.4
-
17
-
-
77957871283
-
The comet assay in nanotoxicology research
-
Karlsson, H. L. (2010). The comet assay in nanotoxicology research. Anal. Bioanal. Chem. 398, 651-666.
-
(2010)
Anal. Bioanal. Chem.
, vol.398
, pp. 651-666
-
-
Karlsson, H.L.1
-
18
-
-
0036150713
-
High throughput Comet assay using 96-well plates
-
Kiskinis, E., Suter, W., and Hartmann, A. (2002). High throughput comet assay using 96-well plates. Mutagenesis 17, 37-43 (Pubitemid 34083384)
-
(2002)
Mutagenesis
, vol.17
, Issue.1
, pp. 37-43
-
-
Kiskinis, E.1
Suter, W.2
Hartmann, A.3
-
19
-
-
37349024831
-
Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21
-
DOI 10.1124/mol.108.039750
-
Kolomeichuk, S. N., Meenakshi Upreti, A. B., Dennis, R. A., et al. (2008). Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1. Mol. Pharmacol. 73, 128-136. (Pubitemid 350294204)
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.1
, pp. 128-136
-
-
Kolomeichuk, S.N.1
Bene, A.2
Upreti, M.3
Dennis, R.A.4
Lyle, C.S.5
Rajasekaran, M.6
Chambers, T.C.7
-
20
-
-
0037424245
-
Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
-
DOI 10.1074/jbc.M210432200
-
Li, N., Ragheb, K., Lawler, G., et al. (2003). Mitochondrial Complex I Inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J. Biol. Chem. 278, 8516-8525. (Pubitemid 36800604)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.10
, pp. 8516-8525
-
-
Li, N.1
Ragheb, K.2
Lawler, G.3
Sturgis, J.4
Rajwa, B.5
Melendez, J.A.6
Robinson, J.P.7
-
21
-
-
58149185440
-
Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells
-
Lin, W., Xu, Y., Huang, C., et al. (2009). Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells. Nanopart. Res. 11, 25-39.
-
(2009)
Nanopart. Res.
, vol.11
, pp. 25-39
-
-
Lin, W.1
Xu, Y.2
Huang, C.3
-
22
-
-
0033492999
-
Apoptosis induced by ã-irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases
-
DOI 10.1006/cbir.1999.0429
-
Louagie, H., Schotte, P., Vral, A., et al. (1999). Apoptosis induced by ã-irradiation in peripheral blood mononuclear cells is not mediated by citochrome-c release and only partially involves caspase-3-like proteases. Cell Biol. Int. 23, 611-617. (Pubitemid 30125210)
-
(1999)
Cell Biology International
, vol.23
, Issue.9
, pp. 611-617
-
-
Louagie, H.1
Schotte, P.2
Vral, A.3
Cornelissen, M.4
Thierens, H.5
Beyaert, R.6
De Ridder, L.7
Philippe, J.8
-
23
-
-
77955057498
-
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
-
Mangerich, A., Herbach, N., Hanf, B., et al. (2010). Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. Mech. Ageing Dev. 131, 390-404.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 390-404
-
-
Mangerich, A.1
Herbach, N.2
Hanf, B.3
-
24
-
-
32344448694
-
Assessment of reference values for DNA damage detected by the comet assay in humans blood cells DNA
-
Møller, P. (2006). Assessment of reference values for DNA damage detected by the comet assay in humans blood cells DNA. Mutat. Res. 612, 84-104.
-
(2006)
Mutat. Res.
, vol.612
, pp. 84-104
-
-
Møller, P.1
-
25
-
-
77749323398
-
Assessment and reduction of comet assay variation in relation to DNA damage: Studies from the European Comet Assay Validation Group
-
Møller, P., Möller, L., Godschalk, R. W., and Jones, G. D. (2010). Assessment and reduction of comet assay variation in relation to DNA damage: studies from the European Comet Assay Validation Group. Mutagenesis 25, 109-111.
-
(2010)
Mutagenesis
, vol.25
, pp. 109-111
-
-
Møller, P.1
Möller, L.2
Godschalk, R.W.3
Jones, G.D.4
-
26
-
-
34248356003
-
Cellular response to etoposide treatment
-
DOI 10.1016/j.canlet.2006.11.005, PII S0304383506006227
-
Montecucco, A. and Biamonti, G. (2006). Cellular response to etoposide treatment. Cancer Lett. 252, 9-18. (Pubitemid 46734551)
-
(2007)
Cancer Letters
, vol.252
, Issue.1
, pp. 9-18
-
-
Montecucco, A.1
Biamonti, G.2
-
27
-
-
77951230643
-
ZnO particulate matter requires cell contact for toxicity in human colon cancer cells
-
Moos, P. J., Chung, K., Woessner, D., et al. (2010). ZnO particulate matter requires cell contact for toxicity in human colon cancer cells. Chem. Res. Toxicol. 23, 733-739.
-
(2010)
Chem. Res. Toxicol.
, vol.23
, pp. 733-739
-
-
Moos, P.J.1
Chung, K.2
Woessner, D.3
-
28
-
-
65549163171
-
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks
-
Moreno-Villanueva, M., Pfeiffer, R., Sindlinger, T., et al. (2009). A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks. BMC Biotechnol. 9, 39.
-
(2009)
BMC Biotechnol.
, vol.9
, pp. 39
-
-
Moreno-Villanueva, M.1
Pfeiffer, R.2
Sindlinger, T.3
-
29
-
-
33645839303
-
UVA-induced apoptosis studied by the new apo/necro-comet-assay which distinguishes viable, apoptotic and necrotic cells
-
Morley, N., Rapp, A., Dittmar, H., et al. (2006). UVA-induced apoptosis studied by the new apo/necro-comet-assay which distinguishes viable, apoptotic and necrotic cells. Mutagenesis 21, 105-114.
-
(2006)
Mutagenesis
, vol.21
, pp. 105-114
-
-
Morley, N.1
Rapp, A.2
Dittmar, H.3
-
30
-
-
0001329281
-
Carcinogenic action of 4-nitroquinoline-N-oxide
-
Nakahara, W., Fukuoka, F., and Sugimura, T. (1957). Carcinogenic action of 4-nitroquinoline-N-oxide. Gann. 48, 129-137.
-
(1957)
Gann.
, vol.48
, pp. 129-137
-
-
Nakahara, W.1
Fukuoka, F.2
Sugimura, T.3
-
31
-
-
34250654965
-
The comet assay: A method to measure DNA damage in individual cells
-
Olive, P. L. and Banáth, J. P. (2006). The comet assay: a method to measure DNA damage in individual cells. Nat. Protoc. 1, 23-29.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 23-29
-
-
Olive, P.L.1
Banáth, J.P.2
-
32
-
-
0029923972
-
Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends
-
DOI 10.1074/jbc.271.47.29807
-
Panda, D., Jordan, M. A., Chin Chu, K., and Wilson, L. (1996). Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends. J. Biol. Chem. 271, 29807-29812. (Pubitemid 26389611)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.47
, pp. 29807-29812
-
-
Panda, D.1
Jordan, M.A.2
Chu, K.C.3
Wilson, L.4
-
33
-
-
84455186983
-
Genotoxicity testing: A critical review of current approaches and risk assessment abstracts
-
Parry, J. M. (2006). Genotoxicity testing: A critical review of current approaches and risk assessment abstracts. Toxicology 226, 12-77.
-
(2006)
Toxicology
, vol.226
, pp. 12-77
-
-
Parry, J.M.1
-
34
-
-
0030826929
-
Topoisomerase I inhibitors: Review and update
-
Rothenberg, M. L. (1997). Topoisomerase I inhibitors: Review and update. Ann. Oncol. 8, 837-855.
-
(1997)
Ann. Oncol.
, vol.8
, pp. 837-855
-
-
Rothenberg, M.L.1
-
35
-
-
78650509723
-
Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles
-
Song, W., Zhang, J., Guo, J., et al. (2010). Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol. Lett. 199, 389.
-
(2010)
Toxicol. Lett.
, vol.199
, pp. 389
-
-
Song, W.1
Zhang, J.2
Guo, J.3
-
36
-
-
34347229468
-
Genetic toxicity assessment: Employing the best science for human safety evaluation part III: The comet assay as an alternative to in vitro clastogenicity tests for early drug candidate selection
-
DOI 10.1093/toxsci/kfl192
-
Witte, I., Plappert, U., de Wall, H., and Hartmann, A. (2007). Genetic toxicity assessment: employing the best science for human safety evaluation part III: the comet assay as an alternative to in vitro clastogenicity tests for early drug candidate selection. Toxicol. Sci. 97, 21-26. (Pubitemid 47072151)
-
(2007)
Toxicological Sciences
, vol.97
, Issue.1
, pp. 21-26
-
-
Witte, I.1
Plappert, U.2
De Wall, H.3
Hartmann, A.4
-
37
-
-
77953371612
-
Single cell trapping and DNA damage analysis using microwell arrays
-
Wooda, D. K., Weingeist, D. M., Bhatiaa, S. N., and Engelward, B. P. (2010). Single cell trapping and DNA damage analysis using microwell arrays. Proc. Natl. Acad. Sci. USA 107, 10008-10013.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 10008-10013
-
-
Wooda, D.K.1
Weingeist, D.M.2
Bhatiaa, S.N.3
Engelward, B.P.4
-
38
-
-
33845726097
-
Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks
-
DOI 10.1021/tx060164e
-
Wyatt, M. D. and Pittman, D. L. (2006). Methylating agents and DNA repair responses: Methylated bases and sources of strand breaks. Chem. Res. Toxicol. 19, 1580-1594. (Pubitemid 44975121)
-
(2006)
Chemical Research in Toxicology
, vol.19
, Issue.12
, pp. 1580-1594
-
-
Wyatt, M.D.1
Pittman, D.L.2
-
39
-
-
56049106549
-
Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties
-
Xia, T., Kovochich, M., Liong, M., et al. (2008). Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano. 2, 2121.
-
(2008)
ACS Na
, vol.2
, pp. 2121
-
-
Xia, T.1
Kovochich, M.2
Liong, M.3
-
40
-
-
0026778383
-
Mechanism of action of hydroxyurea
-
Yarbro, J. W. (1992). Mechanism of action of hydroxyurea. Semin. Oncol. 19, 1-10.
-
(1992)
Semin. Oncol.
, vol.19
, pp. 1-10
-
-
Yarbro, J.W.1
|