-
1
-
-
79957896454
-
Wnt signaling escapes to cilia
-
Ajima R., Hamada H. Wnt signaling escapes to cilia. Nat. Cell Biol. 2011, 13:636-637.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 636-637
-
-
Ajima, R.1
Hamada, H.2
-
2
-
-
33847126689
-
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
-
Asselin-Labat M.L., Sutherland K.D., Barker H., Thomas R., Shackleton M., Forrest N.C., Hartley L., Robb L., Grosveld F.G., van der Wees J., Lindeman G.J., Visvader J.E. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nat. Cell Biol. 2007, 9:201-209.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 201-209
-
-
Asselin-Labat, M.L.1
Sutherland, K.D.2
Barker, H.3
Thomas, R.4
Shackleton, M.5
Forrest, N.C.6
Hartley, L.7
Robb, L.8
Grosveld, F.G.9
van der Wees, J.10
Lindeman, G.J.11
Visvader, J.E.12
-
3
-
-
0036801765
-
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
-
Bai C.B., Auerbach W., Lee J.S., Stephen D., Joyner A.L. Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 2002, 129:4753-4761.
-
(2002)
Development
, vol.129
, pp. 4753-4761
-
-
Bai, C.B.1
Auerbach, W.2
Lee, J.S.3
Stephen, D.4
Joyner, A.L.5
-
4
-
-
70349974840
-
Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer
-
Bailey J.M., Mohr A.M., Hollingsworth M.A. Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer. Oncogene 2009, 28:3513-3525.
-
(2009)
Oncogene
, vol.28
, pp. 3513-3525
-
-
Bailey, J.M.1
Mohr, A.M.2
Hollingsworth, M.A.3
-
5
-
-
9244221172
-
Tissue repair and stem cell renewal in carcinogenesis
-
Beachy P.A., Karhadkar S.S., Berman D.M. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004, 432:324-331.
-
(2004)
Nature
, vol.432
, pp. 324-331
-
-
Beachy, P.A.1
Karhadkar, S.S.2
Berman, D.M.3
-
6
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman D.M., Karhadkar S.S., Maitra A., Montes De Oca R., Gerstenblith M.R., Briggs K., Parker A.R., Shimada Y., Eshleman J.R., Watkins D.N., Beachy P.A. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003, 425:846-851.
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
7
-
-
0036278690
-
Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept
-
Bocker W., Moll R., Poremba C., Holland R., Van Diest P.J., Dervan P., Burger H., Wai D., Ina Diallo R., Brandt B., Herbst H., Schmidt A., Lerch M.M., Buchwallow I.B. Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept. Lab. Invest. 2002, 82:737-746.
-
(2002)
Lab. Invest.
, vol.82
, pp. 737-746
-
-
Bocker, W.1
Moll, R.2
Poremba, C.3
Holland, R.4
Van Diest, P.J.5
Dervan, P.6
Burger, H.7
Wai, D.8
Ina Diallo, R.9
Brandt, B.10
Herbst, H.11
Schmidt, A.12
Lerch, M.M.13
Buchwallow, I.B.14
-
8
-
-
13244273440
-
Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-Β1 expression
-
Boulanger C.A., Wagner K.U., Smith G.H. Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-Β1 expression. Oncogene 2005, 24:552-560.
-
(2005)
Oncogene
, vol.24
, pp. 552-560
-
-
Boulanger, C.A.1
Wagner, K.U.2
Smith, G.H.3
-
9
-
-
80055061033
-
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer
-
Bu W., Chen J., Morrison G.D., Huang S., Creighton C.J., Huang J., Chamness G.C., Hilsenbeck S.G., Roop D.R., Leavitt A.D., Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene 2011.
-
(2011)
Oncogene
-
-
Bu, W.1
Chen, J.2
Morrison, G.D.3
Huang, S.4
Creighton, C.J.5
Huang, J.6
Chamness, G.C.7
Hilsenbeck, S.G.8
Roop, D.R.9
Leavitt, A.D.10
Li, Y.11
-
11
-
-
34248665259
-
Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia
-
Celis J.E., Moreira J.M., Gromova I., Cabezon T., Gromov P., Shen T., Timmermans V., Rank F. Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol. Oncol. 2007, 1:97-119.
-
(2007)
Mol. Oncol.
, vol.1
, pp. 97-119
-
-
Celis, J.E.1
Moreira, J.M.2
Gromova, I.3
Cabezon, T.4
Gromov, P.5
Shen, T.6
Timmermans, V.7
Rank, F.8
-
12
-
-
77953389464
-
Primary cilia regulate Gli/hedgehog activation in pancreas
-
Cervantes S., Lau J., Cano D.A., BorromeoAustin C., Hebrok M. Primary cilia regulate Gli/hedgehog activation in pancreas. Proc. Natl. Acad. Sci. USA 2010, 107:10109-10114.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 10109-10114
-
-
Cervantes, S.1
Lau, J.2
Cano, D.A.3
BorromeoAustin, C.4
Hebrok, M.5
-
13
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G., Abdallah W.M., Foley J.M., Jackson K.W., Clarke M.F., Kawamura M.J., Wicha M.S. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003, 17:1253-1270.
-
(2003)
Genes Dev.
, vol.17
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
14
-
-
0021931794
-
Risk factors for breast cancer in women with proliferative breast disease
-
Dupont W.D., Page D.L. Risk factors for breast cancer in women with proliferative breast disease. N. Engl. J. Med. 1985, 312:146-151.
-
(1985)
N. Engl. J. Med.
, vol.312
, pp. 146-151
-
-
Dupont, W.D.1
Page, D.L.2
-
15
-
-
66349097441
-
Development of mammary tumors by conditional expression of GLI1
-
Fiaschi M., Rozell B., Bergstrom A., Toftgard R. Development of mammary tumors by conditional expression of GLI1. Cancer Res. 2009, 69:4810-4817.
-
(2009)
Cancer Res.
, vol.69
, pp. 4810-4817
-
-
Fiaschi, M.1
Rozell, B.2
Bergstrom, A.3
Toftgard, R.4
-
16
-
-
37249034086
-
Targeted expression of GLI1 in the mammary gland disrupts pregnancy-induced maturation and causes lactation failure
-
Fiaschi M., Rozell B., Bergstrom A., Toftgard R., Kleman M.I. Targeted expression of GLI1 in the mammary gland disrupts pregnancy-induced maturation and causes lactation failure. J. Biol. Chem. 2007, 282:36090-36101.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36090-36101
-
-
Fiaschi, M.1
Rozell, B.2
Bergstrom, A.3
Toftgard, R.4
Kleman, M.I.5
-
17
-
-
0036382665
-
Differential requirements for shh in mammary tissue and hair follicle morphogenesis
-
Gallego M.I., Beachy P.A., Hennighausen L., Robinson G.W. Differential requirements for shh in mammary tissue and hair follicle morphogenesis. Dev. Biol. 2002, 249:131-139.
-
(2002)
Dev. Biol.
, vol.249
, pp. 131-139
-
-
Gallego, M.I.1
Beachy, P.A.2
Hennighausen, L.3
Robinson, G.W.4
-
18
-
-
0346122895
-
Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways
-
Gallego M.I., Bierie B., Hennighausen L. Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways. Oncogene 2003, 22:8498-8508.
-
(2003)
Oncogene
, vol.22
, pp. 8498-8508
-
-
Gallego, M.I.1
Bierie, B.2
Hennighausen, L.3
-
19
-
-
77953662946
-
The primary cilium as a Hedgehog signal transduction machine
-
Goetz S.C., Ocbina P.J., Anderson K.V. The primary cilium as a Hedgehog signal transduction machine. Methods Cell Biol. 2009, 94:199-222.
-
(2009)
Methods Cell Biol.
, vol.94
, pp. 199-222
-
-
Goetz, S.C.1
Ocbina, P.J.2
Anderson, K.V.3
-
20
-
-
0030866154
-
Altered neural cell fates and medulloblastoma in mouse patched mutants
-
Goodrich L.V., Milenkovic L., Higgins K.M., Scott M.P. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 1997, 277:1109-1113.
-
(1997)
Science
, vol.277
, pp. 1109-1113
-
-
Goodrich, L.V.1
Milenkovic, L.2
Higgins, K.M.3
Scott, M.P.4
-
21
-
-
33747122721
-
Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia
-
Gudjonsson T., Adriance M.C., Sternlicht M.D., Petersen O.W., Bissell M.J. Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia. J. Mammary Gland Biol. Neoplasia 2005, 10:261-272.
-
(2005)
J. Mammary Gland Biol. Neoplasia
, vol.10
, pp. 261-272
-
-
Gudjonsson, T.1
Adriance, M.C.2
Sternlicht, M.D.3
Petersen, O.W.4
Bissell, M.J.5
-
22
-
-
34547693211
-
Hedgehog signaling in mammary gland development and breast cancer
-
Hatsell S., Frost A.R. Hedgehog signaling in mammary gland development and breast cancer. J. Mammary Gland Biol. Neoplasia 2007, 12:163-173.
-
(2007)
J. Mammary Gland Biol. Neoplasia
, vol.12
, pp. 163-173
-
-
Hatsell, S.1
Frost, A.R.2
-
23
-
-
33750372746
-
Gli3-mediated repression of Hedgehog targets is required for normal mammary development
-
Hatsell S.J., Cowin P. Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development 2006, 133:3661-3670.
-
(2006)
Development
, vol.133
, pp. 3661-3670
-
-
Hatsell, S.J.1
Cowin, P.2
-
24
-
-
40749144679
-
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
-
Haycraft C.J., Banizs B., Aydin-Son Y., Zhang Q., Michaud E.J., Yoder B.K. Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet. 2005, 1:e53.
-
(2005)
PLoS Genet.
, vol.1
-
-
Haycraft, C.J.1
Banizs, B.2
Aydin-Son, Y.3
Zhang, Q.4
Michaud, E.J.5
Yoder, B.K.6
-
25
-
-
0035489712
-
Signaling pathways in mammary gland development
-
Hennighausen L., Robinson G.W. Signaling pathways in mammary gland development. Dev. Cell 2001, 1:467-475.
-
(2001)
Dev. Cell
, vol.1
, pp. 467-475
-
-
Hennighausen, L.1
Robinson, G.W.2
-
26
-
-
23844485210
-
Cilia and Hedgehog responsiveness in the mouse
-
Huangfu D., Anderson K.V. Cilia and Hedgehog responsiveness in the mouse. Proc. Natl. Acad. Sci. USA 2005, 102:11325-11330.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11325-11330
-
-
Huangfu, D.1
Anderson, K.V.2
-
27
-
-
0242581681
-
Hedgehog signaling in the mouse requires intraflagellar transport proteins
-
Huangfu D., Liu A., Rakeman A.S., Murcia N.S., Niswander L., Anderson K.V. Hedgehog signaling in the mouse requires intraflagellar transport proteins. Nature 2003, 426:83-87.
-
(2003)
Nature
, vol.426
, pp. 83-87
-
-
Huangfu, D.1
Liu, A.2
Rakeman, A.S.3
Murcia, N.S.4
Niswander, L.5
Anderson, K.V.6
-
28
-
-
0035577854
-
Hedgehog signaling in animal development: paradigms and principles
-
Ingham P.W., McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 2001, 15:3059-3087.
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
29
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang J., Hui C.C. Hedgehog signaling in development and cancer. Dev. Cell 2008, 15:801-812.
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
30
-
-
6044243650
-
Hedgehog signaling in prostate regeneration, neoplasia and metastasis
-
Karhadkar S.S., Bova G.S., Abdallah N., Dhara S., Gardner D., Maitra A., Isaacs J.T., Berman D.M., Beachy P.A. Hedgehog signaling in prostate regeneration, neoplasia and metastasis. Nature 2004, 431:707-712.
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
31
-
-
79953331186
-
Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry
-
Kim S., Zaghloul N.A., Bubenshchikova E., Oh E.C., Rankin S., Katsanis N., Obara T., Tsiokas L. Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry. Nat. Cell Biol. 2011, 13:351-360.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 351-360
-
-
Kim, S.1
Zaghloul, N.A.2
Bubenshchikova, E.3
Oh, E.C.4
Rankin, S.5
Katsanis, N.6
Obara, T.7
Tsiokas, L.8
-
32
-
-
84860390440
-
Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential
-
Kittrell F.S., Carletti M.Z., Kerbawy S., Heestand J., Xian W., Zhang M., Lamarca H.L., Sonnenberg A., Rosen J.M., Medina D., Behbod F. Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res. 2011, 13:R41.
-
(2011)
Breast Cancer Res.
, vol.13
-
-
Kittrell, F.S.1
Carletti, M.Z.2
Kerbawy, S.3
Heestand, J.4
Xian, W.5
Zhang, M.6
Lamarca, H.L.7
Sonnenberg, A.8
Rosen, J.M.9
Medina, D.10
Behbod, F.11
-
33
-
-
0028986768
-
Ectopic TGF Β 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population
-
Kordon E.C., McKnight R.A., Jhappan C., Hennighausen L., Merlino G., Smith G.H. Ectopic TGF Β 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population. Dev. Biol. 1995, 168:47-61.
-
(1995)
Dev. Biol.
, vol.168
, pp. 47-61
-
-
Kordon, E.C.1
McKnight, R.A.2
Jhappan, C.3
Hennighausen, L.4
Merlino, G.5
Smith, G.H.6
-
34
-
-
33751235462
-
Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis
-
Kouros-Mehr H., Werb Z. Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis. Dev. Dyn. 2006, 235:3404-3412.
-
(2006)
Dev. Dyn.
, vol.235
, pp. 3404-3412
-
-
Kouros-Mehr, H.1
Werb, Z.2
-
35
-
-
80054743186
-
Elevated Hedgehog/Gli signaling causes {Β}-cell dedifferentiation in mice
-
Landsman L., Parent A., Hebrok M. Elevated Hedgehog/Gli signaling causes {Β}-cell dedifferentiation in mice. Proc. Natl. Acad. Sci. USA 2011, 108:17010-17015.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17010-17015
-
-
Landsman, L.1
Parent, A.2
Hebrok, M.3
-
36
-
-
77951835156
-
Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult Β-cell function
-
Lau J., Hebrok M. Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult Β-cell function. Diabetes 2010, 59:1211-1221.
-
(2010)
Diabetes
, vol.59
, pp. 1211-1221
-
-
Lau, J.1
Hebrok, M.2
-
37
-
-
0033404514
-
Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1
-
Lewis M.T., Ross S., Strickland P.A., Sugnet C.W., Jimenez E., Scott M.P., Daniel C.W. Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development 1999, 126:5181-5193.
-
(1999)
Development
, vol.126
, pp. 5181-5193
-
-
Lewis, M.T.1
Ross, S.2
Strickland, P.A.3
Sugnet, C.W.4
Jimenez, E.5
Scott, M.P.6
Daniel, C.W.7
-
38
-
-
0035477629
-
The Gli2 transcription factor is required for normal mouse mammary gland development
-
Lewis M.T., Ross S., Strickland P.A., Sugnet C.W., Jimenez E., Hui C., Daniel C.W. The Gli2 transcription factor is required for normal mouse mammary gland development. Dev. Biol. 2001, 238:133-144.
-
(2001)
Dev. Biol.
, vol.238
, pp. 133-144
-
-
Lewis, M.T.1
Ross, S.2
Strickland, P.A.3
Sugnet, C.W.4
Jimenez, E.5
Hui, C.6
Daniel, C.W.7
-
39
-
-
47949105620
-
Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells
-
Li N., Singh S., Cherukuri P., Li H., Yuan Z., Ellisen L.W., Wang B., Robbins D., DiRenzo J. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells 2008, 26:1253-1264.
-
(2008)
Stem Cells
, vol.26
, pp. 1253-1264
-
-
Li, N.1
Singh, S.2
Cherukuri, P.3
Li, H.4
Yuan, Z.5
Ellisen, L.W.6
Wang, B.7
Robbins, D.8
DiRenzo, J.9
-
40
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S., Dontu G., Mantle I.D., Patel S., Ahn N.S., Jackson K.W., Suri P., Wicha M.S. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 2006, 66:6063-6071.
-
(2006)
Cancer Res.
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.S.5
Jackson, K.W.6
Suri, P.7
Wicha, M.S.8
-
41
-
-
77952165223
-
Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract
-
Mao J., Kim B.M., Rajurkar M., Shivdasani R.A., McMahon A.P. Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development 2010, 137:1721-1729.
-
(2010)
Development
, vol.137
, pp. 1721-1729
-
-
Mao, J.1
Kim, B.M.2
Rajurkar, M.3
Shivdasani, R.A.4
McMahon, A.P.5
-
42
-
-
77951204905
-
Primary cilia regulate branching morphogenesis during mammary gland development
-
McDermott K.M., Liu B.Y., Tlsty T.D., Pazour G.J. Primary cilia regulate branching morphogenesis during mammary gland development. Curr. Biol. 2010, 20:731-737.
-
(2010)
Curr. Biol.
, vol.20
, pp. 731-737
-
-
McDermott, K.M.1
Liu, B.Y.2
Tlsty, T.D.3
Pazour, G.J.4
-
43
-
-
0242539939
-
Shh expression is required for embryonic hair follicle but not mammary gland development
-
Michno K., Boras-Granic K., Mill P., Hui C.C., Hamel P.A. Shh expression is required for embryonic hair follicle but not mammary gland development. Dev. Biol. 2003, 264:153-165.
-
(2003)
Dev. Biol.
, vol.264
, pp. 153-165
-
-
Michno, K.1
Boras-Granic, K.2
Mill, P.3
Hui, C.C.4
Hamel, P.A.5
-
44
-
-
31144451362
-
Expression of terminal differentiation proteins defines stages of mouse mammary gland development
-
Mikaelian I., Hovick M., Silva K.A., Burzenski L.M., Shultz L.D., Ackert-Bicknell C.L., Cox G.A., Sundberg J.P. Expression of terminal differentiation proteins defines stages of mouse mammary gland development. Vet. Pathol. 2006, 43:36-49.
-
(2006)
Vet. Pathol.
, vol.43
, pp. 36-49
-
-
Mikaelian, I.1
Hovick, M.2
Silva, K.A.3
Burzenski, L.M.4
Shultz, L.D.5
Ackert-Bicknell, C.L.6
Cox, G.A.7
Sundberg, J.P.8
-
45
-
-
0037103985
-
Activation of different Wnt/Β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors
-
Miyoshi K., Rosner A., Nozawa M., Byrd C., Morgan F., Landesman-Bollag E., Xu X., Seldin D.C., Schmidt E.V., Taketo M.M., Robinson G.W., Cardiff R.D., Hennighausen L. Activation of different Wnt/Β-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors. Oncogene 2002, 21:5548-5556.
-
(2002)
Oncogene
, vol.21
, pp. 5548-5556
-
-
Miyoshi, K.1
Rosner, A.2
Nozawa, M.3
Byrd, C.4
Morgan, F.5
Landesman-Bollag, E.6
Xu, X.7
Seldin, D.C.8
Schmidt, E.V.9
Taketo, M.M.10
Robinson, G.W.11
Cardiff, R.D.12
Hennighausen, L.13
-
46
-
-
67649225569
-
Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation
-
Moraes R.C., Chang H., Harrington N., Landua J.D., Prigge J.T., Lane T.F., Wainwright B.J., Hamel P.A., Lewis M.T. Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation. Development 2009, 136:1423-1432.
-
(2009)
Development
, vol.136
, pp. 1423-1432
-
-
Moraes, R.C.1
Chang, H.2
Harrington, N.3
Landua, J.D.4
Prigge, J.T.5
Lane, T.F.6
Wainwright, B.J.7
Hamel, P.A.8
Lewis, M.T.9
-
47
-
-
34247398806
-
Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
-
Moraes R.C., Zhang X., Harrington N., Fung J.Y., Wu M.F., Hilsenbeck S.G., Allred D.C., Lewis M.T. Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 2007, 134:1231-1242.
-
(2007)
Development
, vol.134
, pp. 1231-1242
-
-
Moraes, R.C.1
Zhang, X.2
Harrington, N.3
Fung, J.Y.4
Wu, M.F.5
Hilsenbeck, S.G.6
Allred, D.C.7
Lewis, M.T.8
-
48
-
-
33745764824
-
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer
-
Mukherjee S., Frolova N., Sadlonova A., Novak Z., Steg A., Page G.P., Welch D.R., Lobo-Ruppert S.M., Ruppert J.M., Johnson M.R., Frost A.R. Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer. Cancer Biol. Ther. 2006, 5:674-683.
-
(2006)
Cancer Biol. Ther.
, vol.5
, pp. 674-683
-
-
Mukherjee, S.1
Frolova, N.2
Sadlonova, A.3
Novak, Z.4
Steg, A.5
Page, G.P.6
Welch, D.R.7
Lobo-Ruppert, S.M.8
Ruppert, J.M.9
Johnson, M.R.10
Frost, A.R.11
-
49
-
-
79957895813
-
Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer
-
O'Toole S.A., Machalek D.A., Shearer R.F., Millar E.K., Nair R., Schofield P., McLeod D., Cooper C.L., McNeil C.M., McFarland A., Nguyen A., Ormandy C.J., Qiu M.R., Rabinovich B., Martelotto L.G., Vu D., Hannigan G.E., Musgrove E.A., Christ D., Sutherland R.L., Watkins D.N., Swarbrick A. Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer. Cancer Res. 2011, 71:4002-4014.
-
(2011)
Cancer Res.
, vol.71
, pp. 4002-4014
-
-
O'Toole, S.A.1
Machalek, D.A.2
Shearer, R.F.3
Millar, E.K.4
Nair, R.5
Schofield, P.6
McLeod, D.7
Cooper, C.L.8
McNeil, C.M.9
McFarland, A.10
Nguyen, A.11
Ormandy, C.J.12
Qiu, M.R.13
Rabinovich, B.14
Martelotto, L.G.15
Vu, D.16
Hannigan, G.E.17
Musgrove, E.A.18
Christ, D.19
Sutherland, R.L.20
Watkins, D.N.21
Swarbrick, A.22
more..
-
50
-
-
34250891981
-
The primary cilium: keeper of the key to cell division
-
Pan J., Snell W. The primary cilium: keeper of the key to cell division. Cell 2007, 129:1255-1257.
-
(2007)
Cell
, vol.129
, pp. 1255-1257
-
-
Pan, J.1
Snell, W.2
-
51
-
-
33646270662
-
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
-
Pan Y., Bai C.B., Joyner A.L., Wang B. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol. Cell Biol. 2006, 26:3365-3377.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 3365-3377
-
-
Pan, Y.1
Bai, C.B.2
Joyner, A.L.3
Wang, B.4
-
52
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29(9):e45.
-
(2001)
Nucleic Acids Res.
, vol.29
, Issue.9
-
-
Pfaffl, M.W.1
-
53
-
-
0033136040
-
Prostate development requires Sonic Hedgehog expressed by the urogenital sinus epithelium
-
Podlasek C.A., Barnett D.H., Clemens J.Q., Bak P.M., Bushman W. Prostate development requires Sonic Hedgehog expressed by the urogenital sinus epithelium. Dev. Biol. 1999, 209:28-39.
-
(1999)
Dev. Biol.
, vol.209
, pp. 28-39
-
-
Podlasek, C.A.1
Barnett, D.H.2
Clemens, J.Q.3
Bak, P.M.4
Bushman, W.5
-
54
-
-
67650889517
-
Mammary tumor phenotypes in wild-type aging female FVB/N mice with pituitary prolactinomas
-
Radaelli E., Arnold A., Papanikolaou A., Garcia-Fernandez R.A., Mattiello S., Scanziani E., Cardiff R.D. Mammary tumor phenotypes in wild-type aging female FVB/N mice with pituitary prolactinomas. Vet. Pathol. 2009, 46:736-745.
-
(2009)
Vet. Pathol.
, vol.46
, pp. 736-745
-
-
Radaelli, E.1
Arnold, A.2
Papanikolaou, A.3
Garcia-Fernandez, R.A.4
Mattiello, S.5
Scanziani, E.6
Cardiff, R.D.7
-
55
-
-
0029006446
-
Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation
-
Robinson G.W., McKnight R.A., Smith G.H., Hennighausen L. Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation. Development 1995, 121:2079-2090.
-
(1995)
Development
, vol.121
, pp. 2079-2090
-
-
Robinson, G.W.1
McKnight, R.A.2
Smith, G.H.3
Hennighausen, L.4
-
56
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M., Vaillant F., Simpson K.J., Stingl J., Smyth G.K., Asselin-Labat M.L., Wu L., Lindeman G.J., Visvader J.E. Generation of a functional mammary gland from a single stem cell. Nature 2006, 439:84-88.
-
(2006)
Nature
, vol.439
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
Stingl, J.4
Smyth, G.K.5
Asselin-Labat, M.L.6
Wu, L.7
Lindeman, G.J.8
Visvader, J.E.9
-
57
-
-
72449149112
-
The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts
-
Shaw A., Gipp J., Bushman W. The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts. Oncogene 2009, 28:4480-4490.
-
(2009)
Oncogene
, vol.28
, pp. 4480-4490
-
-
Shaw, A.1
Gipp, J.2
Bushman, W.3
-
58
-
-
79953746223
-
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
-
Shin K., Lee J., Guo N., Kim J., Lim A., Qu L., Mysorekar I.U., Beachy P.A. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 2011, 472:110-114.
-
(2011)
Nature
, vol.472
, pp. 110-114
-
-
Shin, K.1
Lee, J.2
Guo, N.3
Kim, J.4
Lim, A.5
Qu, L.6
Mysorekar, I.U.7
Beachy, P.A.8
-
59
-
-
33645823699
-
Hedgehog signaling maintains resident hepatic progenitors throughout life
-
Sicklick J.K., Li Y.X., Melhem A., Schmelzer E., Zdanowicz M., Huang J., Caballero M., Fair J.H., Ludlow J.W., McClelland R.E., Reid L.M., Diehl A.M. Hedgehog signaling maintains resident hepatic progenitors throughout life. Am J Physiol Gastrointest Liver Physiol. 2006, 290:G859-G870.
-
(2006)
Am J Physiol Gastrointest Liver Physiol.
, vol.290
-
-
Sicklick, J.K.1
Li, Y.X.2
Melhem, A.3
Schmelzer, E.4
Zdanowicz, M.5
Huang, J.6
Caballero, M.7
Fair, J.H.8
Ludlow, J.W.9
McClelland, R.E.10
Reid, L.M.11
Diehl, A.M.12
-
60
-
-
0025415270
-
Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium
-
Smith G.H., Mehrel T., Roop D.R. Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ. 1990, 1:161-170.
-
(1990)
Cell Growth Differ.
, vol.1
, pp. 161-170
-
-
Smith, G.H.1
Mehrel, T.2
Roop, D.R.3
-
61
-
-
30144432901
-
Purification and unique properties of mammary epithelial stem cells
-
Stingl J., Eirew P., Ricketson I., Shackleton M., Vaillant F., Choi D., Li H.I., Eaves C.J. Purification and unique properties of mammary epithelial stem cells. Nature 2006, 439:993-997.
-
(2006)
Nature
, vol.439
, pp. 993-997
-
-
Stingl, J.1
Eirew, P.2
Ricketson, I.3
Shackleton, M.4
Vaillant, F.5
Choi, D.6
Li, H.I.7
Eaves, C.J.8
-
62
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer S.P., di Magliano M.P., Heiser P.W., Nielsen C.M., Roberts D.J., Lauwers G.Y., Qi Y.P., Gysin S., Fernandez-del Castillo C., Yajnik V., Antoniu B., McMahon M., Warshaw A.L., Hebrok M. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003, 425:851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
63
-
-
68049128117
-
Paracrine Hedgehog signaling in cancer
-
Theunissen J.W., de Sauvage F.J. Paracrine Hedgehog signaling in cancer. Cancer Res. 2009, 69:6007-6010.
-
(2009)
Cancer Res.
, vol.69
, pp. 6007-6010
-
-
Theunissen, J.W.1
de Sauvage, F.J.2
-
64
-
-
0032894188
-
Racial differences in the presentation and surgical management of breast cancer
-
Velanovich V., Yood M.U., Bawle U., Nathanson S.D., Strand V.F., Talpos G.B., Szymanski W., Lewis F.R. Racial differences in the presentation and surgical management of breast cancer. Surgery 1999, 125:375-379.
-
(1999)
Surgery
, vol.125
, pp. 375-379
-
-
Velanovich, V.1
Yood, M.U.2
Bawle, U.3
Nathanson, S.D.4
Strand, V.F.5
Talpos, G.B.6
Szymanski, W.7
Lewis, F.R.8
-
65
-
-
79952193499
-
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened
-
Visbal A.P., LaMarca H.L., Villanueva H., Toneff M.J., Li Y., Rosen J.M., Lewis M.T. Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev. Biol. 2011, 352:116-127.
-
(2011)
Dev. Biol.
, vol.352
, pp. 116-127
-
-
Visbal, A.P.1
LaMarca, H.L.2
Villanueva, H.3
Toneff, M.J.4
Li, Y.5
Rosen, J.M.6
Lewis, M.T.7
-
66
-
-
0036339643
-
An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal
-
Wagner K.U., Boulanger C.A., Henry M.D., Sgagias M., Hennighausen L., Smith G.H. An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal. Development 2002, 129:1377-1386.
-
(2002)
Development
, vol.129
, pp. 1377-1386
-
-
Wagner, K.U.1
Boulanger, C.A.2
Henry, M.D.3
Sgagias, M.4
Hennighausen, L.5
Smith, G.H.6
-
67
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang B., Fallon J.F., Beachy P.A. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 2000, 100:423-434.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
68
-
-
0022589974
-
Control of type IV collagen production in rat mammary epithelial and myoepithelial-like cells
-
Warburton M.J., Kimbell R., Rudland P.S., Ferns S.A., Barraclough R. Control of type IV collagen production in rat mammary epithelial and myoepithelial-like cells. J. Cell Physiol. 1986, 128:76-84.
-
(1986)
J. Cell Physiol.
, vol.128
, pp. 76-84
-
-
Warburton, M.J.1
Kimbell, R.2
Rudland, P.S.3
Ferns, S.A.4
Barraclough, R.5
-
69
-
-
0242669237
-
Hedgehog signaling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins D.N., Berman D.M., Burkholder S.G., Wang B., Beachy P.A., Baylin S.B. Hedgehog signaling within airway epithelial progenitors and in small-cell lung cancer. Nature 2003, 422:313-317.
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
70
-
-
52149119128
-
A paracrine requirement for hedgehog signaling in cancer
-
Yauch R.L., Gould S.E., Scales S.J., Tang T., Tian H., Ahn C.P., Marshall D., Fu L., Januario T., Kallop D., Nannini-Pepe M., Kotkow K., Marsters J.C., Rubin L.L., de Sauvage F.J. A paracrine requirement for hedgehog signaling in cancer. Nature 2008, 455:406-410.
-
(2008)
Nature
, vol.455
, pp. 406-410
-
-
Yauch, R.L.1
Gould, S.E.2
Scales, S.J.3
Tang, T.4
Tian, H.5
Ahn, C.P.6
Marshall, D.7
Fu, L.8
Januario, T.9
Kallop, D.10
Nannini-Pepe, M.11
Kotkow, K.12
Marsters, J.C.13
Rubin, L.L.14
de Sauvage, F.J.15
-
71
-
-
65549083026
-
Sonic hedgehog-responsive genes in the fetal prostate
-
Yu M., Gipp J., Yoon J.W., Iannaccone P., Walterhouse D., Bushman W. Sonic hedgehog-responsive genes in the fetal prostate. J. Biol. Chem. 2009, 284:5620-5629.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5620-5629
-
-
Yu, M.1
Gipp, J.2
Yoon, J.W.3
Iannaccone, P.4
Walterhouse, D.5
Bushman, W.6
-
72
-
-
70350784105
-
Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells. BMC
-
Zhang J., Lipinski R.J., Gipp J.J., Shaw A.K., Bushman W. Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells. BMC. Dev. Biol. 2009, 9:50.
-
(2009)
Dev. Biol.
, vol.9
, pp. 50
-
-
Zhang, J.1
Lipinski, R.J.2
Gipp, J.J.3
Shaw, A.K.4
Bushman, W.5
|