Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells

Stem Cells

Volumn 26, Issue 5, 2008, Pages 1253-1264

  Li, Na ^a   Singh, Samer ^a   Cherukuri, Pratima ^a   Li, Hua ^a   Yuan, Ziqiang ^a   Ellisen, Leif W ^b   Wang, Baolin ^c   Robbins, David ^a   DiRenzo, James ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Gli3; Hedgehog; Mammary progenitors; Mammary stem cells; Quiescence; TP63

Indexed keywords

PROTEIN P63; SHORT HAIRPIN RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI3; GLI3 PROTEIN, MOUSE; IHH PROTEIN, MOUSE; ISOPROTEIN; KRUPPEL LIKE FACTOR; NERVE PROTEIN; PHOSPHOPROTEIN; TRANSACTIVATOR PROTEIN; TRP63 PROTEIN, MOUSE;

ARTICLE; BREAST CELL; CELL PROLIFERATION; CONTROLLED STUDY; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MITOGENESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STEM CELL; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CYTOLOGY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PREGNANCY; PROMOTER REGION; PROTEIN BINDING; UDDER;

ERINACEIDAE;

ANIMALS; CELL LINE; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MAMMARY GLANDS, ANIMAL; MICE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; PHOSPHOPROTEINS; PREGNANCY; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN ISOFORMS; SIGNAL TRANSDUCTION; STEM CELLS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 47949105620     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0691     Document Type: Article

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