Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

Development

Volumn 136, Issue 9, 2009, Pages 1423-1432

  Moraes, Ricardo C ^a   Chang, Hong ^b   Harrington, Nikesha ^a   Landua, John D ^a   Prigge, Jonathan T ^a   Lane, Timothy F ^c   Wainwright, Brandon J ^d   Hamel, Paul A ^b   Lewis, Michael T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Ductal morphogenesis; Hedgehog; Hyperplasia; Mouse; Pituitary isograft; SMO; Tissue interaction

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; CELL SURFACE RECEPTOR; ESTROGEN; PATCHED RECEPTORS; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST DUCT; BREAST EPITHELIUM; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE DISRUPTION; GENE FREQUENCY; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; ISOGRAFT; MALE; MAMMARY GLAND; MORPHOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STROMA; ANIMAL; CONGENITAL MALFORMATION; DRUG EFFECT; EPITHELIUM; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HETEROZYGOTE; HOMOZYGOTE; HUMAN; METABOLISM; MOUSE MAMMARY TUMOR ONCOVIRUS; MUTATION; NUCLEOTIDE SEQUENCE; REPORTER GENE; STROMA CELL; TRANSGENIC MOUSE; UDDER;

ANIMALIA; ERINACEIDAE; MOUSE MAMMARY TUMOR VIRUS; MUS;

ANIMALS; BASE SEQUENCE; EPITHELIUM; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; MAMMARY GLANDS, ANIMAL; MAMMARY TUMOR VIRUS, MOUSE; MICE; MICE, TRANSGENIC; MORPHOGENESIS; MUTATION; POLYMORPHISM, GENETIC; PROGESTERONE; RECEPTORS, CELL SURFACE; STROMAL CELLS;

EID: 67649225569     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.023994     Document Type: Article

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