메뉴 건너뛰기




Volumn 69, Issue 21, 2012, Pages 3601-3612

The Akt-associated microRNAs

Author keywords

Akt; Akt microRNA regulatory network; microRNAs; miR 101; miR 145

Indexed keywords

MASPIN; MICRORNA; MICRORNA 101; MICRORNA 145; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; TRANSCRIPTION FACTOR FOXO;

EID: 84867813282     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1129-8     Document Type: Review
Times cited : (59)

References (126)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V (2004) The functions of animal microRNAs. Nature 431(7006):350-355
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 3
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman RC, Farh KK, Burge CB, Bartel DP (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19(1):92-105
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 4
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and microRNAs
    • Hobert O (2008) Gene regulation by transcription factors and microRNAs. Science 319(5871):1785-1786
    • (2008) Science , vol.319 , Issue.5871 , pp. 1785-1786
    • Hobert, O.1
  • 5
    • 34848922072 scopus 로고    scopus 로고
    • MiRNAs play a tune
    • Hobert O (2007) miRNAs play a tune. Cell 131(1):22-24
    • (2007) Cell , vol.131 , Issue.1 , pp. 22-24
    • Hobert, O.1
  • 6
    • 27244432205 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Chen CZ (2005) MicroRNAs as oncogenes and tumor suppressors. N Engl J Med 353(17):1768-1771
    • (2005) N Engl J Med , vol.353 , Issue.17 , pp. 1768-1771
    • Chen, C.Z.1
  • 7
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, Kim M, Han J et al (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23(20):4051-4060
    • (2004) EMBO J , vol.23 , Issue.20 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3
  • 8
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT et al (2005) A microRNA polycistron as a potential human oncogene. Nature 435(7043): 828-833
    • (2005) Nature , vol.435 , Issue.7043 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 10
    • 33646258751 scopus 로고    scopus 로고
    • Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer
    • Xi Y, Shalgi R, Fodstad O, Pilpel Y, Ju J (2006) Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer. Clin Cancer Res 12(7 Pt 1):2014-2024
    • (2006) Clin Cancer Res , vol.12 PART 1 , Issue.7 , pp. 2014-2024
    • Xi, Y.1    Shalgi, R.2    Fodstad, O.3    Pilpel, Y.4    Ju, J.5
  • 11
    • 37049010980 scopus 로고    scopus 로고
    • The guardian's little helper: MicroRNAs in the p53 tumor suppressor network
    • He X, He L, Hannon GJ (2007) The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res 67(23):11099-11101
    • (2007) Cancer Res , vol.67 , Issue.23 , pp. 11099-11101
    • He, X.1    He, L.2    Hannon, G.J.3
  • 12
    • 62549148270 scopus 로고    scopus 로고
    • P53 represses c-Myc through induction of the tumor suppressor miR-145
    • Sachdeva M, Zhu S, Wu F et al (2009) p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Nat Acad Sci USA 106(9):3207-3212
    • (2009) Proc Nat Acad Sci USA , vol.106 , Issue.9 , pp. 3207-3212
    • Sachdeva, M.1    Zhu, S.2    Wu, F.3
  • 13
    • 43449100341 scopus 로고    scopus 로고
    • REST maintains self-renewal and pluripotency of embryonic stem cells
    • Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S (2008) REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 453(7192):223-227
    • (2008) Nature , vol.453 , Issue.7192 , pp. 223-227
    • Singh, S.K.1    Kagalwala, M.N.2    Parker-Thornburg, J.3    Adams, H.4    Majumder, S.5
  • 14
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Saito Y, Liang G, Egger G et al (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9(6):435-443
    • (2006) Cancer Cell , vol.9 , Issue.6 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3
  • 15
    • 32944462300 scopus 로고    scopus 로고
    • Rapid alteration of microRNA levels by histone deacetylase inhibition
    • Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC (2006) Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 66(3):1277-1281
    • (2006) Cancer Res , vol.66 , Issue.3 , pp. 1277-1281
    • Scott, G.K.1    Mattie, M.D.2    Berger, C.E.3    Benz, S.C.4    Benz, C.C.5
  • 16
    • 47949100595 scopus 로고    scopus 로고
    • Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
    • Newman MA, Thomson JM, Hammond SM (2008) Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 14(8):1539-1549
    • (2008) RNA , vol.14 , Issue.8 , pp. 1539-1549
    • Newman, M.A.1    Thomson, J.M.2    Hammond, S.M.3
  • 17
    • 52049124806 scopus 로고    scopus 로고
    • Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
    • Piskounova E, Viswanathan SR, Janas M et al (2008) Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 283(31): 21310-21314
    • (2008) J Biol Chem , vol.283 , Issue.31 , pp. 21310-21314
    • Piskounova, E.1    Viswanathan, S.R.2    Janas, M.3
  • 18
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak A, Fuchs H, Smirnova L et al (2008) A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 10(8):987-993
    • (2008) Nat Cell Biol , vol.10 , Issue.8 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3
  • 19
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI (2008) Selective blockade of microRNA processing by Lin28. Science 320(5872): 97-100
    • (2008) Science , vol.320 , Issue.5872 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 21
    • 39749143354 scopus 로고    scopus 로고
    • Targeted deletion reveals essential and overlapping functions of the miR- 17 through 92 family of miRNA clusters
    • Ventura A, Young AG, Winslow MM et al (2008) Targeted deletion reveals essential and overlapping functions of the miR- 17 through 92 family of miRNA clusters. Cell 132(5):875-886
    • (2008) Cell , vol.132 , Issue.5 , pp. 875-886
    • Ventura, A.1    Young, A.G.2    Winslow, M.M.3
  • 22
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen CZ, Li L, Lodish HF, Bartel DP (2004) MicroRNAs modulate hematopoietic lineage differentiation. Science 303(5654): 83-86
    • (2004) Science , vol.303 , Issue.5654 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 23
    • 6044244941 scopus 로고    scopus 로고
    • Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
    • Kasashima K, Nakamura Y, Kozu T (2004) Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. Biochem Biophys Res Commun 322(2):403-410
    • (2004) Biochem Biophys Res Commun , vol.322 , Issue.2 , pp. 403-410
    • Kasashima, K.1    Nakamura, Y.2    Kozu, T.3
  • 24
    • 10344243662 scopus 로고    scopus 로고
    • MicroRNA-143 regulates adipocyte differentiation
    • Esau C, Kang X, Peralta E et al (2004) MicroRNA-143 regulates adipocyte differentiation. J Biol Chem 279(50):52361-52365
    • (2004) J Biol Chem , vol.279 , Issue.50 , pp. 52361-52365
    • Esau, C.1    Kang, X.2    Peralta, E.3
  • 25
    • 33748432997 scopus 로고    scopus 로고
    • MicroRNAs in muscle differentiation: Lessons from Drosophila and beyond
    • Nguyen HT, Frasch M (2006) MicroRNAs in muscle differentiation: lessons from Drosophila and beyond. Curr Opin Genet Dev 16(5):533-539
    • (2006) Curr Opin Genet Dev , vol.16 , Issue.5 , pp. 533-539
    • Nguyen, H.T.1    Frasch, M.2
  • 26
    • 33745109920 scopus 로고    scopus 로고
    • Molecular processes during fat cell development revealed by gene expression profiling and functional annotation
    • Hackl H, Burkard TR, Sturn A et al (2005) Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol 6(13):R108
    • (2005) Genome Biol , vol.6 , Issue.13
    • Hackl, H.1    Burkard, T.R.2    Sturn, A.3
  • 27
    • 33846135109 scopus 로고    scopus 로고
    • MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
    • Boutz PL, Chawla G, Stoilov P, Black DL (2007) MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev 21(1):71-84
    • (2007) Genes Dev , vol.21 , Issue.1 , pp. 71-84
    • Boutz, P.L.1    Chawla, G.2    Stoilov, P.3    Black, D.L.4
  • 28
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • Rinn JL, Kertesz M, Wang JK et al (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129(7):1311-1323
    • (2007) Cell , vol.129 , Issue.7 , pp. 1311-1323
    • Rinn, J.L.1    Kertesz, M.2    Wang, J.K.3
  • 29
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang TC, Wentzel EA, Kent OA et al (2007) Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 26(5):745-752
    • (2007) Mol Cell , vol.26 , Issue.5 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3
  • 30
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
    • Raver-Shapira N, Marciano E, Meiri E et al (2007) Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 26(5):731-743
    • (2007) Mol Cell , vol.26 , Issue.5 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3
  • 31
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65(14):6029-6033
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 32
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • Meng F, Henson R, Lang M et al (2006) Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 130(7):2113- 2129
    • (2006) Gastroenterology , vol.130 , Issue.7 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3
  • 33
    • 33749236251 scopus 로고    scopus 로고
    • MicroRNA: A new player in stem cells
    • Zhang B, Pan X, Anderson TA (2006) MicroRNA: a new player in stem cells. J Cell Physiol 209(2):266-269
    • (2006) J Cell Physiol , vol.209 , Issue.2 , pp. 266-269
    • Zhang, B.1    Pan, X.2    Anderson, T.A.3
  • 34
    • 20544458318 scopus 로고    scopus 로고
    • Stem cell division is regulated by the microRNA pathway
    • Hatfield SD, Shcherbata HR, Fischer KA et al (2005) Stem cell division is regulated by the microRNA pathway. Nature 435(7044):974-978
    • (2005) Nature , vol.435 , Issue.7044 , pp. 974-978
    • Hatfield, S.D.1    Shcherbata, H.R.2    Fischer, K.A.3
  • 35
    • 0042442335 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs
    • Houbaviy HB, Murray MF, Sharp PA (2003) Embryonic stem cell-specific microRNAs. Dev Cell 5(2):351-358
    • (2003) Dev Cell , vol.5 , Issue.2 , pp. 351-358
    • Houbaviy, H.B.1    Murray, M.F.2    Sharp, P.A.3
  • 36
    • 2942534403 scopus 로고    scopus 로고
    • Human embryonic stem cells express a unique set of microRNAs
    • Suh MR, Lee Y, Kim JY et al (2004) Human embryonic stem cells express a unique set of microRNAs. Dev Biol 270(2): 488-498
    • (2004) Dev Biol , vol.270 , Issue.2 , pp. 488-498
    • Suh, M.R.1    Lee, Y.2    Kim, J.Y.3
  • 37
    • 0037320941 scopus 로고    scopus 로고
    • Numerous microRNPs in neuronal cells containing novel microRNAs
    • Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G (2003) Numerous microRNPs in neuronal cells containing novel microRNAs. RNA 9(2):180-186
    • (2003) RNA , vol.9 , Issue.2 , pp. 180-186
    • Dostie, J.1    Mourelatos, Z.2    Yang, M.3    Sharma, A.4    Dreyfuss, G.5
  • 38
    • 33645321647 scopus 로고    scopus 로고
    • MicroRNAs in cell proliferation, cell death, and tumorigenesis
    • Hwang HW, Mendell JT (2006) MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94(6):776-780
    • (2006) Br J Cancer , vol.94 , Issue.6 , pp. 776-780
    • Hwang, H.W.1    Mendell, J.T.2
  • 39
    • 22144461002 scopus 로고    scopus 로고
    • MiRNAs, cancer, and stem cell division
    • Croce CM, Calin GA (2005) miRNAs, cancer, and stem cell division. Cell 122(1):6-7
    • (2005) Cell , vol.122 , Issue.1 , pp. 6-7
    • Croce, C.M.1    Calin, G.A.2
  • 40
    • 30644475098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes
    • Hammond SM (2006) MicroRNAs as oncogenes. Curr Opin Genet Dev 16(1):4-9
    • (2006) Curr Opin Genet Dev , vol.16 , Issue.1 , pp. 4-9
    • Hammond, S.M.1
  • 41
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6(4):259-269
    • (2006) Nat Rev Cancer , vol.6 , Issue.4 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 42
    • 18144365478 scopus 로고    scopus 로고
    • MicroRNA biogenesis and cancer
    • Gregory RI, Shiekhattar R (2005) MicroRNA biogenesis and cancer. Cancer Res 65(9):3509-3512
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3509-3512
    • Gregory, R.I.1    Shiekhattar, R.2
  • 43
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin GA, Liu CG, Sevignani C et al (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 101(32):11755-11760
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.32 , pp. 11755-11760
    • Calin, G.A.1    Liu, C.G.2    Sevignani, C.3
  • 44
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M et al (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99(24):15524-15529
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.24 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 45
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson SM, Grosshans H, Shingara J et al (2005) RAS is regulated by the let-7 microRNA family. Cell 120(5):635-647
    • (2005) Cell , vol.120 , Issue.5 , pp. 635-647
    • Johnson, S.M.1    Grosshans, H.2    Shingara, J.3
  • 46
    • 25444520537 scopus 로고    scopus 로고
    • MiR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M et al (2005) miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102(39):13944-13949
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.39 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 47
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y et al (2005) A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 65(21): 9628-9632
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 48
    • 33646056975 scopus 로고    scopus 로고
    • A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors
    • Voorhoeve PM, le Sage C, Schrier M et al (2006) A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124(6):1169-1181
    • (2006) Cell , vol.124 , Issue.6 , pp. 1169-1181
    • Voorhoeve, P.M.1    Le Sage, C.2    Schrier, M.3
  • 49
    • 34247495591 scopus 로고    scopus 로고
    • MiR-21-mediated tumor growth
    • Si ML, Zhu S, Wu H et al (2007) miR-21-mediated tumor growth. Oncogene 26(19):2799-2803
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2799-2803
    • Si, M.L.1    Zhu, S.2    Wu, H.3
  • 50
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1
    • Zhu S, Si ML, Wu H, Mo YY (2007) MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282(19):14328-14336
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 51
    • 40249092910 scopus 로고    scopus 로고
    • MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
    • Zhu S, Wu H, Wu F et al (2008) MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18(3):350-359
    • (2008) Cell Res , vol.18 , Issue.3 , pp. 350-359
    • Zhu, S.1    Wu, H.2    Wu, F.3
  • 52
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J, Weinberg RA (2007) Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449(7163):682-688
    • (2007) Nature , vol.449 , Issue.7163 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 53
    • 38049115129 scopus 로고    scopus 로고
    • Endogenous human microRNAs that suppress breast cancer metastasis
    • Tavazoie SF, Alarco'n C, Oskarsson T et al (2008) Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451(7175):147-152
    • (2008) Nature , vol.451 , Issue.7175 , pp. 147-152
    • Tavazoie, S.F.1    Alarco'N, C.2    Oskarsson, T.3
  • 54
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA et al (2005) MicroRNA expression profiles classify human cancers. Nature 435(7043):834-838
    • (2005) Nature , vol.435 , Issue.7043 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 55
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A et al (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353(17):1793-1801
    • (2005) N Engl J Med , vol.353 , Issue.17 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 56
    • 33644819964 scopus 로고    scopus 로고
    • Unique microRNA molecular profiles in lung cancer diagnosis and prognosis
    • Yanaihara N, Caplen N, Bowman E et al (2006) Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9(3):189-198
    • (2006) Cancer Cell , vol.9 , Issue.3 , pp. 189-198
    • Yanaihara, N.1    Caplen, N.2    Bowman, E.3
  • 57
    • 33845608588 scopus 로고    scopus 로고
    • Identification of differentially expressed microRNAs by microarray: A possible role for microRNA genes in pituitary adenomas
    • Bottoni A, Zatelli MC, Ferracin M et al (2007) Identification of differentially expressed microRNAs by microarray: a possible role for microRNA genes in pituitary adenomas. J Cell Physiol 210(2):370-377
    • (2007) J Cell Physiol , vol.210 , Issue.2 , pp. 370-377
    • Bottoni, A.1    Zatelli, M.C.2    Ferracin, M.3
  • 58
    • 33947104498 scopus 로고    scopus 로고
    • A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas
    • Wang T, Zhang X, Obijuru L et al (2007) A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer 46(4):336-347
    • (2007) Genes Chromosomes Cancer , vol.46 , Issue.4 , pp. 336-347
    • Wang, T.1    Zhang, X.2    Obijuru, L.3
  • 59
    • 34247648712 scopus 로고    scopus 로고
    • MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis
    • Debernardi S, Skoulakis S, Molloy G et al (2007) MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. Leukemia 21(5):912-916
    • (2007) Leukemia , vol.21 , Issue.5 , pp. 912-916
    • Debernardi, S.1    Skoulakis, S.2    Molloy, G.3
  • 60
    • 33846813656 scopus 로고    scopus 로고
    • Expression profiling identifies microRNA signature in pancreatic cancer
    • Lee EJ, Gusev Y, Jiang J et al (2007) Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 120(5):1046-1054
    • (2007) Int J Cancer , vol.120 , Issue.5 , pp. 1046-1054
    • Lee, E.J.1    Gusev, Y.2    Jiang, J.3
  • 61
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG et al (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103(7):2257-2261
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.7 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 62
    • 68249093818 scopus 로고    scopus 로고
    • Targeting the phosphoinositide 3-kinase pathway in cancer
    • Liu P, Cheng H, Roberts TM, Zhao JJ (2009) Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov 8(8):627-644
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.8 , pp. 627-644
    • Liu, P.1    Cheng, H.2    Roberts, T.M.3    Zhao, J.J.4
  • 63
    • 67749122122 scopus 로고    scopus 로고
    • Targeting PI3K signaling in cancer: Opportunities, challenges and limitations
    • Engelman JA (2009) Targeting PI3K signaling in cancer: opportunities, challenges and limitations. Nat Rev Cancer 9(8):550-562
    • (2009) Nat Rev Cancer , vol.9 , Issue.8 , pp. 550-562
    • Engelman, J.A.1
  • 64
    • 22744449073 scopus 로고    scopus 로고
    • An Akt/betaarrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
    • Beaulieu JM, Sotnikova TD, Marion S et al (2005) An Akt/betaarrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122(2):261-273
    • (2005) Cell , vol.122 , Issue.2 , pp. 261-273
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Marion, S.3
  • 65
    • 0035850916 scopus 로고    scopus 로고
    • Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
    • Maira SM, Galetic I, Brazil DP et al (2001) Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. Science 294(5541):374-380
    • (2001) Science , vol.294 , Issue.5541 , pp. 374-380
    • Maira, S.M.1    Galetic, I.2    Brazil, D.P.3
  • 66
    • 34548289502 scopus 로고    scopus 로고
    • Dynamic FoxO transcription factors
    • Huang H, Tindall DJ (2007) Dynamic FoxO transcription factors. J Cell Sci 120(Pt 15):2479-2487
    • (2007) J Cell Sci , vol.120 , Issue.PART 15 , pp. 2479-2487
    • Huang, H.1    Tindall, D.J.2
  • 67
    • 0035949588 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/ Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
    • Mayo LD, Donner DB (2001) A phosphatidylinositol 3-kinase/ Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci USA 98(20): 11598-11603
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.20 , pp. 11598-11603
    • Mayo, L.D.1    Donner, D.B.2
  • 68
    • 0035736487 scopus 로고    scopus 로고
    • HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
    • Zhou BP, Liao Y, Xia W et al (2001) HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat Cell Biol 3(11):973-982
    • (2001) Nat Cell Biol , vol.3 , Issue.11 , pp. 973-982
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3
  • 69
    • 60549112361 scopus 로고    scopus 로고
    • Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor
    • Segura MF, Hanniford D, Menendez S et al (2009) Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci USA 106(6):1814-1819
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.6 , pp. 1814-1819
    • Segura, M.F.1    Hanniford, D.2    Menendez, S.3
  • 70
    • 24644519490 scopus 로고    scopus 로고
    • The transcriptional landscape of the mammalian genome
    • Carninci P, Kasukawa T, Katayama S et al (2005) The transcriptional landscape of the mammalian genome. Science 309(5740):1559-1563
    • (2005) Science , vol.309 , Issue.5740 , pp. 1559-1563
    • Carninci, P.1    Kasukawa, T.2    Katayama, S.3
  • 71
    • 78650813084 scopus 로고    scopus 로고
    • Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a
    • Lin H, Dai T, Xiong H et al (2010) Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a. PLoS ONE 5(12):e15797
    • (2010) PLoS ONE , vol.5 , Issue.12
    • Lin, H.1    Dai, T.2    Xiong, H.3
  • 72
    • 77952760958 scopus 로고    scopus 로고
    • Foxo3a regulates apoptosis by negatively targeting miR-21
    • Wang K, Li PF (2010) Foxo3a regulates apoptosis by negatively targeting miR-21. J Biol Chem 285(22):16958-16966
    • (2010) J Biol Chem , vol.285 , Issue.22 , pp. 16958-16966
    • Wang, K.1    Li, P.F.2
  • 73
    • 78249255491 scopus 로고    scopus 로고
    • FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis
    • Gan B, Lim C, Chu G et al (2010) FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell 18(5):472-484
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 472-484
    • Gan, B.1    Lim, C.2    Chu, G.3
  • 74
    • 77957820678 scopus 로고    scopus 로고
    • Vitamin D3 upregulated protein 1 (VDUP1) is regulated by FOXO3A and miR- 17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts
    • de Zhuo X, Niu XH, Chen YC et al (2010) Vitamin D3 upregulated protein 1 (VDUP1) is regulated by FOXO3A and miR- 17-5p at the transcriptional and post-transcriptional levels, respectively, in senescent fibroblasts. J Biol Chem 285(41): 31491-31501
    • (2010) J Biol Chem , vol.285 , Issue.41 , pp. 31491-31501
    • De Zhuo, X.1    Niu, X.H.2    Chen, Y.C.3
  • 75
    • 0346455772 scopus 로고    scopus 로고
    • Posttranslational modification of MDM2
    • Meek DW, Knippschild U (2003) Posttranslational modification of MDM2. Mol Cancer Res 1(14):1017-1026
    • (2003) Mol Cancer Res , vol.1 , Issue.14 , pp. 1017-1026
    • Meek, D.W.1    Knippschild, U.2
  • 76
    • 67749143728 scopus 로고    scopus 로고
    • Modulation of microRNA processing by p53
    • Suzuki HI, Yamagata K, Sugimoto K et al (2009) Modulation of microRNA processing by p53. Nature 460(7254):529-533
    • (2009) Nature , vol.460 , Issue.7254 , pp. 529-533
    • Suzuki, H.I.1    Yamagata, K.2    Sugimoto, K.3
  • 77
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L, He X, Lim LP et al (2007) A microRNA component of the p53 tumour suppressor network. Nature 447(7148):1130-1134
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3
  • 78
    • 34547458550 scopus 로고    scopus 로고
    • P53-mediated activation of miRNA34 candidate tumor-suppressor genes
    • Bommer GT, Gerin I, Feng Y et al (2007) p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr Biol 17(15):1298-1307
    • (2007) Curr Biol , vol.17 , Issue.15 , pp. 1298-1307
    • Bommer, G.T.1    Gerin, I.2    Feng, Y.3
  • 79
    • 79551610902 scopus 로고    scopus 로고
    • MiR-605 joins p53 network to form a p53:miR-605:mdm2 positive feedback loop in response to stress
    • Xiao J, Lin H, Luo X, Wang Z (2011) miR-605 joins p53 network to form a p53:miR-605:mdm2 positive feedback loop in response to stress. EMBO J 30(24):5021
    • (2011) EMBO J , vol.30 , Issue.24 , pp. 5021
    • Xiao, J.1    Lin, H.2    Luo, X.3    Wang, Z.4
  • 80
    • 70349220767 scopus 로고    scopus 로고
    • Repression of the miR-17- 92 cluster by p53 has an important function in hypoxia-induced apoptosis
    • Yan HL, Xue G, Mei Q et al (2009) Repression of the miR-17- 92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J 28(18):2719-2732
    • (2009) EMBO J , vol.28 , Issue.18 , pp. 2719-2732
    • Yan, H.L.1    Xue, G.2    Mei, Q.3
  • 81
    • 80054115192 scopus 로고    scopus 로고
    • Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53
    • Saleh AD, Savage JE, Cao L et al (2011) Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53. PLoS ONE 6(10):e24429
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Saleh, A.D.1    Savage, J.E.2    Cao, L.3
  • 82
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu CG et al (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65(16):7065-7070
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.G.3
  • 83
    • 37548999684 scopus 로고    scopus 로고
    • Altered microRNA expression confined to specific epithelial cell subpopulations in breast cancer
    • Sempere LF, Christensen M, Silahtaroglu A et al (2007) Altered microRNA expression confined to specific epithelial cell subpopulations in breast cancer. Cancer Res 67(24):11612-11620
    • (2007) Cancer Res , vol.67 , Issue.24 , pp. 11612-11620
    • Sempere, L.F.1    Christensen, M.2    Silahtaroglu, A.3
  • 84
    • 33747628074 scopus 로고    scopus 로고
    • Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues
    • Bandres E, Cubedo E, Agirre X et al (2006) Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 5(1):29
    • (2006) Mol Cancer , vol.5 , Issue.1 , pp. 29
    • Bandres, E.1    Cubedo, E.2    Agirre, X.3
  • 85
    • 61449208911 scopus 로고    scopus 로고
    • Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke
    • Izzotti A, Calin GA, Arrigo P et al (2009) Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J 23(3):806-812
    • (2009) FASEB J , vol.23 , Issue.3 , pp. 806-812
    • Izzotti, A.1    Calin, G.A.2    Arrigo, P.3
  • 87
    • 36348994146 scopus 로고    scopus 로고
    • Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells
    • Shi B, Sepp-Lorenzino L, Prisco M et al (2007) Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem 282(45):32582-32590
    • (2007) J Biol Chem , vol.282 , Issue.45 , pp. 32582-32590
    • Shi, B.1    Sepp-Lorenzino, L.2    Prisco, M.3
  • 88
    • 35548995316 scopus 로고    scopus 로고
    • Downregulation of microRNAs-143 and -145 in B-cell malignancies
    • Akao Y, Nakagawa Y, Kitade Y, Kinoshita T, Naoe T (2007) Downregulation of microRNAs-143 and -145 in B-cell malignancies. Cancer Sci 98(12):1914-1920
    • (2007) Cancer Sci , vol.98 , Issue.12 , pp. 1914-1920
    • Akao, Y.1    Nakagawa, Y.2    Kitade, Y.3    Kinoshita, T.4    Naoe, T.5
  • 89
    • 67649448828 scopus 로고    scopus 로고
    • MiR-145 inhibits breast cancer cell growth through RTKN
    • Wang S, Bian C, Yang Z, et al (2009) miR-145 inhibits breast cancer cell growth through RTKN. Int J Oncol 34(5):1461-1466
    • (2009) Int J Oncol , vol.34 , Issue.5 , pp. 1461-1466
    • Wang, S.1    Bian, C.2    Yang, Z.3
  • 90
    • 74249123376 scopus 로고    scopus 로고
    • MiR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells
    • Spizzo R, Nicoloso MS, Lupini L et al (2009) miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells. Cell Death Differ 17(2):246-254
    • (2009) Cell Death Differ , vol.17 , Issue.2 , pp. 246-254
    • Spizzo, R.1    Nicoloso, M.S.2    Lupini, L.3
  • 91
    • 67650365554 scopus 로고    scopus 로고
    • Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation
    • Cho WC, Chow AS, Au JS (2009) Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer 45(12):2197-2206
    • (2009) Eur J Cancer , vol.45 , Issue.12 , pp. 2197-2206
    • Cho, W.C.1    Chow, A.S.2    Au, J.S.3
  • 92
    • 77949912309 scopus 로고    scopus 로고
    • MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer
    • Zhong M, Ma X, Sun C, Chen L (2010) MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer. Chem Biol Interact 184(3):431-438
    • (2010) Chem Biol Interact , vol.184 , Issue.3 , pp. 431-438
    • Zhong, M.1    Ma, X.2    Sun, C.3    Chen, L.4
  • 93
    • 77149124265 scopus 로고    scopus 로고
    • MiR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors
    • Ostenfeld MS, Bramsen JB, Lamy P et al (2009) miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene 29(7):1073-1084
    • (2009) Oncogene , vol.29 , Issue.7 , pp. 1073-1084
    • Ostenfeld, M.S.1    Bramsen, J.B.2    Lamy, P.3
  • 94
    • 77749320890 scopus 로고    scopus 로고
    • MicroRNA- 145 targets YES and STAT1 in colon cancer cells
    • Gregersen LH, Jacobsen AB, Frankel LB et al (2010) MicroRNA- 145 targets YES and STAT1 in colon cancer cells. PLoS ONE 5(1):e8836
    • (2010) PLoS ONE , vol.5 , Issue.1
    • Gregersen, L.H.1    Jacobsen, A.B.2    Frankel, L.B.3
  • 95
    • 84866248074 scopus 로고    scopus 로고
    • Glucocorticoid regulation of a novel HPV E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells
    • doi: 10.1002/path.3997
    • Shi M, Du L, Liu D et al (2012) Glucocorticoid regulation of a novel HPV E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. J Pathol. doi: 10.1002/path.3997
    • J Pathol , vol.2012
    • Shi, M.1    Du, L.2    Liu, D.3
  • 96
    • 84864307724 scopus 로고    scopus 로고
    • Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells
    • Sachdeva M, Liu Q, Cao J, Lu Z, Mo YY (2012) Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells. Nucleic Acids Res 40(14):6683-6692
    • (2012) Nucleic Acids Res , vol.40 , Issue.14 , pp. 6683-6692
    • Sachdeva, M.1    Liu, Q.2    Cao, J.3    Lu, Z.4    Mo, Y.Y.5
  • 97
    • 84871958603 scopus 로고    scopus 로고
    • Loss of microRNA-143/ 145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop
    • doi: 10.1038/onc.2012.28
    • Zhang J, Sun Q, Zhang Z et al (2012) Loss of microRNA-143/ 145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop. Oncogene. doi: 10.1038/onc.2012.28
    • (2012) Oncogene
    • Zhang, J.1    Sun, Q.2    Zhang, Z.3
  • 98
    • 78650204499 scopus 로고    scopus 로고
    • Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumorpromoting feed-forward pathway
    • Kent OA, Chivukula RR, Mullendore M et al (2010) Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumorpromoting feed-forward pathway. Genes Dev 24(24):2754-2759
    • (2010) Genes Dev , vol.24 , Issue.24 , pp. 2754-2759
    • Kent, O.A.1    Chivukula, R.R.2    Mullendore, M.3
  • 99
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H et al (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133(2):647-658
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3
  • 100
    • 79959918202 scopus 로고    scopus 로고
    • Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis
    • Ma X, Kumar M, Choudhury SN et al (2011) Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis. Proc Natl Acad Sci USA 108(25):10144-10149
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.25 , pp. 10144-10149
    • Ma, X.1    Kumar, M.2    Choudhury, S.N.3
  • 101
    • 70949104622 scopus 로고    scopus 로고
    • MiR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • Garofalo M, Di Leva G, Romano G et al (2009) miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 16(6):498-509
    • (2009) Cancer Cell , vol.16 , Issue.6 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3
  • 102
    • 77956292550 scopus 로고    scopus 로고
    • MiR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics
    • Bar N, Dikstein R (2010) miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kinetics. PLoS ONE 5(5):e10859
    • (2010) PLoS ONE , vol.5 , Issue.5
    • Bar, N.1    Dikstein, R.2
  • 103
    • 77749279797 scopus 로고    scopus 로고
    • Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486
    • Small EM, O'Rourke JR, Moresi V et al (2010) Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486. Proc Natl Acad Sci USA 107(9):4218-4223
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.9 , pp. 4218-4223
    • Small, E.M.1    O'Rourke, J.R.2    Moresi, V.3
  • 104
    • 77953948708 scopus 로고    scopus 로고
    • Identification of the miR-106b 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
    • Poliseno L, Salmena L, Riccardi L et al (2010) Identification of the miR-106b 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal 3(117):ra29
    • (2010) Sci Signal , vol.3 , Issue.117
    • Poliseno, L.1    Salmena, L.2    Riccardi, L.3
  • 105
    • 80053442041 scopus 로고    scopus 로고
    • MiR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis
    • Beezhold K, Liu J, Kan H et al (2011) miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis. Toxicol Sci 123(2):411-420
    • (2011) Toxicol Sci , vol.123 , Issue.2 , pp. 411-420
    • Beezhold, K.1    Liu, J.2    Kan, H.3
  • 106
    • 76049108572 scopus 로고    scopus 로고
    • MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling
    • Wong QW, Ching AK, Chan AW et al (2010) MiR-222 overexpression confers cell migratory advantages in hepatocellular carcinoma through enhancing AKT signaling. Clin Cancer Res 16(3):867-875
    • (2010) Clin Cancer Res , vol.16 , Issue.3 , pp. 867-875
    • Wong, Q.W.1    Ching, A.K.2    Chan, A.W.3
  • 107
    • 79955519053 scopus 로고    scopus 로고
    • Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway
    • Hamano R, Miyata H, Yamasaki M et al (2011) Overexpression of miR-200c induces chemoresistance in esophageal cancers mediated through activation of the Akt signaling pathway. Clin Cancer Res 17(9):3029-3038
    • (2011) Clin Cancer Res , vol.17 , Issue.9 , pp. 3029-3038
    • Hamano, R.1    Miyata, H.2    Yamasaki, M.3
  • 108
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • Varambally S, Cao Q, Mani RS et al (2008) Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322(5908):1695-1699
    • (2008) Science , vol.322 , Issue.5908 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3
  • 109
    • 65549083102 scopus 로고    scopus 로고
    • The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2
    • Friedman JM, Liang G, Liu CC et al (2009) The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2. Cancer Res 69(6):2623-2629
    • (2009) Cancer Res , vol.69 , Issue.6 , pp. 2623-2629
    • Friedman, J.M.1    Liang, G.2    Liu, C.C.3
  • 110
    • 59149098054 scopus 로고    scopus 로고
    • MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
    • Su H, Yang JR, Xu T et al (2009) MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 69(3):1135-1142
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 1135-1142
    • Su, H.1    Yang, J.R.2    Xu, T.3
  • 111
    • 79960469058 scopus 로고    scopus 로고
    • FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway
    • Kottakis F, Polytarchou C, Foltopoulou P et al (2011) FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101- EZH2 pathway.Mol Cell 43(2):285-298
    • (2011) Mol Cell , vol.43 , Issue.2 , pp. 285-298
    • Kottakis, F.1    Polytarchou, C.2    Foltopoulou, P.3
  • 112
    • 77958133262 scopus 로고    scopus 로고
    • Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation
    • Yan D, Ng WL, Zhang X et al (2010) Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation. PLoS ONE 5(7):e11397
    • (2010) PLoS ONE , vol.5 , Issue.7
    • Yan, D.1    Ng, W.L.2    Zhang, X.3
  • 113
    • 79951810419 scopus 로고    scopus 로고
    • MicroRNA-101-mediated Akt activation and estrogen-independent growth
    • Sachdeva M, Wu H, Ru P et al (2011) MicroRNA-101-mediated Akt activation and estrogen-independent growth. Oncogene 30(7):822-831
    • (2011) Oncogene , vol.30 , Issue.7 , pp. 822-831
    • Sachdeva, M.1    Wu, H.2    Ru, P.3
  • 114
    • 0015898197 scopus 로고
    • Estrogen receptor in a human cell line (MCF-7) from breast carcinoma
    • Brooks SC, Locke ER, Soule HD (1973) Estrogen receptor in a human cell line (MCF-7) from breast carcinoma. J Biol Chem 248(17):6251-6253
    • (1973) J Biol Chem , vol.248 , Issue.17 , pp. 6251-6253
    • Brooks, S.C.1    Locke, E.R.2    Soule, H.D.3
  • 115
    • 48549099077 scopus 로고    scopus 로고
    • MiR- 206 Expression is down-regulated in estrogen receptor alphapositive human breast cancer
    • KondoN, Toyama T, Sugiura H, FujiiY,YamashitaH(2008)miR- 206 Expression is down-regulated in estrogen receptor alphapositive human breast cancer. Cancer Res 68(13):5004-5008
    • (2008) Cancer Res , vol.68 , Issue.13 , pp. 5004-5008
    • Kondo, N.1    Toyama, T.2    Sugiura, H.3    Fujii, Y.4    Yamashita, H.5
  • 116
    • 34250843675 scopus 로고    scopus 로고
    • Themicro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines
    • AdamsBD, FurneauxH,WhiteBA(2007) Themicro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines. Mol Endocrinol 21(5):1132-1147
    • (2007) Mol Endocrinol , vol.21 , Issue.5 , pp. 1132-1147
    • Adams, B.D.1    Furneaux, H.2    White, B.A.3
  • 117
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA- 221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B et al (2008) MicroRNA- 221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 283(44):29897-29903
    • (2008) J Biol Chem , vol.283 , Issue.44 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3
  • 118
    • 57649174634 scopus 로고    scopus 로고
    • MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer
    • Zhao JJ, Lin J, Yang H et al (2008) MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer. J Biol Chem 283(45): 31079-31086
    • (2008) J Biol Chem , vol.283 , Issue.45 , pp. 31079-31086
    • Zhao, J.J.1    Lin, J.2    Yang, H.3
  • 119
    • 67650135755 scopus 로고    scopus 로고
    • MiR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA
    • Pandey DP, Picard D (2009) miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor alpha mRNA. Mol Cell Biol 29(13):3783-3790
    • (2009) Mol Cell Biol , vol.29 , Issue.13 , pp. 3783-3790
    • Pandey, D.P.1    Picard, D.2
  • 120
    • 0030113804 scopus 로고    scopus 로고
    • Cell signaling: MAGUK magic
    • Anderson JM (1996) Cell signaling: mAGUK magic. Curr Biol 6(4):382-384
    • (1996) Curr Biol , vol.6 , Issue.4 , pp. 382-384
    • Anderson, J.M.1
  • 121
    • 0034636038 scopus 로고    scopus 로고
    • Evidence for regulation of the PTEN tumor suppressor by a membranelocalized multi-PDZ domain containing scaffold protein MAGI- 2
    • Wu X, Hepner K, Castelino-Prabhu S et al (2000) Evidence for regulation of the PTEN tumor suppressor by a membranelocalized multi-PDZ domain containing scaffold protein MAGI- 2. Proc Natl Acad Sci USA 97(8):4233-4238
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.8 , pp. 4233-4238
    • Wu, X.1    Hepner, K.2    Castelino-Prabhu, S.3
  • 122
    • 66449118214 scopus 로고    scopus 로고
    • Switching Akt: From survival signaling to deadly response
    • Los M, Maddika S, Erb B, Schulze-Osthoff K (2009) Switching Akt: from survival signaling to deadly response. Bioessays 31(5):492-495
    • (2009) Bioessays , vol.31 , Issue.5 , pp. 492-495
    • Los, M.1    Maddika, S.2    Erb, B.3    Schulze-Osthoff, K.4
  • 123
    • 0027158460 scopus 로고
    • Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif
    • Ragimov N, Krauskopf A, Navot N et al (1993) Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene 8(5):1183-1193
    • (1993) Oncogene , vol.8 , Issue.5 , pp. 1183-1193
    • Ragimov, N.1    Krauskopf, A.2    Navot, N.3
  • 124
    • 23844476499 scopus 로고    scopus 로고
    • P53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest
    • Ho JS, Ma W, Mao DY, Benchimol S (2005) p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest. Mol Cell Biol 25(17):7423-7431
    • (2005) Mol Cell Biol , vol.25 , Issue.17 , pp. 7423-7431
    • Ho, J.S.1    Ma, W.2    Mao, D.Y.3    Benchimol, S.4
  • 125
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • Lowe SW, Sherr CJ (2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Curr Opin Genet Dev 13(1):77-83
    • (2003) Curr Opin Genet Dev , vol.13 , Issue.1 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 126
    • 65949102768 scopus 로고    scopus 로고
    • P53 and c-myc: How does the cell balance ''yin'' and ''yang''?
    • Sachdeva M, Mo YY (2009) p53 and c-myc: how does the cell balance ''yin'' and ''yang''? Cell Cycle 8(9):1303
    • (2009) Cell Cycle , vol.8 , Issue.9 , pp. 1303
    • Sachdeva, M.1    Mo, Y.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.