Role of P2X7 receptor-mediated IL-18/IL-18R signaling in morphine tolerance: Multiple glial-neuronal dialogues in the rat spinal cord

Journal of Pain

Volumn 13, Issue 10, 2012, Pages 945-958

  Chen, Meng Ling ^a   Cao, Hong ^a   Chu, Yu Xia ^a   Cheng, Long Zhen ^a   Liang, Ling Li ^a   Zhang, Yu Qiu ^a   Zhao, Zhi Qi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

glia neuronal interaction; IL 18; morphine tolerance; P2X7 receptor

Indexed keywords

BISINDOLYLMALEIMIDE; DEXTRO AMINO ACID; DEXTRO SERINE; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OXYGENASE; PROTEIN KINASE C GAMMA; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; SMALL INTERFERING RNA;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; DOWNSTREAM PROCESSING; ENZYME DEGRADATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MICROGLIA; MORPHINE TOLERANCE; NERVE CELL; NONHUMAN; PAIN; PAIN ASSESSMENT; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; RECORDING; SPINAL CORD DORSAL HORN; WHOLE CELL;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; DRUG TOLERANCE; INDOLES; INTERLEUKIN-18; MALE; MALEIMIDES; MORPHINE; NEUROGLIA; NEURONS; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-18; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84867004788     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.06.007     Document Type: Article

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