-
1
-
-
33644845679
-
Journey through the thymus: Stromal guides for T cell development and selection
-
Takahama, Y. (2006) Journey through the thymus: stromal guides for T cell development and selection. Nat. Rev. Immunol. 6, 127-135
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 127-135
-
-
Takahama, Y.1
-
2
-
-
37549010335
-
Launching the T cell lineage developmental program
-
Rothenberg, E. V., Moore, J. E., and Yui, M. A. (2008) Launching the T cell lineage developmental program. Nat. Rev. Immunol. 8, 9-21
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 9-21
-
-
Rothenberg, E.V.1
Moore, J.E.2
Yui, M.A.3
-
3
-
-
77954901331
-
Decision checkpoints in the thymus
-
Carpenter, A. C., and Bosselut, R. (2010) Decision checkpoints in the thymus. Nat. Immunol. 11, 666-673
-
(2010)
Nat. Immunol.
, vol.11
, pp. 666-673
-
-
Carpenter, A.C.1
Bosselut, R.2
-
4
-
-
77955980689
-
Positive selection of T cells, an in vitro view
-
Dervovi, D., and Zúñiga-Pflücker, J. C. (2010) Positive selection of T cells, an in vitro view. Semin. Immunol. 22, 276-286
-
(2010)
Semin. Immunol.
, vol.22
, pp. 276-286
-
-
Dervovi, D.1
Zúñiga-Pflücker, J.C.2
-
5
-
-
0030963615
-
Structure and function of the pre-T cell receptor
-
von Boehmer, H., and Fehling, H. J. (1997) Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15, 433-452
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 433-452
-
-
Von Boehmer, H.1
Fehling, H.J.2
-
6
-
-
21844440323
-
Unique features of the pre-T cell receptor α-chain: Not just a surrogate
-
von Boehmer, H. (2005) Unique features of the pre-T cell receptor α-chain: not just a surrogate. Nat. Rev. Immunol. 5, 571-577
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 571-577
-
-
Von Boehmer, H.1
-
7
-
-
0041428109
-
Surface expression of Notch1 on thymocytes: Correlation with the double-negative to double-positive transition
-
Huang, E. Y., Gallegos, A. M., Richards, S. M., Lehar, S. M., and Bevan, M. J. (2003) Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition. J. Immunol. 171, 2296-2304 (Pubitemid 37025534)
-
(2003)
Journal of Immunology
, vol.171
, Issue.5
, pp. 2296-2304
-
-
Huang, E.Y.1
Gallegos, A.M.2
Richards, S.M.3
Lehar, S.M.4
Bevan, M.J.5
-
8
-
-
2142654263
-
Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation
-
Ciofani, M., Schmitt, T. M., Ciofani, A., Michie, A. M., Cuburu, N., Aublin, A., Maryanski, J. L., and Zúñiga-Pflücker, J. C. (2004) Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation. J. Immunol. 172, 5230-5239 (Pubitemid 38542020)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5230-5239
-
-
Ciofani, M.1
Schmitt, T.M.2
Ciofani, A.3
Michie, A.M.4
Cuburu, N.5
Aublin, A.6
Maryanski, J.L.7
Zuniga-Pflucker, J.C.8
-
9
-
-
40549107082
-
In vitro human T cell development directed by Notch-ligand interactions
-
Awong, G., La Motte-Mohs, R. N., and Zúñiga-Pflücker, J. (2008) In vitro human T cell development directed by Notch-ligand interactions. Methods Mol. Biol. 430, 135-142
-
(2008)
Methods Mol. Biol.
, vol.430
, pp. 135-142
-
-
Awong, G.1
La Motte-Mohs, R.N.2
Zúñiga-Pflücker, J.3
-
10
-
-
0347089094
-
T cell development made simple
-
Zúñiga-Pflücker, J. C. (2004) T cell development made simple. Nat. Rev. Immunol. 4, 67-72
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 67-72
-
-
Zúñiga-Pflücker, J.C.1
-
11
-
-
33645050124
-
T cell development, doing it in a dish
-
Schmitt, T. M., and Zúñiga-Pflücker, J. C. (2006) T cell development, doing it in a dish. Immunol. Rev. 209, 95-102
-
(2006)
Immunol. Rev.
, vol.209
, pp. 95-102
-
-
Schmitt, T.M.1
Zúñiga-Pflücker, J.C.2
-
12
-
-
0029794831
-
Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7
-
Bolotin, E., Smogorzewska, M., Smith, S., Widmer, M., and Weinberg, K. (1996) Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood 88, 1887-1894 (Pubitemid 26307089)
-
(1996)
Blood
, vol.88
, Issue.5
, pp. 1887-1894
-
-
Bolotin, E.1
Smogorzewska, M.2
Smith, S.3
Widmer, M.4
Weinberg, K.5
-
13
-
-
0035253734
-
IL-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice
-
Andrew, D., and Aspinall, R. (2001) IL-7 and not stem cell factor reverses both the increase in apoptosis and the decline in thymopoiesis seen in aged mice. J. Immunol. 166, 1524-1530 (Pubitemid 32114631)
-
(2001)
Journal of Immunology
, vol.166
, Issue.3
, pp. 1524-1530
-
-
Andrew, D.1
Aspinall, R.2
-
14
-
-
0036624721
-
Interleukin-7: From bench to clinic
-
DOI 10.1182/blood.V99.11.3892
-
Fry, T. J., and Mackall, C. L. (2002) Interleukin-7: from bench to clinic. Blood 99, 3892-3904 (Pubitemid 35332024)
-
(2002)
Blood
, vol.99
, Issue.11
, pp. 3892-3904
-
-
Fry, T.J.1
Mackall, C.L.2
-
15
-
-
3843124199
-
Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function
-
DOI 10.1182/blood-2003-10-3635
-
Chu, Y. W., Memon, S. A., Sharrow, S. O., Hakim, F. T., Eckhaus, M., Lucas, P. J., and Gress, R. E. (2004) Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function. Blood 104, 1110-1119 (Pubitemid 39038032)
-
(2004)
Blood
, vol.104
, Issue.4
, pp. 1110-1119
-
-
Chu, Y.-W.1
Memon, S.A.2
Sharrow, S.O.3
Hakim, F.T.4
Eckhaus, M.5
Lucas, P.J.6
Gress, R.E.7
-
16
-
-
17844391857
-
Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
-
DOI 10.1080/10428190400027852
-
Barata, J. T., Cardoso, A. A., and Boussiotis, V. A. (2005) Interleukin-7 in T cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis? Leuk. Lymphoma 46, 483-495 (Pubitemid 40584864)
-
(2005)
Leukemia and Lymphoma
, vol.46
, Issue.4
, pp. 483-495
-
-
Barata, J.T.1
Cardoso, A.A.2
Boussiotis, V.A.3
-
17
-
-
79955418828
-
Harnessing the biology of IL-7 for therapeutic application
-
Mackall, C. L., Fry, T. J., and Gress, R. E. (2011) Harnessing the biology of IL-7 for therapeutic application. Nat. Rev. Immunol. 11, 330-342
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 330-342
-
-
Mackall, C.L.1
Fry, T.J.2
Gress, R.E.3
-
18
-
-
0029065488
-
Crucial role of the pre-T cell receptor α gene in development of αβ but not γδ T cells
-
Fehling, H. J., Krotkova, A., Saint-Ruf, C., and von Boehmer, H. (1995) Crucial role of the pre-T cell receptor α gene in development of αβ but not γδ T cells. Nature 375, 795-798
-
(1995)
Nature
, vol.375
, pp. 795-798
-
-
Fehling, H.J.1
Krotkova, A.2
Saint-Ruf, C.3
Von Boehmer, H.4
-
19
-
-
0033081225
-
The common cytokine receptor γ-chain and the pre-T cell receptor provide independent but critically overlapping signals in early α/β T cell development
-
Di Santo, J. P., Aifantis, I., Rosmaraki, E., Garcia, C., Feinberg, J., Fehling, H. J., Fischer, A., von Boehmer, H., and Rocha, B. (1999) The common cytokine receptor γ-chain and the pre-T cell receptor provide independent but critically overlapping signals in early α/β T cell development. J. Exp. Med. 189, 563-574
-
(1999)
J. Exp. Med.
, vol.189
, pp. 563-574
-
-
Di Santo, J.P.1
Aifantis, I.2
Rosmaraki, E.3
Garcia, C.4
Feinberg, J.5
Fehling, H.J.6
Fischer, A.7
Von Boehmer, H.8
Rocha, B.9
-
20
-
-
4444284575
-
A dose effect of IL-7 on thymocyte development
-
DOI 10.1182/blood-2004-01-0201
-
El Kassar, N., Lucas, P. J., Klug, D. B., Zamisch, M., Merchant, M., Bare, C. V., Choudhury, B., Sharrow, S. O., Richie, E., Mackall, C. L., and Gress, R. E. (2004) A dose effect of IL-7 on thymocyte development. Blood 104, 1419-1427 (Pubitemid 39166520)
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1419-1427
-
-
El Kassar, N.1
Lucas, P.J.2
Klug, D.B.3
Zamisch, M.4
Merchant, M.5
Bare, C.V.6
Choudhury, B.7
Sharrow, S.O.8
Richie, E.9
Mackall, C.L.10
Gress, R.E.11
-
21
-
-
0027174226
-
+/- precursor cells and blocks the differentiation pathway of TCRαβ cells in fetal thymus organ culture
-
+/- precursor cells and blocks the differentiation pathway of TCRαβ cells in fetal thymus organ culture. J. Immunol. 150, 2706-2716
-
(1993)
J. Immunol.
, vol.150
, pp. 2706-2716
-
-
Plum, J.1
De Smedt, M.2
Leclercq, G.3
-
22
-
-
0036278490
-
Interleukin-7 inhibits pre-T-cell differentiation induced by the pre-T-cell receptor signal and the effect is mimicked by hGM-CSF in hGM-CSF receptor transgenic mice
-
DOI 10.1046/j.1365-2567.2002.01402.x
-
Yasuda, Y., Kaneko, A., Nishijima, I., Miyatake, S., and Arai, K. (2002) Interleukin-7 inhibits pre-T cell differentiation induced by the pre-T cell receptor signal, and the effect is mimicked by hGM-CSF in hGM-CSF receptor transgenic mice. Immunology 106, 212-221 (Pubitemid 34621829)
-
(2002)
Immunology
, vol.106
, Issue.2
, pp. 212-221
-
-
Yasuda, Y.1
Kaneko, A.2
Nishijima, I.3
Miyatake, S.4
Arai, K.-I.5
-
23
-
-
4143151485
-
IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: Impact on thymocyte development
-
DOI 10.1084/jem.20032183
-
Yu, Q., Erman, B., Park, J. H., Feigenbaum, L., and Singer, A. (2004) IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORγt: impact on thymocyte development. J. Exp. Med. 200, 797-803 (Pubitemid 39299465)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.6
, pp. 797-803
-
-
Yu, Q.1
Erman, B.2
Park, J.-H.3
Feigenbaum, L.4
Singer, A.5
-
24
-
-
0028174201
-
-/- mice in the absence of TCR β-chain expression
-
-/- mice in the absence of TCR β-chain expression. Int. Immunol. 6, 995-1001
-
(1994)
Int. Immunol.
, vol.6
, pp. 995-1001
-
-
Shinkai, Y.1
Alt, F.W.2
-
25
-
-
0030886836
-
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
-
DOI 10.1073/pnas.94.18.9797
-
Cheng, A. M., Negishi, I., Anderson, S. J., Chan, A. C., Bolen, J., Loh, D. Y., and Pawson, T. (1997) The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci. U.S.A. 94, 9797-9801 (Pubitemid 27408144)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9797-9801
-
-
Cheng, A.M.1
Negishi, I.2
Anderson, S.J.3
Chan, A.C.4
Bolen, J.5
Loh, D.Y.6
Pawson, T.7
-
26
-
-
0029957040
-
Interleukin-7 receptor-deficient mice lack γδ T cells
-
Maki, K., Sunaga, S., Komagata, Y., Kodaira, Y., Mabuchi, A., Karasuyama, H., Yokomuro, K., Miyazaki, J. I., and Ikuta, K. (1996) Interleukin-7 receptor-deficient mice lack γδ T cells. Proc. Natl. Acad. Sci. U.S.A. 93, 7172-7177
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 7172-7177
-
-
Maki, K.1
Sunaga, S.2
Komagata, Y.3
Kodaira, Y.4
Mabuchi, A.5
Karasuyama, H.6
Yokomuro, K.7
Miyazaki, J.I.8
Ikuta, K.9
-
27
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin-7 receptor-deficient mice
-
Peschon, J. J., Morrissey, P. J., Grabstein, K. H., Ramsdell, F. J., Maraskovsky, E., Gliniak, B. C., Park, L. S., Ziegler, S. F., Williams, D. E., Ware, C. B., Meyer, J. D., and Davison, B. L. (1994) Early lymphocyte expansion is severely impaired in interleukin-7 receptor-deficient mice. J. Exp. Med. 180, 1955-1960
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
Grabstein, K.H.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
Williams, D.E.9
Ware, C.B.10
Meyer, J.D.11
Davison, B.L.12
-
29
-
-
0033136288
-
Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors
-
DOI 10.1016/S1074-7613(00)80052-7
-
Pallard, C., Stegmann, A. P., van Kleffens, T., Smart, F., Venkitaraman, A., and Spits, H. (1999) Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 10, 525-535 (Pubitemid 29262655)
-
(1999)
Immunity
, vol.10
, Issue.5
, pp. 525-535
-
-
Pallard, C.1
Stegmann, A.P.A.2
Van Kleffens, T.3
Smart, F.4
Venkitaraman, A.5
Spits, H.6
-
30
-
-
0029859982
-
Interleukin-7 is a critical growth factor in early human T-cell development
-
Plum, J., De Smedt, M., Leclercq, G., Verhasselt, B., and Vandekerckhove, B. (1996) Interleukin-7 is a critical growth factor in early human T cell development. Blood 88, 4239-4245 (Pubitemid 26399170)
-
(1996)
Blood
, vol.88
, Issue.11
, pp. 4239-4245
-
-
Plum, J.1
De Smedt, M.2
Leclercq, G.3
Verhasselt, B.4
Vandekerckhove, B.5
-
32
-
-
29244457799
-
Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development
-
DOI 10.1038/ni1290, PII N1290
-
Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D. L., Tokunaga, M., and Saito, T. (2006) Mechanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development. Nat. Immunol. 7, 67-75 (Pubitemid 41823870)
-
(2006)
Nature Immunology
, vol.7
, Issue.1
, pp. 67-75
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Ogata, K.4
Sakata-Sogawa, K.5
Hiroshima, M.6
Wiest, D.L.7
Tokunaga, M.8
Saito, T.9
-
33
-
-
0027489782
-
Restoration of early thymocyte differentiation in T-cell receptor β- chain-deficient mutant mice by transmembrane signaling through CD3ε
-
DOI 10.1073/pnas.90.23.11401
-
Levelt, C. N., Mombaerts, P., Iglesias, A., Tonegawa, S., and Eichmann, K. (1993) Restoration of early thymocyte differentiation in T cell receptor β-chain-deficient mutant mice by transmembrane signaling through CD3ε. Proc. Natl. Acad. Sci. U.S.A. 90, 11401-11405 (Pubitemid 23354437)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11401-11405
-
-
Levelt, C.N.1
Mombaerts, P.2
Iglesias, A.3
Tonegawa, S.4
Eichmann, K.5
-
34
-
-
0028203979
-
CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo
-
Jacobs, H., Vandeputte, D., Tolkamp, L., de Vries, E., Borst, J., and Berns, A. (1994) CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo. Eur. J. Immunol. 24, 934-939 (Pubitemid 24093791)
-
(1994)
European Journal of Immunology
, vol.24
, Issue.4
, pp. 934-939
-
-
Jacobs, H.1
Vandeputte, D.2
Tolkamp, L.3
De Vries, E.4
Borst, J.5
Berns, A.6
-
35
-
-
0035500286
-
b spliced isoforms
-
b spliced isoforms. J. Immunol. 167, 5106-5114
-
(2001)
J. Immunol.
, vol.167
, pp. 5106-5114
-
-
Ramiro, A.R.1
Navarro, M.N.2
Carreira, A.3
Carrasco, Y.R.4
De Yébenes, V.G.5
Carrillo, G.6
San Millán, J.L.7
Rubin, B.8
Toribio, M.L.9
-
36
-
-
39649110182
-
Identification of CMS as a cytosolic adaptor of the human pTα chain involved in pre-TCR function
-
DOI 10.1182/blood-2007-06-094938
-
Navarro, M. N., Nusspaumer, G., Fuentes, P., González- García, S., Alcain, J., and Toribio, M. L. (2007) Identification of CMS as a cytosolic adaptor of the human pTα chain involved in pre-TCR function. Blood 110, 4331-4340 (Pubitemid 351377798)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4331-4340
-
-
Navarro, M.N.1
Nusspaumer, G.2
Fuentes, P.3
Gonzalez-Garcia, S.4
Alcain, J.5
Toribio, M.L.6
-
37
-
-
0030889479
-
The interchain disulfide bond between TCRαβ heterodimers on human T cells is not required for TCR-CD3 membrane expression and signal transduction
-
DOI 10.1093/intimm/9.4.615
-
Arnaud, J., Huchenq, A., Vernhes, M. C., Caspar-Bauguil, S., Lenfant, F., Sancho, J., Terhorst, C., and Rubin, B. (1997) The interchain disulfide bond between TCRαβ heterodimers on human T cells is not required for TCR-CD3 membrane expression and signal transduction. Int. Immunol. 9, 615-626 (Pubitemid 27168496)
-
(1997)
International Immunology
, vol.9
, Issue.4
, pp. 615-626
-
-
Arnaud, J.1
Huchenq, A.2
Vernhes, M.-C.3
Caspar-Bauguil, S.4
Lenfant, F.5
Sancho, J.6
Terhorst, C.7
Rubin, B.8
-
38
-
-
33645295218
-
Lipid rafts in T cell receptor signaling
-
Kabouridis, P. S. (2006) Lipid rafts in T cell receptor signaling. Mol. Membr. Biol. 23, 49-57
-
(2006)
Mol. Membr. Biol.
, vol.23
, pp. 49-57
-
-
Kabouridis, P.S.1
-
39
-
-
22744451729
-
Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1
-
DOI 10.1038/sj.gt.3302509
-
Chang, L. J., Liu, X., and He, J. (2005) Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1. Gene Ther. 12, 1133-1144 (Pubitemid 41030619)
-
(2005)
Gene Therapy
, vol.12
, Issue.14
, pp. 1133-1144
-
-
Chang, L.-J.1
Liu, X.2
He, J.3
-
40
-
-
33645229133
-
An effective cancer vaccine modality: Lentiviral modification of dendritic cells expressing multiple cancer-specific antigens
-
Wang, B., He, J., Liu, C., and Chang, L. J. (2006) An effective cancer vaccine modality: lentiviral modification of dendritic cells expressing multiple cancer-specific antigens. Vaccine 24, 3477-3489
-
(2006)
Vaccine
, vol.24
, pp. 3477-3489
-
-
Wang, B.1
He, J.2
Liu, C.3
Chang, L.J.4
-
41
-
-
0029835185
-
Regulation of pre-T cell receptor (pTα-TCRβ) gene expression during human thymic development
-
Ramiro, A. R., Trigueros, C., Márquez, C., San Millán, J. L., and Toribio, M. L. (1996) Regulation of pre-T cell receptor (pTα-TCRβ) gene expression during human thymic development. J. Exp. Med. 184, 519-530 (Pubitemid 26324105)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.2
, pp. 519-530
-
-
Ramiro, A.R.1
Trigueros, C.2
Marquez, C.3
San Millán, J.L.4
Toribio, M.L.5
-
42
-
-
0032890081
-
Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: Suggestion for classification by immunophenotype and T-cell receptor studies
-
DOI 10.1016/S0145-2126(98)00133-7, PII S0145212698001337
-
Burger, R., Hansen-Hagge, T. E., Drexler, H. G., and Gramatzki, M. (1999) Heterogeneity of T-acute lymphoblastic leukemia (T-ALL) cell lines: suggestion for classification by immunophenotype and T cell receptor studies. Leukemia Res. 23, 19-27 (Pubitemid 28484864)
-
(1999)
Leukemia Research
, vol.23
, Issue.1
, pp. 19-27
-
-
Burger, R.1
Hansen-Hagge, T.E.2
Drexler, H.G.3
Gramatzki, M.4
-
43
-
-
0026529624
-
T cell receptor Vβ variable gene family expression in human peripheral blood lymphocytes at the mRNA and membrane protein levels
-
Hu, H. Z., de Weger, R. A., Bosboom-Kalsbeek, K., Tilanus, M. G., Rozing, J., and Schuurman, H. J. (1992) T cell receptor Vβ variable gene family expression in human peripheral blood lymphocytes at the mRNA and membrane protein levels. Clin. Exp. Immunol. 88, 335-340
-
(1992)
Clin. Exp. Immunol.
, vol.88
, pp. 335-340
-
-
Hu, H.Z.1
De Weger, R.A.2
Bosboom-Kalsbeek, K.3
Tilanus, M.G.4
Rozing, J.5
Schuurman, H.J.6
-
44
-
-
57249094258
-
Human intrathymic development: A selective approach
-
Plum, J., De Smedt, M., Leclercq, G., Taghon, T., Kerre, T., and Vandekerckhove, B. (2008) Human intrathymic development: a selective approach. Semin. Immunopathol. 30, 411-423
-
(2008)
Semin. Immunopathol.
, vol.30
, pp. 411-423
-
-
Plum, J.1
De Smedt, M.2
Leclercq, G.3
Taghon, T.4
Kerre, T.5
Vandekerckhove, B.6
-
45
-
-
22544452762
-
Cell biology of IL-7, a key lymphotrophin
-
DOI 10.1016/j.cytogfr.2005.05.004, PII S1359610105000626
-
Jiang, Q., Li, W. Q., Aiello, F. B., Mazzucchelli, R., Asefa, B., Khaled, A. R., and Durum, S. K. (2005) Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev. 16, 513-533 (Pubitemid 41022015)
-
(2005)
Cytokine and Growth Factor Reviews
, vol.16
, Issue.4-5
, pp. 513-533
-
-
Jiang, Q.1
Wen, Q.L.2
Aiello, F.B.3
Mazzucchelli, R.4
Asefa, B.5
Khaled, A.R.6
Durum, S.K.7
-
46
-
-
33846632842
-
Interleukin-7 receptor expression: Intelligent design
-
DOI 10.1038/nri2023, PII NRI2023
-
Mazzucchelli, R., and Durum, S. K. (2007) Interleukin-7 receptor expression: intelligent design. Nat. Rev. Immunol. 7, 144-154 (Pubitemid 46178275)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.2
, pp. 144-154
-
-
Mazzucchelli, R.1
Durum, S.K.2
-
47
-
-
77951493183
-
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Rα in T cells
-
Henriques, C. M., Rino, J., Nibbs, R. J., Graham, G. J., and Barata, J. T. (2010) IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Rα in T cells. Blood 115, 3269-3277
-
(2010)
Blood
, vol.115
, pp. 3269-3277
-
-
Henriques, C.M.1
Rino, J.2
Nibbs, R.J.3
Graham, G.J.4
Barata, J.T.5
-
48
-
-
0026533216
-
Multiparametric flow cytometric analysis of the kinetics of surface molecule expression after polyclonal activation of human peripheral blood T lymphocytes
-
Biselli, R., Matricardi, P. M., D'Amelio, R., and Fattorossi, A. (1992) Multiparametric flow cytometric analysis of the kinetics of surface molecule expression after polyclonal activation of human peripheral blood T lymphocytes. Scand. J. Immunol. 35, 439-447
-
(1992)
Scand. J. Immunol.
, vol.35
, pp. 439-447
-
-
Biselli, R.1
Matricardi, P.M.2
D'Amelio, R.3
Fattorossi, A.4
-
49
-
-
0036359608
-
Transgenic analysis of thymocyte signal transduction
-
Cantrell, D. A. (2002) Transgenic analysis of thymocyte signal transduction. Nat. Rev. Immunol. 2, 20-27
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 20-27
-
-
Cantrell, D.A.1
-
50
-
-
40149099723
-
Critical roles of the PI3K/Akt signaling pathway in T cell development
-
Juntilla, M. M., and Koretzky, G. A. (2008) Critical roles of the PI3K/Akt signaling pathway in T cell development. Immunol. Lett. 116, 104-110
-
(2008)
Immunol. Lett.
, vol.116
, pp. 104-110
-
-
Juntilla, M.M.1
Koretzky, G.A.2
-
51
-
-
58149347261
-
The role of the PI3K-Akt kinase pathway in T cell development beyond the β checkpoint
-
Xue, L., Chiang, L., Kang, C., and Winoto, A. (2008) The role of the PI3K-Akt kinase pathway in T cell development beyond the β checkpoint. Eur. J. Immunol. 38, 3200-3207
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3200-3207
-
-
Xue, L.1
Chiang, L.2
Kang, C.3
Winoto, A.4
-
52
-
-
79959879513
-
TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase Cα
-
Yang, L., Qiao, G., Ying, H., Zhang, J., and Yin, F. (2010) TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase Cα. Biochem. Biophys. Res. Commun. 400, 16-20
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.400
, pp. 16-20
-
-
Yang, L.1
Qiao, G.2
Ying, H.3
Zhang, J.4
Yin, F.5
-
53
-
-
34247627902
-
Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition
-
Mao, C., Tili, E. G., Dose, M., Haks, M. C., Bear, S. E., Maroulakou, I., Horie, K., Gaitanaris, G. A., Fidanza, V., Ludwig, T., Wiest, D. L., Gounari, F., and Tsichlis, P. N. (2007) Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J. Immunol. 178, 5443-5453 (Pubitemid 46674338)
-
(2007)
Journal of Immunology
, vol.178
, Issue.9
, pp. 5443-5453
-
-
Mao, C.1
Till, E.G.2
Dose, M.3
Haks, M.C.4
Bear, S.E.5
Maroulakou, I.6
Horie, K.7
Gaitanaris, G.A.8
Fidanza, V.9
Ludwig, T.10
Wiest, D.L.11
Gounari, F.12
Tsichlis, P.N.13
-
54
-
-
0029556980
-
Cloning and comparative analysis of the human pre-T cell receptor α-chain gene
-
Del Porto, P., Bruno, L., Mattei, M. G., von Boehmer, H., and Saint-Ruf, C. (1995) Cloning and comparative analysis of the human pre-T cell receptor α-chain gene. Proc. Natl. Acad. Sci. U.S.A. 92, 12105-12109
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 12105-12109
-
-
Del Porto, P.1
Bruno, L.2
Mattei, M.G.3
Von Boehmer, H.4
Saint-Ruf, C.5
-
55
-
-
0036776752
-
Regulation of surface expression of the human pre-T cell receptor complex
-
DOI 10.1016/S1044-5323(02)00065-9
-
Carrasco, Y. R., Navarro, M. N., de Yébenes, V. G., Ramiro, A. R., and Toribio, M. L. (2002) Regulation of surface expression of the human pre-T cell receptor complex. Semin. Immunol. 14, 325-334 (Pubitemid 35015078)
-
(2002)
Seminars in Immunology
, vol.14
, Issue.5
, pp. 325-334
-
-
Carrasco, Y.R.1
Navarro, M.N.2
De Yebenes, V.G.3
Ramiro, A.R.4
Toribio, M.L.5
-
56
-
-
0030602798
-
The map kinase pathway controls differentiation from double-negative to double-positive thymocyte
-
DOI 10.1016/S0092-8674(00)80096-3
-
Crompton, T., Gilmour, K. C., and Owen, M. J. (1996) The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86, 243-251 (Pubitemid 26286107)
-
(1996)
Cell
, vol.86
, Issue.2
, pp. 243-251
-
-
Crompton, T.1
Gilmour, K.C.2
Owen, M.J.3
-
57
-
-
0031749260
-
T cell development and activation in Jak3-deficient mice
-
Baird, A. M., Thomis, D. C., and Berg, L. J. (1998) T cell development and activation in Jak3-deficient mice. J. Leukoc. Biol. 63, 669-677 (Pubitemid 28274827)
-
(1998)
Journal of Leukocyte Biology
, vol.63
, Issue.6
, pp. 669-677
-
-
Baird, A.M.1
Thomis, D.C.2
Berg, L.J.3
-
59
-
-
2442710342
-
Jak3-independent trafficking of the common γ chain receptor subunit: Chaperone function of Jaks revisited
-
DOI 10.1128/MCB.24.11.5039-5049.2004
-
Hofmann, S. R., Lam, A. Q., Frank, S., Zhou, Y. J., Ramos, H. L., Kanno, Y., Agnello, D., Youle, R. J., and O'Shea, J. J. (2004) Jak3-independent trafficking of the common γ-chain receptor subunit: chaperone function of Jaks revisited. Mol. Cell. Biol. 24, 5039-5049 (Pubitemid 38668065)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.11
, pp. 5039-5049
-
-
Hofmann, S.R.1
Lam, A.Q.2
Frank, S.3
Zhou, Y.-J.4
Ramos, H.L.5
Kanno, Y.6
Agnello, D.7
Youle, R.J.8
O'Shea, J.J.9
-
60
-
-
77949527142
-
Acute T cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss
-
Medyouf, H., Gao, X., Armstrong, F., Gusscott, S., Liu, Q., Gedman, A. L., Matherly, L. H., Schultz, K. R., Pflumio, F., You, M. J., and Weng, A. P. (2010) Acute T cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss. Blood 115, 1175-1184
-
(2010)
Blood
, vol.115
, pp. 1175-1184
-
-
Medyouf, H.1
Gao, X.2
Armstrong, F.3
Gusscott, S.4
Liu, Q.5
Gedman, A.L.6
Matherly, L.H.7
Schultz, K.R.8
Pflumio, F.9
You, M.J.10
Weng, A.P.11
-
61
-
-
78650665158
-
Imaging T cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment
-
Yudushkin, I. A., and Vale, R. D. (2010) Imaging T cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment. Proc. Natl. Acad. Sci. U.S.A. 107, 22128-22133
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 22128-22133
-
-
Yudushkin, I.A.1
Vale, R.D.2
-
62
-
-
0035525783
-
Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T cell lymphoma cells
-
Qin, J. Z., Zhang, C. L., Kamarashev, J., Dummer, R., Burg, G., and Döbbeling, U. (2001) Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T cell lymphoma cells. Blood 98, 2778-2783
-
(2001)
Blood
, vol.98
, pp. 2778-2783
-
-
Qin, J.Z.1
Zhang, C.L.2
Kamarashev, J.3
Dummer, R.4
Burg, G.5
Döbbeling, U.6
-
63
-
-
0025947144
-
A conformational epitope expressed upon association of CD3α with either CD3δ or CD3γ is the main target for recognition by anti-CD3 monoclonal antibodies
-
Salmerón, A., Sánchez-Madrid, F., Ursa, M. A., Fresno, M., and Alarcón, B. (1991) A conformational epitope expressed upon association of CD3α with either CD3δ or CD3γ is the main target for recognition by anti-CD3 monoclonal antibodies. J. Immunol. 147, 3047-3052
-
(1991)
J. Immunol.
, vol.147
, pp. 3047-3052
-
-
Salmerón, A.1
Sánchez-Madrid, F.2
Ursa, M.A.3
Fresno, M.4
Alarcón, B.5
-
64
-
-
0030694310
-
Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3δ is physically associated but not functionally required
-
DOI 10.1084/jem.186.9.1461
-
Berger, M. A., Davé, V., Rhodes, M. R., Bosma, G. C., Bosma, M. J., Kappes, D. J., and Wiest, D. L. (1997) Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3δ is physically associated but not functionally required. J. Exp. Med. 186, 1461-1467 (Pubitemid 27479805)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.9
, pp. 1461-1467
-
-
Berger, M.A.1
Dave, V.2
Rhodes, M.R.3
Bosma, G.C.4
Bosma, M.J.5
Kappes, D.J.6
Wiest, D.L.7
-
65
-
-
0033103099
-
Interleukin-7: Physiological roles and mechanisms of action
-
DOI 10.1016/S1359-6101(98)00025-2, PII S1359610198000252
-
Hofmeister, R., Khaled, A. R., Benbernou, N., Rajnavolgyi, E., Muegge, K., and Durum, S. K. (1999) Interleukin-7: physiological roles and mechanisms of action. Cytokine Growth Factor Rev. 10, 41-60 (Pubitemid 29230851)
-
(1999)
Cytokine and Growth Factor Reviews
, vol.10
, Issue.1
, pp. 41-60
-
-
Hofmeister, R.1
Khaled, A.R.2
Benbernou, N.3
Rajnavolgyi, E.4
Muegge, K.5
Durum, S.K.6
-
66
-
-
0041752396
-
Cooperation between IL-7 and the pre-B cell receptor: A key to B cell selection
-
Fleming, H. E., and Paige, C. J. (2002) Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection. Semin. Immunol. 14, 423-430
-
(2002)
Semin. Immunol.
, vol.14
, pp. 423-430
-
-
Fleming, H.E.1
Paige, C.J.2
-
67
-
-
50949110014
-
IL-7 activates the phosphatidylinositol 3-kinase/Akt pathway in normal human thymocytes but not normal human B cell precursors
-
Johnson, S. E., Shah, N., Bajer, A. A., and LeBien, T. W. (2008) IL-7 activates the phosphatidylinositol 3-kinase/Akt pathway in normal human thymocytes but not normal human B cell precursors. J. Immunol. 180, 8109-8117
-
(2008)
J. Immunol.
, vol.180
, pp. 8109-8117
-
-
Johnson, S.E.1
Shah, N.2
Bajer, A.A.3
LeBien, T.W.4
-
68
-
-
10744230130
-
IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL
-
DOI 10.1182/blood-2002-12-3861
-
Barata, J. T., Boussiotis, V. A., Yunes, J. A., Ferrando, A. A., Moreau, L. A., Veiga, J. P., Sallan, S. E., Look, A. T., Nadler, L. M., and Cardoso, A. A. (2004) IL-7-dependent human leukemia T cell line as a valuable tool for drug discovery in T-ALL. Blood 103, 1891-1900 (Pubitemid 38268988)
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1891-1900
-
-
Barata, J.T.1
Boussiotis, V.A.2
Yunes, J.A.3
Ferrando, A.A.4
Moreau, L.A.5
Veiga, J.P.6
Sallan, S.E.7
Look, A.T.8
Nadler, L.M.9
Cardoso, A.A.10
-
69
-
-
4544331713
-
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells
-
DOI 10.1084/jem.20040789
-
Barata, J. T., Silva, A., Brandao, J. G., Nadler, L. M., Cardoso, A. A., and Boussiotis, V. A. (2004) Activation of PI3K is indispensable for interleukin-7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. J. Exp. Med. 200, 659-669 (Pubitemid 39258314)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.5
, pp. 659-669
-
-
Barata, J.T.1
Silva, A.2
Brandao, J.G.3
Nadler, L.M.4
Cardoso, A.A.5
Boussiotis, V.A.6
-
70
-
-
0031757825
-
Role of interleukin-7 in T-cell development from hematopoietic stem cells
-
Akashi, K., Kondo, M., and Weissman, I. L. (1998) Role of interleukin-7 in T cell development from hematopoietic stem cells. Immunol. Rev. 165, 13-28 (Pubitemid 28524199)
-
(1998)
Immunological Reviews
, vol.165
, pp. 13-28
-
-
Akashi, K.1
Kondo, M.2
Weissman, I.L.3
-
71
-
-
10244243681
-
Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis
-
DOI 10.1182/blood-2004-06-2484
-
Munitic, I., Williams, J. A., Yang, Y., Dong, B., Lucas, P. J., El Kassar, N., Gress, R. E., and Ashwell, J. D. (2004) Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis. Blood 104, 4165-4172 (Pubitemid 39620170)
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4165-4172
-
-
Munitic, I.1
Williams, J.A.2
Yang, Y.3
Dong, B.4
Lucas, P.J.5
El Kassar, N.6
Gress, R.E.7
Ashwell, J.D.8
-
72
-
-
77950524945
-
Differential IL-7 responses in developing human thymocytes
-
Marino, J. H., Tan, C., Taylor, A. A., Bentley, C., Van De Wiele, C. J., Ranne, R., Paliotta, M., Broughan, T. A., and Teague, T. K. (2010) Differential IL-7 responses in developing human thymocytes. Hum. Immunol. 71, 329-333
-
(2010)
Hum. Immunol.
, vol.71
, pp. 329-333
-
-
Marino, J.H.1
Tan, C.2
Taylor, A.A.3
Bentley, C.4
Van De Wiele, C.J.5
Ranne, R.6
Paliotta, M.7
Broughan, T.A.8
Teague, T.K.9
-
73
-
-
84864924604
-
Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation
-
Patel, E. S., Okada, S., Hachey, K., Yang, L.-J., Durum, S. K., Moreb, J. S., and Chang, L.-J. (2012) Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation. BMC Immunol. 13, 46
-
(2012)
BMC Immunol.
, vol.13
, pp. 46
-
-
Patel, E.S.1
Okada, S.2
Hachey, K.3
Yang, L.-J.4
Durum, S.K.5
Moreb, J.S.6
Chang, L.-J.7
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