Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 51, 2010, Pages 22128-22133

  Yudushkin, Ivan A ^a   Vale, Ronald D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

F rster's resonant energy transfer; Lck kinase; Receptor trafficking

Indexed keywords

CD3 ANTIGEN; CD3ZETA ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL VACUOLE; ENDOSOME; ENZYME ACTIVITY; INTERNALIZATION; LEUKEMIA CELL LINE; MOLECULAR IMAGING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANTIGENS, CD3; ENDOSOMES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELLS; HUMANS; JURKAT CELLS; LYSOSOMES; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TYROSINE;

EID: 78650665158     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016388108     Document Type: Article

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