-
1
-
-
17344362313
-
Ligand recognition by alpha beta T cell receptors
-
Davis MM, Boniface JJ, Reich Z, Lyons D, Hampl J, Arden B, Chien Y. Ligand recognition by alpha beta T cell receptors. Annu Rev Immunol 1998;16:523-544.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 523-544
-
-
Davis, M.M.1
Boniface, J.J.2
Reich, Z.3
Lyons, D.4
Hampl, J.5
Arden, B.6
Chien, Y.7
-
2
-
-
0027399703
-
Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain
-
Irving BA, Chan AC, Weiss A. Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med 1993;177:1093-1103.
-
(1993)
J Exp Med
, vol.177
, pp. 1093-1103
-
-
Irving, B.A.1
Chan, A.C.2
Weiss, A.3
-
3
-
-
0028986925
-
CD3ε and CD3ζ cytoplasmic domains can independently generate signals for T cell development and function
-
Shinkai Y, Ma A, Cheng H-L, Alt FW. CD3ε and CD3ζ cytoplasmic domains can independently generate signals for T cell development and function. Immunity 1995;2:401-411.
-
(1995)
Immunity
, vol.2
, pp. 401-411
-
-
Shinkai, Y.1
Ma, A.2
Cheng, H.-L.3
Alt, F.W.4
-
4
-
-
0023737931
-
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
-
Veillette A, Bookman MA, Horak EM, Bolen JB. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. Cell 1988;55:301-308.
-
(1988)
Cell
, vol.55
, pp. 301-308
-
-
Veillette, A.1
Bookman, M.A.2
Horak, E.M.3
Bolen, J.B.4
-
5
-
-
0029874657
-
T cell antigen receptor signal transduction pathways
-
Cantrell D. T cell antigen receptor signal transduction pathways. Annu Rev Immunol 1996;14:259-274.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 259-274
-
-
Cantrell, D.1
-
6
-
-
0035367576
-
Proximal protein tyrosine kinases in immunoreceptor signaling
-
Latour S, Veillette A. Proximal protein tyrosine kinases in immunoreceptor signaling. Curr Opin Immunol 2001;13:299-306.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 299-306
-
-
Latour, S.1
Veillette, A.2
-
7
-
-
0026522204
-
Profound block in thymocyte development in mice lacking p56lck
-
Molina TJ, Kishihara K, Siderovski DP, van Ewijk W, Narendran A, Timms E, Wakeham A, Paige CJ, Hartmann KU, Veillette A. Profound block in thymocyte development in mice lacking p56lck. Nature 1992;357:161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.U.9
Veillette, A.10
-
8
-
-
0026612411
-
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
-
Stein PL, Lee H-M, Rich S, Soriano P. pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 1992;70:741-750.
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.-M.2
Rich, S.3
Soriano, P.4
-
9
-
-
0026705903
-
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
-
Straus DB, Weiss A. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 1992;70:585-593.
-
(1992)
Cell
, vol.70
, pp. 585-593
-
-
Straus, D.B.1
Weiss, A.2
-
10
-
-
0027296521
-
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
-
Kishihara K, Penninger J, Wallace VA, Kundig TM, Kawai K, Wakeham A, Timms E, Pfeffer K, Ohashi PS, Thomas ML, et al. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell 1993;74:143-156.
-
(1993)
Cell
, vol.74
, pp. 143-156
-
-
Kishihara, K.1
Penninger, J.2
Wallace, V.A.3
Kundig, T.M.4
Kawai, K.5
Wakeham, A.6
Timms, E.7
Pfeffer, K.8
Ohashi, P.S.9
Thomas, M.L.10
-
11
-
-
0025297050
-
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyinositol pathway
-
Koretzky GA, Picus J, Thomas ML, Weiss A. Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyinositol pathway. Nature 1990;346:66-68.
-
(1990)
Nature
, vol.346
, pp. 66-68
-
-
Koretzky, G.A.1
Picus, J.2
Thomas, M.L.3
Weiss, A.4
-
12
-
-
0025303196
-
Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45)
-
Mustelin T, Altman A. Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45). Oncogene 1990;5:809-813.
-
(1990)
Oncogene
, vol.5
, pp. 809-813
-
-
Mustelin, T.1
Altman, A.2
-
13
-
-
0026483786
-
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
-
Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell 1992;71:649-662.
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
14
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE. LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998;92:83-92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
15
-
-
0034675889
-
Selective accumulation of raft-associated membrane protein LAT in T cell receptor signaling assemblies
-
Harder T, Kuhn M. Selective accumulation of raft-associated membrane protein LAT in T cell receptor signaling assemblies. J Cell Biol 2000;151:199-208.
-
(2000)
J Cell Biol
, vol.151
, pp. 199-208
-
-
Harder, T.1
Kuhn, M.2
-
16
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997;387:569-572.
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
17
-
-
0030822255
-
Lipid microdomains in cell surface membranes
-
Edidin M. Lipid microdomains in cell surface membranes. Curr Opin Struct Biol 1997;7:528-532.
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 528-532
-
-
Edidin, M.1
-
18
-
-
0032421354
-
Functions of lipid rafts in biological membranes
-
Brown DA, London E. Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 1998;14:111-136.
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 111-136
-
-
Brown, D.A.1
London, E.2
-
20
-
-
0031965054
-
Sphingolipid organization in biomembranes: What physical studies of model membranes reveal
-
Brown RE. Sphingolipid organization in biomembranes: what physical studies of model membranes reveal. J Cell Sci 1998;111:1-9.
-
(1998)
J Cell Sci
, vol.111
, pp. 1-9
-
-
Brown, R.E.1
-
21
-
-
0344585437
-
Lipid rafts: Elusive or illusive?
-
Munro S. Lipid rafts: elusive or illusive? Cell 2003;115:377-388.
-
(2003)
Cell
, vol.115
, pp. 377-388
-
-
Munro, S.1
-
22
-
-
0036841874
-
Triton promotes domain formation in lipid raft mixtures
-
Heerklotz H. Triton promotes domain formation in lipid raft mixtures. Biophys J 2002;83:2693-2701.
-
(2002)
Biophys J
, vol.83
, pp. 2693-2701
-
-
Heerklotz, H.1
-
23
-
-
0037947831
-
Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors
-
USA
-
Foster LJ, De Hoog CL, Mann M. Unbiased quantitative proteomics of lipid rafts reveals high specificity for signaling factors. Proc Natl Acad Sci USA 2003;100:5813-5818.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 5813-5818
-
-
Foster, L.J.1
De Hoog, C.L.2
Mann, M.3
-
24
-
-
0035433580
-
Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains
-
von Haller PD, Donohoe S, Goodlett DR, Aebersold R, Watts JD. Mass spectrometric characterization of proteins extracted from Jurkat T cell detergent-resistant membrane domains. Proteomics 2001;1:1010-1021.
-
(2001)
Proteomics
, vol.1
, pp. 1010-1021
-
-
Von Haller, P.D.1
Donohoe, S.2
Goodlett, D.R.3
Aebersold, R.4
Watts, J.D.5
-
25
-
-
9944248585
-
Regulation of T-cell receptor signalling by membrane microdomains
-
Razzaq TM, Ozegbe P, Jury EC, Sembi P, Blackwell NM, Kabouridis PS. Regulation of T-cell receptor signalling by membrane microdomains. Immunology 2004;113:413-426.
-
(2004)
Immunology
, vol.113
, pp. 413-426
-
-
Razzaq, T.M.1
Ozegbe, P.2
Jury, E.C.3
Sembi, P.4
Blackwell, N.M.5
Kabouridis, P.S.6
-
26
-
-
0035059418
-
The immunological synapse
-
Bromley SK, Burack WR, Johnson KG, Somersalo K, Sims TN, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML. The immunological synapse. Annu Rev Immunol 2001;19:375-396.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 375-396
-
-
Bromley, S.K.1
Burack, W.R.2
Johnson, K.G.3
Somersalo, K.4
Sims, T.N.5
Sumen, C.6
Davis, M.M.7
Shaw, A.S.8
Allen, P.M.9
Dustin, M.L.10
-
27
-
-
2942662120
-
Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques
-
Murase K, Fujiwara T, Umemura Y, Suzuki K, Iino R, Yamashita H, Saito M, Murakoshi H, Ritchie K, Kusumi A. Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques. Biophys J 2004;86:4075-4093.
-
(2004)
Biophys J
, vol.86
, pp. 4075-4093
-
-
Murase, K.1
Fujiwara, T.2
Umemura, Y.3
Suzuki, K.4
Iino, R.5
Yamashita, H.6
Saito, M.7
Murakoshi, H.8
Ritchie, K.9
Kusumi, A.10
-
28
-
-
0038788003
-
Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single-molecule-fluorescence video imaging
-
Ike H, Kosugi A, Kato A, Iino R, Hirano H, Fujiwara T, Ritchie K, Kusumi A. Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single-molecule-fluorescence video imaging. Chemphyschem 2003;4:620-626.
-
(2003)
Chemphyschem
, vol.4
, pp. 620-626
-
-
Ike, H.1
Kosugi, A.2
Kato, A.3
Iino, R.4
Hirano, H.5
Fujiwara, T.6
Ritchie, K.7
Kusumi, A.8
-
29
-
-
0031452274
-
Structures of Src-family tyrosine kinases
-
Sicheri F, Kuriyan J. Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 1997;7:777-785.
-
(1997)
Curr Opin Struct Biol
, vol.7
, pp. 777-785
-
-
Sicheri, F.1
Kuriyan, J.2
-
30
-
-
0027493485
-
Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl- phosphatidylinositol-anchored proteins
-
Shenoy-Scaria AM, Gauen LKT, Kwong J, Shaw AS, Lublin DM. Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins. Mol Cell Biol 1993;13:6385-6392.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6385-6392
-
-
Shenoy-Scaria, A.M.1
Gauen, L.K.T.2
Kwong, J.3
Shaw, A.S.4
Lublin, D.M.5
-
31
-
-
0028145334
-
Signals determining protein tyrosine kinase and glycosyl- phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction
-
Rodgers W, Crise B, Rose JK. Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction. Mol Cell Biol 1994;14:5384-5391.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5384-5391
-
-
Rodgers, W.1
Crise, B.2
Rose, J.K.3
-
32
-
-
0030746106
-
S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes
-
Kabouridis PS, Magee AI, Ley SC. S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes. EMBO J 1997;16:4983-4998.
-
(1997)
EMBO J
, vol.16
, pp. 4983-4998
-
-
Kabouridis, P.S.1
Magee, A.I.2
Ley, S.C.3
-
33
-
-
0026730381
-
Functional analysis of the SH2 and SH3 domains of the lck tyrosine protein kinase
-
Reynolds PJ, Hurley TR, Sefton BM. Functional analysis of the SH2 and SH3 domains of the lck tyrosine protein kinase. Oncogene 1992;7:1949-1955.
-
(1992)
Oncogene
, vol.7
, pp. 1949-1955
-
-
Reynolds, P.J.1
Hurley, T.R.2
Sefton, B.M.3
-
34
-
-
0033001789
-
Crystal structures of c-Src reveal features of its autoinhibitory mechanism
-
Xu W, Doshi A, Lei M, Eck MJ, Harrison SC. Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol Cell 1999;3:629-638.
-
(1999)
Mol Cell
, vol.3
, pp. 629-638
-
-
Xu, W.1
Doshi, A.2
Lei, M.3
Eck, M.J.4
Harrison, S.C.5
-
35
-
-
16144364951
-
Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation
-
Yamaguchi H, Hendrickson WA. Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation. Nature 1996;384:484-489.
-
(1996)
Nature
, vol.384
, pp. 484-489
-
-
Yamaguchi, H.1
Hendrickson, W.A.2
-
36
-
-
0026681275
-
The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity
-
Bergman M, Mustelin T, Oetken C, Partanen J, Flint NA, Amrein KE, Autero M, Burn P, Alitalo K. The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity. EMBO J 1992;11:2919-2924.
-
(1992)
EMBO J
, vol.11
, pp. 2919-2924
-
-
Bergman, M.1
Mustelin, T.2
Oetken, C.3
Partanen, J.4
Flint, N.A.5
Amrein, K.E.6
Autero, M.7
Burn, P.8
Alitalo, K.9
-
38
-
-
0033558102
-
Cutting edge: The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes
-
D'Oro U, Ashwell JD. Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes. J Immunol 1999;162:1879-1883.
-
(1999)
J Immunol
, vol.162
, pp. 1879-1883
-
-
D'Oro, U.1
Ashwell, J.D.2
-
39
-
-
0036794399
-
Staging and resetting T cell activation in SMACs
-
Freiberg BA, Kupfer H, Maslanik W, Delli J, Kappler J, Zaller DM, Kupfer A. Staging and resetting T cell activation in SMACs. Nat Immunol 2002;3:911-917.
-
(2002)
Nat Immunol
, vol.3
, pp. 911-917
-
-
Freiberg, B.A.1
Kupfer, H.2
Maslanik, W.3
Delli, J.4
Kappler, J.5
Zaller, D.M.6
Kupfer, A.7
-
40
-
-
0033998793
-
The role of lipid rafts in T cell antigen receptor (TCR) signalling
-
Janes PW, Ley SC, Magee AI, Kabouridis PS. The role of lipid rafts in T cell antigen receptor (TCR) signalling. Sem Immunol 2000;12:23-34.
-
(2000)
Sem Immunol
, vol.12
, pp. 23-34
-
-
Janes, P.W.1
Ley, S.C.2
Magee, A.I.3
Kabouridis, P.S.4
-
41
-
-
0037012578
-
The oxygen-substituted palmitic acid analogue, 13-oxypalmitic acid, inhibits Lck localization to lipid rafts and T cell signaling
-
Hawash IY, Hu XE, Adal A, Cassady JM, Geahlen RL, Harrison ML. The oxygen-substituted palmitic acid analogue, 13-oxypalmitic acid, inhibits Lck localization to lipid rafts and T cell signaling. Biochim Biophys Acta 2002;1589:140-150.
-
(2002)
Biochim Biophys Acta
, vol.1589
, pp. 140-150
-
-
Hawash, I.Y.1
Hu, X.E.2
Adal, A.3
Cassady, J.M.4
Geahlen, R.L.5
Harrison, M.L.6
-
42
-
-
0032142953
-
LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
-
Zhang W, Trible RP, Samelson LE. LAT palmitoylation: Its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. Immunity 1998;9:239-246.
-
(1998)
Immunity
, vol.9
, pp. 239-246
-
-
Zhang, W.1
Trible, R.P.2
Samelson, L.E.3
-
43
-
-
10844280748
-
Cutting edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development
-
Zhu M, Shen S, Liu Y, Granillo O, Zhang W. Cutting edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development. J Immunol 2005;174:31-35.
-
(2005)
J Immunol
, vol.174
, pp. 31-35
-
-
Zhu, M.1
Shen, S.2
Liu, Y.3
Granillo, O.4
Zhang, W.5
-
44
-
-
0342313755
-
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
-
Brdicka T, Pavlistova D, Leo A, Bruyns E, Korinek V, Angelisova P, Scherer J, Shevchenko A, Hilgert I, Cerny J, Drbal K, Kuramitsu Y, Kornacker B, Horejsi V, Schraven B. Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 2000;191:1591-1604.
-
(2000)
J Exp Med
, vol.191
, pp. 1591-1604
-
-
Brdicka, T.1
Pavlistova, D.2
Leo, A.3
Bruyns, E.4
Korinek, V.5
Angelisova, P.6
Scherer, J.7
Shevchenko, A.8
Hilgert, I.9
Cerny, J.10
Drbal, K.11
Kuramitsu, Y.12
Kornacker, B.13
Horejsi, V.14
Schraven, B.15
-
45
-
-
0034720166
-
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
-
Kawabuchi M, Satomi Y, Takao T, Shimonishi Y, Nada S, Nagai K, Tarakhovsky A, Okada M. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 2000;404:999-1003.
-
(2000)
Nature
, vol.404
, pp. 999-1003
-
-
Kawabuchi, M.1
Satomi, Y.2
Takao, T.3
Shimonishi, Y.4
Nada, S.5
Nagai, K.6
Tarakhovsky, A.7
Okada, M.8
-
46
-
-
10744225431
-
LIME: A new membrane raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling
-
Brdickova N, Brdicka T, Angelisova P, Horvath O, Spicka J, Hilgert I, Paces J, Simeoni L, Kliche S, Merten C, Schraven B, Horejsi V. LIME: A new membrane raft-associated adaptor protein involved in CD4 and CD8 coreceptor signaling. J Exp Med 2003;198:1453-1462.
-
(2003)
J Exp Med
, vol.198
, pp. 1453-1462
-
-
Brdickova, N.1
Brdicka, T.2
Angelisova, P.3
Horvath, O.4
Spicka, J.5
Hilgert, I.6
Paces, J.7
Simeoni, L.8
Kliche, S.9
Merten, C.10
Schraven, B.11
Horejsi, V.12
-
47
-
-
0345138999
-
LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation
-
Hur EM, Son M, Lee OH, Choi YB, Park C, Lee H, Yun Y. LIME, a novel transmembrane adaptor protein, associates with p56lck and mediates T cell activation. J Exp Med 2003;198:1463-1473.
-
(2003)
J Exp Med
, vol.198
, pp. 1463-1473
-
-
Hur, E.M.1
Son, M.2
Lee, O.H.3
Choi, Y.B.4
Park, C.5
Lee, H.6
Yun, Y.7
-
48
-
-
0030453582
-
Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains
-
Rodgers W, Rose JK. Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains. J Cell Biol 1996;135:1515-1523.
-
(1996)
J Cell Biol
, vol.135
, pp. 1515-1523
-
-
Rodgers, W.1
Rose, J.K.2
-
49
-
-
0033993454
-
Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes
-
Kabouridis PS, Janzen J, Magee AL, Ley SC. Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes. Eur J Immunol 2000;30:954-963.
-
(2000)
Eur J Immunol
, vol.30
, pp. 954-963
-
-
Kabouridis, P.S.1
Janzen, J.2
Magee, A.L.3
Ley, S.C.4
-
50
-
-
0034948374
-
Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts
-
Kosugi A, Sakakura J, Yasuda K, Ogata M, Hamaoka T. Involvement of SHP-1 tyrosine phosphatase in TCR-mediated signaling pathways in lipid rafts. Immunity 2001;14:669-680.
-
(2001)
Immunity
, vol.14
, pp. 669-680
-
-
Kosugi, A.1
Sakakura, J.2
Yasuda, K.3
Ogata, M.4
Hamaoka, T.5
-
51
-
-
0038363406
-
Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells
-
Kabouridis PS. Selective interaction of LAT (linker of activated T cells) with the open-active form of Lck in lipid rafts reveals a new mechanism for the regulation of Lck in T cells. Biochem J 2003;371:907-915.
-
(2003)
Biochem J
, vol.371
, pp. 907-915
-
-
Kabouridis, P.S.1
-
52
-
-
0037133602
-
Negative regulation of Lck by Cbl ubiquitin ligase
-
USA
-
Rao N, Miyake S, Reddi AL, Douillard P, Ghosh AK, Dodge IL, Zhou P, Fernandes ND, Band H. Negative regulation of Lck by Cbl ubiquitin ligase. Proc Natl Acad Sci USA 2002;99:3794-3799.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 3794-3799
-
-
Rao, N.1
Miyake, S.2
Reddi, A.L.3
Douillard, P.4
Ghosh, A.K.5
Dodge, I.L.6
Zhou, P.7
Fernandes, N.D.8
Band, H.9
-
53
-
-
27144509762
-
Regulation of expression and function of Lck tyrosine kinase by high cell density
-
Ozegbe P, Chernajovsky Y, Kabouridis PS. Regulation of expression and function of Lck tyrosine kinase by high cell density. Mol Membr Biol 2005;22:363-372.
-
(2005)
Mol Membr Biol
, vol.22
, pp. 363-372
-
-
Ozegbe, P.1
Chernajovsky, Y.2
Kabouridis, P.S.3
-
54
-
-
0037105622
-
Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells
-
Yasuda K, Nagafuku M, Shima T, Okada M, Yagi T, Yamada T, Minaki Y, Kato A, Tani-Ichi S, Hamaoka T, Kosugi A. Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells. J Immunol 2002;169:2813-2817.
-
(2002)
J Immunol
, vol.169
, pp. 2813-2817
-
-
Yasuda, K.1
Nagafuku, M.2
Shima, T.3
Okada, M.4
Yagi, T.5
Yamada, T.6
Minaki, Y.7
Kato, A.8
Tani-Ichi, S.9
Hamaoka, T.10
Kosugi, A.11
-
55
-
-
0032530369
-
Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
-
Montixi C, Langlet C, Bernard AM, Thimonier J, Dubois C, Wurbel MA, Chauvin JP, Pierres M, He HT. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J 1998;17:5334-5348.
-
(1998)
EMBO J
, vol.17
, pp. 5334-5348
-
-
Montixi, C.1
Langlet, C.2
Bernard, A.M.3
Thimonier, J.4
Dubois, C.5
Wurbel, M.A.6
Chauvin, J.P.7
Pierres, M.8
He, H.T.9
-
56
-
-
0032101348
-
Membrane compartmentation is required for efficient T cell activation
-
Xavier R, Brennan T, Li Q, McCormack C, Seed B. Membrane compartmentation is required for efficient T cell activation. Immunity 1998;8:356-360.
-
(1998)
Immunity
, vol.8
, pp. 356-360
-
-
Xavier, R.1
Brennan, T.2
Li, Q.3
McCormack, C.4
Seed, B.5
-
57
-
-
0742324476
-
Physiological T cell activation starts and propagates in lipid rafts
-
Pizzo P, Giurisato E, Bigsten A, Tassi M, Tavano R, Shaw A, Viola A. Physiological T cell activation starts and propagates in lipid rafts. Immunol Lett 2004;91:3-9.
-
(2004)
Immunol Lett
, vol.91
, pp. 3-9
-
-
Pizzo, P.1
Giurisato, E.2
Bigsten, A.3
Tassi, M.4
Tavano, R.5
Shaw, A.6
Viola, A.7
-
58
-
-
0035800835
-
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts
-
Torgersen KM, Vang T, Abrahamsen H, Yaqub S, Horejsi V, Schraven B, Rolstad B, Mustelin T, Tasken K. Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts. J Biol Chem 2001;276:29313-29318.
-
(2001)
J Biol Chem
, vol.276
, pp. 29313-29318
-
-
Torgersen, K.M.1
Vang, T.2
Abrahamsen, H.3
Yaqub, S.4
Horejsi, V.5
Schraven, B.6
Rolstad, B.7
Mustelin, T.8
Tasken, K.9
-
59
-
-
0037370491
-
Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor
-
Davidson D, Bakinowski M, Thomas ML, Horejsi V, Veillette A. Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor. Mol Cell Biol 2003;23:2017-2028.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2017-2028
-
-
Davidson, D.1
Bakinowski, M.2
Thomas, M.L.3
Horejsi, V.4
Veillette, A.5
-
60
-
-
0037392883
-
Positive and negative regulation of T-cell activation through kinases and phosphatases
-
Mustelin T, Tasken K. Positive and negative regulation of T-cell activation through kinases and phosphatases. Biochem J 2003;371:15-27.
-
(2003)
Biochem J
, vol.371
, pp. 15-27
-
-
Mustelin, T.1
Tasken, K.2
-
61
-
-
0034948337
-
The TCR triggering puzzle
-
van der Merwe PA. The TCR triggering puzzle. Immunity 2001;14:665-668.
-
(2001)
Immunity
, vol.14
, pp. 665-668
-
-
Van Der Merwe, P.A.1
-
62
-
-
0037318863
-
CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling
-
Irles C, Symons A, Michel F, Bakker TR, van der Merwe PA, Acuto O. CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling. Nat Immunol 2003;4:189-197.
-
(2003)
Nat Immunol
, vol.4
, pp. 189-197
-
-
Irles, C.1
Symons, A.2
Michel, F.3
Bakker, T.R.4
Van Der Merwe, P.A.5
Acuto, O.6
-
63
-
-
0036839104
-
Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes
-
Edmonds SD, Ostergaard HL. Dynamic association of CD45 with detergent-insoluble microdomains in T lymphocytes. J Immunol 2002;169:5036-5042.
-
(2002)
J Immunol
, vol.169
, pp. 5036-5042
-
-
Edmonds, S.D.1
Ostergaard, H.L.2
-
64
-
-
2142710163
-
Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythema tosus
-
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA. Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythema tosus. J Clin Invest 2004;113:1176-1187.
-
(2004)
J Clin Invest
, vol.113
, pp. 1176-1187
-
-
Jury, E.C.1
Kabouridis, P.S.2
Flores-Borja, F.3
Mageed, R.A.4
Isenberg, D.A.5
-
65
-
-
2942586874
-
Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus
-
Krishnan S, Nambiar MP, Warke VG, Fisher CU, Mitchell J, Delaney N, Tsokos GC. Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus. J Immunol 2004;172:7821-7831.
-
(2004)
J Immunol
, vol.172
, pp. 7821-7831
-
-
Krishnan, S.1
Nambiar, M.P.2
Warke, V.G.3
Fisher, C.U.4
Mitchell, J.5
Delaney, N.6
Tsokos, G.C.7
-
66
-
-
3142706505
-
T lymphocyte signalling in systemic lupus erythematosus: A lipid raft perspective
-
Jury EC, Kabouridis PS. T lymphocyte signalling in systemic lupus erythematosus: A lipid raft perspective. Lupus 2004;13:413-422.
-
(2004)
Lupus
, vol.13
, pp. 413-422
-
-
Jury, E.C.1
Kabouridis, P.S.2
-
67
-
-
0032727709
-
Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor
-
Janes PW, Ley SC, Magee AI. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor. J Cell Biol 1999;147:447-461.
-
(1999)
J Cell Biol
, vol.147
, pp. 447-461
-
-
Janes, P.W.1
Ley, S.C.2
Magee, A.I.3
-
68
-
-
0037090529
-
TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts
-
Drevot P, Langlet C, Guo XJ, Bernard AM, Colard O, Chauvin JP, Lasserre R, He HT. TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts. EMBO J 2002;21:1899-1908.
-
(2002)
EMBO J
, vol.21
, pp. 1899-1908
-
-
Drevot, P.1
Langlet, C.2
Guo, X.J.3
Bernard, A.M.4
Colard, O.5
Chauvin, J.P.6
Lasserre, R.7
He, H.T.8
-
69
-
-
0037133049
-
p56Lck anchors CD4 to distinct microdomains on microvilli
-
USA
-
Foti M, Phelouzat MA, Holm A, Rasmusson BJ, Carpentier JL. p56Lck anchors CD4 to distinct microdomains on microvilli. Proc Natl Acad Sci USA 2002;99:2008-2013.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 2008-2013
-
-
Foti, M.1
Phelouzat, M.A.2
Holm, A.3
Rasmusson, B.J.4
Carpentier, J.L.5
-
70
-
-
0037438349
-
Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling
-
Fragoso R, Ren D, Zhang X, Su MW, Burakoff SJ, Jin YJ. Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J Immunol 2003;170:913-921.
-
(2003)
J Immunol
, vol.170
, pp. 913-921
-
-
Fragoso, R.1
Ren, D.2
Zhang, X.3
Su, M.W.4
Burakoff, S.J.5
Jin, Y.J.6
-
71
-
-
2442494090
-
CD4 raft association and signaling regulate molecular clustering at the immunological synapse site
-
Balamuth F, Brogdon JL, Bottomly K. CD4 raft association and signaling regulate molecular clustering at the immunological synapse site. J Immunol 2004;172:5887-5892.
-
(2004)
J Immunol
, vol.172
, pp. 5887-5892
-
-
Balamuth, F.1
Brogdon, J.L.2
Bottomly, K.3
-
72
-
-
0037069384
-
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation
-
USA
-
Kovacs B, Maus MV, Riley JL, Derimanov GS, Koretzky GA, June CH, Finkel TH. Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation. Proc Natl Acad Sci USA 2002;99:15006-15011.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 15006-15011
-
-
Kovacs, B.1
Maus, M.V.2
Riley, J.L.3
Derimanov, G.S.4
Koretzky, G.A.5
June, C.H.6
Finkel, T.H.7
-
73
-
-
0344458247
-
T-cell receptor-CD4 physical association in a murine T-cell hybridoma: Induction by antigen receptor ligation
-
USA
-
Mittler RS, Goldman SJ, Spitalny GL, Burakoff SJ. T-cell receptor-CD4 physical association in a murine T-cell hybridoma: induction by antigen receptor ligation. Proc Natl Acad Sci USA 1989;86:8531-8535.
-
(1989)
Proc Natl Acad Sci
, vol.86
, pp. 8531-8535
-
-
Mittler, R.S.1
Goldman, S.J.2
Spitalny, G.L.3
Burakoff, S.J.4
-
74
-
-
0036195934
-
Regulation of Lck activity by CD4 and CD28 in the immunological synapse
-
Holdorf AD, Lee KH, Burack WR, Allen PM, Shaw AS. Regulation of Lck activity by CD4 and CD28 in the immunological synapse. Nat Immunol 2002;3:259-264.
-
(2002)
Nat Immunol
, vol.3
, pp. 259-264
-
-
Holdorf, A.D.1
Lee, K.H.2
Burack, W.R.3
Allen, P.M.4
Shaw, A.S.5
-
75
-
-
0032986671
-
Membrane compartmentation and the response to antigen
-
Xavier R, Seed B. Membrane compartmentation and the response to antigen. Curr Opin Immunol 1999;11:265-269.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 265-269
-
-
Xavier, R.1
Seed, B.2
-
76
-
-
0034924486
-
The amplification of TCR signaling by dynamic membrane microdomains
-
Viola A. The amplification of TCR signaling by dynamic membrane microdomains. Trends Immunol 2001;22:322-327.
-
(2001)
Trends Immunol
, vol.22
, pp. 322-327
-
-
Viola, A.1
-
77
-
-
0034808099
-
Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes
-
Veri MC, DeBell KE, Seminario MC, DiBaldassarre A, Reischl I, Rawat R, Graham L, Noviello C, Rellahan BL, Miscia S, Wange RL, Bonvini E. Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes. Mol Cell Biol 2001;21:6939-6950.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6939-6950
-
-
Veri, M.C.1
DeBell, K.E.2
Seminario, M.C.3
Dibaldassarre, A.4
Reischl, I.5
Rawat, R.6
Graham, L.7
Noviello, C.8
Rellahan, B.L.9
Miscia, S.10
Wange, R.L.11
Bonvini, E.12
-
78
-
-
0034596827
-
Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling
-
Boerth NJ, Sadler JJ, Bauer DE, Clements JL, Gheith SM, Koretzky GA. Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling. J Exp Med 2000;192:1047-1058.
-
(2000)
J Exp Med
, vol.192
, pp. 1047-1058
-
-
Boerth, N.J.1
Sadler, J.J.2
Bauer, D.E.3
Clements, J.L.4
Gheith, S.M.5
Koretzky, G.A.6
-
79
-
-
0032212728
-
LAT is required for TCR-mediated activation of PLCγ1 and the Ras pathway
-
Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCγ1 and the Ras pathway. Immunity 1998;9:617-626.
-
(1998)
Immunity
, vol.9
, pp. 617-626
-
-
Finco, T.S.1
Kadlecek, T.2
Zhang, W.3
Samelson, L.E.4
Weiss, A.5
-
80
-
-
0035374476
-
Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation
-
Bi K, Tanaka Y, Coudronniere N, Sugie K, Hong S, van Stipdonk MJ, Altman A. Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation. Nat Immunol 2001;2:556-563.
-
(2001)
Nat Immunol
, vol.2
, pp. 556-563
-
-
Bi, K.1
Tanaka, Y.2
Coudronniere, N.3
Sugie, K.4
Hong, S.5
Van Stipdonk, M.J.6
Altman, A.7
-
81
-
-
1542399850
-
Lipid raft proteins have a random distribution during localized activation of the T-cell receptor
-
Glebov OO, Nichols BJ. Lipid raft proteins have a random distribution during localized activation of the T-cell receptor. Nat Cell Biol 2004;6:238-243.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 238-243
-
-
Glebov, O.O.1
Nichols, B.J.2
-
82
-
-
20444404267
-
Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells
-
Douglass AD, Vale RD. Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell 2005;121:937-950.
-
(2005)
Cell
, vol.121
, pp. 937-950
-
-
Douglass, A.D.1
Vale, R.D.2
|