메뉴 건너뛰기




Volumn 400, Issue 1, 2010, Pages 16-20

TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha

Author keywords

Akt; PDK 2; PKC alpha; TCR

Indexed keywords

PROTEIN KINASE B; PROTEIN KINASE C ALPHA; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE; SERINE;

EID: 79959879513     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.126     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning B.D., Cantley L.C. AKT/PKB signaling: navigating downstream. Cell 2007, 129:1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 2
    • 33744457653 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia
    • Martelli A.M., Nyakern M., Tabellini G., Bortul R., Tazzari P.L., Evangelisti C., Cocco L. Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. Leukemia 2006, 20:911-928.
    • (2006) Leukemia , vol.20 , pp. 911-928
    • Martelli, A.M.1    Nyakern, M.2    Tabellini, G.3    Bortul, R.4    Tazzari, P.L.5    Evangelisti, C.6    Cocco, L.7
  • 4
    • 23844462453 scopus 로고    scopus 로고
    • Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase
    • Webb L.M., Vigorito E., Wymann M.P., Hirsch E., Turner M. Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J. Immunol. 2005, 175:2783-2787.
    • (2005) J. Immunol. , vol.175 , pp. 2783-2787
    • Webb, L.M.1    Vigorito, E.2    Wymann, M.P.3    Hirsch, E.4    Turner, M.5
  • 6
    • 0034658320 scopus 로고    scopus 로고
    • Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo
    • Jones R.G., Parsons M., Bonnard M., Chan V.S., Yeh W.C., Woodgett J.R., Ohashi P.S. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. J. Exp. Med. 2000, 191:1721-1734.
    • (2000) J. Exp. Med. , vol.191 , pp. 1721-1734
    • Jones, R.G.1    Parsons, M.2    Bonnard, M.3    Chan, V.S.4    Yeh, W.C.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 13
    • 39449087305 scopus 로고    scopus 로고
    • Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns
    • Sebzda E., Zou Z., Lee J.S., Wang T., Kahn M.L. Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns. Nat. Immunol. 2008, 9:292-300.
    • (2008) Nat. Immunol. , vol.9 , pp. 292-300
    • Sebzda, E.1    Zou, Z.2    Lee, J.S.3    Wang, T.4    Kahn, M.L.5
  • 14
    • 41149113441 scopus 로고    scopus 로고
    • The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
    • Haxhinasto S., Mathis D., Benoist C. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J. Exp. Med. 2008, 205:565-574.
    • (2008) J. Exp. Med. , vol.205 , pp. 565-574
    • Haxhinasto, S.1    Mathis, D.2    Benoist, C.3
  • 16
    • 23044467856 scopus 로고    scopus 로고
    • PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle
    • Dong L.Q., Liu F. PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle. Am. J. Physiol. Endocrinol. Metab. 2005, 289:E187-E196.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289
    • Dong, L.Q.1    Liu, F.2
  • 17
    • 63749119765 scopus 로고    scopus 로고
    • PIKKing on PKB: regulation of PKB activity by phosphorylation
    • Bozulic L., Hemmings B.A. PIKKing on PKB: regulation of PKB activity by phosphorylation. Curr. Opin. Cell Biol. 2009, 21:256-261.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 256-261
    • Bozulic, L.1    Hemmings, B.A.2
  • 19
    • 0035936653 scopus 로고    scopus 로고
    • PDK2: a complex tail in one Akt
    • Chan T.O., Tsichlis P.N. PDK2: a complex tail in one Akt. Sci. STKE 2001, 2001:e1.
    • (2001) Sci. STKE , vol.2001
    • Chan, T.O.1    Tsichlis, P.N.2
  • 20
    • 0035920145 scopus 로고    scopus 로고
    • Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343
    • Persad S., Attwell S., Gray V., Mawji N., Deng J.T., Leung D., Yan J., Sanghera J., Walsh M.P., Dedhar S. Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343. J. Biol. Chem. 2001, 276:27462-27469.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27462-27469
    • Persad, S.1    Attwell, S.2    Gray, V.3    Mawji, N.4    Deng, J.T.5    Leung, D.6    Yan, J.7    Sanghera, J.8    Walsh, M.P.9    Dedhar, S.10
  • 21
    • 2442562698 scopus 로고    scopus 로고
    • Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase C alpha in endothelial cells
    • Partovian C., Simons M. Regulation of protein kinase B/Akt activity and Ser473 phosphorylation by protein kinase C alpha in endothelial cells. Cell Signal. 2004, 16:951-957.
    • (2004) Cell Signal. , vol.16 , pp. 951-957
    • Partovian, C.1    Simons, M.2
  • 23
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov D.D., Guertin D.A., Ali S.M., Sabatini D.M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 2005, 307:1098-1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 28
    • 41149145089 scopus 로고    scopus 로고
    • T cell receptor-induced NF-{kappa}B activation is negatively regulated by E3 ubiquitin ligase Cbl-b
    • Qiao G., Li Z., Molinero L., Alegre M.L., Ying H., Sun Z., Penninger J.M., Zhang J. T cell receptor-induced NF-{kappa}B activation is negatively regulated by E3 ubiquitin ligase Cbl-b. Mol. Cell Biol. 2008, 28:2470-2480.
    • (2008) Mol. Cell Biol. , vol.28 , pp. 2470-2480
    • Qiao, G.1    Li, Z.2    Molinero, L.3    Alegre, M.L.4    Ying, H.5    Sun, Z.6    Penninger, J.M.7    Zhang, J.8
  • 29
    • 0027418818 scopus 로고
    • Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
    • Baier G., Telford D., Giampa L., Coggeshall K.M., Baier-Bitterlich G., Isakov N., Altman A. Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. J. Biol. Chem. 1993, 268:4997-5004.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4997-5004
    • Baier, G.1    Telford, D.2    Giampa, L.3    Coggeshall, K.M.4    Baier-Bitterlich, G.5    Isakov, N.6    Altman, A.7
  • 30
    • 0037902559 scopus 로고    scopus 로고
    • Protein kinase C-theta (PKCtheta): it's all about location, location, location
    • Altman A., Villalba M. Protein kinase C-theta (PKCtheta): it's all about location, location, location. Immunol. Rev. 2003, 192:53-63.
    • (2003) Immunol. Rev. , vol.192 , pp. 53-63
    • Altman, A.1    Villalba, M.2
  • 34
    • 67649232595 scopus 로고    scopus 로고
    • Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta
    • Fehrenbach K., Lessmann E., Zorn C.N., Kuhny M., Grochowy G., Krystal G., Leitges M., Huber M. Steel factor enhances supraoptimal antigen-induced IL-6 production from mast cells via activation of protein kinase C-beta. J. Immunol. 2009, 182:7897-7905.
    • (2009) J. Immunol. , vol.182 , pp. 7897-7905
    • Fehrenbach, K.1    Lessmann, E.2    Zorn, C.N.3    Kuhny, M.4    Grochowy, G.5    Krystal, G.6    Leitges, M.7    Huber, M.8
  • 35
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes
    • Gschwendt M., Dieterich S., Rennecke J., Kittstein W., Mueller H.J., Johannes F.J. Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 1996, 392:77-80.
    • (1996) FEBS Lett. , vol.392 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.J.5    Johannes, F.J.6
  • 36
    • 15044363028 scopus 로고    scopus 로고
    • Recent advances in the protein kinase B signaling pathway
    • Woodgett J.R. Recent advances in the protein kinase B signaling pathway. Curr. Opin. Cell Biol. 2005, 17:150-157.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 150-157
    • Woodgett, J.R.1
  • 37
    • 0036333737 scopus 로고    scopus 로고
    • Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
    • Scheid M.P., Marignani P.A., Woodgett J.R. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell Biol. 2002, 22:6247-6260.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 6247-6260
    • Scheid, M.P.1    Marignani, P.A.2    Woodgett, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.