Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria

Acta Crystallographica Section D: Biological Crystallography

Volumn 68, Issue 10, 2012, Pages 1359-1370

  Halavaty, Andrei S ^a,b   Kim, Youngchang ^a,c,d   Minasov, George ^a,b   Shuvalova, Ludmilla ^a,b   Dubrovska, Ievgeniia ^a,b   Winsor, James ^a,b   Zhou, Min ^a,c,d   Onopriyenko, Olena ^a,e   Skarina, Tatiana ^a,e   Papazisi, Leka ^a,f   Kwon, Keehwan ^a,f   Peterson, Scott N ^a,f   Joachimiak, Andrzej ^a,c,d   Savchenko, Alexei ^a,e   Anderson, Wayne F ^a,b  

^a Center for Structural Genomics of Infectious Diseases   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f J CRAIG VENTER INSTITUTE   (United States)

Author keywords

3 ,5 adenosine diphosphate; acyl carrier protein; acyl carrier protein synthase; coenzyme A; inhibition; type II fatty acid synthesis

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; APOENZYME; BACTERIAL PROTEIN; HOLOENZYME;

ARTICLE; BACILLUS ANTHRACIS; CATALYSIS; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; ENZYMOLOGY; PATHOGENICITY; STAPHYLOCOCCUS AUREUS; VIBRIO CHOLERAE; X RAY CRYSTALLOGRAPHY;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; APOENZYMES; BACILLUS ANTHRACIS; BACTERIAL PROTEINS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HOLOENZYMES; STAPHYLOCOCCUS AUREUS; VIBRIO CHOLERAE;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS; VIBRIO CHOLERAE;

EID: 84866706479     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444912029101     Document Type: Article

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