10-Formyltetrahydrofolate dehydrogenase requires a 4′- phosphopantetheine prosthetic group for catalysis

Journal of Biological Chemistry

Volumn 282, Issue 47, 2007, Pages 34159-34166

  Donato, Henry ^a,b   Krupenko, Natalia I ^a   Tsybovsky, Yaroslav ^a   Krupenko, Sergey A ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b School of Business   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC MECHANISM; HYDROLYTIC CLEAVAGE; PHOSPHOPANTETHEINE SWINGING ARM; STRUCTURAL ORGANIZATION;

AMINO ACIDS; CATALYSIS; ENZYMES; OXIDATION;

CATALYST ACTIVITY;

ACYL CARRIER PROTEIN; ALDEHYDE DEHYDROGENASE; ALKALINE PHOSPHATASE; CARRIER PROTEIN; DIHYDROFOLATE REDUCTASE; FORMYLTETRAHYDROFOLATE DEHYDROGENASE; MALEIMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PANTETHEINE PHOSPHATE; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ESCHERICHIA COLI; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

ACYL CARRIER PROTEIN; ANIMALS; CARBON DIOXIDE; CATALYSIS; LEUCOVORIN; NADP; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PANTETHEINE; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; TETRAHYDROFOLATES;

RATTUS;

EID: 36048947884     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707627200     Document Type: Article

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