Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: An essential enzyme in bacterial fatty acid biosynthesis

EMBO Journal

Volumn 19, Issue 20, 2000, Pages 5281-5287

  Chirgadze, N Y ^a   Briggs, S L ^a   McAllister, K A ^a   Fischl, A S ^a   Zhao, G ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Acyl carrier protein synthase; Bacterial fatty acid biosynthesis; Coenzyme A; Structure based drug design; X ray crystallography

Indexed keywords

ACYL CARRIER PROTEIN; BACTERIAL ENZYME; ENZYME INHIBITOR; FATTY ACID; OLIGOMER; SYNTHETASE;

ARTICLE; BACTERIAL METABOLISM; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ACTIVE SITE; ENZYME STRUCTURE; FATTY ACID SYNTHESIS; GENETIC CONSERVATION; LIPOGENESIS; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; STREPTOCOCCUS PNEUMONIAE;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 0034675957     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.20.5281     Document Type: Article

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