X-ray structure of plasmepsin II complexed with a potent achiral inhibitor

Journal of Biological Chemistry

Volumn 280, Issue 25, 2005, Pages 23837-23843

  Prade, Lars ^a   Jones, Andrew F ^a   Boss, Christoph ^a   Richard Bildstein, Sylvia ^a   Meyer, Solange ^a   Binkert, Christoph ^a   Bur, Daniel ^a  

^a ACTELION PHARMACEUTICALS LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BLOOD; CELLS; COMPLEXATION; DISEASES; ENZYME INHIBITION; HEMOGLOBIN; X RAY ANALYSIS;

ACHIRAL INHIBITORS; MALARIA PARASITE; PLASMEPSINS (PM);

ENZYMES;

ENZYME INHIBITOR; PLASMEPSIN II;

ARTICLE; COMPLEX FORMATION; DRUG BINDING SITE; ENZYME ACTIVE SITE; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; SYNTHESIS; X RAY ANALYSIS;

ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 21244486379     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501519200     Document Type: Article

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