메뉴 건너뛰기




Volumn 19, Issue 9, 2012, Pages 1126-1141

Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; TRANSCRIPTOME;

EID: 84866705943     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.07.020     Document Type: Article
Times cited : (25)

References (74)
  • 1
    • 0031021312 scopus 로고    scopus 로고
    • Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer
    • DOI 10.1021/bi961125c
    • V.E. Allgood, Y. Zhang, B.W. O'Malley, and N.L. Weigel Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer Biochemistry 36 1997 224 232 (Pubitemid 27024696)
    • (1997) Biochemistry , vol.36 , Issue.1 , pp. 224-232
    • Allgood, V.E.1    Zhang, Y.2    O'Malley, B.W.3    Weigel, N.L.4
  • 3
    • 79953673206 scopus 로고    scopus 로고
    • High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes
    • F.J. Ashcroft, J.Y. Newberg, E.D. Jones, I. Mikic, and M.A. Mancini High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes Gene 477 2011 42 52
    • (2011) Gene , vol.477 , pp. 42-52
    • Ashcroft, F.J.1    Newberg, J.Y.2    Jones, E.D.3    Mikic, I.4    Mancini, M.A.5
  • 7
    • 34547931715 scopus 로고    scopus 로고
    • Cell- and gene-specific regulation of primary target genes by the androgen receptor
    • DOI 10.1101/gad.1564207
    • E.C. Bolton, A.Y. So, C. Chaivorapol, C.M. Haqq, H. Li, and K.R. Yamamoto Cell- and gene-specific regulation of primary target genes by the androgen receptor Genes Dev. 21 2007 2005 2017 (Pubitemid 47267287)
    • (2007) Genes and Development , vol.21 , Issue.16 , pp. 2005-2017
    • Bolton, E.C.1    So, A.Y.2    Chaivorapol, C.3    Haqq, C.M.4    Li, H.5    Yamamoto, K.R.6
  • 8
    • 33750380754 scopus 로고    scopus 로고
    • Expression profiling of 11β-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subscutaneous and omental human preadipocytes
    • DOI 10.1677/jme.1.02048
    • I.J. Bujalska, M. Quinkler, J.W. Tomlinson, C.T. Montague, D.M. Smith, and P.M. Stewart Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes J. Mol. Endocrinol. 37 2006 327 340 (Pubitemid 44615302)
    • (2006) Journal of Molecular Endocrinology , vol.37 , Issue.2 , pp. 327-340
    • Bujalska, I.J.1    Quinkler, M.2    Tomlinson, J.W.3    Montague, C.T.4    Smith, D.M.5    Stewart, P.M.6
  • 9
    • 0029623091 scopus 로고
    • Androgen and glucocorticoid regulation of androgen receptor cDNA expression
    • DOI 10.1016/0303-7207(95)03688-1
    • K.L. Burnstein, C.A. Maiorino, J.L. Dai, and D.J. Cameron Androgen and glucocorticoid regulation of androgen receptor cDNA expression Mol. Cell Endocrinol. 115 1995 177 186 (Pubitemid 26010863)
    • (1995) Molecular and Cellular Endocrinology , vol.115 , Issue.2 , pp. 177-186
    • Burnstein, K.L.1    Maiorino, C.A.2    Dai, J.L.3    Cameron, D.J.4
  • 11
    • 0023929785 scopus 로고
    • Molecular cloning of human and rat complementary DNA encoding androgen receptors
    • C.S. Chang, J. Kokontis, and S.T. Liao Molecular cloning of human and rat complementary DNA encoding androgen receptors Science 240 1988 324 326
    • (1988) Science , vol.240 , pp. 324-326
    • Chang, C.S.1    Kokontis, J.2    Liao, S.T.3
  • 12
    • 0030958355 scopus 로고    scopus 로고
    • Androgen and glucocorticoid receptor heterodimer formation: A possible mechanism for mutual inhibition of transcriptional activity
    • DOI 10.1074/jbc.272.22.14087
    • S.Y. Chen, J. Wang, G.Q. Yu, W.H. Liu, and D. Pearce Androgen and glucocorticoid receptor heterodimer formation - A possible mechanism for mutual inhibition of transcriptional activity J. Biol. Chem. 272 1997 14087 14092 (Pubitemid 27232812)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.22 , pp. 14087-14092
    • Chen, S.-Y.1    Wang, J.2    Yu, G.-Q.3    Liu, W.4    Pearce, D.5
  • 13
    • 34249753618 scopus 로고
    • Support vector networks
    • C. Cortes, and V. Vapnik Support vector networks Mach. Learn. 20 1995 273 297
    • (1995) Mach. Learn. , vol.20 , pp. 273-297
    • Cortes, C.1    Vapnik, V.2
  • 14
    • 32544457993 scopus 로고    scopus 로고
    • Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance
    • DOI 10.1210/jc.2005-1666
    • A.D. Coviello, R.S. Legro, and A. Dunaif Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance J. Clin. Endocrinol. Metab. 91 2006 492 497 (Pubitemid 43236914)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.2 , pp. 492-497
    • Coviello, A.D.1    Legro, R.S.2    Dunaif, A.3
  • 16
    • 0025110831 scopus 로고
    • Association of glucocorticoid receptors with prostate nuclear sites for androgen receptors and with androgen response elements
    • P. Davies, and N.K. Rushmere Association of glucocorticoid receptors with prostate nuclear sites for androgen receptors and with androgen response elements J. Mol. Endocrinol. 5 1990 117 127 (Pubitemid 20314403)
    • (1990) Journal of Molecular Endocrinology , vol.5 , Issue.2 , pp. 117-127
    • Davies, P.1    Rushmere, N.K.2
  • 18
    • 26844569694 scopus 로고    scopus 로고
    • PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs
    • DOI 10.1002/jemt.20215
    • J.N. Feige, D. Sage, W. Wahli, B. Desvergne, and L. Gelman PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs Microsc. Res. Tech. 68 2005 51 58 (Pubitemid 41464009)
    • (2005) Microscopy Research and Technique , vol.68 , Issue.1 , pp. 51-58
    • Feige, J.N.1    Sage, D.2    Wahli, W.3    Desvergne, B.4    Gelman, L.5
  • 22
    • 33847041824 scopus 로고    scopus 로고
    • Hypoandrogen-metabolic syndrome: A potentially common and underdiagnosed condition in men
    • D.C. Gould, R.S. Kirby, and P. Amoroso Hypoandrogen-metabolic syndrome: a potentially common and underdiagnosed condition in men Int. J. Clin. Pract. 61 2007 341 344
    • (2007) Int. J. Clin. Pract. , vol.61 , pp. 341-344
    • Gould, D.C.1    Kirby, R.S.2    Amoroso, P.3
  • 23
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • DOI 10.1038/nrm2391, PII NRM2391
    • A. Guilherme, J.V. Virbasius, V. Puri, and M.P. Czech Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes Nat. Rev. Mol. Cell Biol. 9 2008 367 377 (Pubitemid 351574198)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.5 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 25
    • 78651329138 scopus 로고    scopus 로고
    • Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis
    • S.M. Hartig, B. He, W. Long, B.M. Buehrer, and M.A. Mancini Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis J. Cell Biol. 192 2011 55 72
    • (2011) J. Cell Biol. , vol.192 , pp. 55-72
    • Hartig, S.M.1    He, B.2    Long, W.3    Buehrer, B.M.4    Mancini, M.A.5
  • 26
    • 0029847504 scopus 로고    scopus 로고
    • Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein
    • DOI 10.1126/science.274.5291.1377
    • G.S. Hotamisligil, R.S. Johnson, R.J. Distel, R. Ellis, V.E. Papaioannou, and B.M. Spiegelman Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein Science 274 1996 1377 1379 (Pubitemid 26391462)
    • (1996) Science , vol.274 , Issue.5291 , pp. 1377-1379
    • Hotamisligil, G.S.1    Johnson, R.S.2    Distel, R.J.3    Ellis, R.4    Papaioannou, V.E.5    Spiegelman, B.M.6
  • 27
    • 0002997383 scopus 로고
    • Stepwise discriminant analysis
    • K. Enslein, A. Ralston, H.S. Wilf, John Wiley & Sons New York, NY
    • R.I. Jennrich Stepwise discriminant analysis K. Enslein, A. Ralston, H.S. Wilf, Statistical methods for digital computers 1977 John Wiley & Sons New York, NY 77 95
    • (1977) Statistical Methods for Digital Computers , pp. 77-95
    • Jennrich, R.I.1
  • 28
    • 65249138882 scopus 로고    scopus 로고
    • AR inhibitors identified by high-throughput microscopy detection of conformational change and subcellular localization
    • J.O. Jones, W.F. An, and M.I. Diamond AR inhibitors identified by high-throughput microscopy detection of conformational change and subcellular localization ACS Chem. Biol. 4 2009 199 208
    • (2009) ACS Chem. Biol. , vol.4 , pp. 199-208
    • Jones, J.O.1    An, W.F.2    Diamond, M.I.3
  • 29
    • 0032935119 scopus 로고    scopus 로고
    • Distinguishing androgen receptor agonists and antagonists: Distinct mechanisms of activation by medroxyprogesterone acetate and dihydrotestosterone
    • J.A. Kemppainen, E. Langley, C.I. Wong, K. Bobseine, W.R. Kelce, and E.M. Wilson Distinguishing androgen receptor agonists and antagonists: distinct mechanisms of activation by medroxyprogesterone acetate and dihydrotestosterone Mol. Endocrinol. 13 1999 440 454 (Pubitemid 29113876)
    • (1999) Molecular Endocrinology , vol.13 , Issue.3 , pp. 440-454
    • Kemppainen, J.A.1    Langley, E.2    Wong, C.-I.3    Bobseine, K.4    Kelce, W.R.5    Wilson, E.M.6
  • 31
    • 77958571302 scopus 로고    scopus 로고
    • Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis
    • M. Lahnalampi, M. Heinäniemi, L. Sinkkonen, M. Wabitsch, and C. Carlberg Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis PLoS ONE 5 2010 e12991
    • (2010) PLoS ONE , vol.5 , pp. 12991
    • Lahnalampi, M.1    Heinäniemi, M.2    Sinkkonen, L.3    Wabitsch, M.4    Carlberg, C.5
  • 32
    • 0029560494 scopus 로고
    • Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer
    • DOI 10.1074/jbc.270.50.29983
    • E. Langley, Z.X. Zhou, and E.M. Wilson Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer J. Biol. Chem. 270 1995 29983 29990 (Pubitemid 26001674)
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.50 , pp. 29983-29990
    • Langley, E.1    Zhou, Z.-X.2    Wilson, E.M.3
  • 33
    • 44449135106 scopus 로고    scopus 로고
    • Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue
    • DOI 10.1038/oby.2008.207, PII OBY2008207
    • M.J. Lee, S.K. Fried, S.S. Mundt, Y. Wang, S. Sullivan, A. Stefanni, B.L. Daugherty, and A. Hermanowski-Vosatka Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue Obesity (Silver Spring) 16 2008 1178 1185 (Pubitemid 351770504)
    • (2008) Obesity , vol.16 , Issue.6 , pp. 1178-1185
    • Lee, M.-J.1    Fried, S.K.2    Mundt, S.S.3    Wang, Y.4    Sullivan, S.5    Stefanni, A.6    Daugherty, B.L.7    Hermanowski-Vosatka, A.8
  • 35
    • 7244232742 scopus 로고    scopus 로고
    • Regulating the balance between peroxisome proliferator-activated receptor γ and β-catenin signaling during adipogenesis: A glycogen synthase kinase 3β phosphorylation-defective mutant of β-catenin inhibits expression of a subset of adipogenic genes
    • DOI 10.1074/jbc.M407050200
    • J. Liu, and S.R. Farmer Regulating the balance between peroxisome proliferator-activated receptor gamma and beta-catenin signaling during adipogenesis. A glycogen synthase kinase 3beta phosphorylation-defective mutant of beta-catenin inhibits expression of a subset of adipogenic genes J. Biol. Chem. 279 2004 45020 45027 (Pubitemid 39430916)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.43 , pp. 45020-45027
    • Liu, J.1    Farmer, S.R.2
  • 36
    • 77955286961 scopus 로고    scopus 로고
    • Androgen excess produces systemic oxidative stress and predisposes to beta-cell failure in female mice
    • S. Liu, G. Navarro, and F. Mauvais-Jarvis Androgen excess produces systemic oxidative stress and predisposes to beta-cell failure in female mice PLoS ONE 5 2010 e11302
    • (2010) PLoS ONE , vol.5 , pp. 11302
    • Liu, S.1    Navarro, G.2    Mauvais-Jarvis, F.3
  • 37
    • 0027193909 scopus 로고
    • Characterization of the interaction of the human mineralocorticosteroid receptor with hormone response elements
    • M. Lombès, N. Binart, M.E. Oblin, V. Joulin, and E.E. Baulieu Characterization of the interaction of the human mineralocorticosteroid receptor with hormone response elements Biochem. J. 292 1993 577 583 (Pubitemid 23181977)
    • (1993) Biochemical Journal , vol.292 , Issue.2 , pp. 577-583
    • Lombes, M.1    Binart, N.2    Oblin, M.-E.3    Joulin, V.4    Baulieu, E.E.5
  • 38
    • 0023910355 scopus 로고
    • Cloning of human androgen receptor complementary DNA and localization to the X chromosome
    • D.B. Lubahn, D.R. Joseph, P.M. Sullivan, H.F. Willard, F.S. French, and E.M. Wilson Cloning of human androgen receptor complementary DNA and localization to the X chromosome Science 240 1988 327 330
    • (1988) Science , vol.240 , pp. 327-330
    • Lubahn, D.B.1    Joseph, D.R.2    Sullivan, P.M.3    Willard, H.F.4    French, F.S.5    Wilson, E.M.6
  • 40
    • 29344467436 scopus 로고    scopus 로고
    • Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element
    • DOI 10.1210/en.2005-1001
    • J.A. Magee, L.W. Chang, G.D. Stormo, and J. Milbrandt Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element Endocrinology 147 2006 590 598 (Pubitemid 43004313)
    • (2006) Endocrinology , vol.147 , Issue.1 , pp. 590-598
    • Magee, J.A.1    Chang, L.-W.2    Stormo, G.D.3    Milbrandt, J.4
  • 42
    • 0035824440 scopus 로고    scopus 로고
    • A transgenic model of visceral obesity and the metabolic syndrome
    • DOI 10.1126/science.1066285
    • H. Masuzaki, J. Paterson, H. Shinyama, N.M. Morton, J.J. Mullins, J.R. Seckl, and J.S. Flier A transgenic model of visceral obesity and the metabolic syndrome Science 294 2001 2166 2170 (Pubitemid 33150673)
    • (2001) Science , vol.294 , Issue.5549 , pp. 2166-2170
    • Masuzaki, H.1    Paterson, J.2    Shinyama, H.3    Morton, N.M.4    Mullins, J.J.5    Seckl, J.R.6    Flier, J.S.7
  • 45
    • 78149406948 scopus 로고    scopus 로고
    • The PPAR gamma ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells
    • P.E. Moss, B.E. Lyles, and L.V. Stewart The PPAR gamma ligand ciglitazone regulates androgen receptor activation differently in androgen-dependent versus androgen-independent human prostate cancer cells Exp. Cell Res. 316 2010 3478 3488
    • (2010) Exp. Cell Res. , vol.316 , pp. 3478-3488
    • Moss, P.E.1    Lyles, B.E.2    Stewart, L.V.3
  • 46
    • 0033323810 scopus 로고    scopus 로고
    • A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1)
    • L.V. Nazareth, D.L. Stenoien, W.E. Bingman 3rd, A.J. James, C. Wu, Y. Zhang, D.P. Edwards, M. Mancini, M. Marcelli, D.J. Lamb, and N.L. Weigel A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) Mol. Endocrinol. 13 1999 2065 2075 (Pubitemid 30637267)
    • (1999) Molecular Endocrinology , vol.13 , Issue.12 , pp. 2065-2075
    • Nazareth, L.V.1    Stenoien, D.L.2    Bingman III, W.E.3    James, A.J.4    Wu, C.5    Zhang, Y.6    Edwards, D.P.7    Mancini, M.8    Marcelli, M.9    Lamb, D.J.10    Weigel, N.L.11
  • 48
    • 0025616221 scopus 로고
    • Structural determinants of a glucocorticoid receptor recognition element
    • S.K. Nordeen, B.J. Suh, B. Kühnel, and C.A. Hutchison 3rd Structural determinants of a glucocorticoid receptor recognition element Mol. Endocrinol. 4 1990 1866 1873
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1866-1873
    • Nordeen, S.K.1    Suh, B.J.2    Kühnel, B.3    Hutchison III, C.A.4
  • 49
    • 57349194332 scopus 로고    scopus 로고
    • Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro
    • C. Pantoja, J.T. Huff, and K.R. Yamamoto Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro Mol. Biol. Cell 19 2008 4032 4041
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4032-4041
    • Pantoja, C.1    Huff, J.T.2    Yamamoto, K.R.3
  • 51
  • 52
    • 0027056581 scopus 로고
    • A consensus DNA-binding site for the androgen receptor
    • DOI 10.1210/me.6.12.2229
    • P.J. Roche, S.A. Hoare, and M.G. Parker A consensus DNA-binding site for the androgen receptor Mol. Endocrinol. 6 1992 2229 2235 (Pubitemid 23021573)
    • (1992) Molecular Endocrinology , vol.6 , Issue.12 , pp. 2229-2235
    • Roche, P.J.1    Hoare, S.A.2    Parker, M.G.3
  • 56
    • 0034697122 scopus 로고    scopus 로고
    • Differences in DNA binding characteristics of the androgen and glucocorticoid receptors can determine hormone-specific responses
    • DOI 10.1074/jbc.275.16.12290
    • E. Schoenmakers, G. Verrijdt, B. Peeters, G. Verhoeven, W. Rombauts, and F. Claessens Differences in DNA binding characteristics of the androgen and glucocorticoid receptors can determine hormone-specific responses J. Biol. Chem. 275 2000 12290 12297 (Pubitemid 30237810)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.16 , pp. 12290-12297
    • Schoenmakers, E.1    Verrijdt, G.2    Peeters, B.3    Verhoeven, G.4    Rombauts, W.5    Claessens, F.6
  • 58
    • 0242468434 scopus 로고    scopus 로고
    • Androgens Stimulate Myogenic Differentiation and Inhibit Adipogenesis in C3H 10T1/2 Pluripotent Cells through an Androgen Receptor-Mediated Pathway
    • DOI 10.1210/en.2003-0741
    • R. Singh, J.N. Artaza, W.E. Taylor, N.F. Gonzalez-Cadavid, and S. Bhasin Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway Endocrinology 144 2003 5081 5088 (Pubitemid 37378423)
    • (2003) Endocrinology , vol.144 , Issue.11 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 59
    • 29344440814 scopus 로고    scopus 로고
    • Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with β-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors
    • DOI 10.1210/en.2004-1649
    • R. Singh, J.N. Artaza, W.E. Taylor, M. Braga, X. Yuan, N.F. Gonzalez-Cadavid, and S. Bhasin Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors Endocrinology 147 2006 141 154 (Pubitemid 43004269)
    • (2006) Endocrinology , vol.147 , Issue.1 , pp. 141-154
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Braga, M.4    Yuan, X.5    Gonzalez-Cadavid, N.F.6    Bhasin, S.7
  • 60
    • 79953756730 scopus 로고    scopus 로고
    • Species-specific strategies underlying conserved functions of metabolic transcription factors
    • R.E. Soccio, G. Tuteja, L.J. Everett, Z. Li, M.A. Lazar, and K.H. Kaestner Species-specific strategies underlying conserved functions of metabolic transcription factors Mol. Endocrinol. 25 2011 694 706
    • (2011) Mol. Endocrinol. , vol.25 , pp. 694-706
    • Soccio, R.E.1    Tuteja, G.2    Everett, L.J.3    Li, Z.4    Lazar, M.A.5    Kaestner, K.H.6
  • 61
    • 59849096860 scopus 로고    scopus 로고
    • Testosterone in obesity, metabolic syndrome and Type 2 diabetes
    • T.H. Jones, Karger Basel, Switzerland
    • R.D. Stanworth, and T.H. Jones Testosterone in obesity, metabolic syndrome and Type 2 diabetes T.H. Jones, Advances in the Management of Testosterone Deficiency Vol. 37 2009 Karger Basel, Switzerland 74 90
    • (2009) Advances in the Management of Testosterone Deficiency , vol.37 , pp. 74-90
    • Stanworth, R.D.1    Jones, T.H.2
  • 63
    • 56249084597 scopus 로고    scopus 로고
    • Androgen receptor functional analyses by high throughput imaging: Determination of ligand, cell cycle, and mutation-specific effects
    • A.T. Szafran, M. Szwarc, M. Marcelli, and M.A. Mancini Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects PLoS ONE 3 2008 e3605
    • (2008) PLoS ONE , vol.3 , pp. 3605
    • Szafran, A.T.1    Szwarc, M.2    Marcelli, M.3    Mancini, M.A.4
  • 64
    • 0026742650 scopus 로고
    • Effects of testosterone supplementation in the aging male
    • J.S. Tenover Effects of testosterone supplementation in the aging male J. Clin. Endocrinol. Metab. 75 1992 1092 1098
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 1092-1098
    • Tenover, J.S.1
  • 65
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
    • P. Tontonoz, E. Hu, and B.M. Spiegelman Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor Cell 79 1994 1147 1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 68
    • 34247626853 scopus 로고    scopus 로고
    • The Small Molecule Harmine Is an Antidiabetic Cell-Type-Specific Regulator of PPARγ Expression
    • DOI 10.1016/j.cmet.2007.03.010, PII S1550413107000733
    • H. Waki, K.W. Park, N. Mitro, L. Pei, R. Damoiseaux, D.C. Wilpitz, K. Reue, E. Saez, and P. Tontonoz The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression Cell Metab. 5 2007 357 370 (Pubitemid 46667757)
    • (2007) Cell Metabolism , vol.5 , Issue.5 , pp. 357-370
    • Waki, H.1    Park, K.W.2    Mitro, N.3    Pei, L.4    Damoiseaux, R.5    Wilpitz, D.C.6    Reue, K.7    Saez, E.8    Tontonoz, P.9
  • 69
    • 0035900780 scopus 로고    scopus 로고
    • Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids
    • A.D. Wallace, and J.A. Cidlowski Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids J. Biol. Chem. 276 2001 42714 42721
    • (2001) J. Biol. Chem. , vol.276 , pp. 42714-42721
    • Wallace, A.D.1    Cidlowski, J.A.2
  • 70
    • 0017089430 scopus 로고
    • Binding properties of androgen receptors. Evidence for identical receptors in rat testis, epididymis, and prostate
    • E.M. Wilson, and F.S. French Binding properties of androgen receptors. Evidence for identical receptors in rat testis, epididymis, and prostate J. Biol. Chem. 251 1976 5620 5629
    • (1976) J. Biol. Chem. , vol.251 , pp. 5620-5629
    • Wilson, E.M.1    French, F.S.2
  • 71
    • 33645803202 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells
    • C.C. Yang, C.Y. Ku, S. Wei, C.W. Shiau, C.S. Chen, J.J. Pinzone, and M.D. Ringel Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells Mol. Pharmacol. 69 2006 1564 1570
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1564-1570
    • Yang, C.C.1    Ku, C.Y.2    Wei, S.3    Shiau, C.W.4    Chen, C.S.5    Pinzone, J.J.6    Ringel, M.D.7
  • 72
    • 0031035857 scopus 로고    scopus 로고
    • Mutant and wild-type androgen receptors exhibit cross-talk on androgen- , glucocorticoid-, and progesterone-mediated transcription
    • DOI 10.1210/me.11.2.162
    • P.M. Yen, Y. Liu, J.J. Palvimo, M. Trifiro, J. Whang, L. Pinsky, O.A. Janne, and W.W. Chin Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription Mol. Endocrinol. 11 1997 162 171 (Pubitemid 27057429)
    • (1997) Molecular Endocrinology , vol.11 , Issue.2 , pp. 162-171
    • Yen, P.M.1    Liu, Y.2    Palvimo, J.J.3    Trifiro, M.4    Whang, J.5    Pinsky, L.6    Janne, O.A.7    Chin, W.W.8
  • 73
    • 78650882261 scopus 로고    scopus 로고
    • Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis
    • C.Y. Yu, O. Mayba, J.V. Lee, J. Tran, C. Harris, T.P. Speed, and J.C. Wang Genome-wide analysis of glucocorticoid receptor binding regions in adipocytes reveal gene network involved in triglyceride homeostasis PLoS ONE 5 2010 e15188
    • (2010) PLoS ONE , vol.5 , pp. 15188
    • Yu, C.Y.1    Mayba, O.2    Lee, J.V.3    Tran, J.4    Harris, C.5    Speed, T.P.6    Wang, J.C.7
  • 74
    • 70849117428 scopus 로고    scopus 로고
    • Testosterone deficiency, insulin resistance and the metabolic syndrome
    • M. Zitzmann Testosterone deficiency, insulin resistance and the metabolic syndrome Nat. Rev. Endocrinol. 5 2009 673 681
    • (2009) Nat. Rev. Endocrinol. , vol.5 , pp. 673-681
    • Zitzmann, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.