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Volumn 147, Issue 1, 2006, Pages 141-154

Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: Nuclear translocation of androgen receptor complex with β-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; BETA CATENIN; BICALUTAMIDE; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN DELTA; COMPLEMENTARY DNA; ETOPOSIDE; FLUTAMIDE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2; T CELL FACTOR PROTEIN; T CELL GROWTH FACTOR 4; TESTOSTERONE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WNT1 PROTEIN;

EID: 29344440814     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2004-1649     Document Type: Article
Times cited : (325)

References (52)
  • 3
    • 0024003959 scopus 로고
    • Androgen abuse by athletes
    • Wilson JD 1988 Androgen abuse by athletes. Endocr Rev 9:181-191
    • (1988) Endocr Rev , vol.9 , pp. 181-191
    • Wilson, J.D.1
  • 10
    • 0032926459 scopus 로고    scopus 로고
    • Modulation of rat preadipocyte adipose conversion by androgenic status: Involvement of C/EBPs transcription factors
    • Garcia E, Lacasa M, Agli B, Giudicelli Y, Lacasa D 1999 Modulation of rat preadipocyte adipose conversion by androgenic status: involvement of C/EBPs transcription factors. J Endocrinol 161:89-97
    • (1999) J Endocrinol , vol.161 , pp. 89-97
    • Garcia, E.1    Lacasa, M.2    Agli, B.3    Giudicelli, Y.4    Lacasa, D.5
  • 11
    • 0034465232 scopus 로고    scopus 로고
    • Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: Evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor-γ2
    • Dieudonne MN, Pecquery R, Leneveu MC, Giudicelli Y 2000 Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor-γ2. Endocrinology 141:649-656
    • (2000) Endocrinology , vol.141 , pp. 649-656
    • Dieudonne, M.N.1    Pecquery, R.2    Leneveu, M.C.3    Giudicelli, Y.4
  • 12
    • 0031048003 scopus 로고    scopus 로고
    • Evidence for sex steroid inhibition of lipoprotein lipase in men: Comparison of abdominal and femoral adipose tissue
    • Ramirez ME, McMurry MP, Wiebke GA, Felten KJ, Ren K, Meikle AW, Iverius PH 1997 Evidence for sex steroid inhibition of lipoprotein lipase in men: comparison of abdominal and femoral adipose tissue. Metabolism 46:179-185
    • (1997) Metabolism , vol.46 , pp. 179-185
    • Ramirez, M.E.1    McMurry, M.P.2    Wiebke, G.A.3    Felten, K.J.4    Ren, K.5    Meikle, A.W.6    Iverius, P.H.7
  • 13
    • 0029819286 scopus 로고    scopus 로고
    • Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men: A clinical research center study
    • Brodsky IG, Balagopal P, Nair KS 1996 Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men: a clinical research center study. J Clin Endocrinol Metab 81:3469-3475
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3469-3475
    • Brodsky, I.G.1    Balagopal, P.2    Nair, K.S.3
  • 15
    • 0028797188 scopus 로고
    • Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: Effects of androgens
    • Marin P, Oden B, Bjorntorp P 1995 Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens. J Clin Endocrinol Metab 80:239-243
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 239-243
    • Marin, P.1    Oden, B.2    Bjorntorp, P.3
  • 16
    • 0026929033 scopus 로고
    • Androgen treatment of middle-aged, obese men: Effects on metabolism, muscle and adipose tissues
    • Marin P, Krotkiewski M, Bjorntorp P 1992 Androgen treatment of middle-aged, obese men: effects on metabolism, muscle and adipose tissues. Eur J Med 1:329-336
    • (1992) Eur J Med , vol.1 , pp. 329-336
    • Marin, P.1    Krotkiewski, M.2    Bjorntorp, P.3
  • 17
    • 0031798630 scopus 로고    scopus 로고
    • Androgen receptors in human preadipocytes and adipocytes: Regional specificities and regulation by sex steroids
    • Dieudonne MN, Pecquery R, Boumediene A, Lenevew MC, Giudicelli Y 1998 Androgen receptors in human preadipocytes and adipocytes: regional specificities and regulation by sex steroids. Am J Physiol 274:C1645-C1652
    • (1998) Am J Physiol , vol.274
    • Dieudonne, M.N.1    Pecquery, R.2    Boumediene, A.3    Lenevew, M.C.4    Giudicelli, Y.5
  • 18
    • 0027146249 scopus 로고
    • Androgen receptors in hamster white adipocytes and their precursor cells: Regional variations and modulation by androgens
    • Jaubert AM, Pecquery R, Sichez L, Dieudonne MN, Cloix JF, Giudicelli Y 1993 Androgen receptors in hamster white adipocytes and their precursor cells: regional variations and modulation by androgens. Endocrine 1:535-540
    • (1993) Endocrine , vol.1 , pp. 535-540
    • Jaubert, A.M.1    Pecquery, R.2    Sichez, L.3    Dieudonne, M.N.4    Cloix, J.F.5    Giudicelli, Y.6
  • 21
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • Singh R, Artaza JN, Taylor WE, Gonzalez-Cadavid NF, Bhasin S 2003 Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology 44:5081-5088
    • (2003) Endocrinology , vol.44 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 23
    • 0037124062 scopus 로고    scopus 로고
    • The androgen receptor can promote β-catenin nuclear translocation independently of adenomatous polyposis coli
    • Mulholland DJ, Cheng H, Reid K, Rennie PS, Nelson CC 2002 The androgen receptor can promote β-catenin nuclear translocation independently of adenomatous polyposis coli. J Biol Chem 277:17933-17943
    • (2002) J Biol Chem , vol.277 , pp. 17933-17943
    • Mulholland, D.J.1    Cheng, H.2    Reid, K.3    Rennie, P.S.4    Nelson, C.C.5
  • 24
    • 0037036393 scopus 로고    scopus 로고
    • Liganded androgen receptor interaction with β-catenin: Nuclear co-localization and modulation of transcriptional activity in neuronal cells
    • Pawlowski JE, Ertel JR, Allen MP, Xu M, Butler C, Wilson EM, Wierman ME 2002 Liganded androgen receptor interaction with β-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem 277:20702-20710
    • (2002) J Biol Chem , vol.277 , pp. 20702-20710
    • Pawlowski, J.E.1    Ertel, J.R.2    Allen, M.P.3    Xu, M.4    Butler, C.5    Wilson, E.M.6    Wierman, M.E.7
  • 26
    • 0034283030 scopus 로고    scopus 로고
    • β-Catenin affects androgen receptor transcriptional activity and ligand specificity
    • Truica CI, Byers S, Gelmann EP 2000 β-Catenin affects androgen receptor transcriptional activity and ligand specificity. Cancer Res 60:4709-4713
    • (2000) Cancer Res , vol.60 , pp. 4709-4713
    • Truica, C.I.1    Byers, S.2    Gelmann, E.P.3
  • 27
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM, Nusse R 1997 Wnt signaling: a common theme in animal development. Genes Dev 11:3286-3305
    • (1997) Genes Dev , vol.11 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 28
    • 0033572923 scopus 로고    scopus 로고
    • Wnt signaling and the activation of myogenesis in mammals
    • Cossu G, Borello U 1999 Wnt signaling and the activation of myogenesis in mammals. EMBO J 24:6867-6872
    • (1999) EMBO J , vol.24 , pp. 6867-6872
    • Cossu, G.1    Borello, U.2
  • 29
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, β-catenin, and cadherin pathways
    • Nelson WJ, Nusse R 2004 Convergence of Wnt, β-catenin, and cadherin pathways. Science 303:1483-1487
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 30
    • 0037387386 scopus 로고    scopus 로고
    • Wnt-frizzled signaling in the induction and differentiation of the neural crest
    • Yanfeng W, Saint-Jeannet JP, Klein PS 2003 Wnt-frizzled signaling in the induction and differentiation of the neural crest. Bioessays 25:317-325
    • (2003) Bioessays , vol.25 , pp. 317-325
    • Yanfeng, W.1    Saint-Jeannet, J.P.2    Klein, P.S.3
  • 31
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano Y, Kypta R 2003 Secreted antagonists of the Wnt signalling pathway. J Cell Sci 116:2627-2634
    • (2003) J Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 32
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P 2000 Wnt signaling and cancer. Genes Dev 14:1837-1851
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 33
    • 0033486152 scopus 로고    scopus 로고
    • β-Catenin signaling and cancer
    • Morin PJ 1999 β-Catenin signaling and cancer. Bioessays 21:1021-1030
    • (1999) Bioessays , vol.21 , pp. 1021-1030
    • Morin, P.J.1
  • 37
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire FM, Smas CA, Sul HS 1998 Understanding adipocyte differentiation. Physiol Rev 78:783-808
    • (1998) Physiol Rev , vol.78 , pp. 783-808
    • Gregoire, F.M.1    Smas, C.A.2    Sul, H.S.3
  • 39
    • 0017239088 scopus 로고
    • Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells
    • Green H, Kehinde O 1976 Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 1:105-113
    • (1976) Cell , vol.1 , pp. 105-113
    • Green, H.1    Kehinde, O.2
  • 40
    • 0032913866 scopus 로고    scopus 로고
    • Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter
    • Lu S, Liu M, Epner DE, Tsai SY, Tsai MJ 1999 Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol 13:376-384
    • (1999) Mol Endocrinol , vol.13 , pp. 376-384
    • Lu, S.1    Liu, M.2    Epner, D.E.3    Tsai, S.Y.4    Tsai, M.J.5
  • 41
    • 0030881804 scopus 로고    scopus 로고
    • Signaling pathways through which insulin regulates CCAAT/enhancer binding protein-α (C/EBP-α) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression
    • Hemati N, Ross SE, Erickson RL, Groblewski GE, MacDougald OA 1997 Signaling pathways through which insulin regulates CCAAT/enhancer binding protein-α (C/EBP-α) phosphorylation and gene expression in 3T3-L1 adipocytes. Correlation with GLUT4 gene expression. J Biol Chem 272:25913-25919
    • (1997) J Biol Chem , vol.272 , pp. 25913-25919
    • Hemati, N.1    Ross, S.E.2    Erickson, R.L.3    Groblewski, G.E.4    MacDougald, O.A.5
  • 42
    • 0036134990 scopus 로고    scopus 로고
    • Endogenous expression and localization of myostatin and its relation to myosin heavy chain distribution in C2C12 skeletal muscle cells
    • Artaza JN, Bhasin, S, Mallidis C, Taylor W, Ma K, Gonzalez-Cadavid NF 2002 Endogenous expression and localization of myostatin and its relation to myosin heavy chain distribution in C2C12 skeletal muscle cells. J Cell Physiol 190:170-179
    • (2002) J Cell Physiol , vol.190 , pp. 170-179
    • Artaza, J.N.1    Bhasin, S.2    Mallidis, C.3    Taylor, W.4    Ma, K.5    Gonzalez-Cadavid, N.F.6
  • 43
    • 0036270763 scopus 로고    scopus 로고
    • The subcellular destinations of APC proteins
    • Bienz M 2002 The subcellular destinations of APC proteins. Nat Rev Mol Cell Biol 3:328-338
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 328-338
    • Bienz, M.1
  • 45
    • 0030987826 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic localization of adenomatous polyposis coli protein
    • USA
    • Neufeld KL, White RL 1997 Nuclear and cytoplasmic localization of adenomatous polyposis coli protein. Proc Natl Acad Sci USA 94:3034-3039
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 3034-3039
    • Neufeld, K.L.1    White, R.L.2
  • 46
    • 0035167598 scopus 로고    scopus 로고
    • Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein
    • Zhang F, White RL, Neufeld KL 2001 Cell density and phosphorylation control the subcellular localization of adenomatous polyposis coli protein. Mol Cell Biol 21:8143-8156
    • (2001) Mol Cell Biol , vol.21 , pp. 8143-8156
    • Zhang, F.1    White, R.L.2    Neufeld, K.L.3
  • 47
    • 0029062839 scopus 로고
    • Transcriptional regulation of gene expression during adipocyte differentiation
    • MacDougald OA, Lane MD 1995 Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem 64:345-373
    • (1995) Annu Rev Biochem , vol.64 , pp. 345-373
    • MacDougald, O.A.1    Lane, M.D.2
  • 49
    • 0142254155 scopus 로고    scopus 로고
    • A transcriptional response to Wnt protein in human embryonic carcinoma cells
    • Willert J, Epping M, Pollack JR, Brown PO, Nusse R 2002 A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol 2:8
    • (2002) BMC Dev Biol , vol.2 , pp. 8
    • Willert, J.1    Epping, M.2    Pollack, J.R.3    Brown, P.O.4    Nusse, R.5
  • 52
    • 0035824617 scopus 로고    scopus 로고
    • SRY interacts with and negatively regulates androgen receptor transcriptional activity
    • Yuan X, Lu ML, Li T, Balk SP 2001 SRY interacts with and negatively regulates androgen receptor transcriptional activity. J Biol Chem 276:46647-46654
    • (2001) J Biol Chem , vol.276 , pp. 46647-46654
    • Yuan, X.1    Lu, M.L.2    Li, T.3    Balk, S.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.