Genetic analysis of the SIRT1 gene promoter in myocardial infarction

Biochemical and Biophysical Research Communications

Volumn 426, Issue 2, 2012, Pages 232-236

  Cui, Yinghua ^a   Wang, Haihua ^a   Chen, Houzao ^b   Pang, Shuchao ^a   Wang, Lin ^c   Liu, Depei ^b   Yan, Bo ^a  

^a JINING MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Myocardial infarction; Promoter; Sequence variants; SIRT1

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SURTUIN 1 GENE;

FEMALE; GENETIC TESTING; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SIRTUIN 1;

EID: 84866363675     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.071     Document Type: Article

References (53)

1. Kathiresan S., Srivastava D. Genetics of human cardiovascular disease. Cell 2012, 148:1242-1257.
2. Musunuru K., Kathiresan S. Genetics of coronary artery disease. Annu. Rev. Genomics Hum. Genet 2010, 11:91-108.
3. Schunkert H., Erdmann J., Samani N.J. Genetics of myocardial infarction: a progress report. Eur. Heart J. 2010, 31:918-925.
4. Imai S., Armstrong C.M., Kaeberlein M., Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000, 403:795-800.
5. Finkel T., Deng C.X., Mostoslavsky R. Recent progress in the biology and physiology of sirtuins. Nature 2009, 460:587-591.
6. Haigis M.C., Sinclair D.A. Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 2010, 5:253-295.
7. Horio Y., Hayashi T., Kuno A., Kunimoto R. Cellular and molecular effects of sirtuins in health and disease. Clin. Sci. (Lond.) 2011, 121:191-203.
8. Houtkooper R.H., Pirinen E., Auwerx J. Sirtuins as regulators of metabolism and healthspan. Nat. Rev. Mol. Cell Biol. 2012, 13:225-238.
9. Sundaresan N.R., Pillai V.B., Gupta M.P. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J. Mol. Cell. Cardiol. 2011, 51:614-618.
10. Tanno M., Kuno A., Horio Y., Miura T. Emerging beneficial roles of sirtuins in heart failure. Basic Res. Cardiol. 2012, 107:273.
11. Yamamoto T., Sadoshima J. Protection of the heart against ischemia/reperfusion by silent information regulator 1. Trends Cardiovasc. Med. 2011, 21:27-32.
12. Hsu C.P., Zhai P., Yamamoto T., et al. Silent information regulator 1 protects the heart from ischemia/reperfusion. Circulation 2010, 122:2170-2182.
13. Vinciguerra M., Santini M.P., Martinez C., et al. MIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart. Aging Cell 2012, 11:139-149.
14. Tanno M., Kuno A., Yano T., et al. Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure. J. Biol. Chem. 2010, 285:8375-8382.
15. Alcendor R.R., Kirshenbaum L.A., Imai S., Vatner S.F., Sadoshima J. Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ. Res. 2004, 95:971-980.
16. Chen C.J., Yu W., Fu Y.C., Wang X., Li J.L., Wang W. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem. Biophys. Res. Commun. 2009, 378:389-393.
17. Hariharan N., Maejima Y., Nakae J., Paik J., Depinho R.A., Sadoshima J. Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes. Circ. Res. 2010, 107:1470-1482.
18. Lee I.H., Cao L., Mostoslavsky R., et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc. Natl. Acad. Sci. USA 2008, 105:3374-3379.
19. Potente M., Ghaeni L., Baldessari D., et al. SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev. 2007, 21:2644-2658.
20. Zhang Q.J., Wang Z., Chen H.Z., et al. Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc. Res. 2008, 80:191-199.
21. Cheng H.L., Mostoslavsky R., Saito S., et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci. USA 2003, 100:10794-10799.
22. McBurney M.W., Yang X., Jardine K., et al. The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis. Mol. Cell. Biol. 2003, 23:38-54.
23. Alcendor R.R., Gao S., Zhai P., et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ. Res. 2007, 100:1512-1521.
24. Kawashima T., Inuzuka Y., Okuda J., et al. Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. J. Mol. Cell. Cardiol. 2011, 51:1026-1036.
25. Wu G., Liu L., Huang J., et al. Alterations of autophagic-lysosomal system in the peripheral leukocytes of patients with myocardial infarction. Clin. Chim. Acta 2011, 412:1567-1571.
26. Frye R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophys. Res. Commun. 1999, 260:273-279.
27. Voelter-Mahlknecht S., Mahlknecht U. Cloning, chromosomal characterization and mapping of the NAD-dependent histone deacetylases gene sirtuin 1. Int. J. Mol. Med. 2006, 17:59-67.
28. Afshar G., Murnane J.P. Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. Gene 1999, 234:161-168.
29. Nemoto S., Fergusson M.M., Finkel T. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 2004, 306:2105-2108.
30. Noriega L.G., Feige J.N., Canto C., et al. CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability. EMBO Rep. 2011, 12:1069-1076.
31. Clark S.J., Falchi M., Olsson B., et al. Association of sirtuin 1 (SIRT1) gene SNPs and transcript expression levels with severe obesity. Obesity (Silver Spring). 2012, 20:178-185.
32. Zillikens M.C., van Meurs J.B., Rivadeneira F., et al. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes 2009, 58:2828-2834.
33. Shimoyama Y., Mitsuda Y., Tsuruta Y., Suzuki K., Hamajima N., Niwa T. SIRTUIN 1 gene polymorphisms are associated with cholesterol metabolism and coronary artery calcification in Japanese hemodialysis patients. J. Ren. Nutr. 2012, 22:114-119.
34. Zhang A., Wang H., Qin X., Pang S., Yan B. Genetic analysis of SIRT1 gene promoter in sporadic Parkinson's disease. Biochem. Biophys. Res. Commun. 2012, 422:693-696.
35. J. Shan, S. Pang, H. Wanyan, W. Xie, X. Qin, B. Yan, Genetic analysis of the SIRT gene promoter in ventricular septal defects, Biochem. Biophys. Res. Commun. (2012), in press.
36. Ravikumar B., Sarkar S., Davies J.E., et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol. Rev. 2010, 90:1383-1435.
37. Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
38. Levine B., Mizushima N., Virgin H.W. Autophagy in immunity and inflammation. Nature 2011, 469:323-335.
39. Mizushima N., Komatsu M. Autophagy: renovation of cells and tissues. Cell 2011, 147:728-741.
40. Singh R., Kaushik S., Wang Y., et al. Autophagy regulates lipid metabolism. Nature 2009, 458:1131-1135.
41. Shibata M., Yoshimura K., Tamura H., et al. LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biochem. Biophys. Res. Commun. 2010, 393:274-279.
42. Kanamori H., Takemura G., Goto K., et al. Autophagy limits acute myocardial infarction induced by permanent coronary artery occlusion. Am. J. Physiol. Heart Circ. Physiol. 2011, 300:H2261-2271.
43. Razani B., Feng C., Coleman T., et al. Autophagy links inflammasomes to atherosclerotic progression. Cell. Metab. 2012, 15:534-544.
44. Salminen A., Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell. Signal. 2009, 21:1356-1360.
45. Gerhart-Hines Z., Rodgers J.T., Bare O., et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J. 2007, 26:1913-1923.
46. Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434:113-118.
47. Picard F., Kurtev M., Chung N., et al. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 2004, 429:771-776.
48. Hou X., Xu S., Maitland-Toolan K.A., et al. SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase. J. Biol. Chem. 2008, 283:20015-20026.
49. Kemper J.K., Xiao Z., Ponugoti B., et al. FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell. Metab. 2009, 10:392-404.
50. Li X., Zhang S., Blander G., Tse J.G., Krieger M., Guarente L. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol. Cell. 2007, 28:91-106.
51. Planavila A., Iglesias R., Giralt M., Villarroya F. Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation. Cardiovasc. Res. 2011, 90:276-284.
52. Camins A., Sureda F.X., Junyent F., et al. Sirtuin activators: designing molecules to extend life span. Biochim. Biophys. Acta 2010, 1799:740-749.
53. Lavu S., Boss O., Elliott P.J., Lambert P.D. Sirtuins-novel therapeutic targets to treat age-associated diseases. Nat. Rev. Drug Discov. 2008, 7:841-853.