Local anesthetic 'in-situ' toxicity during peripheral nerve blocks: Update on mechanisms and prevention

Current Opinion in Anaesthesiology

Volumn 25, Issue 5, 2012, Pages 589-595

  Nouette Gaulain, Karine ^a,b   Capdevila, Xavier ^c   Rossignol, Rodrigue ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b BORDEAUX UNIVERSITY HOSPITAL   (France)

^c MONTPELLIER UNIVERSITY HOSPITAL   (France)

Author keywords

apoptosis; local anesthetic; local toxicity; muscle; neuron

Indexed keywords

ANTIOXIDANT; BUPIVACAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RECOMBINANT ERYTHROPOIETIN; ROPIVACAINE;

APOPTOSIS; CELL DEATH; CELL ULTRASTRUCTURE; CELL VIABILITY; CLINICAL PRACTICE; CYTOLOGY; CYTOTOXICITY; DRUG SCREENING; HISTOPATHOLOGY; HUMAN; LOCAL ANESTHESIA; MAMMAL CELL; METABOLIC DISORDER; MITOCHONDRIAL ENERGY TRANSFER; MUSCLE CELL; MUSCLE INJURY; NERVE BLOCK; NERVE CELL; NEUROMUSCULAR DISEASE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PERIPHERAL NERVE; PHENOTYPE; PRIORITY JOURNAL; REVIEW; SARCOPLASMIC RETICULUM; SIDE EFFECT;

ANESTHETICS, LOCAL; ENERGY METABOLISM; HUMANS; INTRAOPERATIVE COMPLICATIONS; MITOCHONDRIA, MUSCLE; MUSCLE FIBERS, SKELETAL; NERVE BLOCK; NEURONS; PERIPHERAL NERVES;

EID: 84866358631     PISSN: 09527907     EISSN: 14736500     Source Type: Journal    
DOI: 10.1097/ACO.0b013e328357b9e2     Document Type: Review

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