Bupivacaine causes cytotoxicity in mouse C2C12 myoblast cells: Involvement of ERK and Akt signaling pathways

Acta Pharmacologica Sinica

Volumn 31, Issue 4, 2010, Pages 493-500

  Maurice, Joseph M ^a,b   Gan, Yan ^a   Ma, Fan Xin ^a   Chang, Yong Chang ^c   Hibner, Michael ^a   Huang, Yao ^a  

^a ST JOSEPH'S HOSPITAL AND MEDICAL CENTER   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Akt; Apoptosis; Cell proliferation; Cytotoxicity; Extracellular signal regulated kinase; Local anesthetic

Indexed keywords

BUPIVACAINE; LIDOCAINE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; IC 50; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYOBLAST; NONHUMAN; TOXICITY TESTING;

ANESTHETICS, LOCAL; ANIMALS; APOPTOSIS; BUPIVACAINE; CELL LINE; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; LIDOCAINE; MICE; MYOBLASTS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77952191166     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.20     Document Type: Article

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