Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes

Biochemical Journal

Volumn 447, Issue 1, 2012, Pages 125-136

  Ng, Ivan H W ^a,b   Ng, Dominic C H ^a   Jans, David A ^b   Bogoyevitch, Marie A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Cytokine; Interleukin 6 (IL 6); Nucleocytoplasmic trafficking; Signal transducer and activator of transcription 3 (STAT3); Transcription factor; Transcriptome analysis

Indexed keywords

STAT3 PROTEIN; TRANSCRIPTOME; TYROSINE;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STAT3 ALPHA GENE; STAT3 BETA GENE; UPREGULATION;

ALTERNATIVE SPLICING; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CELL NUCLEUS; CELLS, CULTURED; CYTOKINES; DNA PRIMERS; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; HEK293 CELLS; HUMANS; KINETICS; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; SRC HOMOLOGY DOMAINS; STAT3 TRANSCRIPTION FACTOR; TYROSINE;

EID: 84866355165     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120941     Document Type: Article

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