Metabolic reprogramming and two-compartment tumor metabolism: Opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells

Cell Cycle

Volumn 11, Issue 17, 2012, Pages 3280-3289

  Chiavarina, Barbara ^a   Martinez Outschoorn, Ubaldo E ^a,b   Whitaker Menezes, Diana ^a   Howell, Anthony ^c   Tanowitz, Herbert B ^c   Pestell, Richard G ^a,b   Sotgia, Federica ^a,c   Lisanti, Michael P ^a,b,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Aerobic glycolysis; Cancer associated fibroblasts; Caveolin 1; HIF 1 ; HIF 2 ; Hypoxia inducible factor; Metabolic coupling; Mitochondrial metabolism; OXPHOS; Tumor stroma

Indexed keywords

CYCLIN D1; CYTOCHROME C OXIDASE; EPIDERMAL GROWTH FACTOR RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LACTIC ACID; RAS PROTEIN;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CELL CYCLE; CONTROLLED STUDY; FIBROBLAST; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRION; TUMOR GROWTH; TUMOR VOLUME;

EID: 84866294574     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.21643     Document Type: Article

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