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Volumn 187, Issue 4, 2011, Pages 1970-1976

Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LYSINE; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

EID: 80051946936     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100841     Document Type: Article
Times cited : (66)

References (28)
  • 1
    • 0021992964 scopus 로고
    • Characterisation of macrophages infiltrating human mammary carcinomas
    • Steele, R. J., M. Brown, and O. Eremin. 1985. Characterisation of macrophages infiltrating human mammary carcinomas. Br. J. Cancer 51: 135-138. (Pubitemid 15151700)
    • (1985) British Journal of Cancer , vol.51 , Issue.1 , pp. 135-138
    • Steele, R.J.C.1    Brown, M.2    Eremin, O.3
  • 2
    • 0034266661 scopus 로고    scopus 로고
    • Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival
    • Lissbrant, I. F., P. Stattin, P. Wikstrom, J. E. Damber, L. Egevad, and A. Bergh. 2000. Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival. Int. J. Oncol. 17: 445-451.
    • (2000) Int. J. Oncol. , vol.17 , pp. 445-451
    • Lissbrant, I.F.1    Stattin, P.2    Wikstrom, P.3    Damber, J.E.4    Egevad, L.5    Bergh, A.6
  • 3
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • DOI 10.1002/path.1027
    • Bingle, L., N. J. Brown, and C. E. Lewis. 2002. The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies. J. Pathol. 196: 254-265. (Pubitemid 34189413)
    • (2002) Journal of Pathology , vol.196 , Issue.3 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 4
    • 0034021278 scopus 로고    scopus 로고
    • Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer
    • DOI 10.1002/(SICI)1096-9896(200003)190:4<430::AID-PATH538>3.0.CO;2- 6
    • Leek, R. D., N. C. Hunt, R. J. Landers, C. E. Lewis, J. A. Royds, and A. L. Harris. 2000. Macrophage infiltration is associated with VEGF and EGFR expression in breast cancer. J. Pathol. 190: 430-436. (Pubitemid 30163582)
    • (2000) Journal of Pathology , vol.190 , Issue.4 , pp. 430-436
    • Leek, R.D.1    Hunt, N.C.2    Landers, R.J.3    Lewis, C.E.4    Royds, J.A.5    Harris, A.L.6
  • 5
    • 0033780453 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas
    • Lewis, J. S., R. J. Landers, J. C. Underwood, A. L. Harris, and C. E. Lewis. 2000. Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas. J. Pathol. 192: 150-158.
    • (2000) J. Pathol. , vol.192 , pp. 150-158
    • Lewis, J.S.1    Landers, R.J.2    Underwood, J.C.3    Harris, A.L.4    Lewis, C.E.5
  • 6
    • 11244315697 scopus 로고    scopus 로고
    • Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
    • DOI 10.1182/blood-2004-07-2958
    • Manalo, D. J., A. Rowan, T. Lavoie, L. Natarajan, B. D. Kelly, S. Q. Ye, J. G. Garcia, and G. L. Semenza. 2005. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105: 659-669. (Pubitemid 40070750)
    • (2005) Blood , vol.105 , Issue.2 , pp. 659-669
    • Manalo, D.J.1    Rowan, A.2    Lavoie, T.3    Natarajan, L.4    Kelly, B.D.5    Ye, S.Q.6    Garcia, J.G.N.7    Semenza, G.L.8
  • 7
    • 10344251488 scopus 로고    scopus 로고
    • GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice
    • DOI 10.1016/j.immuni.2004.10.011, PII S1074761304003231
    • Eubank, T. D., R. Roberts, M. Galloway, Y. Wang, D. E. Cohn, and C. B. Marsh. 2004. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity 21: 831-842. (Pubitemid 39626673)
    • (2004) Immunity , vol.21 , Issue.6 , pp. 831-842
    • Eubank, T.D.1    Roberts, R.2    Galloway, M.3    Wang, Y.4    Cohn, D.E.5    Marsh, C.B.6
  • 9
    • 0030582384 scopus 로고    scopus 로고
    • Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
    • DOI 10.1006/bbrc.1996.1355
    • Kendall, R. L., G. Wang, and K. A. Thomas. 1996. Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem. Biophys. Res. Commun. 226: 324-328. (Pubitemid 26331903)
    • (1996) Biochemical and Biophysical Research Communications , vol.226 , Issue.2 , pp. 324-328
    • Kendall, R.L.1    Wang, G.2    Thomas, K.A.3
  • 10
    • 78650985962 scopus 로고    scopus 로고
    • Opposing roles for HIF-1{alpha} and HIF-2{alpha} in the regulation of angiogenesis by mononuclear phagocytes
    • Eubank, T. D., J. M. Roda, H. Liu, T. O'Neil, and C. B. Marsh. 2010. Opposing roles for HIF-1{alpha} and HIF-2{alpha} in the regulation of angiogenesis by mononuclear phagocytes. Blood 117: 323-332.
    • (2010) Blood , vol.117 , pp. 323-332
    • Eubank, T.D.1    Roda, J.M.2    Liu, H.3    O'Neil, T.4    Marsh, C.B.5
  • 11
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2alpha (HIF-2alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • Leek, R. D., K. L. Talks, F. Pezzella, H. Turley, L. Campo, N. S. Brown, R. Bicknell, M. Taylor, K. C. Gatter, and A. L. Harris. 2002. Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Res. 62: 1326-1329. (Pubitemid 34407787)
    • (2002) Cancer Research , vol.62 , Issue.5 , pp. 1326-1329
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3    Turley, H.4    Campo, L.5    Brown, N.S.6    Bicknell, R.7    Taylor, M.8    Gatter, K.C.9    Harris, A.L.10
  • 12
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
    • Talks, K. L., H. Turley, K. C. Gatter, P. H. Maxwell, C. W. Pugh, P. J. Ratcliffe, and A. L. Harris. 2000. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumorassociated macrophages. Am. J. Pathol. 157: 411-421. (Pubitemid 30626905)
    • (2000) American Journal of Pathology , vol.157 , Issue.2 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 14
    • 67651098992 scopus 로고    scopus 로고
    • Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis
    • Skuli, N., L. Liu, A. Runge, T. Wang, L. Yuan, S. Patel, L. Iruela-Arispe, M. C. Simon, and B. Keith. 2009. Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. Blood 114: 469-477.
    • (2009) Blood , vol.114 , pp. 469-477
    • Skuli, N.1    Liu, L.2    Runge, A.3    Wang, T.4    Yuan, L.5    Patel, S.6    Iruela-Arispe, L.7    Simon, M.C.8    Keith, B.9
  • 15
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • DOI 10.1023/A:1008942828960
    • Clausen, B. E., C. Burkhardt, W. Reith, R. Renkawitz, and I. Förster. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8: 265-277. (Pubitemid 29523965)
    • (1999) Transgenic Research , vol.8 , Issue.4 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 16
    • 0034126478 scopus 로고    scopus 로고
    • Detection of circulating melanoma cells by RT-PCR amplification of three different melanocyte-specific mRNAs in a mouse model
    • DOI 10.1034/j.1600-0749.2000.130311.x
    • Tsukamoto, K., S. Hirata, A. Osada, R. Kitamura, and S. Shimada. 2000. Detection of circulating melanoma cells by RT-PCR amplification of three different melanocyte-specific mRNAs in a mouse model. Pigment Cell Res. 13: 185-189. (Pubitemid 30400285)
    • (2000) Pigment Cell Research , vol.13 , Issue.3 , pp. 185-189
    • Tsukamoto, K.1    Hirata, S.2    Osada, A.3    Kitamura, R.4    Shimada, S.5
  • 17
    • 62449179631 scopus 로고    scopus 로고
    • Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages
    • Eubank, T. D., R. D. Roberts, M. Khan, J. M. Curry, G. J. Nuovo, P. Kuppusamy, and C. B. Marsh. 2009. Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Res. 69: 2133-2140.
    • (2009) Cancer Res. , vol.69 , pp. 2133-2140
    • Eubank, T.D.1    Roberts, R.D.2    Khan, M.3    Curry, J.M.4    Nuovo, G.J.5    Kuppusamy, P.6    Marsh, C.B.7
  • 18
    • 75549083877 scopus 로고    scopus 로고
    • A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma
    • Locke, F., J. I. Clark, and T. F. Gajewski. 2010. A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma. Cancer Chemother. Pharmacol. 65: 509-514.
    • (2010) Cancer Chemother. Pharmacol. , vol.65 , pp. 509-514
    • Locke, F.1    Clark, J.I.2    Gajewski, T.F.3
  • 19
    • 0035900804 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor alone or with dacarbazine in metastatic melanoma: A randomized phase II trial
    • DOI 10.1054/bjoc.2001.2120
    • Ravaud, A., M. Delaunay, C. Chevreau, V. Coulon, M. Debled, C. Bret-Dibat, F. Courbon, N. Gualde, and B. Nguyen Bui. 2001. Granulocyte- macrophage colony-stimulating factor alone or with dacarbazine in metastatic melanoma: A randomized phase II trial. Br. J. Cancer 85: 1467-1471. (Pubitemid 34001575)
    • (2001) British Journal of Cancer , vol.85 , Issue.10 , pp. 1467-1471
    • Ravaud, A.1    Delaunay, M.2    Chevreau, C.3    Coulon, V.4    Debled, M.5    Bret-Dibat, C.6    Courbon, F.7    Gualde, N.8    Bui, B.N.9
  • 20
    • 77957731938 scopus 로고    scopus 로고
    • Clinicopathological implications of tumour-associated macrophages and vascularization in sinonasal melanoma
    • Shi, L., D. Lei, C. Ma, F. Xu, Y. Li, Y. Wang, N. Cong, D. Liu, and X. L. Pan. 2010. Clinicopathological implications of tumour-associated macrophages and vascularization in sinonasal melanoma. J. Int. Med. Res. 38: 1276-1286.
    • (2010) J. Int. Med. Res. , vol.38 , pp. 1276-1286
    • Shi, L.1    Lei, D.2    Ma, C.3    Xu, F.4    Li, Y.5    Wang, Y.6    Cong, N.7    Liu, D.8    Pan, X.L.9
  • 23
    • 35648932996 scopus 로고    scopus 로고
    • Vasculogenesis, angiogenesis, and arteriogenesis: Mechanisms of blood vessel formation and remodeling
    • DOI 10.1002/jcb.21523
    • Semenza, G. L. 2007. Vasculogenesis, angiogenesis, and arteriogenesis: Mechanisms of blood vessel formation and remodeling. J. Cell. Biochem. 102: 840-847. (Pubitemid 350036924)
    • (2007) Journal of Cellular Biochemistry , vol.102 , Issue.4 , pp. 840-847
    • Semenza, G.L.1
  • 26
    • 0035911221 scopus 로고    scopus 로고
    • Colonystimulating factor 1 promotes progression of mammary tumors to malignancy
    • Lin, E. Y., A. V. Nguyen, R. G. Russell, and J. W. Pollard. 2001. Colonystimulating factor 1 promotes progression of mammary tumors to malignancy. J. Exp. Med. 193: 727-740.
    • (2001) J. Exp. Med. , vol.193 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4


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