메뉴 건너뛰기




Volumn 16, Issue R2, 2007, Pages

Genetic basis of polygenic hypertension

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; BLOOD PRESSURE; DISEASE MODEL; GENETIC EPISTASIS; GENETICS; HUMAN; HYPERTENSION; PATHOPHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; REVIEW; SPECIES DIFFERENCE;

EID: 84866158904     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm126     Document Type: Review
Times cited : (56)

References (92)
  • 2
    • 15944376562 scopus 로고    scopus 로고
    • Strategies for mapping and cloning quantitative trait genes in rodents
    • Flint, J., Valdar, W., Shifman, S. and Mott, R. (2005) Strategies for mapping and cloning quantitative trait genes in rodents. Nat. Rev. Genet., 6, 271-286.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 271-286
    • Flint, J.1    Valdar, W.2    Shifman, S.3    Mott, R.4
  • 3
    • 34047198196 scopus 로고    scopus 로고
    • Positional cloning of quantitative trait loci for blood pressure: how close are we?: a critical perspective
    • Deng, A.Y. (2007) Positional cloning of quantitative trait loci for blood pressure: how close are we?: a critical perspective. Hypertension, 49, 740-747.
    • (2007) Hypertension , vol.49 , pp. 740-747
    • Deng, A.Y.1
  • 4
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
    • Lander, E. and Kruglyak, L. (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat. Genet., 11, 241-247.
    • (1995) Nat. Genet. , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 5
    • 0033979807 scopus 로고    scopus 로고
    • Genetic analysis of inherited hypertension in the rat
    • Rapp, J.P. (2000) Genetic analysis of inherited hypertension in the rat. Physiol. Rev, 80, 135-172.
    • (2000) Physiol. Rev , vol.80 , pp. 135-172
    • Rapp, J.P.1
  • 6
    • 0034817026 scopus 로고    scopus 로고
    • A statistical framework for quantitative trait mapping
    • Sen, S. and Churchill, G.A. (2001) A statistical framework for quantitative trait mapping. Genetics, 159, 371-387.
    • (2001) Genetics , vol.159 , pp. 371-387
    • Sen, S.1    Churchill, G.A.2
  • 7
    • 84890512444 scopus 로고
    • Methods for the study of histocompatibility genes
    • Snell, G.D. (1948) Methods for the study of histocompatibility genes. J. Genetics, 49, 87-103.
    • (1948) J. Genetics , vol.49 , pp. 87-103
    • Snell, G.D.1
  • 8
    • 33847279382 scopus 로고    scopus 로고
    • Individual QTLs controlling quantitative variation in blood pressure inherited in a Mendelian mode
    • Duong, C., Charron, S., Deng, Y., Xiao, C., Menard, A., Roy, J. and Deng, A.Y. (2007) Individual QTLs controlling quantitative variation in blood pressure inherited in a Mendelian mode. Heredity, 98, 165-171.
    • (2007) Heredity , vol.98 , pp. 165-171
    • Duong, C.1    Charron, S.2    Deng, Y.3    Xiao, C.4    Menard, A.5    Roy, J.6    Deng, A.Y.7
  • 9
    • 3843052401 scopus 로고    scopus 로고
    • Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains
    • Ariyarajah, A., Palijan, A., Dutil, J., Prithiviraj, K., Deng, Y. and Deng, A.Y. (2004) Dissecting quantitative trait loci into opposite blood pressure effects on Dahl rat chromosome 8 by congenic strains. J. Hypertens, 22, 1495-1502.
    • (2004) J. Hypertens , vol.22 , pp. 1495-1502
    • Ariyarajah, A.1    Palijan, A.2    Dutil, J.3    Prithiviraj, K.4    Deng, Y.5    Deng, A.Y.6
  • 10
    • 25144452252 scopus 로고    scopus 로고
    • Severe hypertension caused by alleles from normotensive Lewis for a quantitative trait locus on chromosome 2
    • Eliopoulos, V., Dutil, J., Deng, Y., Grondin, M. and Deng, A.Y. (2005) Severe hypertension caused by alleles from normotensive Lewis for a quantitative trait locus on chromosome 2. Physiol. Genomics, 22, 70-75.
    • (2005) Physiol. Genomics , vol.22 , pp. 70-75
    • Eliopoulos, V.1    Dutil, J.2    Deng, Y.3    Grondin, M.4    Deng, A.Y.5
  • 11
    • 0347133175 scopus 로고    scopus 로고
    • Quantitative trait loci with opposing blood pressure effects demonstrating epistasis on Dahl rat chromosome 3
    • Palijan, A., Dutil, J. and Deng, A.Y. (2003) Quantitative trait loci with opposing blood pressure effects demonstrating epistasis on Dahl rat chromosome 3. Physiol. Genomics, 15, 1-8.
    • (2003) Physiol. Genomics , vol.15 , pp. 1-8
    • Palijan, A.1    Dutil, J.2    Deng, A.Y.3
  • 12
    • 31944435692 scopus 로고    scopus 로고
    • Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension
    • Charron, S., Duong, C., Menard, A., Roy, J., Eliopoulos, V., Lambert, R. and Deng, A.Y. (2005) Epistasis, not numbers, regulates functions of clustered Dahl rat quantitative trait loci applicable to human hypertension. Hypertension, 46, 1300-1308.
    • (2005) Hypertension , vol.46 , pp. 1300-1308
    • Charron, S.1    Duong, C.2    Menard, A.3    Roy, J.4    Eliopoulos, V.5    Lambert, R.6    Deng, A.Y.7
  • 13
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton, R.P., Gharavi, A.G. and Geller, D.S. (2001) Molecular mechanisms of human hypertension. Cell, 104, 545-556.
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 15
    • 29644436113 scopus 로고    scopus 로고
    • A loss of genome buffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension
    • Charron, S., Lambert, R., Eliopoulos, V., Duong, C., Menard, A., Roy, J. and Deng, A.Y. (2005) A loss of genome buffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension. Hum. Mol. Genet., 14, 3877-3884.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 3877-3884
    • Charron, S.1    Lambert, R.2    Eliopoulos, V.3    Duong, C.4    Menard, A.5    Roy, J.6    Deng, A.Y.7
  • 16
    • 15944396967 scopus 로고    scopus 로고
    • Genetics of human hypertension Trends Endocrinol
    • Agarwal, A., Williams, G.H. and Fisher, N.D. (2005) Genetics of human hypertension. Trends Endocrinol. Metab, 16, 127-133.
    • (2005) Metab , vol.16 , pp. 127-133
    • Agarwal, A.1    Williams, G.H.2    Fisher, N.D.3
  • 17
    • 19744370778 scopus 로고    scopus 로고
    • Genome-wide scan for hypertension in Sydney Sibships: the GENIHUSS study
    • Benjafield, A.V., Wang, W.Y., Speirs, H.J. and Morris, B.J. (2005) Genome-wide scan for hypertension in Sydney Sibships: the GENIHUSS study. Am. J. Hypertens., 18, 828-832.
    • (2005) Am. J. Hypertens. , vol.18 , pp. 828-832
    • Benjafield, A.V.1    Wang, W.Y.2    Speirs, H.J.3    Morris, B.J.4
  • 20
    • 0042062358 scopus 로고    scopus 로고
    • Salt sensitivity of Japanese from the viewpoint of gene polymorphism
    • Katsuya, T., Ishikawa, K., Sugimoto, K., Rakugi, H. and Ogihara, T. (2003) Salt sensitivity of Japanese from the viewpoint of gene polymorphism. Hypertens. Res., 26, 521-525.
    • (2003) Hypertens. Res. , vol.26 , pp. 521-525
    • Katsuya, T.1    Ishikawa, K.2    Sugimoto, K.3    Rakugi, H.4    Ogihara, T.5
  • 25
    • 0028001245 scopus 로고
    • Mapping by admixture linkage disequilibrium in human populations: limits and guidelines
    • Stephens, J.C., Briscoe, D. and O'Brien, S.J. (1994) Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. Am. J. Hum. Genet., 55, 809-824.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 809-824
    • Stephens, J.C.1    Briscoe, D.2    O'Brien, S.J.3
  • 26
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller, K.E., Pearce, C.L., Pike, M., Lander, E.S. and Hirschhorn, J.N. (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet, 33, 177-182.
    • (2003) Nat. Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 27
    • 0742288585 scopus 로고    scopus 로고
    • The complex interplay among factors that influence allelic association
    • Zondervan, K.T. and Cardon, L.R. (2004) The complex interplay among factors that influence allelic association. Nat. Rev. Genet, 5, 89-100.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 89-100
    • Zondervan, K.T.1    Cardon, L.R.2
  • 28
    • 25844510235 scopus 로고    scopus 로고
    • Shaking the tree: mapping complex disease genes with linkage disequilibrium
    • Palmer, L.J. and Cardon, L.R. (2005) Shaking the tree: mapping complex disease genes with linkage disequilibrium. Lancet, 366, 1223-1234.
    • (2005) Lancet , vol.366 , pp. 1223-1234
    • Palmer, L.J.1    Cardon, L.R.2
  • 29
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: theoretical and practical concerns
    • Wang, W.Y., Barratt, B.J., Clayton, D.G. and Todd, J.A. (2005) Genome-wide association studies: theoretical and practical concerns. Nat. Rev. Genet, 6, 109-118.
    • (2005) Nat. Rev. Genet , vol.6 , pp. 109-118
    • Wang, W.Y.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 30
    • 9644263985 scopus 로고    scopus 로고
    • 'Racial' differences in genetic effects for complex diseases
    • Ioannidis, J.P., Ntzani, E.E. and Trikalinos, T.A. (2004) 'Racial' differences in genetic effects for complex diseases. Nat. Genet, 36, 1312-1318.
    • (2004) Nat. Genet , vol.36 , pp. 1312-1318
    • Ioannidis, J.P.1    Ntzani, E.E.2    Trikalinos, T.A.3
  • 31
    • 33645473132 scopus 로고    scopus 로고
    • Pharmacogenomics and pharmacogenetics of hypertension: update and perspectives-the adducin paradigm
    • Manunta, P. and Bianchi, G. (2006) Pharmacogenomics and pharmacogenetics of hypertension: update and perspectives-the adducin paradigm. J. Am. Soc. Nephrol., 17, S30-S35.
    • (2006) J. Am. Soc. Nephrol. , vol.17
    • Manunta, P.1    Bianchi, G.2
  • 32
    • 0037385533 scopus 로고    scopus 로고
    • Defining the blood pressure QTL on chromosome 7 in Dahl rats by a 177-kb congenic segment containing Cyp11b1
    • Garrett, M.R. and Rapp, J.P. (2003) Defining the blood pressure QTL on chromosome 7 in Dahl rats by a 177-kb congenic segment containing Cyp11b1. Mamm. Genome, 14, 268-273.
    • (2003) Mamm. Genome , vol.14 , pp. 268-273
    • Garrett, M.R.1    Rapp, J.P.2
  • 34
    • 33646837861 scopus 로고    scopus 로고
    • Association of the beta2-adrenergic receptor gene with essential hypertension in the non-Han Chinese Yi minority human population
    • Wu, H., Tang, W., Li, H., Zhou, X., Yang, Y., Yu, H., Li, K., Xiao, C. and Deng, A.Y. (2006) Association of the beta2-adrenergic receptor gene with essential hypertension in the non-Han Chinese Yi minority human population. J. Hypertens., 24, 1041-1047.
    • (2006) J. Hypertens. , vol.24 , pp. 1041-1047
    • Wu, H.1    Tang, W.2    Li, H.3    Zhou, X.4    Yang, Y.5    Yu, H.6    Li, K.7    Xiao, C.8    Deng, A.Y.9
  • 35
    • 33750588294 scopus 로고    scopus 로고
    • Functional significance of single nucleotide polymorphisms within the 5'-flanking region of beta2-adrenergic receptor gene
    • Wu, H., Tang, W., Li, H., Zhou, X., Yang, Y., Yu, H., Li, K., Xiao, C. and Deng, A.Y. (2006) Functional significance of single nucleotide polymorphisms within the 5'-flanking region of beta2-adrenergic receptor gene. J. Hypertens., 24, 2474-2476.
    • (2006) J. Hypertens. , vol.24 , pp. 2474-2476
    • Wu, H.1    Tang, W.2    Li, H.3    Zhou, X.4    Yang, Y.5    Yu, H.6    Li, K.7    Xiao, C.8    Deng, A.Y.9
  • 37
    • 0034619331 scopus 로고    scopus 로고
    • From the Cover: A method for fine mapping quantitative trait loci in outbred animal stocks
    • Mott, R., Talbot, C.J., Turri, M.G., Collins, A.C. and Flint, J. (2000) From the Cover: A method for fine mapping quantitative trait loci in outbred animal stocks. PNAS, 97, 12649-12654.
    • (2000) PNAS , vol.97 , pp. 12649-12654
    • Mott, R.1    Talbot, C.J.2    Turri, M.G.3    Collins, A.C.4    Flint, J.5
  • 38
    • 0031709918 scopus 로고    scopus 로고
    • Genomic scan and congenic strains for blood pressure quantitative trait loci using Dahl salt-sensitive rats
    • Garrett, M.R., Dene, H., Walder, R., Zhang, Q., Cicila, G.T., Assadnia, S., Deng, A.Y. and Rapp, J.P. (1998) Genomic scan and congenic strains for blood pressure quantitative trait loci using Dahl salt-sensitive rats. Genome Res., 8, 711-723.
    • (1998) Genome Res , vol.8 , pp. 711-723
    • Garrett, M.R.1    Dene, H.2    Walder, R.3    Zhang, Q.4    Cicila, G.T.5    Assadnia, S.6    Deng, A.Y.7    Rapp, J.P.8
  • 39
    • 18144412000 scopus 로고    scopus 로고
    • Epigenetics of hypertension in pregnancy
    • Arngrimsson, R. (2005) Epigenetics of hypertension in pregnancy. Nat. Genet., 37, 460-461.
    • (2005) Nat. Genet. , vol.37 , pp. 460-461
    • Arngrimsson, R.1
  • 42
    • 15744384640 scopus 로고    scopus 로고
    • Multiple quantitative trait loci for blood pressure interacting epistatically and additively on dahl rat chromosome 2
    • Dutil, J., Eliopoulos, V., Tremblay, J., Hamet, P., Charron, S. and Deng, A.Y. (2005) Multiple quantitative trait loci for blood pressure interacting epistatically and additively on dahl rat chromosome 2. Hypertension, 45, 557-564.
    • (2005) Hypertension , vol.45 , pp. 557-564
    • Dutil, J.1    Eliopoulos, V.2    Tremblay, J.3    Hamet, P.4    Charron, S.5    Deng, A.Y.6
  • 43
    • 1542270222 scopus 로고    scopus 로고
    • Substitution mapping of a blood pressure quantitative trait locus to a 2.73 Mb region on rat chromosome 1
    • Joe, B., Garrett, M.R., Dene, H. and Rapp, J.P. (2003) Substitution mapping of a blood pressure quantitative trait locus to a 2.73 Mb region on rat chromosome 1. J. Hypertens, 21, 2077-2084.
    • (2003) J. Hypertens , vol.21 , pp. 2077-2084
    • Joe, B.1    Garrett, M.R.2    Dene, H.3    Rapp, J.P.4
  • 44
    • 0345975524 scopus 로고    scopus 로고
    • Multiple blood pressure QTL on rat chromosome 1 defined by Dahl rat congenic strains
    • Saad, Y., Garret, M.R. and Rapp, J.P. (2001) Multiple blood pressure QTL on rat chromosome 1 defined by Dahl rat congenic strains. Physiol. Genomics, 4, 201-214.
    • (2001) Physiol. Genomics , vol.4 , pp. 201-214
    • Saad, Y.1    Garret, M.R.2    Rapp, J.P.3
  • 45
    • 0035570186 scopus 로고    scopus 로고
    • Genetic dissection of region around the Sa gene on rat chromosome 1. evidence for multiple loci affecting blood pressure
    • Frantz, S., Clemitson, J.R., Bihoreau, M.T., Gauguier, D. and Samani, N.J. (2001) Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure. Hypertension, 38, 216-221.
    • (2001) Hypertension , vol.38 , pp. 216-221
    • Frantz, S.1    Clemitson, J.R.2    Bihoreau, M.T.3    Gauguier, D.4    Samani, N.J.5
  • 46
    • 34247158693 scopus 로고    scopus 로고
    • Genetic dissection of a blood pressure quantitative trait locus on rat chromosome 1 and gene expression analysis identifies SPON1 as a novel candidate hypertension gene
    • Clemitson, J.R., Dixon, R.J., Haines, S., Bingham, A.J., Patel, B.R., Hall, L., Lo, M., Sassard, J., Charchar, F.J. and Samani, N.J. (2007) Genetic dissection of a blood pressure quantitative trait locus on rat chromosome 1 and gene expression analysis identifies SPON1 as a novel candidate hypertension gene. Circ. Res., 100, 992-999.
    • (2007) Circ. Res. , vol.100 , pp. 992-999
    • Clemitson, J.R.1    Dixon, R.J.2    Haines, S.3    Bingham, A.J.4    Patel, B.R.5    Hall, L.6    Lo, M.7    Sassard, J.8    Charchar, F.J.9    Samani, N.J.10
  • 47
    • 0031724017 scopus 로고    scopus 로고
    • Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity
    • Iwai, N., Tsujita, Y. and Kinoshita, M. (1998) Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity. Hypertension, 32, 636-638.
    • (1998) Hypertension , vol.32 , pp. 636-638
    • Iwai, N.1    Tsujita, Y.2    Kinoshita, M.3
  • 48
    • 0344378202 scopus 로고    scopus 로고
    • Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1
    • Hubner, N., Lee, Y.A., Lindpaintner, K., Ganten, D. and Kreutz, R. (1999) Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1. Hypertension, 34, 643-648.
    • (1999) Hypertension , vol.34 , pp. 643-648
    • Hubner, N.1    Lee, Y.A.2    Lindpaintner, K.3    Ganten, D.4    Kreutz, R.5
  • 49
    • 0037440746 scopus 로고    scopus 로고
    • Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10
    • Monti, J., Plehm, R., Schulz, H., Ganten, D., Kreutz, R. and Hubner, N. (2003) Interaction between blood pressure quantitative trait loci in rats in which trait variation at chromosome 1 is conditional upon a specific allele at chromosome 10. Hum. Mol. Genet, 12, 435-439.
    • (2003) Hum. Mol. Genet , vol.12 , pp. 435-439
    • Monti, J.1    Plehm, R.2    Schulz, H.3    Ganten, D.4    Kreutz, R.5    Hubner, N.6
  • 52
    • 0037440230 scopus 로고    scopus 로고
    • Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension
    • Yagil, C., Hubner, N., Kreutz, R., Ganten, D. and Yagil, Y. (2003) Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension. Physiol. Genomics, 12, 85-95.
    • (2003) Physiol. Genomics , vol.12 , pp. 85-95
    • Yagil, C.1    Hubner, N.2    Kreutz, R.3    Ganten, D.4    Yagil, Y.5
  • 53
    • 0032488891 scopus 로고    scopus 로고
    • Metabolic features of newly established congenic diabetes-prone BB
    • Kloting, I., Voigt, B. and Kovacs, P. (1998) Metabolic features of newly established congenic diabetes-prone BB. SHR rat strains. Life Sci., 62, 973-979.
    • (1998) SHR rat strains. Life Sci. , vol.62 , pp. 973-979
    • Kloting, I.1    Voigt, B.2    Kovacs, P.3
  • 54
    • 0036134391 scopus 로고    scopus 로고
    • Multiple blood pressure QTL on rat Chromosome 2 defined by congenic Dahl rats
    • Garrett, M.R. and Rapp, J.P. (2002) Multiple blood pressure QTL on rat Chromosome 2 defined by congenic Dahl rats. Mamm. Genome, 13, 41-44.
    • (2002) Mamm. Genome , vol.13 , pp. 41-44
    • Garrett, M.R.1    Rapp, J.P.2
  • 55
    • 0037015174 scopus 로고    scopus 로고
    • Reciprocal rat chromosome 2 congenic strains reveal contrasting blood pressure and heart rate QTL
    • Alemayehu, A., Breen, L., Krenova, D. and Printz, M.P. (2002) Reciprocal rat chromosome 2 congenic strains reveal contrasting blood pressure and heart rate QTL. Physiol. Genomics, 10, 199-210.
    • (2002) Physiol. Genomics , vol.10 , pp. 199-210
    • Alemayehu, A.1    Breen, L.2    Krenova, D.3    Printz, M.P.4
  • 57
    • 0035017803 scopus 로고    scopus 로고
    • Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat
    • Pravenec, M., Zidek, V., Musilova, A., Vorlicek, J., Kren, V., St Lezin, E. and Kurtz, T.W. (2001) Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat. J. Hypertens, 19, 1061-1064.
    • (2001) J. Hypertens , vol.19 , pp. 1061-1064
    • Pravenec, M.1    Zidek, V.2    Musilova, A.3    Vorlicek, J.4    Kren, V.5    St Lezin, E.6    Kurtz, T.W.7
  • 58
    • 33845750086 scopus 로고    scopus 로고
    • Substitution mapping in dahl rats identifies two distinct blood pressure quantitative trait loci within 1 12- and 1. 25-mb intervals on chromosome 3
    • Lee, S.J., Liu, J., Westcott, A.M., Vieth, J.A., DeRaedt, S.J., Yang, S., Joe, B. and Cicila, G.T. (2006) Substitution mapping in dahl rats identifies two distinct blood pressure quantitative trait loci within 1.12- and 1.25-mb intervals on chromosome 3. Genetics, 174, 2203-2213.
    • (2006) Genetics , vol.174 , pp. 2203-2213
    • Lee, S.J.1    Liu, J.2    Westcott, A.M.3    Vieth, J.A.4    DeRaedt, S.J.5    Yang, S.6    Joe, B.7    Cicila, G.T.8
  • 59
    • 33845488377 scopus 로고    scopus 로고
    • Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats
    • Duong, C., Charron, S., Xiao, C., Hamet, P., Menard, A., Roy, J. and Deng, A.Y. (2006) Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Mamm. Genome, 17, 1147-1161.
    • (2006) Mamm. Genome , vol.17 , pp. 1147-1161
    • Duong, C.1    Charron, S.2    Xiao, C.3    Hamet, P.4    Menard, A.5    Roy, J.6    Deng, A.Y.7
  • 60
    • 0346929380 scopus 로고    scopus 로고
    • Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats
    • Garrett, M.R. and Rapp, J.P. (2002) Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats. Physiol. Genomics, 8, 81-86.
    • (2002) Physiol. Genomics , vol.8 , pp. 81-86
    • Garrett, M.R.1    Rapp, J.P.2
  • 61
    • 0038342024 scopus 로고    scopus 로고
    • Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat
    • Pravenec, M., Kren, V., Krenova, D., Zidek, V., Simakova, M., Musilova, A., Vorlicek, J., Lezin, E.S. and Kurtz, T.W. (2003) Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat. Physiol. Res., 52, 285-289.
    • (2003) Physiol. Res. , vol.52 , pp. 285-289
    • Pravenec, M.1    Kren, V.2    Krenova, D.3    Zidek, V.4    Simakova, M.5    Musilova, A.6    Vorlicek, J.7    Lezin, E.S.8    Kurtz, T.W.9
  • 62
    • 18244429854 scopus 로고    scopus 로고
    • Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat
    • Kren, V., Pravenec, M., Lu, S., Krenova, D., Wang, J.M., Wang, N., Merriouns, T., Wong, A., St Lezin, E., Lau, D. et al. (1997) Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. J. Clin. Invest, 99, 577-581.
    • (1997) J. Clin. Invest , vol.99 , pp. 577-581
    • Kren, V.1    Pravenec, M.2    Lu, S.3    Krenova, D.4    Wang, J.M.5    Wang, N.6    Merriouns, T.7    Wong, A.8    St Lezin, E.9    Lau, D.10
  • 63
    • 14644437750 scopus 로고    scopus 로고
    • Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysis
    • Garrett, M.R., Meng, H., Rapp, J.P. and Joe, B. (2005) Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysis. Hypertension, 45, 451-459.
    • (2005) Hypertension , vol.45 , pp. 451-459
    • Garrett, M.R.1    Meng, H.2    Rapp, J.P.3    Joe, B.4
  • 64
    • 33846796222 scopus 로고    scopus 로고
    • Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10
    • Saad, Y., Garrett, M.R., Manickavasagam, E., Yerga-Woolwine, S., Farms, P., Radecki, T. and Joe, B. (2007) Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10. Genomics, 89, 343-353.
    • (2007) Genomics , vol.89 , pp. 343-353
    • Saad, Y.1    Garrett, M.R.2    Manickavasagam, E.3    Yerga-Woolwine, S.4    Farms, P.5    Radecki, T.6    Joe, B.7
  • 65
    • 0035726878 scopus 로고    scopus 로고
    • Two linked blood pressure QTL on chromosome 10 defined by Dahl-rat congenic strains
    • Garrett, M.R., Zhang, X., Dukhanina, O.I., Deng, A.Y. and Rapp, J.P. (2001) Two linked blood pressure QTL on chromosome 10 defined by Dahl-rat congenic strains. Hypertension, 38, 779-785.
    • (2001) Hypertension , vol.38 , pp. 779-785
    • Garrett, M.R.1    Zhang, X.2    Dukhanina, O.I.3    Deng, A.Y.4    Rapp, J.P.5
  • 66
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • Morel, L., Blenman, K.R., Croker, B.P. and Wakeland, E.K. (2001) The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc. Natl Acad. Sci. USA, 98, 1787-1792.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 67
    • 0031227375 scopus 로고    scopus 로고
    • Interval mapping and congenic strains for a blood pressure QTL on rat chromosome 13
    • Zhang, Q.Y., Dene, H., Deng, A.Y., Garrett, M.R., Jacob, H.J. and Rapp, J.P. (1997) Interval mapping and congenic strains for a blood pressure QTL on rat chromosome 13. Mamm. Genome, 8, 636-641.
    • (1997) Mamm. Genome , vol.8 , pp. 636-641
    • Zhang, Q.Y.1    Dene, H.2    Deng, A.Y.3    Garrett, M.R.4    Jacob, H.J.5    Rapp, J.P.6
  • 68
    • 0031024407 scopus 로고    scopus 로고
    • Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats
    • Jiang, J., Stec, D.E., Drummond, H., Simon, J.S., Koike, G., Jacob, H.J. and Roman, R.J. (1997) Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats. Hypertension, 29, 619-627.
    • (1997) Hypertension , vol.29 , pp. 619-627
    • Jiang, J.1    Stec, D.E.2    Drummond, H.3    Simon, J.S.4    Koike, G.5    Jacob, H.J.6    Roman, R.J.7
  • 69
    • 13344276589 scopus 로고    scopus 로고
    • Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats
    • St Lezin, E.M., Pravenec, M., Wong, A.L., Liu, W., Wang, N., Lu, S., Jacob, H.J., Roman, R.J., Stec, D.E., Wang, J.M. et al. (1996) Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J. Clin. Invest, 97, 522-527.
    • (1996) J. Clin. Invest , vol.97 , pp. 522-527
    • St Lezin, E.M.1    Pravenec, M.2    Wong, A.L.3    Liu, W.4    Wang, N.5    Lu, S.6    Jacob, H.J.7    Roman, R.J.8    Stec, D.E.9    Wang, J.M.10
  • 73
    • 18244377271 scopus 로고    scopus 로고
    • Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17
    • Grondin, M., Eliopoulos, V., Lambert, R., Deng, Y., Ariyarajah, A., Moujahidine, M., Dutil, J., Charron, S. and Deng, A.Y. (2005) Complete and overlapping congenics proving the existence of a quantitative trait locus for blood pressure on Dahl rat chromosome 17. Physiol. Genomics, 21, 112-116.
    • (2005) Physiol. Genomics , vol.21 , pp. 112-116
    • Grondin, M.1    Eliopoulos, V.2    Lambert, R.3    Deng, Y.4    Ariyarajah, A.5    Moujahidine, M.6    Dutil, J.7    Charron, S.8    Deng, A.Y.9
  • 75
    • 0024517658 scopus 로고
    • An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains
    • Pravenec, M., Klir, P., Kren, V., Zicha, J. and Kunes, J. (1989) An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains. J. Hypertens., 7, 217-221.
    • (1989) J. Hypertens. , vol.7 , pp. 217-221
    • Pravenec, M.1    Klir, P.2    Kren, V.3    Zicha, J.4    Kunes, J.5
  • 76
    • 0027285548 scopus 로고
    • The hypertensive Y chromosome elevates blood pressure in F11 normotensive rats
    • Ely, D.L., Daneshvar, H., Turner, M.E., Johnson, M.L. and Salisbury, R.L. (1993) The hypertensive Y chromosome elevates blood pressure in F11 normotensive rats. Hypertension, 21, 1071-1075.
    • (1993) Hypertension , vol.21 , pp. 1071-1075
    • Ely, D.L.1    Daneshvar, H.2    Turner, M.E.3    Johnson, M.L.4    Salisbury, R.L.5
  • 78
    • 34249287367 scopus 로고    scopus 로고
    • Neuronal Responsiveness to Central Na{thorn} in 2 Congenic Strains of Dahl Salt-Sensitive Rats
    • Huang, B.S., Ahmad, M., Deng, A.Y. and Leenen, F.H.H. (2007) Neuronal Responsiveness to Central Na{thorn} in 2 Congenic Strains of Dahl Salt-Sensitive Rats. Hypertension, 49, 1315-1320.
    • (2007) Hypertension , vol.49 , pp. 1315-1320
    • Huang, B.S.1    Ahmad, M.2    Deng, A.Y.3    Leenen, F.H.H.4
  • 79
    • 14644404384 scopus 로고    scopus 로고
    • Polymorphisms of the insertion/deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data
    • Mondry, A., Loh, M., Liu, P., Zhu, A.L. and Nagel, M. (2005) Polymorphisms of the insertion/deletion ACE and M235T AGT genes and hypertension: surprising new findings and meta-analysis of data. BMC. Nephrol, 6, 1.
    • (2005) BMC. Nephrol , vol.6 , pp. 1
    • Mondry, A.1    Loh, M.2    Liu, P.3    Zhu, A.L.4    Nagel, M.5
  • 81
    • 0033941303 scopus 로고    scopus 로고
    • Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart Lung and Blood Institute
    • Province, M.A., Boerwinkle, E., Chakravarti, A., Cooper, R., Fornage, M., Leppert, M., Risch, N. and Ranade, K. (2000) Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute. J. Hypertens., 18, 867-876.
    • (2000) J. Hypertens. , vol.18 , pp. 867-876
    • Province, M.A.1    Boerwinkle, E.2    Chakravarti, A.3    Cooper, R.4    Fornage, M.5    Leppert, M.6    Risch, N.7    Ranade, K.8
  • 82
    • 0037771145 scopus 로고    scopus 로고
    • Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis
    • Sethi, A.A., Nordestgaard, B.G. and Tybjaerg-Hansen, A. (2003) Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis. Arterioscler. Thromb. Vasc. Biol., 23, 1269-1275.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1269-1275
    • Sethi, A.A.1    Nordestgaard, B.G.2    Tybjaerg-Hansen, A.3
  • 83
    • 0030696254 scopus 로고    scopus 로고
    • Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal
    • Kunz, R., Kreutz, R., Beige, J., Distler, A. and Sharma, A.M. (1997) Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal. Hypertension, 30, 1331-1337.
    • (1997) Hypertension , vol.30 , pp. 1331-1337
    • Kunz, R.1    Kreutz, R.2    Beige, J.3    Distler, A.4    Sharma, A.M.5
  • 84
    • 33845355513 scopus 로고    scopus 로고
    • Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis
    • Sookoian, S., Gianotti, T.F., Gonzalez, C.D. and Pirola, C.J. (2007) Association of the C-344T aldosterone synthase gene variant with essential hypertension: a meta-analysis. J. Hypertens., 25, 5-13.
    • (2007) J. Hypertens. , vol.25 , pp. 5-13
    • Sookoian, S.1    Gianotti, T.F.2    Gonzalez, C.D.3    Pirola, C.J.4
  • 85
    • 33846815156 scopus 로고    scopus 로고
    • The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17.760 controls
    • Bagos, P.G., Elefsinioti, A.L., Nikolopoulos, G.K. and Hamodrakas, S.J. (2007) The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17,760 controls. J. Hypertens., 25, 487-500.
    • (2007) J. Hypertens. , vol.25 , pp. 487-500
    • Bagos, P.G.1    Elefsinioti, A.L.2    Nikolopoulos, G.K.3    Hamodrakas, S.J.4
  • 86
    • 4344599724 scopus 로고    scopus 로고
    • Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis
    • Kosmas, I.P., Tatsioni, A. and Ioannidis, J.P. (2004) Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis. J. Hypertens., 22, 1655-1662.
    • (2004) J. Hypertens. , vol.22 , pp. 1655-1662
    • Kosmas, I.P.1    Tatsioni, A.2    Ioannidis, J.P.3
  • 87
    • 33750586809 scopus 로고    scopus 로고
    • Endothelial NO synthase gene polymorphisms and hypertension: a meta-analysis
    • Zintzaras, E., Kitsios, G. and Stefanidis, I. (2006) Endothelial NO synthase gene polymorphisms and hypertension: a meta-analysis. Hypertension, 48, 700-710.
    • (2006) Hypertension , vol.48 , pp. 700-710
    • Zintzaras, E.1    Kitsios, G.2    Stefanidis, I.3
  • 89
    • 32944456004 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project
    • Rice, T., Cooper, R.S., Wu, X., Bouchard, C., Rankinen, T., Rao, D.C., Jaquish, C.E., Fabsitz, R.R. and Province, M.A. (2006) Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project. Am. J. Hypertens., 19, 270-274.
    • (2006) Am. J. Hypertens. , vol.19 , pp. 270-274
    • Rice, T.1    Cooper, R.S.2    Wu, X.3    Bouchard, C.4    Rankinen, T.5    Rao, D.C.6    Jaquish, C.E.7    Fabsitz, R.R.8    Province, M.A.9
  • 90
    • 5444222846 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3
    • Koivukoski, L., Fisher, S.A., Kanninen, T., Lewis, C.M., von Wowern, F., Hunt, S., Kardia, S.L., Levy, D., Perola, M., Rankinen, T. et al. (2004) Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3. Hum. Mol. Genet, 13, 2325-2332.
    • (2004) Hum. Mol. Genet , vol.13 , pp. 2325-2332
    • Koivukoski, L.1    Fisher, S.A.2    Kanninen, T.3    Lewis, C.M.4    von Wowern, F.5    Hunt, S.6    Kardia, S.L.7    Levy, D.8    Perola, M.9    Rankinen, T.10
  • 91
    • 11144297977 scopus 로고    scopus 로고
    • Genome scan meta-analysis for hypertension
    • Liu, W., Zhao, W. and Chase, G.A. (2004) Genome scan meta-analysis for hypertension. Am. J. Hypertens., 17, 1100-1106.
    • (2004) Am. J. Hypertens. , vol.17 , pp. 1100-1106
    • Liu, W.1    Zhao, W.2    Chase, G.A.3
  • 92
    • 33646837677 scopus 로고    scopus 로고
    • The beta2-adrenoceptor gene and hypertension: is it the promoter or the coding region or neither?
    • Hahntow, I.N., Koopmans, R.P. and Michel, M.C. (2006) The beta2-adrenoceptor gene and hypertension: is it the promoter or the coding region or neither? J. Hypertens., 24, 1003-1007.
    • (2006) J Hypertens , vol.24 , pp. 1003-1007
    • Hahntow, I.N.1    Koopmans, R.P.2    Michel, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.