Interval mapping and congenic strains for a blood pressure QTL on rat Chromosome 13

Mammalian Genome

Volumn 8, Issue 9, 1997, Pages 636-641

  Zhang, Q Y ^a   Dene, H ^a   Deng, A Y ^a   Garrett, M R ^a   Jacob, H J ^b   Rapp, J P ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RENIN;

ANIMAL; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CHROMOSOME MAP; COMPARATIVE STUDY; CROSS BREEDING; DRUG RESISTANCE; GENETIC LINKAGE; GENETIC MARKER; GENETIC POLYMORPHISM; GENETICS; HAPLOTYPE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; RAT; RAT STRAIN; SALT INTAKE;

ANIMALS; BLOOD PRESSURE; BODY WEIGHT; CHROMOSOME MAPPING; CROSSES, GENETIC; DRUG RESISTANCE; GENETIC MARKERS; GENETICS, POPULATION; HAPLOTYPES; LINKAGE (GENETICS); POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RATS; RATS, INBRED STRAINS; RENIN; SODIUM CHLORIDE, DIETARY;

ANIMALIA; RODENTIA;

EID: 0031227375     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900528     Document Type: Article

References (35)

1. Alam KY, Wang Y, Dene H, Rapp JP (1993) Renin gene nucleotide sequence of coding and regulatory regions in Dahl rats. Clin Exp Hypertens 15, 599-614
2. Blin N, Stafford DW (1976) Isolation of high-molecular-weight DNA. Nucleic Acids Res 3, 2303-2308
3. Bunag RD, Butterfield J (1982) Tail-cuff blood pressure measurement without external preheating in awake rats. Hypertension (Dallas) 4, 898-903
4. Cicila GT, Rapp JP, Wang J-M, St. Lezin E, Ng SC, Kurtz TW (1993) Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nature Genet 3, 346-353
5. Cicila GT, Rapp JP, Bloch KD, Kurtz TW, Pravenec M, Kren V, Hong CC, Quertermous T, Ng SC (1994) Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats. J Hypertens 12, 643-651
6. Darvasi A, Weinreb A, Minke V, Weller JI, Soller M (1993) Detecting marker-QTL linkage and estimating QTL gene effect and map location using a saturated genetic map. Genetics 134, 943-951
7. Dubay C, Vincent M, Samani NJ, Hilbert P, Kaiser MA, Beressi JP, Kotelevtsev Y, Beckmann JS, Soubrier F, Sassard J, Lathrop GM (1993) Genetic determinants of diastolic and pulse pressure map to different loci in Lyon hypertensive rats. Nature Genet 3, 354-357
8. Green EL (1981) Genetics and Probability in Animal Breeding Experiments (Oxford University Press, New York) p 24
9. Harris EL, Phelan E, Thompson CM, Millar JA, Grigor MR (1995) Heart mass and blood pressure have separate genetic determinants in the New Zealand genetically hypertensive (GH) rat. J. Hypertens 13, 397-404
10. Hyne V, Kearsey MJ, Pike DJ, Snape JW (1995) QTL analysis: unreliability and bias in estimation procedures. Mol Breed 1, 273-282
11. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark A, Levan G, Mao Y-P, Petterson A, Pravenec M, Simon JS, Szpirer C, Szpirer J, Trolliet MR, Winer ES, Lander ES (1995) A genetic linkage map of the laboratory rat, Rattus norvegicus. Nature Genet 9, 63-69
12. Jiang J, Stec DE, Drummond H, Simon JS, Koike G, Jacob HJ, Roman RJ (1997) Transfer of a salt-resistant renin allele raises blood pressure in Dahl salt-sensitive rats. Hypertension (Dallas) 19, 619-627
13. Kuramoto T, Mori M, Hirayama N, Saburi S, Yamada J, Serikawa T (1993). A strategy for rapid construction of genetic and physical maps in the rat. Acta Histochem Cytochem 26, 325-332
14. Kurtz TW, Simonet L, Kabra PM, Wolfe S, Chan L, Hjelle BL (1990) Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J Clin Invest 85, 1328-1332
15. Lander EP, Botstein D (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 12, 185-199
16. Lander EP, Green P, Abrahamson J, Barrow A, Daly MJ (1987) MAP-MAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1, 174-181
17. Lewis JL, Russell RJ, Warnock DG (1994) Analysis of the genetic contamination of salt-sensitive Dahl/Rapp rats. Hypertension (Dallas) 24, 255-259
18. Lincoln S, Daly M, Lander E (1992a) Mapping genes controlling quantitative traits with Mapmaker/QTL 1.1. Whitehead Institute Technical Report, 2nd ed.
19. Lincoln S, Daly M, Lander E (1992b) Constructing genetic maps with Mapmaker/Exp 3.0. Whitehead Institute Technical Report, 3rd ed.
20. Orita MY, Iwahara H, Kanazawa H, Hayashi K, Sekiya T (1989a) Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 86, 2766-2770
21. Orita MY, Suzuki Y, Sekiya T, Hayashi K (1989b) Rapid and sensitive detection of point mutations and DNA polymorphism using the polymerase chain reaction. Genomics 5, 874-879
22. Paterson A, Lander E, Lincoln S, Hewitt J, Peterson S, Tanksley S (1988) Resolution of quantitative traits into Mendelian factors using a complete RFLP linkage map. Nature 335, 721-726
23. Pravenec M, Simonet L, Kren V, Kunes J, Levan G, Szpirer J, Szpirer C, Kurtz T (1991) The rat renin gene: assignment to chromosome 13 and linkage to the regulation of blood pressure. Genomics 9, 466-472
24. Rapp JP, Dene H (1985) Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension (Dallas) 7, 340-349
25. Rapp JP, Deng AY (1995) Detection and positional cloning of blood pressure quantitative trait loci: is it possible? Hypertension (Dallas) 25, 1121-1128
26. Rapp JP, Wang SM, Dene H (1989) A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science 243, 542-544
27. Rapp JP, Wang SM, Dene H (1990) Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats. Am J Hypertens 3, 391-396
28. Rapp JP, Dene H, Deng A (1994) Seven renin alleles in rats and their effects on blood pressure. J Hypertens 12, 349-355
29. Remmers EF, Goldmuntz EA, Zha HB, Mathern P, Du Y, Crofford LJ, Wilder RL (1993) Linkage map of nine loci defined by polymorphic DNA markers assigned to rat chromosome 13. Genomics 18, 277-282
30. Samani NJ, Gauguier D, Vincent M, Kaiser MA, Bihoreau M-T, Lodwick D, Wallis R, Parent V, Kimber P, Rattray F, Thompson JR, Sassard J, Lathrop M (1996) Analysis of quantitative trait loci for blood pressure on rat chromosomes 2 and 13. Hypertension (Dallas) 28, 1118-1122
31. Serikawa T, Kuramoto T, Hilbert P, Mori M, Yamada J, Dubay CJ, Lind-paintner K, Ganten D, Guenet JL, Lathrop GM, Beckmann JS (1992) Rat gene mapping using PCR-analyzed microsatellites. Genetics 131, 701-721
32. Silver LM (1995) Mouse Genetics. Concepts and Applications. (New York: Oxford University Press), pp 43-49
33. St. Lezin EM, Pravenec M, Wong A, Wang J-M, Merriouns T, Newton S, Stec DE, Roman RJ, Lau D, Morris Jr RC, Kurtz TW (1994) Genetic contamination of Dahl SS/Jr rats. Hypertension (Dallas) 23, 786-790
34. St. Lezin EM, Pravenic M, Wong AL, Liu W, Wang N, Lu S, Jacob HJ. Roman RJ, Stec DE, Wang JM, Reid IA, Kurtz TW (1996) Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt-resistant rats. J Clin Invest 97, 522-527
35. 2 rats of SHR-WKY cross. Clin Exp Hypertens 15, 797-805