A statistical framework for quantitative trait mapping

Genetics

Volumn 159, Issue 1, 2001, Pages 371-387

  Sen, Śaunak ^a   Churchill, Gary A ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; BAYES THEOREM; COMPUTER PROGRAM; GENE LOCATION; GENE MAPPING; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MODEL; GENOTYPE; HYPERTENSION; INBREEDING; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; STATISTICAL ANALYSIS; SYSTEM ANALYSIS;

ALGORITHMS; ANIMALS; BLOOD PRESSURE; CHROMOSOME MAPPING; CROSSES, GENETIC; GENOME; GENOTYPE; HYPERTENSION; LINKAGE (GENETICS); MICE; MODELS, GENETIC; MODELS, STATISTICAL; MONTE CARLO METHOD; PHENOTYPE; QUANTITATIVE TRAIT, HERITABLE; SOFTWARE;

EID: 0034817026     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. A review of methods for identifying QTLs in experimental crosses
2. Mapping time-to-death quantitative trait loci in a mouse cross with high survival rates
3. Empirical threshold values for quantitative trait mapping
4. Experimental strategies for the genetic dissection of complex traits in animal models
5. Maximum likelihood from incomplete data via the EM algorithm
6. Statistical methods for mapping quantitative trait loci from a dense set of markers
7. Reversible jump Markov chain Monte Carlo computation and Bayesian model determination
8. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
9. Bayesian analysis of linkage between genetic markers and quantitative trait loci. II. Combining prior knowledge with experimental evidence
10. A general mixture model for mapping quantitative trait loci by using molecular markers
11. High resolution of quantitative traits into multiple loci via interval mapping
12. Multiple trait analysis of genetic mapping for quantitative trait loci
13. On the difference between maximum likelihood and regression interval mapping in the analysis of quantitative trait loci
14. Multiple interval mapping for quantitative trait loci
15. Bayes factors
16. Asymptotic theory for gene mapping
17. Interval mapping of quantitative trait loci employing correlated trait complexes
18. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
19. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
20. Construction of multilocus genetic linkage maps in humans
21. Systematic detection of errors in genetic linkage data
22. Sequential tests for the detection of linkage
23. Genetic analysis of inherited hypertension in the rat
24. Single-and multiple-trait mapping analysis of linked quantitative trait loci: Some asymptotic analytical approximations
25. Inference and missing data
26. A Bayesian approach to detect quantitative trait loci using Markov chain Monte Carlo
27. The association of size difference with seed-coat pattern and pigmentation in phaseolus vulgaris
28. Two-trait-locus linkage analysis: A powerful strategy for mapping complex genetic traits
29. Estimating the dimension of a model
30. Genetic identification of multiple loci that control breast cancer susceptibility in the rat
31. Bayesian mapping of multiple quantitative trait loci from incomplete outbred offspring data
32. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci
33. Location of polygenes
34. Mapping-linked quantitative trait loci using Bayesian analysis and Markov chain Monte Carlo algorithms
35. Linkage mapping in experimental crosses: The robustness of single-gene models
36. Theoretical basis of separation of multiple linked gene effects on mapping quantitative trait loci
37. Precision mapping of quantitative trait loci
38. Statistical analysis of crossover interference using the chi-square model