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Volumn 84, Issue 3, 2012, Pages 261-268

Molecular mechanisms of external genitalia development

Author keywords

Development; External genitalia; Hypospadias

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN; CHLORPHENOTANE; ENDOCRINE DISRUPTOR; ESTROGEN; PHTHALIC ACID; SEX HORMONE; TESTOSTERONE;

EID: 84866016955     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2012.06.003     Document Type: Review
Times cited : (107)

References (82)
  • 1
    • 68149101449 scopus 로고    scopus 로고
    • Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain
    • Agrawal R, Wessely O, Anand A, Singh L, Aggarwal RK. Male-specific expression of Sox9 during gonad development of crocodile and mouse is mediated by alternative splicing of its proline-glutamine-alanine rich domain. FEBS Journal 2009, 276(15):4184-4196.
    • (2009) FEBS Journal , vol.276 , Issue.15 , pp. 4184-4196
    • Agrawal, R.1    Wessely, O.2    Anand, A.3    Singh, L.4    Aggarwal, R.K.5
  • 3
    • 0033950927 scopus 로고    scopus 로고
    • Hypospadias and urethral development
    • Baskin LS. Hypospadias and urethral development. Journal of Urology 2000, 163(3):951-956.
    • (2000) Journal of Urology , vol.163 , Issue.3 , pp. 951-956
    • Baskin, L.S.1
  • 8
    • 33645022280 scopus 로고    scopus 로고
    • Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice
    • 5:4
    • Buckley J, Willingham E, Agras K, Baskin LS. Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice. Environmental Health 2006, Feb 21(5:4).
    • (2006) Environmental Health , vol.Feb 21
    • Buckley, J.1    Willingham, E.2    Agras, K.3    Baskin, L.S.4
  • 11
    • 79955895856 scopus 로고    scopus 로고
    • The relationship between anogenital distance, fatherhood, and fertility in adult men.
    • , 10.1371/journal.pone.0018973
    • Eisenberg, Michael L., Hsieh Michael H., Rustin Chanc Walters, Ross Krasnow, Larry I Lipshultz. The relationship between anogenital distance, fatherhood, and fertility in adult men. PloS One 2011, 6(5):e18973. , 10.1371/journal.pone.0018973.
    • (2011) PloS One , vol.6 , Issue.5
    • Eisenberg1    Michael, L.2    Hsieh Michael, H.3    Rustin Chanc Walters4    Ross Krasnow5    Larry I, Lipshultz.6
  • 12
    • 1842434975 scopus 로고    scopus 로고
    • Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome
    • Fisher JS. Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome. Reproduction 2004, 127(3):305-315.
    • (2004) Reproduction , vol.127 , Issue.3 , pp. 305-315
    • Fisher, J.S.1
  • 14
    • 80054886955 scopus 로고    scopus 로고
    • Prenatal environmental risk factors for genital malformations in a population of 1442 French male newborns: a nested case-control study
    • Gaspari L, Paris F, Jandel C, Kalfa N, Orsini M, Daures JP, Sultan C Prenatal environmental risk factors for genital malformations in a population of 1442 French male newborns: a nested case-control study. Human Reproduction 2011, 26(11):3155-3162.
    • (2011) Human Reproduction , vol.26 , Issue.11 , pp. 3155-3162
    • Gaspari, L.1    Paris, F.2    Jandel, C.3    Kalfa, N.4    Orsini, M.5    Daures, J.P.6    Sultan, C.7
  • 15
    • 0015089340 scopus 로고
    • Androgenicity in the rat fetus of metabolites of testosterone and antagonism by cyproterone acetate
    • Goldman AS, Baker MK. Androgenicity in the rat fetus of metabolites of testosterone and antagonism by cyproterone acetate. Endocrinology 1971, 89(1):276-280.
    • (1971) Endocrinology , vol.89 , Issue.1 , pp. 276-280
    • Goldman, A.S.1    Baker, M.K.2
  • 16
    • 0343962125 scopus 로고    scopus 로고
    • Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat
    • Gray LE, Ostby J, Monosson E, Kelce WR. Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat. Toxicology and Industrial Health 1999, 15(1-2):48-64.
    • (1999) Toxicology and Industrial Health , vol.15 , Issue.1-2 , pp. 48-64
    • Gray, L.E.1    Ostby, J.2    Monosson, E.3    Kelce, W.R.4
  • 17
    • 0343090362 scopus 로고    scopus 로고
    • Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl-and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat
    • Gray LE, Wolf C, Lambright C, Mann P, Price M, Cooper RL, Ostby J. Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p'-DDE, and ketoconazole) and toxic substances (dibutyl-and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat. Toxicology and Industrial Health 1999, 15(1-2):94-118.
    • (1999) Toxicology and Industrial Health , vol.15 , Issue.1-2 , pp. 94-118
    • Gray, L.E.1    Wolf, C.2    Lambright, C.3    Mann, P.4    Price, M.5    Cooper, R.L.6    Ostby, J.7
  • 20
    • 33947245423 scopus 로고    scopus 로고
    • Prenatal testosterone exposure permanently masculinizes anogenital distance, nipple development, and reproductive tract morphology in female Sprague-Dawley rats
    • Hotchkiss AK, Lambright CS, Ostby JS, Parks-Saldutti L, Vandenbergh JG, Gray LE Prenatal testosterone exposure permanently masculinizes anogenital distance, nipple development, and reproductive tract morphology in female Sprague-Dawley rats. Toxicological Sciences 2007, 96(2):335-345.
    • (2007) Toxicological Sciences , vol.96 , Issue.2 , pp. 335-345
    • Hotchkiss, A.K.1    Lambright, C.S.2    Ostby, J.S.3    Parks-Saldutti, L.4    Vandenbergh, J.G.5    Gray, L.E.6
  • 21
    • 35348991734 scopus 로고    scopus 로고
    • In utero exposure to the environmental androgen trenbolone masculinizes female Sprague-Dawley rats
    • Hotchkiss AK, Furr J, Makynen EA, Ankley GT, Gray LE In utero exposure to the environmental androgen trenbolone masculinizes female Sprague-Dawley rats. Toxicological Letters 2007, 174(1-3):31-41.
    • (2007) Toxicological Letters , vol.174 , Issue.1-3 , pp. 31-41
    • Hotchkiss, A.K.1    Furr, J.2    Makynen, E.A.3    Ankley, G.T.4    Gray, L.E.5
  • 22
    • 34548513563 scopus 로고    scopus 로고
    • In utero exposure to benxophenone-2 causes hypospadias through an estrogen receptor dependent mechanism
    • Hsieh MH, Grantham EC, Liu B, Macapagal R, Willingham E, Baskin LS. In utero exposure to benxophenone-2 causes hypospadias through an estrogen receptor dependent mechanism. Journal of Urology 2007, 178(4 Pt 2):1637-1642.
    • (2007) Journal of Urology , vol.178 , Issue.4 PART 2 , pp. 1637-1642
    • Hsieh, M.H.1    Grantham, E.C.2    Liu, B.3    Macapagal, R.4    Willingham, E.5    Baskin, L.S.6
  • 23
    • 0036791441 scopus 로고    scopus 로고
    • P63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract
    • Ince TA, Cviko AP, Quade BJ, Yang A, McKeon FD, Mutter GL, Crum CP. P63 Coordinates anogenital modeling and epithelial cell differentiation in the developing female urogenital tract. American Journal of Pathology 2002, 161(4):1111-1117.
    • (2002) American Journal of Pathology , vol.161 , Issue.4 , pp. 1111-1117
    • Ince, T.A.1    Cviko, A.P.2    Quade, B.J.3    Yang, A.4    McKeon, F.D.5    Mutter, G.L.6    Crum, C.P.7
  • 24
    • 0031020234 scopus 로고    scopus 로고
    • DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita
    • Ito M, Yu R, Jameson JL. DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita. Molecular and Cellular Biology 1997, 17(3):1476-1483.
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.3 , pp. 1476-1483
    • Ito, M.1    Yu, R.2    Jameson, J.L.3
  • 25
    • 62249208699 scopus 로고    scopus 로고
    • Mutation analysis of FOXF2 in patients with disorders of sex development (DSD) in combination with cleft palate
    • Jochumsen U, Werner R, Miura N, Richyer-Unruh A, Hiort O, Holterhus PM. Mutation analysis of FOXF2 in patients with disorders of sex development (DSD) in combination with cleft palate. Sexual Development 2008, 2(6):302-308.
    • (2008) Sexual Development , vol.2 , Issue.6 , pp. 302-308
    • Jochumsen, U.1    Werner, R.2    Miura, N.3    Richyer-Unruh, A.4    Hiort, O.5    Holterhus, P.M.6
  • 26
    • 79960044917 scopus 로고    scopus 로고
    • Exposure to phthalates: reproductive outcome and children health. A review of epidemiological studies
    • Jurewicz J, Hanke W. Exposure to phthalates: reproductive outcome and children health. A review of epidemiological studies. International Journal of Occupational Medicine and Environmental Health 2011, 24(2):115-141.
    • (2011) International Journal of Occupational Medicine and Environmental Health , vol.24 , Issue.2 , pp. 115-141
    • Jurewicz, J.1    Hanke, W.2
  • 30
    • 0033785839 scopus 로고    scopus 로고
    • Urethral development in the fetal rabbit and insuction of hypospadias: a model for human development
    • Kurzrock EA, Jegatheesan P, Cunha GR, Baskin LS. Urethral development in the fetal rabbit and insuction of hypospadias: a model for human development. Journal of Urology 2000, 164(5):1786-1792.
    • (2000) Journal of Urology , vol.164 , Issue.5 , pp. 1786-1792
    • Kurzrock, E.A.1    Jegatheesan, P.2    Cunha, G.R.3    Baskin, L.S.4
  • 31
    • 84860470386 scopus 로고    scopus 로고
    • Masculinization of the distal tubular and external genitalia in female sheep with prenatal androgen exposure.
    • , 10.1177/0300985811419533
    • Lamm CG, Hastie PM, Evans NP, Robinson JE. Masculinization of the distal tubular and external genitalia in female sheep with prenatal androgen exposure. Veterinary Pathology 2012, 49(3):546-551. , 10.1177/0300985811419533.
    • (2012) Veterinary Pathology , vol.49 , Issue.3 , pp. 546-551
    • Lamm, C.G.1    Hastie, P.M.2    Evans, N.P.3    Robinson, J.E.4
  • 33
    • 47249139928 scopus 로고    scopus 로고
    • BAC transgenic analysis reveals enhancers sufficient for Hoxa13 and neighborhood gene expression in mouse embryonic distal limbs and genital bud
    • Lehoczky JA, Innis JW. BAC transgenic analysis reveals enhancers sufficient for Hoxa13 and neighborhood gene expression in mouse embryonic distal limbs and genital bud. Evolution and Development 2008, 10(4):421-432.
    • (2008) Evolution and Development , vol.10 , Issue.4 , pp. 421-432
    • Lehoczky, J.A.1    Innis, J.W.2
  • 34
    • 33748565327 scopus 로고    scopus 로고
    • Gene expression profiles in mouse urethral development
    • Li J, Willingham E, Baskin LS. Gene expression profiles in mouse urethral development. BJU International 2006, 98(4):880-885.
    • (2006) BJU International , vol.98 , Issue.4 , pp. 880-885
    • Li, J.1    Willingham, E.2    Baskin, L.S.3
  • 35
    • 70450159800 scopus 로고    scopus 로고
    • Temporal and spatial dissection of Shh signaling in genital tubercle development
    • Lin C, Yin Y, Veith GM, Fisher AV, Long F, Ma L. Temporal and spatial dissection of Shh signaling in genital tubercle development. Development 2009, 136(23):3959-3967.
    • (2009) Development , vol.136 , Issue.23 , pp. 3959-3967
    • Lin, C.1    Yin, Y.2    Veith, G.M.3    Fisher, A.V.4    Long, F.5    Ma, L.6
  • 36
    • 52449090183 scopus 로고    scopus 로고
    • Tissue-specific requirements of beta-catenin in external genitalia development
    • Lin C, Yin Y, Long F, Ma L. Tissue-specific requirements of beta-catenin in external genitalia development. Development 2008, 135(16):2815-2825.
    • (2008) Development , vol.135 , Issue.16 , pp. 2815-2825
    • Lin, C.1    Yin, Y.2    Long, F.3    Ma, L.4
  • 38
    • 33646088731 scopus 로고    scopus 로고
    • Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation
    • Liu B, Agras K, Willingham E, Vilela ML, Baskin LS. Activating transcription factor 3 is estrogen-responsive in utero and upregulated during sexual differentiation. Hormone Research 2006, 65(5):217-222.
    • (2006) Hormone Research , vol.65 , Issue.5 , pp. 217-222
    • Liu, B.1    Agras, K.2    Willingham, E.3    Vilela, M.L.4    Baskin, L.S.5
  • 39
    • 49449114692 scopus 로고    scopus 로고
    • Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta 1 expression in fetal mouse genital tubercles
    • Liu X, He DW, Zhang DY, Lin T, Wei GH. Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta 1 expression in fetal mouse genital tubercles. Journal of Toxicology and Environmental Health A 2008, 71(19):1289-1294.
    • (2008) Journal of Toxicology and Environmental Health A , vol.71 , Issue.19 , pp. 1289-1294
    • Liu, X.1    He, D.W.2    Zhang, D.Y.3    Lin, T.4    Wei, G.H.5
  • 40
    • 0034894623 scopus 로고    scopus 로고
    • Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues
    • McIntyre BS, Barlow NJ, Foster PM. Androgen-mediated development in male rat offspring exposed to flutamide in utero: permanence and correlation of early postnatal changes in anogenital distance and nipple retention with malformations in androgen-dependent tissues. Toxicological Sciences 2001, 62(2):236-249.
    • (2001) Toxicological Sciences , vol.62 , Issue.2 , pp. 236-249
    • McIntyre, B.S.1    Barlow, N.J.2    Foster, P.M.3
  • 46
    • 0041669549 scopus 로고    scopus 로고
    • Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia
    • Morgan EA, Nguyen SB, Scott V, Stadler HS. Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development 2003, 130(14):3095-3109.
    • (2003) Development , vol.130 , Issue.14 , pp. 3095-3109
    • Morgan, E.A.1    Nguyen, S.B.2    Scott, V.3    Stadler, H.S.4
  • 47
    • 77956898039 scopus 로고    scopus 로고
    • Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infants
    • Nassar N, Abeywardana P, Barker A, Bower C. Parental occupational exposure to potential endocrine disrupting chemicals and risk of hypospadias in infants. Occupational and Environmental Medicine 2010, 67(9):585-589.
    • (2010) Occupational and Environmental Medicine , vol.67 , Issue.9 , pp. 585-589
    • Nassar, N.1    Abeywardana, P.2    Barker, A.3    Bower, C.4
  • 48
    • 43049122752 scopus 로고    scopus 로고
    • Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processes
    • Nishida H, Miyagawa S, Matsumaru D, Wada Y, Satoh Y, Ogino Y, Fukuda S, Iguchi T, Yamada G. Gene expression analyses on embryonic external genitalia: identification of regulatory genes possibly involved in masculinization processes. Congenital Anomalies 2008, 48(2):63-67.
    • (2008) Congenital Anomalies , vol.48 , Issue.2 , pp. 63-67
    • Nishida, H.1    Miyagawa, S.2    Matsumaru, D.3    Wada, Y.4    Satoh, Y.5    Ogino, Y.6    Fukuda, S.7    Iguchi, T.8    Yamada, G.9
  • 49
    • 4544263567 scopus 로고    scopus 로고
    • Androgen dependent development of a modified anal fin, gonopodium, as a model to understand the mechanism of secondary sexual character expression in vertebrates
    • Ogino Y, Katoh H, Yamada G. Androgen dependent development of a modified anal fin, gonopodium, as a model to understand the mechanism of secondary sexual character expression in vertebrates. FEBS Letters 2004, 575(1-3):119-126.
    • (2004) FEBS Letters , vol.575 , Issue.1-3 , pp. 119-126
    • Ogino, Y.1    Katoh, H.2    Yamada, G.3
  • 50
    • 33846795960 scopus 로고    scopus 로고
    • Effects of prenatal exposure to styrene trimers on genital organs and hormones in male rats
    • Ohyama K, Satoh K, Sakamoto Y, Ogata A, Nagai F. Effects of prenatal exposure to styrene trimers on genital organs and hormones in male rats. Experimental Biology and Medicine 2007, 232(2):301-308.
    • (2007) Experimental Biology and Medicine , vol.232 , Issue.2 , pp. 301-308
    • Ohyama, K.1    Satoh, K.2    Sakamoto, Y.3    Ogata, A.4    Nagai, F.5
  • 51
    • 0036086124 scopus 로고    scopus 로고
    • Sonic hedgehog signaling from the urethral epithelium controls external genital development
    • Perriton CL, Powles N, Chiang C, Maconochie MK, Cohn MJ. Sonic hedgehog signaling from the urethral epithelium controls external genital development. Developmental Biology 2002, 247(1):26-46.
    • (2002) Developmental Biology , vol.247 , Issue.1 , pp. 26-46
    • Perriton, C.L.1    Powles, N.2    Chiang, C.3    Maconochie, M.K.4    Cohn, M.J.5
  • 52
    • 21044458903 scopus 로고    scopus 로고
    • Development of the mammalian urethra is controlled by FGFr2-IIIb
    • Petiot A, Perriton CL, Dickson C, Cohn MJ. Development of the mammalian urethra is controlled by FGFr2-IIIb. Development 2005, 132(10):2441-2450.
    • (2005) Development , vol.132 , Issue.10 , pp. 2441-2450
    • Petiot, A.1    Perriton, C.L.2    Dickson, C.3    Cohn, M.J.4
  • 56
    • 79955793281 scopus 로고    scopus 로고
    • Hypospadias risk and polymorphism in SRD5A2 and CYP17 genes: case-control study among Indian children
    • Samtani R, Bajpai M, Vashisht K, Ghosh PK, Saraswathy KN. Hypospadias risk and polymorphism in SRD5A2 and CYP17 genes: case-control study among Indian children. Journal of Urology 2011, 185(6):2334-2339.
    • (2011) Journal of Urology , vol.185 , Issue.6 , pp. 2334-2339
    • Samtani, R.1    Bajpai, M.2    Vashisht, K.3    Ghosh, P.K.4    Saraswathy, K.N.5
  • 57
    • 70450181794 scopus 로고    scopus 로고
    • Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development
    • Seifert AW, Bouldin CM, Choi KS, Harfe BD, Cohn MJ. Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development. Development 2009, 136(23):3949-3957.
    • (2009) Development , vol.136 , Issue.23 , pp. 3949-3957
    • Seifert, A.W.1    Bouldin, C.M.2    Choi, K.S.3    Harfe, B.D.4    Cohn, M.J.5
  • 58
    • 69049104244 scopus 로고    scopus 로고
    • Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development
    • Seifert AW, Yamaguchi T, Cohn MJ. Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development. Development 2009, 136(15):2643-2651.
    • (2009) Development , vol.136 , Issue.15 , pp. 2643-2651
    • Seifert, A.W.1    Yamaguchi, T.2    Cohn, M.J.3
  • 59
    • 4644299516 scopus 로고    scopus 로고
    • SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
    • 2
    • Sekido R, Bar I, Narvaez V, Penny G, Lovell-Badge R. SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors. Developmental Biology 2004, 15(274(2)):271-279.
    • (2004) Developmental Biology , vol.15 , Issue.274 , pp. 271-279
    • Sekido, R.1    Bar, I.2    Narvaez, V.3    Penny, G.4    Lovell-Badge, R.5
  • 63
    • 82255172520 scopus 로고    scopus 로고
    • Foetal exposure to phthalate esters and anogenital distance in male newborns.
    • , 10.1111/j.1365-2605.2011.01190.x
    • Suzuki Y., Yoshinaga J., Mizumoto Y., Serizawa S., Shiraishi H. Foetal exposure to phthalate esters and anogenital distance in male newborns. International Journal of Andrology 2012, 35(3):236-244. , 10.1111/j.1365-2605.2011.01190.x.
    • (2012) International Journal of Andrology , vol.35 , Issue.3 , pp. 236-244
    • Suzuki, Y.1    Yoshinaga, J.2    Mizumoto, Y.3    Serizawa, S.4    Shiraishi, H.5
  • 66
    • 0035992078 scopus 로고    scopus 로고
    • Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis
    • Suzuki K, Ogino Y, Murakami R, Satoh Y, Bachiller D, Yamada G. Embryonic development of mouse external genitalia: insights into a unique mode of organogenesis. Evolution and Development 2002, 4(2):133-141.
    • (2002) Evolution and Development , vol.4 , Issue.2 , pp. 133-141
    • Suzuki, K.1    Ogino, Y.2    Murakami, R.3    Satoh, Y.4    Bachiller, D.5    Yamada, G.6
  • 68
    • 0036796863 scopus 로고    scopus 로고
    • Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.
    • Tevosian, Sergei G., Albrecht Kenneth H., Crispino John D., Fujiwara Yuko, Eicher Eva M., Orkin Stuart H. Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development (Cambridge, England) 2002, 129(19):4627-4634.
    • (2002) Development (Cambridge, England) , vol.129 , Issue.19 , pp. 4627-4634
    • Tevosian1    Sergei, G.2    Albrecht Kenneth, H.3    Crispino John, D.4    Fujiwara Yuko5    Eicher Eva, M.6    Orkin Stuart, H.7
  • 70
    • 0033521967 scopus 로고    scopus 로고
    • Female development in mammals is regulated by Wnt-4 signalling.
    • , 10.1038/17068
    • Vainio S., Heikkilä M., Kispert A., Chin N., McMahon AP. Female development in mammals is regulated by Wnt-4 signalling. Nature 1999, 397(6718):405-409. , 10.1038/17068.
    • (1999) Nature , vol.397 , Issue.6718 , pp. 405-409
    • Vainio, S.1    Heikkilä, M.2    Kispert, A.3    Chin, N.4    McMahon, A.P.5
  • 71
    • 52949147097 scopus 로고    scopus 로고
    • Endocrine disruptors, genital development, and hypospadias
    • Wang MH, Baskin LS. Endocrine disruptors, genital development, and hypospadias. Journal of Andrology 2008, 29(5):499-505.
    • (2008) Journal of Andrology , vol.29 , Issue.5 , pp. 499-505
    • Wang, M.H.1    Baskin, L.S.2
  • 74
    • 0019412023 scopus 로고
    • Role of gonadal hormones in development of the sexual phenotypes
    • Wilson JD, Griffin JE, Leshin M, George FW. Role of gonadal hormones in development of the sexual phenotypes. Human Genetics 1981, 58(1):78-84.
    • (1981) Human Genetics , vol.58 , Issue.1 , pp. 78-84
    • Wilson, J.D.1    Griffin, J.E.2    Leshin, M.3    George, F.W.4
  • 75
    • 61349150511 scopus 로고    scopus 로고
    • Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium
    • Wu X, Ferrara C, Shapiro E, Grishina I. Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium. Gene Expression Patterns 2009, 9(4):224-230.
    • (2009) Gene Expression Patterns , vol.9 , Issue.4 , pp. 224-230
    • Wu, X.1    Ferrara, C.2    Shapiro, E.3    Grishina, I.4
  • 76
    • 0242329353 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of development of the external genitalia
    • Yamada G, Satoh Y, Baskin LS, Cunha GR. Cellular and molecular mechanisms of development of the external genitalia. Differentiation 2003, 71(8):445-460.
    • (2003) Differentiation , vol.71 , Issue.8 , pp. 445-460
    • Yamada, G.1    Satoh, Y.2    Baskin, L.S.3    Cunha, G.R.4
  • 77
    • 79955031296 scopus 로고    scopus 로고
    • Morphology of mouse external genitalia: implications for a role of estrogen in sexual dimorphism of the mouse genital tubercle
    • Yang JH, Menshenina J, Cunha GR, Place N, Baskin LS. Morphology of mouse external genitalia: implications for a role of estrogen in sexual dimorphism of the mouse genital tubercle. Journal of Urology 2010, 184(4 Suppl):1604-1609.
    • (2010) Journal of Urology , vol.184 , Issue.4 SUPPL , pp. 1604-1609
    • Yang, J.H.1    Menshenina, J.2    Cunha, G.R.3    Place, N.4    Baskin, L.S.5
  • 79
    • 2342592015 scopus 로고    scopus 로고
    • Anatomical studies of the fibroblast growth gactor-10 mutant, Sonic Hedge Hog mutant and androgen receptor mutant mouse genital tubercle
    • Yucel S, Liu W, Cordero D, Donjacour A, Cunha G, Baskin LS. Anatomical studies of the fibroblast growth gactor-10 mutant, Sonic Hedge Hog mutant and androgen receptor mutant mouse genital tubercle. Advances in Experimental Medicine and Biology 2004, 545:123-148.
    • (2004) Advances in Experimental Medicine and Biology , vol.545 , pp. 123-148
    • Yucel, S.1    Liu, W.2    Cordero, D.3    Donjacour, A.4    Cunha, G.5    Baskin, L.S.6
  • 81
    • 0346749680 scopus 로고    scopus 로고
    • The effect of oestrogen and testosterone on the urethral seam of the developing male mouse genital tubercle
    • Yucel S, Cavalcanti AG, Desouza A, Wang Z, Baskin LS. The effect of oestrogen and testosterone on the urethral seam of the developing male mouse genital tubercle. BJU International 2003, 92(9):1016-1021.
    • (2003) BJU International , vol.92 , Issue.9 , pp. 1016-1021
    • Yucel, S.1    Cavalcanti, A.G.2    Desouza, A.3    Wang, Z.4    Baskin, L.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.