Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development

Development

Volumn 136, Issue 15, 2009, Pages 2643-2651

  Seifert, Ashley W ^a   Yamaguchi, Terry ^b   Cohn, Martin J ^a,c  

^a University of Florida ^*  (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF FLORIDA   (United States)

Author keywords

Cloaca; Evolution; Fgf8; Genitalia; Wnt5a

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ECTODERM; EMBRYO; ENDODERM; EXTERNAL GENITAL DEVELOPMENT; FEMALE; GENE ACTIVATION; GENE ACTIVITY; GENE FUNCTION; GENE LOCATION; GENE TARGETING; GENETIC MARKER; GENITAL SYSTEM; GROWTH INHIBITION; INTRACELLULAR SPACE; MALE; MOUSE; NONHUMAN; ORGANOGENESIS; PENIS DEVELOPMENT; PHENOTYPE; PHYLOGENY; PRIORITY JOURNAL; URETHRA;

ANIMALS; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEIN 4; CELL SURVIVAL; CLOACA; ECTODERM; ENDODERM; FEMALE; FIBROBLAST GROWTH FACTOR 8; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENITALIA; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; MALE; MAMMALS; MICE; PENIS; PHYLOGENY; REPTILES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; WNT PROTEINS;

ALLIGATORINAE; AMNIOTA; EUTHERIA; MAMMALIA; METATHERIA; TESTUDINES;

EID: 69049104244     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.036830     Document Type: Article

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