Prenatal testosterone exposure permanently masculinizes anogenital distance, nipple development, and reproductive tract morphology in female sprague-dawley rats

Toxicological Sciences

Volumn 96, Issue 2, 2007, Pages 335-345

  Hotchkiss, Andrew K ^a,b   Lambright, Christy S ^b   Ostby, Joseph S ^b   Parks Saldutti, Louise ^c   Vandenbergh, John G ^a   Gray Jr , Leon E ^b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

AGD; Areola; Fetal androgen; Intrauterine position; Masculinization; Reproductive development

Indexed keywords

ANDROGEN; TESTOSTERONE;

AMNION FLUID; ANIMAL ANATOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANUS; ARTICLE; BODY POSITION; BREAST DEVELOPMENT; BREAST MALFORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FETUS; GENITAL MALFORMATION; GENITAL SYSTEM; GESTATIONAL AGE; HORMONE DETERMINATION; MALE; NONHUMAN; PREDICTION; PRENATAL EXPOSURE; PROSTATE; RAT; RELIABILITY; SEX DIFFERENCE; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; VIRILIZATION;

ABNORMALITIES, DRUG-INDUCED; ANAL CANAL; ANIMALS; ANIMALS, NEWBORN; ENDOCRINE DISRUPTORS; ESTRUS; FEMALE; FETUS; GENITALIA, FEMALE; GESTATIONAL AGE; MALE; NIPPLES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE; UTERUS; VAGINA; WEIGHT LOSS;

MAMMALIA; MUS; RATTUS;

EID: 33947245423     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm002     Document Type: Article

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