Administration of potentially antiandrogenic pesticides (procymidone, linuron, iprodione, chlozolinate, p,p′-DDE, and ketoconazole) and toxic substances (dibutyl- and diethylhexyl phthalate, PCB 169, and ethane dimethane sulphonate) during sexual differentiation produces diverse profiles of reproductive malformations in the male rat

Toxicology and Industrial Health

Volumn 15, Issue 2, 1999, Pages 94-118

  Wolf, Cynthia ^a   Lambright, Christy ^a   Mann, Peter ^b   Price, Matthew ^a   Cooper, Ralph L ^a   Ostby, Joseph ^a   Gray, L Earl ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

Author keywords

anti androgen; developmental reproductive toxicology; endocrine disruptor; inhibition of steroid synthesis; pesticides; phthalate; sex reversal; steroid receptors

Indexed keywords

ANTIANDROGEN; ETHANE; IPRODIONE; LINURON; PESTICIDE; PHTHALIC ACID DIBUTYL ESTER; POLYCHLORINATED BIPHENYL; PROCYMIDONE; TOXIC SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BINDING AFFINITY; BIOACCUMULATION; CONFERENCE PAPER; CONTROLLED STUDY; DEATH; FEMALE; MALE; MOLECULAR DYNAMICS; NONHUMAN; RAT; RECEPTOR BINDING; REPRODUCTIVE TOXICITY; SEX DIFFERENTIATION;

AMINOIMIDAZOLE CARBOXAMIDE; ANDROGEN ANTAGONISTS; ANIMALS; BICYCLO COMPOUNDS; DIBUTYL PHTHALATE; DICHLORODIPHENYL DICHLOROETHYLENE; DIETHYLHEXYL PHTHALATE; FEMALE; GENITALIA, MALE; GONADAL STEROID HORMONES; HYDANTOINS; KETOCONAZOLE; LINURON; MALE; OXAZOLES; PESTICIDES; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; SEX DIFFERENTIATION; XENOBIOTICS;

ANIMALIA;

EID: 0343090362     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/074823379901500109     Document Type: Article

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