Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice

Journal of Steroid Biochemistry and Molecular Biology

Volumn 132, Issue 3-5, 2012, Pages 262-270

  Zhang, Xin ^a,b   Bai, Qianming ^a,c   Kakiyama, Genta ^a   Xu, Leyuan ^a   Kim, Jin Kyung ^a   Pandak Jr , William M ^a   Ren, Shunlin ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FUDAN UNIVERSITY   (China)

^c FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

25 Hydroxycholesterol; Cytosolic sulfotransferase 2B1b; Liver X receptors; Oxysterol; Oxysterol sulfation; Proliferating cell nuclear antigen

Indexed keywords

25 HYDROXYCHOLESTEROL; 5 CHOLESTEN 3BETA 25 DIOL 3 SULFATE; ABC TRANSPORTER A1; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CHECKPOINT KINASE 2; CYCLIN A; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; STEROL DERIVATIVE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; WT1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; DNA REPLICATION; DOSE RESPONSE; GENE EXPRESSION; HALF LIFE TIME; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIPOGENESIS; LIVER CELL; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CHOLESTEROL; CHOLESTEROL ESTERS; DNA REPLICATION; GENE EXPRESSION REGULATION; HYDROCARBONS, FLUORINATED; HYDROXYCHOLESTEROLS; LIVER; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; SIGNAL TRANSDUCTION; SULFONAMIDES; SULFOTRANSFERASES; TISSUE DISTRIBUTION; UP-REGULATION;

MUS;

EID: 84865547968     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.06.001     Document Type: Article

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