Transport of cholesterol into mitochondria is rate-limiting for bile acid synthesis via the alternative pathway in primary rat hepatocytes

Journal of Biological Chemistry

Volumn 277, Issue 50, 2002, Pages 48158-48164

  Pandak, William M ^a,b   Ren, Shunlin ^a   Marques, Dalila ^a   Hall, Elizabeth ^a   Redford, Kaye ^a   Mallonee, Darrell ^b   Bohdan, Patricia ^b   Heuman, Douglas ^a   Gill, Gregorio ^b   Hylemon, Phillip ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CHOLESTEROL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEINS;

GENE ENCODING;

BIOCHEMISTRY;

CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; STEROL 27 HYDROXYLASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BILE ACID SYNTHESIS; CATALYSIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; LIVER CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; CHOLESTEROL; CYTOCHROME P-450 CYP27A1; GENE EXPRESSION; HEPATOCYTES; MALE; MICROSOMES, LIVER; MITOCHONDRIA; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; STEROID HYDROXYLASES;

ANIMALIA;

EID: 0037073676     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205244200     Document Type: Article

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